Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells

Double fluorescence studies indicated that most mature lymphocytes of 11-52-wk-old mice possess both IgM and IgD-like surface immunoglobulins, while spleen cells from neonatal mice possess surface IgM only. These molecules cap independently with class-specific antisera, but co-cap when capping is induced by antigen. It is proposed that the two heavy chains on individual lymphocytes possess similar or identical antigen-combining sites.

• Publication year

  1976

• Venue

  Journal of Experimental Medicine

• Publication date

  1976-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/JEM.144.3.852PMID 822118PMCID 2190395
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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