Meiotic recombination hotspots: shaping the genome and insights into hypervariable minisatellite DNA change.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Current Topics in Developmental Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0070-2153(08)60171-4PMID 9352183PMCID PMC3151733
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cold Spring Harbor Laboratory.

  2014cited by this paper
• A high recombination frequency within the chicken major histocompatibility (B) complex.

  2009cited by this paper
• Hotspots of meiotic recombination in the mouse major histocompatibility complex

  2006cited by this paper
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  2004cited by this paper
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• Recombination in the class III region of the mouse major histocompatibility complex

  2004cited by this paper
• Multiple sites of crossing over within the Eb recombinational hotspot in the mouse

  2004cited by this paper
• Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe.

  1997cited by this paper
• Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae.

  1997cited by this paper
• An atypical topoisomerase II from archaea with implications for meiotic recombination

  1997influential reference
• The meiotic recombination hot spot created by the single-base substitution ade6-M26 results in remodeling of chromatin structure in fission yeast.

  1997cited by this paper
• Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family.

  1997influential reference
• Molecular analysis of a recombinational hotspot adjacent to Lmp2 gene in the mouse MHC: Fine location and chromatin structure

  1996cited by this paper
• The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.

  1996influential reference
• Mutation rate in the hypervariable VNTR g3 (D7S22) is affected by allele length and a flanking DNA sequence polymorphism near the repeat array.

  1996cited by this paper
• Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast.

  1996influential reference
• Schizosaccharomyces pombe pcr1+ encodes a CREB/ATF protein involved in regulation of gene expression for sexual development

  1996influential reference
• Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae

  1996influential reference
• Double strand breaks at the HIS2 recombination hot spot in Saccharomyces cerevisiae.

  1996cited by this paper
• Meiosis: how could it work?

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• The nucleotide mapping of DNA double‐strand breaks at the CYS3 initiation site of meiotic recombination in Saccharomyces cerevisiae.

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  1995cited by this paper
• Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast.

  1995cited by this paper
• Meiotic recombination hotspots.

  1995influential reference
• Sequence non‐specific double‐strand breaks and interhomolog interactions prior to double‐strand break formation at a meiotic recombination hot spot in yeast.

  1995cited by this paper
• Hotspots of homologous recombination in mouse meiosis.

  1995influential reference
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  1995influential reference
• Is the synaptonemal complex a disjunction machine?

  1995cited by this paper
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  1995influential reference
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  1995cited by this paper
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  1995influential reference
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  1995influential reference
• Factors that affect the location and frequency of meiosis-induced double-strand breaks in Saccharomyces cerevisiae.

  1995influential reference
• Changes in chromatin structure at recombination initiation sites during yeast meiosis.

  1994influential reference
• RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis.

  1994cited by this paper
• Instability of simple sequence repeats in a mammalian cell line.

  1994cited by this paper
• A uniquely high level of recombination at the HLA-B locus.

  1994cited by this paper
• Complex recombination events at the hypermutable minisatellite CEB1 (D2S90).

  1994influential reference
• Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

  1994cited by this paper
• Biochemistry of homologous recombination in Escherichia coli.

  1994cited by this paper
• Meiosis-induced double-strand break sites determined by yeast chromatin structure.

  1994influential reference
• Crossover interference is abolished in the absence of a synaptonemal complex protein.

  1994cited by this paper
• Three additional linkage groups that repress transcription and meiotic recombination in the mating-type region of Schizosaccharomyces pombe.

  1994cited by this paper
• Preferential strand transfer and hybrid DNA formation at the recombination hotspot ade6‐M26 of Schizosaccharomyces pombe.

  1994cited by this paper
• Molecular mechanism of the t(14;18)--a model for lymphoid-specific chromosomal translocations.

  1994cited by this paper
• Region-specific activators of meiotic recombination in Schizosaccharomyces pombe.

  1994cited by this paper
• Minisatellite DNA-binding proteins in mouse brain, liver, and kidney.

  1994cited by this paper
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• Transient, meiosis-induced expression of the rec6 and rec12 genes of Schizosaccharomyces pombe.

  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
• M26 recombinational hotspot and physical conversion tract analysis in the ade6 gene of Schizosaccharomyces pombe.

  1994influential reference
• Polarity of meiotic gene conversion in fungi: Contrasting views

  1994cited by this paper
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• Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism

  1994cited by this paper
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• A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity.

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• A tetranucleotide repeat mouse minisatellite displaying substantial somatic instability during early preimplantation development.

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• Minisatellite mutation and recombination

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• Allelic variation of reporter gene activation by the HRAS1 minisatellite.

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• Genomic polymorphism, recombination, and linkage disequilibrium in human major histocompatibility complex-encoded antigen-processing genes.

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• Chromosome size-dependent control of meiotic recombination.

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• The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiae.

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• Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein.

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• A DNA exonuclease induced during meiosis of Schizosaccharomyces pombe.

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• Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae.

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• DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression.

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• swi6, a gene required for mating-type switching, prohibits meiotic recombination in the mat2-mat3 "cold spot" of fission yeast.

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• Conjugational recombination in E. coli: myths and mechanisms.

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