Stable therapeutic effects of mesenchymal stem cell-based multiple gene delivery for cardiac repair.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Cardiovascular Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/CVR/CVM077PMID 18032392
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Maximizing Ventricular Function With Multimodal Cell-Based Gene Therapy

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• Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction.

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