Transcriptional Regulation of the BCL-X Gene by NF-κB Is an Element of Hypoxic Responses in the Rat Brain

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Neurochemical Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1023/A:1010987220034
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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• Modulation of cell death by Bcl-XL through caspase interaction.

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• Regulation of an essential innate immune response by the p50 subunit of NF-kappaB.

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• Neurologic outcome of prematurity.

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• Temporal and anatomical variations of brain water apparent diffusion coefficient in perinatal cerebral hypoxic‐ischemic injury: Relationships to cerebral energy metabolism

  1998cited by this paper
• Death receptors: signaling and modulation.

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• Bcl-x(l) Bax interaction after transient global ischemia.

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• Mechanisms of cerebral injury in perinatal asphyxia and strategies for prevention.

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• Control of apoptosis by proteases.

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• Bcl-Xshort is elevated following severe global ischemia in rat brains.

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• Redox regulation of NF-kappa B activation.

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