CD8+-Cell-Mediated Suppression of Virulent Simian Immunodeficiency Virus during Tenofovir Treatment

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Virology

• Publication date

  2004-05-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.78.10.5324-5337.2004PMID 15113912PMCID PMC400346
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Number of CD4+ and CD8+ T-cell CDR3 clonotypes expanding during acute infection of macaques with simian immunodeficiency virus.

  2004cited by this paper
• One step forwards, one step backwards, one step forwards: the impact of EU policy on gender relations in Central and Eastern Europe

  2004cited by this paper
• Biological Effects of Short-Term or Prolonged Administration of 9-[2-(Phosphonomethoxy)Propyl]Adenine (Tenofovir) to Newborn and Infant Rhesus Macaques

  2004cited by this paper
• The Clinical Benefits of Tenofovir for Simian Immunodeficiency Virus–Infected Macaques Are Larger Than Predicted by its Effects on Standard Viral and Immunologic Parameters

  2004cited by this paper
• Highly Uneven Distribution of Tenofovir-Selected Simian Immunodeficiency Virus in Different Anatomical Sites of Rhesus Macaques

  2004cited by this paper
• CD8+ T-Cell Numbers Predict the Response to Antiviral Therapy in HIV-1-Infected Children

  2003cited by this paper
• Extended Treatment With Tenofovir Disoproxil Fumarate in Treatment‐Experienced HIV‐1‐Infected Patients: Genotypic, Phenotypic, and Rebound Analyses

  2003cited by this paper
• CD8 T Cells Remember with a Little Help

  2003cited by this paper
• A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo

  2003cited by this paper
• Comprehensive Epitope Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses Directed against the Entire Expressed HIV-1 Genome Demonstrate Broadly Directed Responses, but No Correlation to Viral Load

  2003cited by this paper
• Detection of antigen-specific T cell interferon gamma expression by ELISPOT and cytokine flow cytometry assays in rhesus macaques.

  2003cited by this paper
• Reversion of the M184V Mutation in Simian Immunodeficiency Virus Reverse Transcriptase Is Selected by Tenofovir, Even in the Presence of Lamivudine

  2003cited by this paper
• Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N6-substituted adenines, and 2,6-diaminopurines.

  2003cited by this paper
• Immunization of Newborn Rhesus Macaques with Simian Immunodeficiency Virus (SIV) Vaccines Prolongs Survival after Oral Challenge with Virulent SIVmac251

  2003cited by this paper
• Identification and Simian Immunodeficiency Virus Infection of CD1d-Restricted Macaque Natural Killer T Cells

  2003cited by this paper
• Role of CD8+ Lymphocytes in Control and Clearance of Measles Virus Infection of Rhesus Monkeys

  2003cited by this paper
• CD8+ T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection

  2003cited by this paper
• Determining the relative efficacy of highly active antiretroviral therapy.

  2003cited by this paper
• Effect of Humoral Immune Responses on Controlling Viremia during Primary Infection of Rhesus Monkeys with Simian Immunodeficiency Virus

  2003cited by this paper
• Therapeutic dendritic-cell vaccine for simian AIDS

  2003cited by this paper
• Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques,

  2003cited by this paper
• Administration of Recombinant Rhesus Interleukin-12 during Acute Simian Immunodeficiency Virus (SIV) Infection Leads to Decreased Viral Loads Associated with Prolonged Survival in SIVmac251-Infected Rhesus Macaques

  2002cited by this paper
• Residual Viral Replication during Antiretroviral Therapy Boosts Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses in Subjects Treated Early after Infection

  2002cited by this paper
• Metabolic activation of nucleoside and nucleotide reverse transcriptase inhibitors in dendritic and Langerhans cells

  2002cited by this paper
• Expansion of pre-existing, lymph node-localized CD8+ T cells during supervised treatment interruptions in chronic HIV-1 infection.

  2002cited by this paper
• AIDS vaccines: One step forwards, one step back

  2002cited by this paper
• Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

  2002cited by this paper
• HIV-1 superinfection despite broad CD8+ T-cell responses containing replication of the primary virus

  2002cited by this paper
• Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir.

  2002cited by this paper
• Immune intervention strategies for HIV-1 infection of humans in the SIV macaque model.

  2002cited by this paper
• Topical administration of low-dose tenofovir disoproxil fumarate to protect infant macaques against multiple oral exposures of low doses of simian immunodeficiency virus.

  2002cited by this paper
• Virulence and Reduced Fitness of Simian Immunodeficiency Virus with the M184V Mutation in Reverse Transcriptase

  2002cited by this paper
• STI and beyond: the prospects of boosting anti-HIV immune responses.

  2002cited by this paper
• AIDS vaccine models: Challenging challenge viruses

  2002cited by this paper
• Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS.

  2002cited by this paper
• Adoptive transfer of simian immunodeficiency virus (SIV) naïve autologous CD4(+) cells to macaques chronically infected with SIV is sufficient to induce long-term nonprogressor status.

  2002cited by this paper
• The critical role of CD4(+) T-cell help in immunity to HIV.

  2002cited by this paper
• Neutralizing antibodies as a potential secondary protective mechanism during chronic SHIV infection in CD8+ T-cell-depleted macaques

  2002cited by this paper
• Live, Attenuated Simian Immunodeficiency Virus SIVmac-M4, with Point Mutations in the Env Transmembrane Protein Intracytoplasmic Domain, Provides Partial Protection from Mucosal Challenge with Pathogenic SIVmac251

  2002cited by this paper
• Activation by 9-(R)-[2-(Phosphonomethoxy)Propyl]Adenine of Chemokine (RANTES, Macrophage Inflammatory Protein 1α) and Cytokine (Tumor Necrosis Factor Alpha, Interleukin-10 [IL-10], IL-1β) Production

  2001cited by this paper
• Antiretroviral Agents Restore Mycobacterium-Specific T-Cell Immune Responses and Facilitate Controlling a Fatal Tuberculosis-Like Disease in Macaques Coinfected with Simian Immunodeficiency Virus andMycobacterium bovis BCG

  2001cited by this paper
• Cellular immune responses to HIV

  2001cited by this paper
• Titration of an SIVmac251 Stock by Vaginal Inoculation of Indian and Chinese Origin Rhesus Macaques: Transmission Efficiency, Viral Loads, and Antibody Responses

  2001cited by this paper
• Role of CD8+ Lymphocytes in Control of Simian Immunodeficiency Virus Infection and Resistance to Rechallenge after Transient Early Antiretroviral Treatment

  2001cited by this paper
• Route of Simian Immunodeficiency Virus Inoculation Determines the Complexity but Not the Identity of Viral Variant Populations That Infect Rhesus Macaques

  2001cited by this paper
• An in Vivo Model for HIV Resistance Development

  2001cited by this paper
• Emergence and Kinetics of Simian Immunodeficiency Virus-Specific CD8+ T Cells in the Intestines of Macaques during Primary Infection

  2001cited by this paper
• Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4+ and CD8+ T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection

  2001cited by this paper
• Enhanced cellular immune response and reduced CD8(+) lymphocyte apoptosis in acutely SIV-infected Rhesus macaques after short-term antiretroviral treatment.

  2001cited by this paper
• Two low doses of tenofovir protect newborn macaques against oral simian immunodeficiency virus infection.

  2001cited by this paper
• Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection.

  2001cited by this paper
• Prophylactic and Therapeutic Benefits of Short-Term 9-[2-(R)-(Phosphonomethoxy)Propyl]Adenine (PMPA) Administration to Newborn Macaques following Oral Inoculation with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA

  2000cited by this paper
• Control of SIV rebound through structured treatment interruptions during early infection.

  2000cited by this paper
• Immune control of HIV-1 after early treatment of acute infection

  2000cited by this paper
• Containment of Simian Immunodeficiency Virus Infection: Cellular Immune Responses and Protection from Rechallenge following Transient Postinoculation Antiretroviral Treatment

  2000cited by this paper
• Cytokine Expression, Natural Killer Cell Activation, and Phenotypic Changes in Lymphoid Cells from Rhesus Macaques during Acute Infection with Pathogenic Simian Immunodeficiency Virus

  2000cited by this paper
• Evaluation of HIV-1 immunogen, an immunologic modifier, administered to patients infected with HIV having 300 to 549 x 10(6)/L CD4 cell counts: A randomized controlled trial.

  2000cited by this paper
• HIV–1 dynamics revisited: biphasic decay by cytotoxic T lymphocyte killing?

  2000influential reference
• Viremia control following antiretroviral treatment and therapeutic immunization during primary SIV251 infection of macaques

  2000cited by this paper
• Lasting effects of transient postinoculation tenofovir [9-R-(2-Phosphonomethoxypropyl)adenine] treatment on SHIV(KU2) infection of rhesus macaques.

  2000cited by this paper
• Antiretroviral Therapy during Primary Immunodeficiency Virus Infection Can Induce Persistent Suppression of Virus Load and Protection from Heterologous Challenge in Rhesus Macaques

  2000cited by this paper
• Efficacy of Postexposure Prophylaxis after Intravaginal Exposure of Pig-Tailed Macaques to a Human-Derived Retrovirus (Human Immunodeficiency Virus Type 2)

  2000cited by this paper
• In Vitro and in Vivo Responses to Interleukin 12 Are Maintained until the Late SIV Infection Stage but Lost during AIDS

  2000cited by this paper
• Slower decline of plasma HIV-1 RNA following highly suppressive antiretroviral therapy in primary compared with chronic infection

  2000cited by this paper
• Post-exposure prophylaxis with highly active antiretroviral therapy could not protect macaques from infection with SIV/HIV chimera.

  2000cited by this paper
• Suppression of Acute Viremia by Short-Term Postexposure Prophylaxis of Simian/Human Immunodeficiency Virus SHIV-RT-Infected Monkeys with a Novel Reverse Transcriptase Inhibitor (GW420867) Allows for Development of Potent Antiviral Immune Responses Resulting in Efficient Containment of Infection

  2000cited by this paper
• Postinoculation PMPA Treatment, but Not Preinoculation Immunomodulatory Therapy, Protects against Development of Acute Disease Induced by the Unique Simian Immunodeficiency Virus SIVsmmPBj

  1999cited by this paper
• Early Short-Term 9-[2-(R)-(Phosphonomethoxy)Propyl]Adenine Treatment Favorably Alters the Subsequent Disease Course in Simian Immunodeficiency Virus-Infected Newborn Rhesus Macaques

  1999cited by this paper
• Association between Virus-Specific Cytotoxic T-Lymphocyte and Helper Responses in Human Immunodeficiency Virus Type 1 Infection

  1999cited by this paper
• Dramatic Rise in Plasma Viremia after CD8+ T Cell Depletion in Simian Immunodeficiency Virus–infected Macaques

  1999cited by this paper
• Rapid and slow progressors differ by a single MHC class I haplotype in a family of MHC-defined rhesus macaques infected with SIV.

  1999cited by this paper
• Simian Immunodeficiency Virus Disease Course Is Predicted by the Extent of Virus Replication during Primary Infection

  1999cited by this paper
• 9-[2-(Phosphonomethoxy)propyl]adenine (PMPA) Therapy Prolongs Survival of Infant Macaques Inoculated with Simian Immunodeficiency Virus with Reduced Susceptibility to PMPA

  1999cited by this paper
• Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes.

  1999cited by this paper
• Emergence of CTL coincides with clearance of virus during primary simian immunodeficiency virus infection in rhesus monkeys.

  1999cited by this paper
• A nonhuman primate model for the selective elimination of CD8+ lymphocytes using a mouse-human chimeric monoclonal antibody.

  1999cited by this paper
• Administration of 9-[2-(Phosphonomethoxy)propyl] adenine (PMPA) for Prevention of Perinatal Simian Immunodeficiency Virus Infection in Rhesus Macaques

  1998cited by this paper
• Interleukin-12: a cytokine at the interface of inflammation and immunity.

  1998cited by this paper
• Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA.

  1998cited by this paper
• The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

  1998cited by this paper
• The role of a stromal cell‐derived factor‐1 chemokine gene variant in the clinical course of HIV‐1 infection

  1998cited by this paper
• Anti-Human Immunodeficiency Virus Activity and Cellular Metabolism of a Potential Prodrug of the Acyclic Nucleoside Phosphonate 9-R-(2-Phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA

  1998cited by this paper
• Administration of Recombinant Human Interleukin 12 to Chronically SIVmac-Infected Rhesus Monkeys

  1998cited by this paper
• Two doses of PMPA protect newborn macaques against oral simian immunodeficiency virus infection

  1998cited by this paper
• Effectiveness of Postinoculation (R)-9-(2-Phosphonylmethoxypropyl)Adenine Treatment for Prevention of Persistent Simian Immunodeficiency Virus SIVmne Infection Depends Critically on Timing of Initiation and Duration of Treatment

  1998cited by this paper
• A high frequency of Mamu-A*01 in the rhesus macaque detected by polymerase chain reaction with sequence-specific primers and direct sequencing.

  1997cited by this paper
• Anti-viral drug treatment: dynamics of resistance in free virus and infected cell populations.

  1997cited by this paper
• A zidovudine-resistant simian immunodeficiency virus mutant with a Q151M mutation in reverse transcriptase causes AIDS in newborn macaques

  1997cited by this paper
• Virus dynamics and drug therapy.

  1997cited by this paper
• Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infection

  1997cited by this paper
• Didanosine but Not High Doses of Hydroxyurea Rescue Pigtail Macaque from a Lethal Dose of SIVsmmpbj14

  1997cited by this paper
• Effects of (R)-9-(2-Phosphonylmethoxypropyl)adenine Monotherapy on Chronic SIV Infection in Macaques

  1997cited by this paper
• Copyright � 1997, American Society for Microbiology Human Immunodeficiency Virus Drug Therapy and Virus Load

  1996cited by this paper
• Persistent Viral Infections

  1996cited by this paper
• Vaccination of pregnant macaques protects newborns against mucosal simian immunodeficiency virus infection.

  1996cited by this paper
• Guide for the Care and Use of Laboratory Animals

  1996cited by this paper
• 9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaques

  1996cited by this paper
• Efficacy of 9-(2-phosphonylmethoxyethyl)adenine treatment against chronic simian immunodeficiency virus infection in macaques.

  1995cited by this paper
• Immediate zidovudine treatment protects simian immunodeficiency virus-infected newborn macaques against rapid onset of AIDS

  1995cited by this paper
• Prevention of SIV Infection in Macaques by (R)-9-(2-Phosphonylmethoxypropyl)adenine

  1995cited by this paper

• Making a Monkey out of Human Immunodeficiency Virus/Simian Immunodeficiency Virus Pathogenesis: Immune Cell Depletion Experiments as a Tool to Understand the Immune Correlates of Protection and Pathogenicity in HIV Infection

  2024cites this paper
• A cross-species comparison of antiretroviral penetration into lymph nodes using novel physiologically based pharmacokinetic models.

  2021cites this paper
• Custommune: a web tool to design personalized and population-targeted vaccine epitopes

  2020cites this paper
• Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected Macaques Selects for Several Patterns of Resistance Mutations with Variable Virological Outcomes

  2018cites this paper
• Emergence of resistance mutations in simian immunodeficiency virus (SIV)-infected rhesus macaques receiving non-suppressive antiretroviral therapy (ART)

  2018cites this paper
• Tackling HIV and AIDS: contributions by non-human primate models

  2017cites this paper
• Tackling HIV and AIDS: contributions by non-human primate models

  2017cites this paper
• Virus Tissue Blood Compartmentalization in Acute Infection of

  2017cites this paper
• Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques

  2017cites this paper
• The Effect of nef-Deleted SIV Administration on Disease Progression in SIVInfected Rhesus Macaques

  2016cites this paper
• CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.

  2016cites this paper
• Characterization of the Drug Resistance Profiles of Integrase Strand Transfer Inhibitors in Simian Immunodeficiency Virus SIVmac239

  2015cites this paper
• Identifying the Conditions Under Which Antibodies Protect Against Infection by Equine Infectious Anemia Virus

  2014cites this paper
• A Vaccine against CCR5 Protects a Subset of Macaques upon Intravaginal Challenge with Simian Immunodeficiency Virus SIVmac251

  2013cites this paper
• Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal

  2012influential citation
• The Use of Nonhuman Primate Models of HIV Infection for the Evaluation of Antiviral Strategies

  2012influential citation
• Compared to Subcutaneous Tenofovir, Oral Tenofovir Disoproxyl Fumarate Administration Preferentially Concentrates the Drug into Gut-Associated Lymphoid Cells in Simian Immunodeficiency Virus-Infected Macaques

  2012cites this paper
• Animal models of HIV transmission through breastfeeding and pediatric HIV infection.

  2012cites this paper
• AIDS Vaccines and Preexposure Prophylaxis: Is Synergy Possible?

  2011cites this paper
• Peripheral blood lymphocyte dynamics and viral kinetics in patients with chronic active hepatitis B virus infection treated by tenofovir.

  2011cites this paper
• Einfluss von Viruslast und viralen Mutationen auf HIV-1 spezifische CD8 T-Zellen

  2011cites this paper
• Control of M184V HIV-1 mutants by CD8 T-cell responses

  2011cites this paper
• Mechanism of protection of live attenuated simian immunodeficiency virus: coevolution of viral and immune responses.

  2010cites this paper
• Experimental depletion of CD8+ cells in acutely SIVagm-Infected African Green Monkeys results in increased viral replication

  2010cites this paper
• Evaluation of antiretrovirals in animal models of HIV infection.

  2010influential citation
• CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells

  2010cites this paper
• Immunogenicity of viral vector, prime-boost SIV vaccine regimens in infant rhesus macaques: attenuated vesicular stomatitis virus (VSV) and modified vaccinia Ankara (MVA) recombinant SIV vaccines compared to live-attenuated SIV.

  2010cites this paper
• Enhanced Antibody Responses Elicited by a CpG Adjuvant Do Not Improve the Protective Effect of an Aldrithiol-2-Inactivated Simian Immunodeficiency Virus Therapeutic AIDS Vaccine

  2009cites this paper
• Chronic Administration of Tenofovir to Rhesus Macaques from Infancy through Adulthood and Pregnancy: Summary of Pharmacokinetics and Biological and Virological Effects

  2008influential citation
• A Therapeutic SIV DNA Vaccine Elicits T-Cell Immune Responses, but No Sustained Control of Viremia in SIVmac239-Infected Rhesus Macaques

  2008cites this paper
• Therapeutic immunization with Modified Vaccinia Virus Ankara (MVA) vaccines in SIV‐infected rhesus monkeys undergoing antiretroviral therapy

  2007cites this paper
• Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection

  2007influential citation
• Evolution of the Virulent Primary Isolate, SIV/DeltaB670, in vivo,Implications for Study Design and Antiviral Therapies

  2007cites this paper
• Virus-specific T cell responses in macaques acutely infected with SHIV(sf162p3).

  2007cites this paper
• Role of CD8+ cells in controlling replication of nonpathogenic simian immunodeficiency virus

  2006cites this paper
• Challenge mac251 against Oral SIV Protection of Neonatal Rhesus Macaques Cellular Cytotoxicity-Mediating IgG in Nonneutralizing Antibody-Dependent Evaluation of Passively Transferred,

  2006cites this paper
• Role of CD8+ cells in controlling replication of nonpathogenic Simian Immunodeficiency Virus SIVmac1A11

  2006cites this paper
• Evaluation of Oral Tenofovir Disoproxil Fumarate and Topical Tenofovir GS-7340 to Protect Infant Macaques Against Repeated Oral Challenges With Virulent Simian Immunodeficiency Virus

  2006influential citation
• Evaluation of Passively Transferred, Nonneutralizing Antibody-Dependent Cellular Cytotoxicity-Mediating IgG in Protection of Neonatal Rhesus Macaques against Oral SIVmac251 Challenge1

  2006cites this paper
• Post-exposure prophylaxis for SIV revisited: Animal model for HIV prevention

  2006influential citation
• Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques

  2006cites this paper
• In Vitro Human Immunodeficiency Virus Type 1 Resistance Selections with Combinations of Tenofovir and Emtricitabine or Abacavir and Lamivudine

  2006cites this paper
• Effects of monotherapy with (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) on the evolution of a primary Simian immunodeficiency virus (SIV) isolate.

  2006cites this paper
• A rapid and sensitive real-time PCR assay for the K65R drug resistance mutation in SIV reverse transcriptase.

  2006cites this paper
• Rhesus Macaque Polyclonal and Monoclonal Antibodies Inhibit Simian Immunodeficiency Virus in the Presence of Human or Autologous Rhesus Effector Cells

  2006influential citation
• Structured Treatment Interruptions with Tenofovir Monotherapy for Simian Immunodeficiency Virus-Infected Newborn Macaques

  2006cites this paper
• SIV Infection of Macaques as a Model for AIDS Drug Studies

  2006cites this paper
• In Vitro Human Immunodeficiency Virus Type 1 Resistance Selections with Combinations of Tenofovir and Emtricitabine or Abacavir and Lamivudine (cid:1)

  2006cites this paper
• Inefficient Cytotoxic T Lymphocyte–Mediated Killing of HIV-1–Infected Cells In Vivo

  2006cites this paper
• In HIV Type 1-Infected Children Cytotoxic T Lymphocyte Responses Are Associated with Greater Reduction of Viremia under Antiretroviral Therapy

  2005cites this paper
• Evaluation of CD 8 + T-cell and antibody responses following transient increased viraemia in rhesus macaques infected with live , attenuated simian immunodeficiency virus

  2005cites this paper
• Antiretroviral drug studies in nonhuman primates: a valid animal model for innovative drug efficacy and pathogenesis experiments.

  2005cites this paper
• Attenuated Poxvirus-Based Simian Immunodeficiency Virus (SIV) Vaccines Given in Infancy Partially Protect Infant and Juvenile Macaques Against Repeated Oral Challenge With Virulent SIV

  2005cites this paper
• Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS.

  2005cites this paper
• Evaluation of CD8+ T-cell and antibody responses following transient increased viraemia in rhesus macaques infected with live, attenuated simian immunodeficiency virus.

  2005cites this paper
• Tenofovir primes rhesus macaque cells in vitro for enhanced interleukin-12 secretion.

  2004cites this paper
• The Clinical Benefits of Tenofovir for Simian Immunodeficiency Virus–Infected Macaques Are Larger Than Predicted by its Effects on Standard Viral and Immunologic Parameters

  2004influential citation
• Biological Effects of Short-Term or Prolonged Administration of 9-[2-(Phosphonomethoxy)Propyl]Adenine (Tenofovir) to Newborn and Infant Rhesus Macaques

  2004cites this paper