The potential role of podoplanin in tumour invasion

A. Wicki,G. Christofori

Published 2006 in British Journal of Cancer

ABSTRACT

Podoplanin is a small mucin-like transmembrane protein, widely expressed in various specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin-mediated tumour invasion. We compare molecular pathways leading to single and collective cell invasion and discuss novel distinct concepts of tumour cell invasion.

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