Effects of sleep on memory for conditioned fear and fear extinction.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Psychological bulletin

• Publication date

  2015-04-20

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1037/bul0000014PMID 25894546PMCID PMC4486610
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In Psychiatric Clinics of North America.

  2020cited by this paper
• The role of rapid eye movement sleep for amygdala-related memory processing.

  2015influential reference
• Effect of conditioned stimulus exposure during slow wave sleep on fear memory extinction in humans.

  2015influential reference
• Stress, arousal, and sleep.

  2015cited by this paper
• Sleep deprivation and gene expression.

  2015cited by this paper
• From circuits to behaviour in the amygdala

  2015cited by this paper
• Fear Conditioning, Safety Learning, and Sleep in Humans

  2014influential reference
• One night of partial sleep deprivation affects habituation of hypothalamus and skin conductance responses.

  2014cited by this paper
• Sleepiness induced by sleep-debt enhanced amygdala activity for subliminal signals of fear

  2014cited by this paper
• Ventromedial prefrontal cortex activity and rapid eye movement sleep are associated with subsequent fear expression in human subjects

  2014cited by this paper
• Differential Effects of Non-REM and REM Sleep on Memory Consolidation?

  2014cited by this paper
• The link between social anxiety disorder, treatment outcome, and sleep difficulties among patients receiving cognitive behavioral group therapy.

  2014cited by this paper
• Sleep and the processing of emotions

  2014cited by this paper
• One night of sleep is insufficient to achieve sleep-to-forget emotional decontextualisation processes

  2014cited by this paper
• Selective REM-Sleep Deprivation Does Not Diminish Emotional Memory Consolidation in Young Healthy Subjects

  2014cited by this paper
• The basolateral amygdala determines the effects of fear memory on sleep in an animal model of PTSD

  2014cited by this paper
• Opposing effects of D-cycloserine on fear despite a common extinction duration: interactions between brain regions and behavior.

  2014cited by this paper
• Interactions of time of day and sleep with between-session habituation and extinction memory in young adult males

  2014influential reference
• Slow-Wave Sleep-Imposed Replay Modulates Both Strength and Precision of Memory

  2014cited by this paper
• Yohimbine enhancement of exposure therapy for social anxiety disorder: a randomized controlled trial.

  2014cited by this paper
• The role of sleep in emotional brain function.

  2014cited by this paper
• The reorganisation of memory during sleep.

  2014cited by this paper
• The role of sleep and sleep deprivation in consolidating fear memories

  2013influential reference
• The role of REM sleep in the processing of emotional memories: evidence from behavior and event-related potentials.

  2013cited by this paper
• Blockade of estrogen by hormonal contraceptives impairs fear extinction in female rats and women.

  2013influential reference
• Sleep, plasticity and memory from molecules to whole-brain networks.

  2013influential reference
• Does Recall after Sleep-Dependent Memory Consolidation Reinstate Sensitivity to Retroactive Interference?

  2013cited by this paper
• A Systematic Review Assessing Bidirectionality between Sleep Disturbances, Anxiety, and Depression.

  2013cited by this paper
• The contextual brain: implications for fear conditioning, extinction and psychopathology

  2013cited by this paper
• SLEEP QUALITY PREDICTS TREATMENT OUTCOME IN CBT FOR SOCIAL ANXIETY DISORDER

  2013cited by this paper
• Deficient safety learning characterizes high trait anxious individuals.

  2013cited by this paper
• Sex differences in objective measures of sleep in post‐traumatic stress disorder and healthy control subjects

  2013cited by this paper
• Basolateral amygdala and the regulation of fear-conditioned changes in sleep: role of corticotropin-releasing factor.

  2013cited by this paper
• Sleep disturbances as the hallmark of PTSD: where are we now?

  2013cited by this paper
• Extinction of conditioned fear is better learned and recalled in the morning than in the evening.

  2013influential reference
• Sleep unbinds memories from their emotional context.

  2013cited by this paper
• Fear extinction and relapse: state of the art.

  2013cited by this paper
• Sleep to forget: interference of fear memories during sleep

  2013cited by this paper
• Effects of unconditioned stimulus intensity and fear extinction on subsequent sleep architecture in an afternoon nap

  2013influential reference
• Sleep enhances exposure therapy

  2013influential reference
• Memory suppression trades prolonged fear and sleep-dependent fear plasticity for the avoidance of current fear

  2013cited by this paper
• Rapid eye movement sleep does not seem to unbind memories from their emotional context

  2013cited by this paper
• Sleep and obsessive-compulsive disorder (OCD).

  2013cited by this paper
• Sleep-dependent memory triage: evolving generalization through selective processing

  2013influential reference
• Extinction, generalization, and return of fear: a critical review of renewal research in humans.

  2013cited by this paper
• Sleep Debt Elicits Negative Emotional Reaction through Diminished Amygdala-Anterior Cingulate Functional Connectivity

  2013cited by this paper
• The expected value of control: an integrative theory of anterior cingulate cortex function.

  2013cited by this paper
• Deficits in conditioned fear extinction in obsessive-compulsive disorder and neurobiological changes in the fear circuit.

  2013cited by this paper
• Diagnostic and Statistical Manual of Mental Disorders

  2013cited by this paper
• Hippocampus and striatum: Dynamics and interaction during acquisition and sleep‐related motor sequence memory consolidation

  2013cited by this paper
• Rapid remission of conditioned fear expression with extinction training paired with vagus nerve stimulation.

  2013cited by this paper
• About sleep's role in memory.

  2013influential reference
• Memory as a new therapeutic target

  2013cited by this paper
• Stimulus-specific enhancement of fear extinction during slow-wave sleep

  2013cited by this paper
• Fear Extinction Memory Consolidation Requires Potentiation of Pontine-Wave Activity during REM Sleep

  2013cited by this paper
• Auditory closed-loop stimulation of the sleep slow oscillation enhances memory.

  2013cited by this paper
• Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders

  2012cited by this paper
• Circadian Typology: A Comprehensive Review

  2012cited by this paper
• Effects of rapid eye movement sleep deprivation on fear extinction recall and prediction error signaling

  2012influential reference
• Sleep promotes consolidation and generalization of extinction learning in simulated exposure therapy for spider fear.

  2012cited by this paper
• Gender Differences in Sleep During the Aftermath of Trauma and the Development of Posttraumatic Stress Disorder

  2012cited by this paper
• Fear extinction as a model for translational neuroscience: ten years of progress.

  2012influential reference
• Sleep Deprivation Impairs Consolidation of Cued Fear Memory in Rats

  2012cited by this paper
• One's sex, sleep, and posttraumatic stress disorder

  2012cited by this paper
• Sleep promotes lasting changes in selective memory for emotional scenes

  2012cited by this paper
• Processing of Emotional Reactivity and Emotional Memory over Sleep

  2012cited by this paper
• Low estradiol levels: a vulnerability factor for the development of posttraumatic stress disorder.

  2012cited by this paper
• Generalization of contextual fear depends on associative rather than non-associative memory components.

  2012cited by this paper
• Resting cerebral metabolism correlates with skin conductance and functional brain activation during fear conditioning.

  2012cited by this paper
• The relationship of sleep quality and PTSD to anxious reactivity from idiographic traumatic event script-driven imagery.

  2012cited by this paper
• Sleep‐dependent modulation of affectively guided decision‐making

  2012cited by this paper
• Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways

  2012cited by this paper
• Sex differences, gonadal hormones and the fear extinction network: implications for anxiety disorders

  2012cited by this paper
• Stress-induced enhancement of fear conditioning and sensitization facilitates extinction-resistant and habituation-resistant fear behaviors in a novel animal model of posttraumatic stress disorder.

  2012cited by this paper
• Post-Exposure Sleep Deprivation Facilitates Correctly Timed Interactions Between Glucocorticoid and Adrenergic Systems, which Attenuate Traumatic Stress Responses

  2012cited by this paper
• Sex differences in the neurobiology of fear conditioning and extinction: a preliminary fMRI study of shared sex differences with stress-arousal circuitry

  2012cited by this paper
• Sleep quality among U.S. military veterans with PTSD: a factor analysis and structural model of symptoms.

  2012cited by this paper
• Enhanced emotional reactivity after selective REM sleep deprivation in humans: an fMRI study

  2012cited by this paper
• The function of the sleep spindle: a physiological index of intelligence and a mechanism for sleep-dependent memory consolidation.

  2011influential reference
• Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory.

  2011influential reference
• Effects of sex differences and regulation of the sleep-wake cycle on aversive memory encoding.

  2011cited by this paper
• The study of fear extinction: implications for anxiety disorders.

  2011influential reference
• The Neurocircuitry of Fear, Stress, and Anxiety Disorders

  2011cited by this paper
• Stress sensitization following a disaster: a prospective study

  2011cited by this paper
• Glucocorticoids enhance extinction-based psychotherapy

  2011cited by this paper
• REM Sleep Rebound as an Adaptive Response to Stressful Situations

  2011cited by this paper
• Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies.

  2011cited by this paper
• Sleep Deprivation Amplifies Reactivity of Brain Reward Networks, Biasing the Appraisal of Positive Emotional Experiences

  2011cited by this paper
• Insomnia as predictor versus outcome of PTSD and depression among Iraq combat veterans.

  2011influential reference
• Sleep Leads to Changes in the Emotional Memory Trace: Evidence from fMRI

  2011cited by this paper
• Unconditioned responses and functional fear networks in human classical conditioning.

  2011cited by this paper
• Estradiol modulates medial prefrontal cortex and amygdala activity during fear extinction in women and female rats.

  2011influential reference
• REM sleep depotentiates amygdala activity to previous emotional experiences.

  2011cited by this paper
• Adenosine, energy metabolism and sleep homeostasis.

  2011cited by this paper
• Emotional processing in anterior cingulate and medial prefrontal cortex.

  2011cited by this paper
• Fear is only as deep as the mind allows: A coordinate-based meta-analysis of neuroimaging studies on the regulation of negative affect

  2011cited by this paper
• The role of the ventromedial prefrontal cortex in memory consolidation.

  2011cited by this paper
• The role of norepinephrine in differential response to stress in an animal model of posttraumatic stress disorder.

  2011cited by this paper
• Antagonizing corticotropin-releasing factor in the central nucleus of the amygdala attenuates fear-induced reductions in sleep but not freezing.

  2011cited by this paper
• Napping promotes inter-session habituation to emotional stimuli.

  2011influential reference

• Prefrontal activation and inhibitory performance in the association between anxiety and sleep quality: An fNIRS investigation.

  2026cites this paper
• The impact of temporal distribution on fear extinction learning

  2025cites this paper
• Objective prenatal sleep and adverse childhood experiences in a proof-of-concept observational mixed methods study

  2025cites this paper
• Neural circuits and emotional processing in rapid eye movement sleep

  2025cites this paper
• Differential Associations Between Sleep Domains and Response to Prolonged Exposure Therapy

  2025cites this paper
• Restricted retrieval enhances extinction memory generalization across time and context

  2025cites this paper
• The Bidirectional Relationship between Sleep Disturbance and Exposure-Based Treatment for Social Anxiety Disorder: A Multi-Method Examination

  2025cites this paper
• Sleep deprivation affects memory function, depression and anxiety-like behaviours in rats and mice: a systematic review and meta-analysis

  2025cites this paper
• Sleep's contribution to memory formation.

  2025cites this paper
• Does sleep change the emotional bias in memory in older adults?

  2025cites this paper
• Anxiolytic effects of corilagin by targeting Htr2c through activation of the TrkB/CREB/BDNF pathway.

  2025cites this paper
• Sleep and the recovery from stress.

  2025cites this paper
• Sleep’s Role for Enhancing Extinction Memory in Anxiety Disorders: Implications for Exposure Therapy

  2025cites this paper
• Using sleep to enhance exposure treatment for anxious children: A pilot study.

  2025cites this paper
• Effects of anxiety induced by conditioned fear on the expression of NMDA receptors and synaptic plasticity in the rat BLA.

  2025cites this paper
• Trauma Under Psychedelics: How Psychoactive Substances Impact Trauma Processing

  2025cites this paper
• Sleep to remember, sleep to protect: increased sleep spindle and theta activity predict fewer intrusive memories after analogue trauma

  2025cites this paper
• NREM Sleep EEG Characteristics Following Written Trauma Memory Exposure: An Exploratory Study of Power and Spindle‐Phase Dynamics

  2025cites this paper
• Acute sleep deprivation reduces fear memories in male and female mice

  2024cites this paper
• REM disruption and REM vagal activity predict extinction recall in trauma-exposed individuals

  2024cites this paper
• The Improvement in Sleep Quality by Zizyphi Semen in Rodent Models Through GABAergic Transmission Regulation

  2024cites this paper
• The impact of exercise interventions on sleep in adult populations with depression, anxiety, or posttraumatic stress: review of the current evidence and future directions

  2024cites this paper
• Effects of Sleep Deficiency on Risk, Course, and Treatment of Psychopathology.

  2024cites this paper
• Sleep and adjustment in foster environments for toddlers and preschoolers (SAFE-T): Initial efficacy of a trauma-informed sleep intervention for young children in foster care.

  2024cites this paper
• Effects of intranasal oxytocin on fear extinction learning

  2024cites this paper
• Acute sleep disruption reduces fear memories in male and female mice

  2024cites this paper
• The moderating effect of resilience in the association between insomnia severity and PTSD symptoms in Lebanese adolescents in the aftermath of the 2023 earthquake

  2024cites this paper
• Sleep deprivation increases the generalization of perceptual and concept-based fear: An fNIRS study.

  2024cites this paper
• REM Sleep Preserves Affective Response to Social Stress—Experimental Study

  2024cites this paper
• The effect of REM-sleep disruption on affective processing: A systematic review of human and animal experimental studies.

  2024cites this paper
• Chronic pain as an emergent property of a complex system and the potential roles of psychedelic therapies

  2024cites this paper
• A scalable spiking amygdala model that explains fear conditioning, extinction, renewal and generalization

  2024cites this paper
• Independent and Joint Associations of Physical Activity and Sleep on Mental Health Among a Global Sample of 200,743 Adults

  2024cites this paper
• The effect of anxiety on sleep disorders in medical students: a moderated mediation model

  2024cites this paper
• Sleep-wake dependent hippocampal regulation of fear memory.

  2024cites this paper
• Infralimbic activity during REM sleep facilitates fear extinction memory

  2024cites this paper
• Gender congruence and emotion effects in cross-modal associative learning: Insights from ERPs and pupillary responses.

  2023cites this paper
• Association of obstructive sleep apnea and sleep quality with cognitive function: a study of middle-aged and elderly persons in India

  2023cites this paper
• The importance of REM sleep fragmentation in the effects of stress on sleep: Perspectives from preclinical studies

  2023cites this paper
• REM disruption and REM Vagal Activity Predict Extinction Recall in Trauma-Exposed Individuals

  2023cites this paper
• Blunted glucocorticoid responsiveness to stress causes behavioral and biological alterations that lead to posttraumatic stress disorder vulnerability

  2023cites this paper
• The relationship between sleep and appetitive conditioning: A systematic review and meta-analysis.

  2023cites this paper
• A REM-active basal ganglia circuit that regulates anxiety

  2023cites this paper
• Predicting Fear Extinction in Posttraumatic Stress Disorder

  2023cites this paper
• Phytotherapy of abnormality of fear memory: A narrative review of mechanisms.

  2023cites this paper
• A prolonged stress rat model recapitulates some PTSD-like changes in sleep and neuronal connectivity

  2023cites this paper
• Effects of sleep disturbance on trauma‐focused psychotherapy outcomes in posttraumatic stress disorder: A systematic review

  2023cites this paper
• From childhood adversity to latent stress vulnerability in adulthood: the mediating roles of sleep disturbances and HPA axis dysfunction

  2023cites this paper
• Neural correlates of immediate versus delayed extinction when simultaneously varying the time of the test in humans.

  2023cites this paper
• Antisense oligonucleotides targeting basal forebrain ATXN2 enhances spatial memory and ameliorates sleep deprivation‐induced fear memory impairment in mice

  2023cites this paper
• CaMKIIa Neurons of the Ventromedial Hypothalamus Mediate Wakefulness and Anxiety-like Behavior

  2023cites this paper
• Subjective Sleep Disturbances in Sexual Assault Survivors: Associations With Trauma and Posttraumatic Stress Disorder Symptom Severity.

  2023cites this paper
• Beta spectral power during sleep is associated with impaired recall of extinguished fear

  2023cites this paper
• Pontine control of rapid eye movement sleep and fear memory

  2023cites this paper
• Role of pontine sub‐laterodorsal tegmental nucleus (SLD) in rapid eye movement (REM) sleep, cataplexy, and emotion

  2022cites this paper
• Nightmares and psychiatric symptoms: A systematic review of longitudinal, experimental, and clinical trial studies

  2022cites this paper
• Atypical hypnotic compound ML297 restores sleep architecture immediately following emotionally valenced learning, to promote memory consolidation and hippocampal network activation during recall

  2022cites this paper
• The effects of the recurrent social isolation stress on fear extinction and dopamine D2 receptors in the amygdala and the hippocampus

  2022cites this paper
• The influence of sleep on fear extinction in trauma-related disorders

  2022influential citation
• The influence of being left behind on fear acquisition and academic performance—a study of left-behind children

  2022cites this paper
• Sex differences in the effect of subjective sleep on fear conditioning, extinction learning, and extinction recall in individuals with a range of PTSD symptom severity.

  2022cites this paper
• Enhancing imagery rehearsal therapy for nightmares with targeted memory reactivation.

  2022cites this paper
• Effect of evaluation timing and duration of anxiety-like behaviors induced by conditioned fear in rats: Assessment using the triple test.

  2022cites this paper
• Psychoneurological Symptoms and Biomarkers of Stress and Inflammation in Newly Diagnosed Head and Neck Cancer Patients: A Network Analysis

  2022cites this paper
• Boosting psychological change: combining non-invasive brain stimulation with psychotherapy.

  2022cites this paper
• Sleep disturbance and suicide risk among sexual and gender minority people

  2022cites this paper
• Roles for Sleep in Neural and Behavioral Plasticity: Reviewing Variation in the Consequences of Sleep Loss

  2022cites this paper
• Morning blue light treatment improves sleep complaints, symptom severity, and retention of fear extinction memory in post-traumatic stress disorder

  2022cites this paper
• Atypical hypnotic compound ML297 restores sleep architecture following emotionally-valenced learning, to promote memory consolidation and hippocampal network activation during recall

  2022cites this paper
• Alpha-2 Adrenoreceptor Antagonist Yohimbine Potentiates Consolidation of Conditioned Fear

  2022cites this paper
• Effects of Sleep Deficiency on Risk, Course, and Treatment of Psychopathology.

  2022cites this paper
• Sleep Deprivation During Memory Consolidation, but Not Before Memory Retrieval, Widens Threat Generalization to New Stimuli

  2022cites this paper
• Is PTSD an Evolutionary Survival Adaptation Initiated by Unrestrained Cytokine Signaling and Maintained by Epigenetic Change?

  2022cites this paper
• Sleep disorders and non-sleep circadian disorders predict depression: a systematic review and meta-analysis of longitudinal studies.

  2022cites this paper
• Sleep spindles favor emotion regulation over memory consolidation of stressors in PTSD

  2022cites this paper
• Combined treatment of nightmares with targeted memory reactivation and imagery rehearsal therapy: a randomized controlled trial

  2022cites this paper
• A Narrative Review of the Association between Post-Traumatic Stress Disorder and Obstructive Sleep Apnea

  2022cites this paper
• Neural Circuits Underlying Behavioral Flexibility: Insights From Drosophila

  2022cites this paper
• Cannabidiol in the context of sleeping disorders-induced oxidative stress

  2022cites this paper
• An Analysis of Fear Inhibition and Fear Extinction in a Sample of Veterans with Obstructive Sleep Apnea (OSA): Implications for Co-morbidity with Post-Traumatic Stress Disorder (PTSD).

  2021cites this paper
• Intimate Partner Violence and Sleep: An Overview of Sleep Disturbances and Interventions

  2021cites this paper
• Characterizing human safety learning via Pavlovian conditioned inhibition.

  2021cites this paper
• Sleep to Remember, Sleep to Forget: Rapid Eye Movement Sleep Can Have Inverse Effects on Recall and Generalization of Fear Memories.

  2021cites this paper
• Tracking Eye Movements During Sleep in Mice

  2021cites this paper
• The why and how of sleep-dependent synaptic down-selection.

  2021cites this paper
• Manipulation of REM sleep via orexin and GABAA receptor modulators differentially affects fear extinction in mice: effect of stable versus disrupted circadian rhythm.

  2021cites this paper
• Altered sleep behavior in a genetic mouse model of impaired fear extinction

  2021cites this paper
• Basolateral amygdala regulates EEG theta-activity during rapid eye movement sleep.

  2021cites this paper
• REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse

  2021cites this paper
• Examining the effects of time of day and sleep on generalization

  2021cites this paper
• Neural signature of delayed fear generalization under stress.

  2021cites this paper
• Prefrontal cortex, amygdala, and threat processing: implications for PTSD

  2021cites this paper
• A neurocomputational theory of nightmares: the role of formal properties of nightmare images

  2021cites this paper
• Sleeping over moral dilemmas modulates utilitarian decision-making

  2021cites this paper
• The prevalence and severity of insomnia in university students and their associations with migraine, tension-type headache, anxiety and depression disorders: a cross-sectional study.

  2021cites this paper
• Associations of sleep measures with neural activations accompanying fear conditioning and extinction learning and memory in trauma-exposed individuals.

  2021cites this paper
• The Basolateral Amygdala Mediates the Role of Rapid Eye Movement Sleep in Integrating Fear Memory Responses

  2021cites this paper
• Blocking the orexin system following therapeutic exposure promoted between session habituation, but not PTSD symptom reduction.

  2021cites this paper
• A dynamic causal model on self-regulation of aversive emotion

  2020cites this paper
• Learning dynamics of electrophysiological brain signals during human fear conditioning

  2020cites this paper