A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation

Toxoplasma gondii secretes a novel dense granule protein, GRA24, that traffics from the vacuole to the host cell nucleus where it prolongs p38a activation and correlates with proinflammatory cytokine production.

• Publication year

  2013

• Venue

  Journal of Experimental Medicine

• Publication date

  2013-09-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/jem.20130103PMID 24043761PMCID 3782045
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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