Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Circulation

• Publication date

  1998-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/01.CIR.98.22.2422PMID 9832487
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inwardly rectifying single-channel and whole cell K+ currents in rat ventricular myocytes

  2005cited by this paper
• Inward rectifier potassium channels.

  1997cited by this paper
• Differential expression of voltage-gated K+ channel genes in left ventricular remodeled myocardium after experimental myocardial infarction.

  1996cited by this paper
• TWIK‐1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure.

  1996cited by this paper
• Differences between outward currents of human atrial and subepicardial ventricular myocytes.

  1996cited by this paper
• Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

  1996cited by this paper
• Dimerization of TWIK‐1 K+ channel subunits via a disulfide bridge.

  1996cited by this paper
• Membrane Depolarization Inhibits Kv1.5 Voltage-gated K Channel Gene Transcription and Protein Expression in Pituitary Cells (*)

  1995cited by this paper
• Characterization of and modulation by a beta-subunit of a human maxi KCa channel cloned from myometrium.

  1995cited by this paper
• Differential expression of voltage-gated K+ channel subunits in adult rat heart. Relation to functional K+ channels?

  1995cited by this paper
• Cloning, localization, and functional expression of a human brain inward rectifier potassium channel (hIRK1).

  1995cited by this paper
• Cloning and functional expression of an inwardly rectifying K+ channel from human atrium.

  1995cited by this paper
• Inward rectifier K+ channel from human heart and brain: cloning and stable expression in a human cell line.

  1995cited by this paper
• Characterization of inwardly rectifying K+ channel in human cardiac myocytes. Alterations in channel behavior in myocytes isolated from patients with idiopathic dilated cardiomyopathy.

  1995cited by this paper
• Cloning a novel human brain inward rectifier potassium channel and its functional expression in Xenopus oocytes

  1994cited by this paper
• Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats.

  1994cited by this paper
• Molecular cloning and expression of a human heart inward rectifier potassium channel.

  1994cited by this paper
• Primary structure and characterization of a small-conductance inwardly rectifying potassium channel from human hippocampus.

  1994cited by this paper
• Cloning and expression of a novel human brain inward rectifier potassium channel.

  1994cited by this paper
• Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification

  1994cited by this paper
• Quantitation of changes in the expression of multiple genes by simultaneous polymerase chain reaction.

  1993cited by this paper
• Inwardly rectifying potassium current in rat fetal and neonatal ventricular cardiomyocytes.

  1993cited by this paper
• Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure.

  1993cited by this paper
• Potassium currents in isolated human atrial and ventricular cardiocytes.

  1993cited by this paper
• Delayed rectifier outward current and repolarization in human atrial myocytes.

  1993cited by this paper
• Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure.

  1992cited by this paper
• Developmental increases in the inwardly rectifying potassium current of rat ventricular myocytes.

  1992cited by this paper
• Single-channel recording of inwardly rectifying potassium currents in developing myocardium.

  1991cited by this paper
• Three different potassium channels in human atrium. Contribution to the basal potassium conductance.

  1990cited by this paper
• Developmental increases in the inwardly-rectifying K+ current of embryonic chick ventricular myocytes.

  1990cited by this paper
• Comparison of potassium currents in rabbit atrial and ventricular cells.

  1988cited by this paper
• Ionic basis of the different action potential configurations of single guinea‐pig atrial and ventricular myocytes.

  1985cited by this paper
• Cellular electrophysiologic abnormalities of diseased human ventricular myocardium.

  1983cited by this paper

• A Better Understanding of Atrial-like and Ventricular-like Action Potentials in Stem Cell-Derived Cardiomyocytes: The Underestimated Role of the L-Type Ca2+ Current

  2025cites this paper
• Cardiac arrhythmias in fish induced by natural and anthropogenic changes in environmental conditions.

  2024cites this paper
• Alleviating the Effects of Short QT Syndrome Type 3 by Allele-Specific Suppression of the KCNJ2 Mutant Allele

  2024cites this paper
• Zebrafish as a Model System for Brugada Syndrome

  2024cites this paper
• Research progress of two-pore potassium channel in myocardial ischemia-reperfusion injury

  2024cites this paper
• A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes

  2023cites this paper
• Injection of IK1 through dynamic clamp can make all the difference in patch-clamp studies on hiPSC-derived cardiomyocytes

  2023cites this paper
• Sildenafil affects the human Kir2.1 and Kir2.2 channels at clinically relevant concentrations: Inhibition potentiated by low Ba2+

  2023cites this paper
• Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development

  2023influential citation
• Pro-arrhythmic effects of gain-of-function potassium channel mutations in the short QT syndrome

  2023cites this paper
• Predicting Heart Cell Types by Using Transcriptome Profiles and a Machine Learning Method

  2022cites this paper
• Ionic currents underlying different patterns of electrical activity in working cardiac myocytes of mammals and non-mammalian vertebrates.

  2022cites this paper
• Pro-Arrhythmic Effects of Discontinuous Conduction at the Purkinje Fiber-Ventricle Junction Arising From Heart Failure-Induced Ionic Remodeling – Insights From Computational Modelling

  2022cites this paper
• Investigation of the Effects of the Short QT Syndrome D172N Kir2.1 Mutation on Ventricular Action Potential Profile Using Dynamic Clamp

  2022cites this paper
• Transcriptional profiles of genes related to electrophysiological function in Scn5a +/− murine hearts

  2021cites this paper
• MIAT, a potent CVD-promoting lncRNA

  2021cites this paper
• Diabetes-induced changes in cardiac voltage-gated ion channels

  2021cites this paper
• Cardiac potassium inward rectifier Kir2: Review of structure, regulation, pharmacology, and arrhythmogenesis

  2021cites this paper
• Two-Pore-Domain Potassium (K2P-) Channels: Cardiac Expression Patterns and Disease-Specific Remodelling Processes

  2021influential citation
• Contribution of K2P Potassium Channels to Cardiac Physiology and Pathophysiology

  2021cites this paper
• Excitation-contraction coupling and calcium release in atrial muscle

  2021cites this paper
• Protective effect of apocynin on oxidative damage of inward rectifier potassium current in rabbit left atrial myocytes

  2020cites this paper
• Hypercholesterolemia Induces Up-regulation of K ACh Cardiac Currents via a Mechanism Independent of Phosphatidylinositol 4,5-Bisphosphate and G (cid:1)(cid:2) *

  2020cites this paper
• Dynamic clamp in electrophysiological studies on stem cell-derived cardiomyocytes-why and how?

  2020cites this paper
• DNA Damage-Free iPS Cells Exhibit Potential to Yield Competent Cardiomyocytes.

  2020cites this paper
• Ultrarapid Delayed Rectifier K+ Channelopathies in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

  2020cites this paper
• Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents

  2020cites this paper
• Investigation of antiarrhythmic and proarrhythmic mechanisms in modified systems with molecular biological methods

  2019cites this paper
• Intracellular cardiomyocytes potential recording by planar electrode array and fibroblasts co-culturing on multi-modal CMOS chip.

  2019cites this paper
• Physiology and Molecular Biology of Ion Channels Underlying Ventricular Repolarization of the Mammalian Heart

  2019cites this paper
• Post-Myocardial Infarction and Exercise Training on Myosin Heavy Chain and Cardiac Function

  2019cites this paper
• Long non-coding RNAs as new regulators of cardiac electrophysiology and arrhythmias: Molecular mechanisms, therapeutic implications and challenges.

  2019cites this paper
• Metabolic modulators as a treatment of atrial fibrillation

  2019cites this paper
• Cardiac Kir2.1 and NaV1.5 Channels Traffic Together to the Sarcolemma to Control Excitability

  2018cites this paper
• Applications of Dynamic Clamp to Cardiac Arrhythmia Research: Role in Drug Target Discovery and Safety Pharmacology Testing

  2018cites this paper
• 94 – Andersen-Tawil Syndrome

  2018cites this paper
• Inward Rectifier Potassium Channels (Kir2.x) and Caveolin-3 Domain–Specific Interaction: Implications for Purkinje Cell–Dependent Ventricular Arrhythmias

  2018cites this paper
• Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes

  2018influential citation
• Characterization of a Human Induced Pluripotent Stem Cell–Derived Cardiomyocyte Model for the Study of Variant Pathogenicity: Validation of a KCNJ2 Mutation

  2017cites this paper
• Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp

  2017cites this paper
• Alternans in atria: Mechanisms and clinical relevance.

  2017cites this paper
• Atrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria

  2017cites this paper
• Dual Mechanism for Inhibition of Inwardly Rectifying Kir2.x Channels by Quinidine Involving Direct Pore Block and PIP2-interference

  2017cites this paper
• The inward rectifier current inhibitor PA‐6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models

  2017cites this paper
• Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP2 interference

  2017cites this paper
• Molecular Pathophysiology of Congenital Long QT Syndrome.

  2017cites this paper
• Flecainide ameliorates arrhythmogenicity through NCX flux in Andersen-Tawil syndrome-iPS cell-derived cardiomyocytes

  2017cites this paper
• Inward rectifying potassium currents resolved into components: modeling of complex drug actions

  2017cites this paper
• Pharmacological inhibition of IK 1 by PA‐6 in isolated rat hearts affects ventricular repolarization and refractoriness

  2016cites this paper
• Potassium Channel Remodeling in Heart Disease.

  2016cites this paper
• Heterogeneity of clinical syndromes related to loss of function mutations in KCNJ2

  2016cites this paper
• Transmural gradients in ion channel and auxiliary subunit expression.

  2016influential citation
• Arrhythmogenic and metabolic remodelling of failing human heart

  2016cites this paper
• Effect of ethanol and acetaldehyde at clinically relevant concentrations on atrial inward rectifier potassium current IK1: separate and combined effect.

  2016cites this paper
• The electrophysiological development of cardiomyocytes.

  2016cites this paper
• Effects of propafenone on KCNH2-linked short QT syndrome: A modelling study

  2016cites this paper
• Antiarrhythmic principle of SK channel inhibition in atrial fibrillation.

  2015cites this paper
• Computational Simulation of an Electrophysiological Human Heart Failure Model with an Early AfterDepolarization Arrhythmia Application

  2015cites this paper
• Regional variation of the inwardly rectifying potassium current in the canine heart and the contributions to differences in action potential repolarization.

  2015cites this paper
• Combined inhibition of key potassium currents has different effects on cardiac repolarization reserve and arrhythmia susceptibility in dogs and rabbits.

  2015cites this paper
• microRNAs and Cardiovascular Remodeling.

  2015cites this paper
• The mechanisms of calcium cycling and action potential dynamics in cardiac alternans.

  2015cites this paper
• Ion Channels in the Heart.

  2015cites this paper
• Andersen – Tawil Syndrome : A Retrospective Analysis of Clinical and Electrocardiographic Characteristics

  2015cites this paper
• Biophysics and Molecular Biology of Cardiac Ion Channels for the Safety Pharmacologist.

  2015cites this paper
• Molecular Investigation into the Human Atrioventricular Node in Heart Failure

  2015cites this paper
• Protein assemblies of sodium and inward rectifier potassium channels control cardiac excitability and arrhythmogenesis.

  2015cites this paper
• Real-time simulation of IK1 in cardiomyocytes derived from human induced pluripotent stem cells

  2015cites this paper
• Andersen-Tawil Syndrome

  2015cites this paper
• Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1

  2015influential citation
• Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224

  2014cites this paper
• Attenuation of Cardiac Fibrillation Vulnerability by n-3 Polyunsaturated Fatty Acids in a Rat Model of Cardiomyopathy

  2014cites this paper
• The role of transcription factors in the formation of an arrhythmogenic substrate in congestive human heart failure.

  2014cites this paper
• Dual effect of ethanol on inward rectifier potassium current IK1 in rat ventricular myocytes.

  2014cites this paper
• MicroRNAs and cardiovascular medicine

  2014cites this paper
• Agonist of inward rectifier K+ channels enhances the protection of ischemic postconditioning in isolated rat hearts

  2014cites this paper
• The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias

  2014cites this paper
• Carbon monoxide inhibits inward rectifier potassium channels in cardiomyocytes

  2014cites this paper
• Lessons from the heart: mirroring electrophysiological characteristics during cardiac development to in vitro differentiation of stem cell derived cardiomyocytes.

  2014cites this paper
• 29. MicroRNAs and Cardiovascular Diseases

  2013cites this paper
• Electrophysiological Remodeling in Heart Failure

  2013cites this paper
• Cardiac characteristics and long-term outcome in Andersen-Tawil syndrome patients related to KCNJ2 mutation.

  2013cites this paper
• MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation.

  2013cites this paper
• Receptor Trafficking and the Regulation of Synaptic Plasticity by SUMO

  2013cites this paper
• Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs

  2013influential citation
• Function and Mechanism of Polarized Targeting of Neuronal Membrane Proteins

  2013cites this paper
• miRNA in the regulation of ion channel/transporter expression.

  2013cites this paper
• The interaction of caveolin 3 protein with the potassium inward rectifier channel Kir2.1. PHYSIOLOGY AND PATHOLOGY RELATED TO LONG QT SYNDROME 9 (LQT9).

  2013cites this paper
• The Role of MicroRNA Regulation of Cardiac Ion Channel in Arrhythmia

  2013cites this paper
• Andersen-Tawil and Timothy Syndromes

  2013cites this paper
• Principios básicos de las nuevas estrategias farmacológicas antiarrítmicas en fibrilación auricular

  2012cites this paper
• Molecular determinants of different gating mechanisms in inwardly-rectifying potassium channels

  2012cites this paper
• Cardiomyocytes derived from human induced pluripotent stem cells as models for normal and diseased cardiac electrophysiology and contractility.

  2012influential citation
• Arrhythmogenic remodelling of activation and repolarization in the failing human heart.

  2012cites this paper
• Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells.

  2012cites this paper
• Revisit of the Cardiac Inward Rectifier Potassium Current IK1

  2012cites this paper
• [Basic mechanisms of the new antiarrhythmic drugs in atrial fibrillation].

  2012cites this paper
• Hypercholesterolemia Induces Up-regulation of KACh Cardiac Currents via a Mechanism Independent of Phosphatidylinositol 4,5-Bisphosphate and Gβγ*

  2011cites this paper
• Mechanism underlying bradycardia and long QT 2 related arrhythmias: Interplay between Ca2+ overload and electrical dysfunction

  2011cites this paper
• Monogenic atrial fibrillation as pathophysiological paradigms

  2011cites this paper