Mechanotransduction: Tuning Stem Cells Fate

It is a general concern that the success of regenerative medicine-based applications is based on the ability to recapitulate the molecular events that allow stem cells to repair the damaged tissue/organ. To this end biomaterials are designed to display properties that, in a precise and physiological-like fashion, could drive stem cell fate both in vitro and in vivo. The rationale is that stem cells are highly sensitive to forces and that they may convert mechanical stimuli into a chemical response. In this review, we describe novelties on stem cells and biomaterials interactions with more focus on the implication of the mechanical stimulation named mechanotransduction.

• Publication year

  2011

• Venue

  Journal of Functional Biomaterials

• Publication date

  2011-06-01

• Fields of study

  Biology, Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.3390/jfb2020067PMID 24956164PMCID 4030896
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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