Biofilm Formation by Streptococcus pneumoniae: Role of Choline, Extracellular DNA, and Capsular Polysaccharide in Microbial Accretion

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Bacteriology

• Publication date

  2006-08-25

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1128/JB.00673-06PMID 16936041PMCID PMC1636320
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phenotypic Characterization of Streptococcus pneumoniae Biofilm Development

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• Illustration of Pneumococcal Polysaccharide Capsule during Adherence and Invasion of Epithelial Cells

  2005cited by this paper
• Analysis of the Genetic Structure of Nontypeable Pneumococcal Strains Isolated from Conjunctiva

  2005cited by this paper
• Staphylococcus aureus Develops an Alternative, ica-Independent Biofilm in the Absence of the arlRS Two-Component System

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• Allelic Variation of Polymorphic Locus lytB, Encoding a Choline-Binding Protein, from Streptococci of the Mitis Group

  2005cited by this paper
• Surfacing views of biofilm biology.

  2005cited by this paper
• Neisseria meningitidis Lactate Permease Is Required for Nasopharyngeal Colonization

  2005cited by this paper
• Biofilms: the matrix revisited.

  2005cited by this paper
• Quorum sensing in streptococcal biofilm formation.

  2005cited by this paper
• Mechanisms of action of newer antibiotics for Gram-positive pathogens.

  2005cited by this paper
• Choline-Binding Protein D (CbpD) in Streptococcus pneumoniae Is Essential for Competence-Induced Cell Lysis

  2005cited by this paper
• Biofilm formation and dispersal and the transmission of human pathogens.

  2005cited by this paper
• DNA Binding-Uptake System: a Link between Cell-to-Cell Communication and Biofilm Formation

  2005cited by this paper
• Capsule-Negative Staphylococcus aureus Induces Chronic Experimental Mastitis in Mice

  2005cited by this paper
• Bacterial biofilms: from the Natural environment to infectious diseases

  2004cited by this paper
• Exploring the physiological state of continental Antarctic endolithic microorganisms by microscopy.

  2004cited by this paper
• Biofilm Mode of Growth of Streptococcus intermedius Favored by a Competence-Stimulating Signaling Peptide

  2004cited by this paper
• Model System for Growing and Quantifying Streptococcus pneumoniae Biofilms In Situ and in Real Time

  2004cited by this paper
• Choline-Binding Proteins

  2004cited by this paper
• Microstructural Characterization of Cyanobacterial Mats from the McMurdo Ice Shelf, Antarctica

  2004cited by this paper
• Recent trends on the molecular biology of pneumococcal capsules, lytic enzymes, and bacteriophage.

  2004influential reference
• Mechanisms of Carriage

  2004cited by this paper
• 9.12 n&v 679 MH

  2004cited by this paper
• A Sticky Business: the Extracellular Polymeric Substance Matrix of Bacterial Biofilms

  2004cited by this paper
• Cell Wall Hydrolases

  2004cited by this paper
• Streptococcus pneumoniae colonisation: the key to pneumococcal disease.

  2004cited by this paper
• Release of DNA into the medium by competent Streptococcus pneumoniae: kinetics, mechanism and stability of the liberated DNA

  2004cited by this paper
• The pathogenesis of streptococcal infections: from Tooth decay to meningitis

  2003cited by this paper
• Construction of the mobilizable plasmid pMV158GFP, a derivative of pMV158 that carries the gene encoding the green fluorescent protein.

  2003cited by this paper
• Competence-Induced Cells of Streptococcuspneumoniae Lyse Competence-Deficient Cells of the SameStrain duringCocultivation

  2003influential reference
• Role of airway surface liquid and submucosal glands in cystic fibrosis lung disease.

  2003cited by this paper
• Quorum sensing and biofilm formation in Streptococcal infections.

  2003cited by this paper
• Spontaneous sequence duplications within capsule genes cap8E and tts control phase variation in Streptococcus pneumoniae serotypes 8 and 37.

  2003cited by this paper
• Bacterial biofilms: an emerging link to disease pathogenesis.

  2003cited by this paper
• Novel Two-Component Regulatory System Involved in Biofilm Formation and Acid Resistance in Streptococcus mutans

  2002cited by this paper
• Extracellular-peptide control of competence for genetic transformation in Streptococcus pneumoniae.

  2002cited by this paper
• A Quorum-Sensing Signaling System Essential for Genetic Competence in Streptococcus mutans Is Involved in Biofilm Formation

  2002cited by this paper
• Induction of natural competence in Streptococcus pneumoniae triggers lysis and DNA release from a subfraction of the cell population

  2002influential reference
• Extracellular DNA required for bacterial biofilm formation.

  2002cited by this paper
• Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms

  2002cited by this paper
• Purification and Polar Localization of Pneumococcal LytB, a Putative Endo-β-N-Acetylglucosaminidase: the Chain-Dispersing Murein Hydrolase

  2002cited by this paper
• Positive role of peptidoglycan breaks in lactococcal biofilm formation

  2002cited by this paper
• Molecular Characterization of the Pneumococcal Teichoic Acid Phosphorylcholine Esterase

  2001cited by this paper
• Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniae

  2001cited by this paper
• Comparison of nasal pH values in black and white individuals with normal and high blood pressure.

  2001cited by this paper
• Genome of the Bacterium Streptococcus pneumoniae Strain R6

  2001cited by this paper
• Spontaneous sequence duplication within an open reading frame of the pneumococcal type 3 capsule locus causes high‐frequency phase variation

  2001cited by this paper
• Annotated Draft Genomic Sequence from a Streptococcus pneumoniae Type 19F Clinical Isolate

  2001cited by this paper
• Mosaic Genes and Mosaic Chromosomes: Intra- and Interspecies Genomic Variation of Streptococcus pneumoniae

  2001cited by this paper
• Role of Novel Choline Binding Proteins in Virulence of Streptococcus pneumoniae

  2000cited by this paper
• Temperature Profile in the Nasal Cavity

  2000cited by this paper
• Phosphocholine of pneumococcal teichoic acids: role in bacterial physiology and pneumococcal infection.

  2000cited by this paper
• Streptococcus gordonii Biofilm Formation: Identification of Genes that Code for Biofilm Phenotypes

  2000cited by this paper
• Cross‐regulation of competence pheromone production and export in the early control of transformation in Streptococcus pneumoniae

  2000cited by this paper
• Bacterial biofilms: a common cause of persistent infections.

  1999cited by this paper
• A Single Gene (tts) Located outside the cap Locus Directs the Formation of Streptococcus pneumoniae Type 37 Capsular Polysaccharide

  1999cited by this paper
• LytB, a novel pneumococcal murein hydrolase essential for cell separation

  1999cited by this paper
• Effect of Intrastrain Variation in the Amount of Capsular Polysaccharide on Genetic Transformation of Streptococcus pneumoniae: Implications for Virulence Studies of Encapsulated Strains

  1999cited by this paper
• Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis

  1998influential reference
• Systematic identification of essential genes by in vitro mariner mutagenesis.

  1998cited by this paper
• The use of Sorbarod biofilms to study the antimicrobial susceptibility of a strain of Streptococcus pneumoniae.

  1997cited by this paper
• A purified mariner transposase is sufficient to mediate transposition in vitro

  1996cited by this paper
• Microbial biofilms.

  1995cited by this paper
• Six newly recognized types of Streptococcus pneumoniae

  1995cited by this paper
• Molecular basis of the optochin‐sensitive phenotype of pneumococcus: characterization of the genes encoding the F0 complex of the Streptococcus pneumoniaeStreptococcus oralis H+‐ATPases

  1994cited by this paper
• Procedures in electron microscopy

  1993cited by this paper
• Isolation, characterization and physiological properties of an autolytic-deficient mutant of Streptococcus pneumoniae

  1986cited by this paper
• Searching for autolysin functions. Characterization of a pneumococcal mutant deleted in the lytA gene.

  1986cited by this paper
• Some aspects of the pneumococcal carrier state.

  1986cited by this paper
• A rapid procedure to detect the autolysin phenotype in Streptococcus pneumoniae

  1985cited by this paper
• Interaction of the pneumococcal amidase with lipoteichoic acid and choline.

  1985cited by this paper
• Growth characteristics of group A streptococci in a new chemically defined medium

  1980influential reference
• Role of the pneumococcal autolysin (murein hydrolase) in the release of progeny bacteriophage and in the bacteriophage-induced lysis of the host cells

  1977cited by this paper
• Suppression of the Lytic and Bactericidal Effects of Cell Wall-Inhibitory Antibiotics

  1976cited by this paper
• Characterization of some pneumococcal bacteriophages

  1976cited by this paper
• Biological consequences of the replacement of choline by ethanolamine in the cell wall of Pneumococcus: chanin formation, loss of transformability, and loss of autolysis.

  1968cited by this paper
• A study of the genetic material determining an enzyme activity in Pneumococcus

  1960cited by this paper
• A study of the genetic material determining an enzyme in Pneumococcus.

  1960cited by this paper

• Pathogenic Role of β‐Endo‐N‐Acetylglucosaminidase (LytB) in Streptococcus pneumoniae: Functional Insights Into a Choline‐Binding Cell Wall Hydrolase

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• “The NET effect”: Neutrophil extracellular traps—a potential key component of the dysregulated host immune response in sepsis

  2025cites this paper
• Release of extracellular DNA by Pseudomonas sp. as a major determinant for biofilm switching and an early indicator for cell population control

  2025cites this paper
• Biofilm formation during pneumococcal carriage imprints naturally acquired humoral immunity

  2025cites this paper
• Formation Dynamics of Honeycomb‐Like Capsules and Sponge‐Like Biofilms in Micrococcus Reveal a Novel Heavy Metal Avoidance Strategy

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• Streptococcus pneumoniae accessory capsular genes modulate fitness, pathogenicity and immune evasion

  2025cites this paper
• Identification of a novel gene associated with group B Streptococcus persister cell formation and biofilm production

  2025cites this paper
• Streptococcus suis serovar 9 responses to elevated temperature and co-culture with Glaesserella parasuis.

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• Host Serum Amyloid A1 Facilitates Streptococcus pneumoniae Adaptation to Acidic Stress Induced by Pneumococcal Anaerobic Metabolism

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• Label-free microscopy enables high-throughput identification of genes controlling biofilm development

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• SOS-Inducing Drugs Trigger Nucleic Acid Release and Biofilm Formation in Gram-Negative Bacteria

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• Biological puzzles solved by using Streptococcus pneumoniae: a historical review of the pneumococcal studies that have impacted medicine and shaped molecular bacteriology

  2024cites this paper
• Bacterial surface lipoproteins mediate epithelial microinvasion by Streptococcus pneumoniae

  2024cites this paper
• Point mutations in functionally diverse genes are associated with increased natural DNA transformation in multidrug resistant Streptococcus pneumoniae

  2024cites this paper
• Identification and genetic engineering of pneumococcal capsule-like polysaccharides in commensal oral streptococci

  2024cites this paper
• Transcriptional regulation of TacL-mediated lipoteichoic acids biosynthesis by ComE during competence impacts pneumococcal transformation

  2024cites this paper
• Streptococcus Pneumoniae Teichoic Acids

  2024cites this paper
• eDNA Provides a Scaffold for Autoaggregation of B. subtilis in Bacterioplankton Suspension

  2023cites this paper
• Rewiring capsule production by CRISPRi-based genetic oscillators demonstrates a functional role of phenotypic variation in pneumococcal-host interactions

  2023cites this paper
• Enzybiotic-mediated antimicrobial functionalization of polyhydroxyalkanoates

  2023influential citation
• Type II bacterial toxin–antitoxins: hypotheses, facts, and the newfound plethora of the PezAT system

  2023cites this paper
• Streptococcal peptides and their roles in host-microbe interactions

  2023cites this paper
• Synthetic genetic oscillators demonstrate the functional importance of phenotypic variation in pneumococcal-host interactions

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• The choline-binding proteins PspA, PspC, and LytA of Streptococcus pneumoniae and their interaction with human endothelial and red blood cells

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• Biofilm Potentiates Cancer-Promoting Effects of Tumor-Associated Macrophages in a 3D Multi-Faceted Tumor Model.

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• Monoclonal antibodies that target extracellular DNABII proteins or the type IV pilus of nontypeable Haemophilus influenzae (NTHI) worked additively to disrupt 2-genera biofilms

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• Function analysis of choline binding domains (CBDs) of LytA, LytC and CbpD in biofilm formation of Streptococcus pneumoniae.

  2022cites this paper
• Inhibition and eradication of bacterial biofilm using polymeric materials.

  2022cites this paper
• How Streptococcus suis escapes antibiotic treatments

  2022cites this paper
• The biogeography of infection revisited

  2022cites this paper
• The Helicobacter pylori UvrC Nuclease Is Essential for Chromosomal Microimports after Natural Transformation

  2022cites this paper
• Targeting the Holy Triangle of Quorum Sensing, Biofilm Formation, and Antibiotic Resistance in Pathogenic Bacteria

  2022cites this paper
• Dynamics, gene transfer, and ecological function of intracellular and extracellular DNA in environmental microbiome

  2022cites this paper
• Intra-Species Interactions in Streptococcus pneumoniae Biofilms

  2022cites this paper
• Differentiation of otitis media-causing bacteria and biofilms via Raman spectroscopy and optical coherence tomography

  2022cites this paper
• The choline-binding proteins PspA, PspC and LytA of Streptococcus pneumoniae and their role on host cellular adhesion and damage

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• Interrogation of the contribution of (endo)lysin domains to tune their bacteriolytic efficiency provides a novel clue to design superior antibacterials.

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  2020cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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