Daily omega-3 fatty acid intake and depression in Japanese patients with newly diagnosed lung cancer

The aim of the present study was to examine the association between daily omega-3 fatty acid intake and depression in Japanese cancer patients. Omega-3 fatty acid intake in 771 patients with newly diagnosed primary lung cancer was evaluated using a food-frequency questionnaire, and the prevalence of depression was examined using the cutoff values for the depression subscale included in the Hospital Anxiety and Depression Scale. After adjustment for potential confounding factors, the odds ratio (OR) for depression among patients in the highest quartile of the total eicosapentaenoic acid- (C20:5n-3) and docosapentaenoic acid (C22:6n-3)-intake group compared with patients in the lowest quartile was not significantly different. On the other hand, the OR among the highest quartile of α-linolenic acid (C18:3n-3) intake (adjusted OR=0.50, 95% CI: 0.31–0.71, P for trend=0.004) and the highest quartile of total omega-3 fatty acid intake (adjusted OR=0.55, 95% CI: 0.35–0.88, P for trend=0.022) were significantly different. These results suggest that total eicosapentaenoic acid and docosapentaenoic acid intake might not be associated with depression in Japanese patients with newly diagnosed lung cancer, but that α-linolenic acid intake and total omega-3 fatty acid intake might be.

• Publication year

  2004

• Venue

  British Journal of Cancer

• Publication date

  2004-02-17

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/sj.bjc.6601621PMID 14970854PMCID 2410186
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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