Precursor Lesions for Sporadic Pancreatic Cancer: PanIN, IPMN, and MCN

Pancreatic cancer is still a dismal disease. The high mortality rate is mainly caused by the lack of highly sensitive and specific diagnostic tools, and most of the patients are diagnosed in an advanced and incurable stage. Knowledge about precursor lesions for pancreatic cancer has grown significantly over the last decade, and nowadays we know that mainly three lesions (PanIN, and IPMN, MCN) are responsible for the development of pancreatic cancer. The early detection of these lesions is still challenging but provides the chance to cure patients before they might get an invasive pancreatic carcinoma. This paper focuses on PanIN, IPMN, and MCN lesions and reviews the current level of knowledge and clinical measures.

• Publication year

  2014

• Venue

  BioMed Research International

• Publication date

  2014-03-24

• Fields of study

  Medicine

• Identifiers
  DOI 10.1155/2014/474905PMID 24783207PMCID 3982269
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cytological criteria of high‐grade epithelial atypia in the cyst fluid of pancreatic intraductal papillary mucinous neoplasms

  2014cited by this paper
• Frequency of Kras Mutations in Pancreatic Intraductal Neoplasias Associated with Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis : A Meta-Analysis 1

  2014cited by this paper
• Mutant TP53 in duodenal samples of pancreatic juice from patients with pancreatic cancer or high-grade dysplasia.

  2013cited by this paper
• Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

  2013cited by this paper
• Preoperative Histological Subtype Classification of Intraductal Papillary Mucinous Neoplasms (IPMN) by Pancreatic Juice Cytology With MUC Stain

  2013cited by this paper
• The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant

  2013cited by this paper
• Pathohistological Subtype Predicts Survival in Patients With Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

  2013cited by this paper
• Evaluation of survival in patients after pancreatic head resection for ductal adenocarcinoma

  2013cited by this paper
• [Intraductal papillary mucinous neoplasm of the pancreas (IPMN)--standards and new aspects].

  2013cited by this paper
• Cyst Fluid Carcinoembryonic Antigen Is an Accurate Diagnostic Marker of Pancreatic Mucinous Cysts: Erratum

  2013cited by this paper
• Expression of MUC4 Mucin Is Observed Mainly in the Intestinal Type of Intraductal Papillary Mucinous Neoplasm of the Pancreas

  2013cited by this paper
• mAb Das-1 is specific for high-risk and malignant intraductal papillary mucinous neoplasm (IPMN)

  2013cited by this paper
• Intraduktale papillär-muzinöse Neoplasien (IPMN) des Pankreas – Standards und neue Aspekte

  2013cited by this paper
• EUS-guided pancreatic fluid aspiration for DNA analysis of KRAS and GNAS mutations for the evaluation of pancreatic cystic neoplasia: a pilot study.

  2013cited by this paper
• Precancerous lesions of the pancreas.

  2013cited by this paper
• Different subtypes of intraductal papillary mucinous neoplasm in the pancreas have distinct pathways to pancreatic cancer progression

  2012cited by this paper
• Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts

  2012cited by this paper
• I and J

  2012cited by this paper
• Invasive mucinous cystic neoplasms of the pancreas.

  2012cited by this paper
• International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas.

  2012cited by this paper
• Cancer statistics, 2012

  2012cited by this paper
• 851 resected cystic tumors of the pancreas: a 33-year experience at the Massachusetts General Hospital.

  2012cited by this paper
• Genome-Wide CpG Island Profiling of Intraductal Papillary Mucinous Neoplasms of the Pancreas

  2011cited by this paper
• Clinicopathological Features and Prognosis of Mucinous Cystic Neoplasm With Ovarian-Type Stroma: A Multi-Institutional Study of the Japan Pancreas Society

  2011cited by this paper
• Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

  2011cited by this paper
• Cyst Fluid Interleukin-1β (IL1β) Levels Predict the Risk of Carcinoma in Intraductal Papillary Mucinous Neoplasms of the Pancreas

  2011cited by this paper
• Cystic precursors to invasive pancreatic cancer

  2011cited by this paper
• Intraductal papillary mucinous neoplasia (IPMN) of the pancreas: its diagnosis, treatment, and prognosis.

  2011cited by this paper
• Diagnostic Performance of Cyst Fluid Carcinoembryonic Antigen and Amylase in Histologically Confirmed Pancreatic Cysts

  2011cited by this paper
• Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas

  2011cited by this paper
• Cyst Fluid Carcinoembryonic Antigen Is an Accurate Diagnostic Marker of Pancreatic Mucinous Cysts

  2011cited by this paper
• Presence of Pancreatic Intraepithelial Neoplasia in the Pancreatic Transection Margin does not Influence Outcome in Patients with R0 Resected Pancreatic Cancer

  2011cited by this paper
• Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypes

  2011cited by this paper
• Molecular characteristics and biological behaviours of the oncocytic and pancreatobiliary subtypes of intraductal papillary mucinous neoplasms

  2011cited by this paper
• Prognostic relevance of pathologic subtypes and minimal invasion in intraductal papillary mucinous neoplasms of the pancreas

  2011cited by this paper
• Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development

  2011cited by this paper
• Invasive carcinoma derived from the nonintestinal type intraductal papillary mucinous neoplasm of the pancreas has a poorer prognosis than that derived from the intestinal type.

  2010cited by this paper
• Pancreatic Cyst Fluid and Serum Mucin Levels Predict Dysplasia in Intraductal Papillary Mucinous Neoplasms of the Pancreas

  2010cited by this paper
• WHO Classification of Tumours of the Digestive System

  2010cited by this paper
• Zystische Tumoren des Pankreas

  2010cited by this paper
• Prognostic relevance of morphological types of intraductal papillary mucinous neoplasms of the pancreas

  2010cited by this paper
• Preferential Expression of MUC6 in Oncocytic and Pancreatobiliary Types of Intraductal Papillary Neoplasms Highlights a Pyloropancreatic Pathway, Distinct From the Intestinal Pathway, in Pancreatic Carcinogenesis

  2010cited by this paper
• Intraductal papillary mucinous tumors of the pancreas: biology, diagnosis, and treatment.

  2010cited by this paper
• Histopathologic Basis for the Favorable Survival after Resection of Intraductal Papillary Mucinous Neoplasm-Associated Invasive Adenocarcinoma of the Pancreas

  2010cited by this paper
• Intraductal papillary mucinous neoplasms of the pancreas with multifocal involvement of branch ducts.

  2009cited by this paper
• Characterizing DNA methylation patterns in pancreatic cancer genome

  2009cited by this paper
• Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients

  2009cited by this paper
• Global Genomic Analysis of Intraductal Papillary Mucinous Neoplasms of the Pancreas Reveals Significant Molecular Differences Compared to Ductal Adenocarcinoma

  2009cited by this paper
• CpG island methylation profile of pancreatic intraepithelial neoplasia

  2008cited by this paper
• Development of ductal carcinoma of the pancreas during follow-up of branch duct intraductal papillary mucinous neoplasm of the pancreas

  2008cited by this paper
• Precursor lesions of pancreatic cancer.

  2008cited by this paper
• Outcome of Invasive and Noninvasive Intraductal Papillary-Mucinous Neoplasms of the Pancreas (IPMN): A 10-year Experience

  2008cited by this paper
• Morphogenesis of pancreatic cancer: role of pancreatic intraepithelial neoplasia (PanINs)

  2008cited by this paper
• Postoperative Adjuvant Chemotherapy Improves Survival after Surgical Resection for Pancreatic Carcinoma

  2008cited by this paper
• Cytological and Cyst Fluid Analysis of Small (≤3 cm) Branch Duct Intraductal Papillary Mucinous Neoplasms Adds Value to Patient Management Decisions

  2008cited by this paper
• Mucinous Cystic Neoplasm of the Pancreas is Not an Aggressive Entity: Lessons From 163 Resected Patients

  2008cited by this paper
• Intraductal Papillary Mucinous Neoplasms of the Pancreas: Clinicopathologic Characteristics and Long-Term Follow-Up After Resection

  2008cited by this paper
• Adjuvant Chemotherapy With Gemcitabine vs Observation in Patients Undergoing Curative-Intent Resection of Pancreatic Cancer: A Randomized Controlled Trial

  2008cited by this paper
• Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis.

  2007cited by this paper
• Mucin expression profile in pancreatic cancer and the precursor lesions.

  2007cited by this paper
• Identifying molecular markers for the early detection of pancreatic neoplasia.

  2007cited by this paper
• BRAF and KRAS gene mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/IPMC) of the pancreas.

  2007cited by this paper
• Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial.

  2007cited by this paper
• Molecular pathogenesis of pancreatic cancer.

  2006cited by this paper
• Multifocal Neoplastic Precursor Lesions Associated With Lobular Atrophy of the Pancreas in Patients Having a Strong Family History of Pancreatic Cancer

  2006cited by this paper
• 1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience

  2006cited by this paper
• Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study

  2005cited by this paper
• Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a meta-analysis.

  2005cited by this paper
• Pathologically and Biologically Distinct Types of Epithelium in Intraductal Papillary Mucinous Neoplasms: Delineation of an “Intestinal” Pathway of Carcinogenesis in the Pancreas

  2004cited by this paper
• An Illustrated Consensus on the Classification of Pancreatic Intraepithelial Neoplasia and Intraductal Papillary Mucinous Neoplasms

  2004cited by this paper
• Cystic neoplasms of the pancreas.

  2004cited by this paper
• Cystic neoplasms of the pancreas and tumor-like lesions with cystic features: a review of 418 cases and a classification proposal

  2004cited by this paper
• Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.

  2003cited by this paper
• Multicomponent Analysis of the Pancreatic Adenocarcinoma Progression Model Using a Pancreatic Intraepithelial Neoplasia Tissue Microarray

  2003cited by this paper
• Aberrant Hypermethylation of Tumor Suppressor Genes in Pancreatic Endocrine Neoplasms

  2003cited by this paper
• Clinicopathological Correlates of Pancreatic Intraepithelial Neoplasia: A Comparative Analysis of 82 Cases With and 152 Cases Without Pancreatic Ductal Adenocarcinoma

  2003cited by this paper
• Aberrant Expression of MUC3 and MUC4 Membrane-Associated Mucins and Sialyl Lex Antigen in Pancreatic Intraepithelial Neoplasia

  2003cited by this paper
• The Dichotomy in the Preinvasive Neoplasia to Invasive Carcinoma Sequence in the Pancreas: Differential Expression of MUC1 and MUC2 Supports the Existence of Two Separate Pathways of Carcinogenesis

  2002cited by this paper
• Molecular pathogenesis of pancreatic cancer.

  2002cited by this paper
• MUC4 expression increases progressively in pancreatic intraepithelial neoplasia.

  2002cited by this paper
• Study of recurrence after surgical resection of intraductal papillary mucinous neoplasm of the pancreas.

  2002cited by this paper
• Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas.

  2002cited by this paper
• The Immunohistochemical Mucin Expression Pattern Distinguishes Different Types of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Determines Their Relationship to Mucinous Noncystic Carcinoma and Ductal Adenocarcinoma

  2001cited by this paper
• Pancreatic Intraepithelial Neoplasia: A New Nomenclature and Classification System for Pancreatic Duct Lesions

  2001cited by this paper
• Dpc4 Protein in Mucinous Cystic Neoplasms of the Pancreas: Frequent Loss of Expression in Invasive Carcinomas Suggests a Role in Genetic Progression

  2000cited by this paper
• Cystic neoplasms of the pancreas

  2000cited by this paper
• TGFbeta signaling in growth control, cancer, and heritable disorders.

  2000cited by this paper
• Mucinous cystic tumors of the pancreas: clinicopathological features, prognosis, and relationship to other mucinous cystic tumors.

  1999cited by this paper
• Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: Its relationship with the biological behavior of the tumor

  1999cited by this paper
• Sequential accumulation of K-ras mutations and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy.

  1999cited by this paper
• Progression of pancreatic intraductal neoplasias to infiltrating adenocarcinoma of the pancreas.

  1998cited by this paper
• Histological Typing of Tumours of the Exocrine Pancreas

  1996cited by this paper
• DPC4 gene in various tumor types.

  1996cited by this paper
• p53: tumor suppression through control of the cell cycle.

  1994cited by this paper
• Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

  1994cited by this paper
• K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.

  1993cited by this paper
• Cystic tumors of the pancreas.

  1990cited by this paper
• Cancer statistics

  1989cited by this paper
• Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes.

  1988cited by this paper
• Cystic tumors of the pancreas.

  1987cited by this paper

• Cystic lesions and their role in pancreatic cancer risk stratification.

  2026cites this paper
• The complex interplay between diabetes mellitus and pancreatic carcinogenesis: deciphering multifactorial mechanisms and identifying emerging therapeutic vulnerabilities

  2025influential citation
• Ex vivo spectroscopic characterisation of the biological activity of pancreatic cyst fluid.

  2025cites this paper
• Phenotypic heterogeneity and tumor immune microenvironment directed therapeutic strategies in pancreatic ductal adenocarcinoma

  2025cites this paper
• Genomic alterations in pancreatic cystic neoplasms: from molecular characterization to precision clinical management

  2025cites this paper
• Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development

  2025cites this paper
• Clinical and molecular features of resected early onset pancreatic ductal adenocarcinoma: insights from the NCDB and cBioPortal.

  2025cites this paper
• Frozen Section Studies of Gastrointestinal and Hepatobiliary Systems: A Review Article

  2025cites this paper
• Preclinical Fluorescence-Guided Imaging Leveraging Surrounding Sentinel Tumor Microenvironment Identifies High-Risk Premalignant Pancreatic Lesions.

  2025cites this paper
• MTAP in small biopsy samples of pancreatic lesions: a potential diagnostic biomarker. Immunohistochemical, fluorescence in situ hybridization and molecular analysis

  2025cites this paper
• Current paradigm and futuristic vision on new-onset diabetes and pancreatic cancer research

  2025cites this paper
• Proteomics in pancreatic cancer

  2025cites this paper
• The multifaceted roles of mucins family in lung cancer: from prognostic biomarkers to promising targets

  2025cites this paper
• A Comprehensive Review on Revolutionizing Pancreatic Cancer Treatment: Liposomal Innovations

  2025cites this paper
• Three-dimensional assessments are necessary to determine the true, spatially resolved composition of tissues

  2025cites this paper
• Opportunities to Avoid Invasive Cancer by Diagnosis and Interception of Preneoplastic Lesions and Cancer Risk Conditions.

  2025cites this paper
• Proximogram - A multi-omics network-based framework to capture tissue heterogeneity integrating single-cell omics and spatial profiling

  2024cites this paper
• Coexisting mechanisms of luminogenesis in pancreatic cancer-derived organoids

  2024cites this paper
• Artificial Intelligence in Pancreatic Image Analysis: A Review

  2024cites this paper
• Clinical Perspectives on the Histomolecular Features of the Pancreatic Precursor Lesions: A Narrative Review

  2024cites this paper
• A mucus production programme promotes classical pancreatic ductal adenocarcinoma

  2024cites this paper
• Notable Histologic Findings in a "Normal" Cohort.

  2024cites this paper
• Biomarkers in Cancer Screening: Promises and Challenges in Cancer Early Detection.

  2024cites this paper
• CT findings and clinical effects of high grade pancreatic intraepithelial neoplasia in patients with intraductal papillary mucinous neoplasms.

  2024cites this paper
• Role of Hippo pathway dysregulation from gastrointestinal premalignant lesions to cancer

  2024cites this paper
• Selective epigenetic alterations in RNF43 in pancreatic exocrine cells from high-fat-diet-induced obese mice; implications for pancreatic cancer

  2024cites this paper
• Overcoming therapy resistance in pancreatic cancer: New insights and future directions.

  2024cites this paper
• TRIM-endous functional network of tripartite motif 29 (TRIM29) in cancer progression and beyond

  2024cites this paper
• PanIN and CAF transitions in pancreatic carcinogenesis revealed with spatial data integration.

  2024cites this paper
• Concurrent Invasive Ductal Carcinoma and Pancreatic Intraepithelial Neoplasia in Duodenal Heterotopic Pancreas: A Case Report.

  2024influential citation
• Molecular Pathway and Immune Profile Analysis of IPMN-Derived Versus PanIN-Derived Pancreatic Ductal Adenocarcinomas

  2024cites this paper
• Exploring the therapeutic potential of focal adhesion kinase inhibition in overcoming chemoresistance in pancreatic ductal adenocarcinoma.

  2024cites this paper
• PanIN or IPMN? Redefining Lesion Size in 3 Dimensions

  2024cites this paper
• Circulating tumor DNA in unresectable pancreatic cancer is a strong predictor of first-line treatment efficacy: The KRASCIPANC prospective study.

  2023cites this paper
• Genetic features of pathogenesis in pancreatic adenocarcinomas

  2023cites this paper
• Three-dimensional analysis of human pancreatic cancer specimens by phase-contrast based X-ray tomography – the next dimension of diagnosis

  2023influential citation
• Farnesoid X receptor activation inhibits pancreatic carcinogenesis.

  2023cites this paper
• Overcoming the Fibrotic Fortress in Pancreatic Ductal Adenocarcinoma: Challenges and Opportunities

  2023cites this paper
• Targeted therapy for pancreatic ductal adenocarcinoma: Mechanisms and clinical study

  2023cites this paper
• Expression patterns of claudins in cancer

  2023cites this paper
• A novel machine learning algorithm selects proteome signature to specifically identify cancer exosomes

  2023cites this paper
• Microbiome and MicroRNA or Long Non-Coding RNA—Two Modern Approaches to Understanding Pancreatic Ductal Adenocarcinoma

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• The Dual Role of Necroptosis in Pancreatic Ductal Adenocarcinoma

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• Understanding the risk of recurrence after resection of intraductal papillary mucinous neoplasm-associated adenocarcinoma: insights from a large multicenter study

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• Modeling Obesity-Driven Pancreatic Carcinogenesis—A Review of Current In Vivo and In Vitro Models of Obesity and Pancreatic Carcinogenesis

  2022cites this paper
• Clinical and Molecular Attributes and Evaluation of Pancreatic Cystic Neoplasm.

  2022cites this paper
• Immunity and Pancreatic Cancer

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• Preneoplastic Lesions in Surgical Specimens Do Not Worsen the Prognosis of Patients Who Underwent Surgery for Pancreatic Adenocarcinoma: Post-Hoc Analysis of the PRODIGE 24-CCTG PA 6 Trial

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• Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosis

  2022cites this paper
• Extracellular Vesicle-Based Multianalyte Liquid Biopsy as a Diagnostic for Cancer.

  2022cites this paper
• Overcoming Immunotherapeutic Resistance in PDAC: SIRPα-CD47 blockade.

  2022cites this paper
• Screening of pancreatic cancer: Target population, optimal timing and how?

  2022cites this paper
• Moving towards dawn: KRas signaling and treatment in pancreatic ductal adenocarcinoma.

  2022cites this paper
• Mutant K-Ras-Mediated Oxidative Stress in Pancreatic Cancer

  2022cites this paper
• De novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancer

  2022cites this paper
• Transforming growth factor-β challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells

  2022cites this paper
• The Use of Intraoperative Frozen Sections in Guiding the Extent of Pancreatic Resections for Intraductal Papillary Mucinous Neoplasms

  2022cites this paper
• Blood-Based Diagnosis and Risk Stratification of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasm (IPMN)

  2022cites this paper
• PGC1α-Mediated Metabolic Reprogramming Drives the Stemness of Pancreatic Precursor Lesions

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• S100 Proteins in Pancreatic Cancer: Current Knowledge and Future Perspectives

  2021cites this paper
• Biomarker Risk Score Algorithm and Preoperative Stratification of Patients with Pancreatic Cystic Lesions.

  2021cites this paper
• Pancreatic adenocarcinoma: molecular drivers and the role of targeted therapy

  2021cites this paper
• CGAT: Cell Graph ATtention Network for Grading of Pancreatic Disease Histology Images

  2021cites this paper
• A review of lifestyle and environment risk factors for pancreatic cancer.

  2021cites this paper
• Cystic pancreatic lesions, the endless dilemma

  2021cites this paper
• RNAi-Based Approaches for Pancreatic Cancer Therapy

  2021cites this paper
• REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway

  2021cites this paper
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  2021cites this paper
• REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway

  2021cites this paper
• Polycystic Disease of the Pancreas: a Case Report and Comprehensive Review of the Literature

  2021cites this paper
• Mutant K-Ras Mediated Oxidative Stress in Pancreatic Cancer

  2021cites this paper
• The Durability of EUS-Guided Chemoablation of Mucinous Pancreatic Cysts: A Long-Term Follow-Up of the CHARM trial

  2021cites this paper
• Advances in the Detection of Pancreatic Cancer Through Liquid Biopsy

  2021cites this paper
• Store-Operated Calcium Entry: Shaping the Transcriptional and Epigenetic Landscape in Pancreatic Cancer

  2021cites this paper
• Diagnosis of the pancreatic cancer

  2021cites this paper
• The State-of-the-Art of Phase II/III Clinical Trials for Targeted Pancreatic Cancer Therapies

  2021cites this paper
• Expression of CD117, CK17, CK20, MUC4, villin and mismatch repair deficiency in pancreatic intraductal papillary mucinous neoplasm.

  2020cites this paper
• Of immune checkpoint maladies and remedies: The throwing of jabs in the oncogenic ring of PDAC.

  2020cites this paper
• Loss of Jag1 cooperates with oncogenic Kras to induce pancreatic cystic neoplasms

  2020influential citation
• TSPO-targeted PET and Optical Probes for the Detection and Localization of Premalignant and Malignant Pancreatic Lesions

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  2020cites this paper
• Intraductal Pancreatic Mucinous Neoplasms: A Tumor-Biology Based Approach for Risk Stratification

  2020cites this paper
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  2020cites this paper
• Gynecological and reproductive factors and the risk of pancreatic cancer: A case-control study.

  2020cites this paper
• Secretory Mucin 5AC Promotes Neoplastic Progression by Augmenting KLF4-Mediated Pancreatic Cancer Cell Stemness

  2020cites this paper
• Claudin-18 in Pancreatic Carcinogenesis Ralph-Tobias Daraban

  2020cites this paper
• Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Differential methylation landscape of pancreatic ductal adenocarcinoma and its precancerous lesions.

  2020cites this paper
• Pancreatic cancer screening in patients with presumed branch-duct intraductal papillary mucinous neoplasms

  2019cites this paper
• Pancreatic Cancer Diagnosis and Management: Has the Time Come to Prick the Bubble?

  2019cites this paper
• Statin use is associated to a reduced risk of pancreatic cancer: A meta-analysis.

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• Circulating thrombospondin-2 enhances prediction of malignant intraductal papillary mucinous neoplasm.

  2019cites this paper
• Proteome alterations in pancreatic ductal adenocarcinoma

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• Fecal microbiome signatures of pancreatic cancer patients

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• Nanomedicine for Imaging and Therapy of Pancreatic Adenocarcinoma

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  2019cites this paper