During viral infections, brain tissue–resident memory T cells (bTRM) prevent fatal brain infection after acquiring perforin- and IFN-γ–dependent effector functions through a pathway that involves presentation of cognate antigen on MHC-I.
Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection
K. Steinbach,I. Vincenti,M. Kreutzfeldt,Nicolas Page,A. Muschaweckh,Ingrid Wagner,I. Drexler,D. Pinschewer,T. Korn,D. Merkler
Published 2016 in Journal of Experimental Medicine
ABSTRACT
PUBLICATION RECORD
- Publication year
2016
- Venue
Journal of Experimental Medicine
- Publication date
2016-07-25
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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