Large animal models of fulminant hepatic failure in artificial and bioartificial liver support research.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Biomaterials

• Publication date

  2004-04-01

• Fields of study

  Biology, Medicine, Engineering

• Identifiers
  DOI 10.1016/S0142-9612(03)00509-XPMID 14697863
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Assessment of an extracorporeal liver assist device in anhepatic dogs.

  2008influential reference
• MARS treatment in posthepatectomy liver failure

  2003cited by this paper
• Encephalopathy and Nitrogen Metabolism in Liver Failure

  2003cited by this paper
• The importance of orthotopic liver transplantation in acute hepatic failure

  2002cited by this paper
• Experiences with MARS liver support therapy in liver failure: analysis of 176 patients of the International MARS Registry.

  2002cited by this paper
• Phase I clinical trial with the AMC-bioartificial liver.

  2002cited by this paper
• An Experimental Large Animal Model for the Assessment of Bioartificial Liver Support Systems in Fulminant Hepatic Failure

  2002influential reference
• Etiology and outcome of acute liver failure: experience from a liver transplantation centre in Montreal.

  2002cited by this paper
• Emerging indications for MARS dialysis.

  2002cited by this paper
• Preclinical evaluation of the Excorp Medical, Inc, Bioartificial Liver Support System.

  2002influential reference
• A Method to assess Biochemical Activity of Liver Cells during Clinical Application of Extracorporeal Hybrid Liver Support

  2002cited by this paper
• The molecular adsorbents recycling system as a liver support system based on albumin dialysis: a summary of preclinical investigations, prospective, randomized, controlled clinical trial, and clinical experience from 19 centers.

  2002cited by this paper
• Phase I Clinical Trial with the AMC-Bioartificial Liver

  2002cited by this paper
• Early experiences with a porcine hepatocyte-based bioartificial liver in acute hepatic failure patients.

  2002cited by this paper
• Development of a Hybrid Artificial Liver Using Polyurethane Foam / Hepatocyte Spheroid Culture in a Preclinical Pig Experiment

  2002cited by this paper
• Haemodynamic changes in ischaemic vs. anhepatic pig experimental model of acute liver failure.

  2002cited by this paper
• Early Experiences with a Porcine Hepatocyte-based Bioartificial Liver in Acute Hepatic Failure Patients

  2002cited by this paper
• ASSESSMENT OF THE AMC-BIOARTIFICIAL LIVER IN THE ANHEPATIC PIG1

  2002cited by this paper
• Extracorporeal blood detoxification by sorbents in treatment of hepatic encephalopathy.

  2002cited by this paper
• Intracranial pressure, brain PCO2, PO2, and pH during hypo- and hyperventilation at constant mean airway pressure in pigs

  2001cited by this paper
• Experimental research on TECA-I bioartificial liver support system to treat canines with acute liver failure.

  2001influential reference
• Animal models of fulminant hepatic failure: need to test liver support devices.

  2001cited by this paper
• Safety Observations in Phase I Clinical Evaluation of the Excorp Medical Bioartificial Liver Support System after the First Four Patients

  2001cited by this paper
• Bioartificial liver treatment prolongs survival and lowers intracranial pressure in pigs with fulminant hepatic failure.

  2001cited by this paper
• Large animal models for testing bioartificial liver support systems.

  2001cited by this paper
• In Vivo Estimation of Bioartificial Liver with Recombinant HepG2 Cells Using Pigs with Ischemic Liver Failure

  2001cited by this paper
• TECA hybrid artificial liver support system in treatment of acute liver failure.

  2001cited by this paper
• Acute liver failure.

  2001cited by this paper
• Severe hepatitis treated with an artificial liver support system

  2001cited by this paper
• N-acetylcysteine increases cerebral perfusion pressure in pigs with fulminant hepatic failure

  2001cited by this paper
• Acute liver failure: Clinical features, outcome analysis, and applicability of prognostic criteria

  2000cited by this paper
• Temporary neurological improvement in a patient with acute or chronic liver failure treated with a bioartificial liver device

  2000cited by this paper
• Animal models of acute hepatic failure

  2000influential reference
• Animal models of fulminant hepatic failure: A critical evaluation

  2000influential reference
• An improved model of acute liver failure based on transient ischemia of the liver.

  2000influential reference
• Monitoring and treatment of intracranial hypertension

  2000cited by this paper
• A reversible model of acute hepatic failure by temporary hepatic ischemia in the pig.

  2000influential reference
• Normalised intrinsic mortality risk in liver transplantation: European Liver Transplant Registry study.

  2000cited by this paper
• A novel stable reproducible model of hepatic failure in canines.

  2000influential reference
• Liver bridging techniques in the treatment of acute liver failure.

  2000cited by this paper
• Postoperative liver failure after major hepatic resection for hepatocellular carcinoma in the modern era with special reference to remnant liver volume.

  1999cited by this paper
• Moderate hypothermia for uncontrolled intracranial hypertension in acute liver failure.

  1999cited by this paper
• Rescue hepatectomy for initial graft non-function after liver transplantation.

  1999cited by this paper
• Long-term treatment of patients with acute exacerbation of chronic liver failure by albumin dialysis.

  1999cited by this paper
• Cerebral herniation in patients with acute E liver failure is correlated with arterial ammonia concentration

  1999cited by this paper
• Oxford Textbook of Clinical Hepatology

  1999cited by this paper
• An improved model of galactosamine-induced fulminant hepatic failure in the pig.

  1999cited by this paper
• Significantly Improved Survival Time in Pigs with Complete Liver Ischemia Treated with a Novel Bioartificial Liver

  1999influential reference
• A new technique for total hepatectomy in the pig for testing liver support devices.

  1999cited by this paper
• Risk of major liver resection in patients with underlying chronic liver disease: a reappraisal.

  1999cited by this paper
• Renal failure in acute liver failure.

  1999cited by this paper
• Review article: the management of acute liver failure.

  1998cited by this paper
• The management of acute liver failure

  1998cited by this paper
• Galactosamine‐induced fulminant hepatic necrosis in unanesthetized canines

  1997cited by this paper
• Effect of a Hybrid Liver Support System on Cardiopulmonary Function in Healthy Pigs

  1997influential reference
• Behavioral and physiological sex differences observed in an animal model of fulminant hepatic encephalopathy in the rat.

  1997cited by this paper
• Clinical experience with a bioartificial liver in the treatment of severe liver failure. A phase I clinical trial.

  1997cited by this paper
• Pilot‐controlled trial of the extracorporeal liver assist device in acute liver failure

  1996cited by this paper
• Extracorporeal auxiliary xenoperfusion: animal model of support in fulminant liver failure.

  1996cited by this paper
• Laboratory animal anaesthesia

  1996cited by this paper
• An anesthetized model of lethal canine galactosamine fulminant hepatic failure

  1995influential reference
• Liver transplantation for fulminant hepatic failure: North American experience.

  1995cited by this paper
• Hybrid liver support system in a short term application on hepatectomized pigs

  1994influential reference
• Spontaneous urinary calculus in young LEW rats caused by Corynebacterium renale.

  1994cited by this paper
• Total hepatectomy for acute liver failure: don't take out my liver!

  1994cited by this paper
• Effects of total hepatectomy: studies in a porcine model.

  1994cited by this paper
• Total Hepatectomy and Liver Transplantation as Two‐stage Procedure

  1993cited by this paper
• Development of a bioartificial liver: Properties and function of a hollow‐fiber module inoculated with liver cells

  1993influential reference
• Liver transplantation for fulminant hepatic failure.

  1993cited by this paper
• Intracranial pressure monitoring and liver transplantation for fulminant hepatic failure

  1992cited by this paper
• An improved model of acetaminophen‐induced fulminant hepatic failure in dogs

  1992cited by this paper
• Morbidity and mortality after surgical resection of liver tumors. Analysis of 229 cases.

  1992cited by this paper
• A new surgical model of acute liver failure in the pig: experimental procedure and analysis of liver injury.

  1991influential reference
• A totally failing liver may be more harmful than no liver at all: three cases of total hepatic devascularization in preparation for emergency liver transplantation.

  1991cited by this paper
• Fulminant hepatic failure. Clinical features, etiology, epidemiology, and current management.

  1991cited by this paper
• Animal models of fulminant hepatic failure

  1991influential reference
• Management of severe hepatic trauma by two-stage total hepatectomy and subsequent liver transplantation.

  1991cited by this paper
• Fulminant hepatic failure

  1991cited by this paper
• Fulminant Hepatic Failure and Orthotopic Liver Transplantation

  1989cited by this paper
• A dog model for acetaminophen-induced fulminant hepatic failure.

  1989cited by this paper
• Partial hepatectomy and liver regeneration in pigs--the response to different resection sizes.

  1988cited by this paper
• Total hepatectomy as temporary approach to acute hepatic or primary graft failure.

  1988cited by this paper
• A reproducible model of acute hepatic failure by transient ischemia in the pig.

  1987cited by this paper
• A predictable pathophysiological model of porcine hepatic failure.

  1986cited by this paper
• Fulminant and Subfulminant Liver Failure: Definitions and Causes

  1986cited by this paper
• The role of protein metabolism in 204 liver cirrhotics with and without hepatic encephalopathy. I. Clinical and general biochemical findings.

  1986cited by this paper
• A reproducible large animal model of acute hepatic failure.

  1984cited by this paper
• Plasma amino acid patterns in experimental acute hepatic failure: comparison between hepatectomy and liver devascularization in pigs.

  1981cited by this paper
• The hepatic coma syndromes and lactulose

  1980cited by this paper
• Intracranial pressure in pigs with surgically induced acute liver failure.

  1979cited by this paper
• Experimental liver failure. A comparison between hepatectomy and hepatic devascularization in the pig.

  1977influential reference
• [Animal model for the study of the anhepatic state].

  1977cited by this paper
• An animal model of fulminant hepatic failure: a feasibility study.

  1976cited by this paper
• A dog model of fulminant hepatic failure produced by paracetamol administration.

  1975cited by this paper
• Liver function in the pig. Total hepatic and portal flow values in vivo.

  1974cited by this paper
• Effects of haemoperfusion through charcoal or XAD-2 resin on an animal model of fulminant liver failure

  1974cited by this paper
• [Experimental hepatic coma due to acute ischemic necrosis of the liver in swine].

  1972cited by this paper
• A new method for one-stage hepatectomy for dogs.

  1959cited by this paper
• Hepatic coma following ischemia of the liver.

  1953cited by this paper
• Hepatic coma following ischemia of the liver.

  1953cited by this paper

• Genetic engineering drives the breakthrough of pig models in liver disease research

  2024cites this paper
• A breakthrough trial of an artificial liver without systemic heparinization in hyperbilirubinemia beagle models

  2022cites this paper
• 2021 ISHEN guidelines on animal models of hepatic encephalopathy

  2021cites this paper
• A novel, simplified, and reproducible porcine model of acute ischemic liver failure with portal vein preservation

  2021cites this paper
• Hepatic tissue engineering

  2020cites this paper
• Inducing Acute Liver Injury in Rats via Carbon Tetrachloride (CCl4) Exposure Through an Orogastric Tube.

  2020cites this paper
• Development of a 3D porous chitosan/gelatin liver scaffold for a bioartificial liver device.

  2020cites this paper
• Injectable hydrogels based on glycyrrhizin, alginate, and calcium for three-dimensional cell culture in liver tissue engineering.

  2018cites this paper
• Establishment of a Novel Simplified Surgical Model of Acute Liver Failure in the Cynomolgus Monkey

  2016cites this paper
• Expression of Inflammatory and Regenerative Genes in a Model of Liver Ischemia/Reperfusion and Partial Hepatectomy

  2016cites this paper
• Tissue Engineering of Organ Systems

  2014cites this paper
• Hybrid bioartificial liver support in cynomolgus monkeys with D-galactosamine-induced acute liver failure.

  2014cites this paper
• Liver Regeneration: The Bioengineering Approach

  2014cites this paper
• Cell-free DNA as a potential marker to predict carbon tetrachloride-induced acute liver injury in rats

  2013cites this paper
• Study of porcine hepatocyte-entrapped bioartificial liver in surgery-induced fulminant hepatic failure rabbits

  2013cites this paper
• Regenerative Therapies for Digestive, Respiratory and Urinary Tissues

  2012cites this paper
• A Macaca mulatta model of fulminant hepatic failure.

  2012cites this paper
• Neuromonitoring in a porcine model of acute hepatic failure

  2011cites this paper
• Liver Regeneration and Tissue Engineering

  2011cites this paper
• Development of a porcine model of post-hepatectomy liver failure.

  2011cites this paper
• Early myocardial injury is an integral component of experimental acute liver failure – a study in two porcine models

  2011cites this paper
• Bio-artificial liver support system : an evaluation of models used in demonstrating or improving metabolic and clinical efficacy

  2010influential citation
• Gene therapy for acute liver failure.

  2010cites this paper
• A Model of Ischemic Isolated Acute Liver Failure in Pigs: Standardizing Monitoring and Treatment

  2010cites this paper
• Treatment with bioartificial liver improves lung injury in a swine model of partial hepatectomy and ischemia/reperfusion.

  2010cites this paper
• Preclinical characterization of primary porcine hepatocytes in a clinically relevant flat membrane bioreactor.

  2010cites this paper
• The Preparation of Functionalized Crosslinked Macroporous Chitosan Microspheres and their Adsorption Properties for Bilirubin

  2010cites this paper
• [Hepatic tissue engineering].

  2010cites this paper
• Treatment with Bioartificial Liver Improves Lung Injury in a Swine Model of Partial Hepatectomy and Ischemia/Reperfusion

  2010cites this paper
• An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure.

  2009cites this paper
• Non-toxicity of IV Injected Perfluorocarbon Oxygen Carrier in an Animal Model of Liver Regeneration Following Surgical Injury

  2009cites this paper
• STAT3 Mediates Protection From Liver Inflammation After Partial Hepatectomy

  2009cites this paper
• Chapter 21 – Tissue engineering of organ systems

  2008cites this paper
• Bio-artificial liver devices--tentative, but promising progress.

  2008cites this paper
• Laparoscopy-Assisted Creation of a Liver Failure Model in Pigs

  2008cites this paper
• Towards application of a human liver cell line for use in the AMC bioartificial liver

  2007cites this paper
• Method of intracranial pressure monitoring and cerebrospinal fluid sampling in swine

  2007cites this paper
• Evaluation of liver support systems for preclinical testing by animal trials.

  2006cites this paper
• Evaluation of a bioartificial liver based on a nonwoven fabric bioreactor with porcine hepatocytes in pigs.

  2006cites this paper
• Standardization criteria for an ischemic surgical model of acute hepatic failure in pigs.

  2006influential citation
• Selective elimination of hepatic natural killer T cells with Concanavalin A improves liver regeneration in mice

  2006cites this paper
• Significant survival prolongation in pigs with fulminant hepatic failure treated with a novel microgravity-based bioartificial liver.

  2006cites this paper
• Regenerative Medicine of Digestive, Respiratory, and Urinary Tissues

  2006cites this paper
• Liver Support Therapy: An Overview of the AMC-Bioartificial Liver Research

  2005cites this paper
• Bioartificial liver systems: current status and future perspective.

  2005cites this paper
• Extra‐hepatic factor VIII expression in porcine fulminant hepatic failure

  2005cites this paper
• Acute Liver Failure: A Critical Appraisal of Available Animal Models

  2005cites this paper
• Effect on function of rat hepatocytes cultured with bone marrow cells

  2004cites this paper