Excessive Sympathetic Activation in Heart Failure With Obesity and Metabolic Syndrome: Characteristics and Mechanisms

No abstract is available for this paper.

• Publication year

  2007

• Venue

  HYPERTENSION

• Publication date

  2007-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.HYP.0000255983.32896.b9PMID 17210829
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Metabolic syndrome and risk for heart failure in middle-aged men

  2006cited by this paper
• Mechanisms of sympathetic activation in obesity-related hypertension.

  2006cited by this paper
• Short Sleep Duration as a Risk Factor for Hypertension: Analyses of the First National Health and Nutrition Examination Survey

  2006cited by this paper
• Diagnosis and management of the metabolic syndrome

  2005cited by this paper
• Effects of dietary weight loss on sympathetic activity and cardiac risk factors associated with the metabolic syndrome.

  2005cited by this paper
• Insulin resistance and risk of congestive heart failure.

  2005cited by this paper
• Neuroadrenergic and reflex abnormalities in patients with metabolic syndrome

  2005cited by this paper
• Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement.

  2005cited by this paper
• Prevalence and impact of metabolic syndrome on hospital outcomes in acute myocardial infarction.

  2005cited by this paper
• Effects of candesartan on cardiac sympathetic nerve activity in patients with congestive heart failure and preserved left ventricular ejection fraction.

  2005cited by this paper
• Sympathetic Neural Activation in Nondiabetic Metabolic Syndrome and Its Further Augmentation by Hypertension

  2004cited by this paper
• Leptin, sympathetic nervous system, and baroreflex function

  2004cited by this paper
• Clinical Importance of Obesity Versus the Metabolic Syndrome in Cardiovascular Risk in Women: A Report From the Women’s Ischemia Syndrome Evaluation (WISE) Study

  2004cited by this paper
• Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives

  2004cited by this paper
• Effects of Hypertension and Obesity on the Sympathetic Activation of Heart Failure Patients

  2003cited by this paper
• Nonselective Versus Selective &bgr;-Adrenergic Receptor Blockade in Congestive Heart Failure: Differential Effects on Sympathetic Activity

  2001cited by this paper
• Sympathetic and reflex abnormalities in heart failure secondary to ischaemic or idiopathic dilated cardiomyopathy.

  2001cited by this paper
• Effects of amlodipine on sympathetic nerve traffic and baroreflex control of circulation in heart failure.

  1999cited by this paper
• How to assess sympathetic activity in humans.

  1999cited by this paper
• Sympathetic activity in obese subjects with and without obstructive sleep apnea.

  1998cited by this paper
• Baroreflex control of sympathetic nerve activity in essential and secondary hypertension.

  1998cited by this paper
• Comparison between reproducibility and sensitivity of muscle sympathetic nerve traffic and plasma noradrenaline in man.

  1997cited by this paper
• Effects of chronic ACE inhibition on sympathetic nerve traffic and baroreflex control of circulation in heart failure.

  1997cited by this paper
• Sympathetic activation in obese normotensive subjects.

  1995cited by this paper
• Sympathetic activation and loss of reflex sympathetic control in mild congestive heart failure.

  1995cited by this paper
• Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality

  1991cited by this paper
• Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD).

  1990cited by this paper
• Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group.

  1990cited by this paper
• Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms.

  1989cited by this paper
• Elevated Sympathetic Nerve Activity in Borderline Hypertensive Humans Evidence From Direct Intraneural Recordings

  1989cited by this paper
• Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity.

  1986cited by this paper
• Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure.

  1986cited by this paper
• Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure.

  1984cited by this paper
• Measurements of plasma norepinephrine concentrations in human primary hypertension. A word of caution on their applicability for assessing neurogenic contributions.

  1983cited by this paper
• Determination of plasma catecholamines by high performance liquid chromatography with electrochemical detection: comparison with a radioenzymatic method.

  1979cited by this paper

• The impact of physical activity levels and cardiorespiratory fitness on heart rate variability in overweight and obese college students: a cross-sectional study

  2026cites this paper
• Coronary microvascular dysfunction: pathophysiology, diagnosis, and therapeutic strategies across cardiovascular diseases

  2025cites this paper
• Do obesity and visceral adiposity promote heart failure with reduced ejection fraction?

  2025cites this paper
• Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives

  2025cites this paper
• The Impact of Obesity on Cardiovascular Diseases: Heart Failure

  2025cites this paper
• Coronary Microvascular Dysfunction in Ischaemic Heart Disease: Lessons From Large Animal Models

  2025cites this paper
• Harmony in Chaos: Deciphering the Influence of Ischemic Cardiomyopathy and Non-Cardiac Comorbidities on Holter ECG Parameters in Chronic Heart Failure Patients: A Pilot Study

  2024cites this paper
• The cAMP/PKA signaling pathway conditions cardiac performance in experimental animals with metabolic syndrome.

  2024cites this paper
• Arterial Hypertension in Patients with Takotsubo Syndrome: Prevalence, Long-Term Outcome, and Secondary Preventive Strategies. A Report from the Takotsubo Italian Network Register.

  2023cites this paper
• Coronary Microvascular Dysfunction in Diabetes Mellitus: Pathogenetic Mechanisms and Potential Therapeutic Options

  2022cites this paper
• Influence of sex and age on the relationship between aerobic fitness and muscle sympathetic nerve activity in healthy adults.

  2022cites this paper
• Neuroadrenergic activation in obstructive sleep apnoea syndrome: a new selected meta-analysis - revisited

  2022cites this paper
• Neuroadrenergic activation in obstructive sleep apnea syndrome: a systematic review and meta-analysis

  2021cites this paper
• Autonomic nervous system function in women with anorexia nervosa

  2021cites this paper
• Vascular Failure

  2021cites this paper
• CENTRAL AND PERIPHERAL SYMPATHETIC ACTIVATION IN HEART FAILURE.

  2021cites this paper
• The Role of Biosemiosis and Dysfunctional Signaling Processes in Human Pathology

  2021cites this paper
• In silico trial of baroreflex activation therapy for the treatment of obesity-induced hypertension

  2021cites this paper
• ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on 'coronary microvascular dysfunction in cardiovascular disease'.

  2020cites this paper
• High Fructose Corn Syrup Sweetened Soft Drink Consumption Increases Vascular Resistance in the Kidneys at Rest and during Sympathetic Activation.

  2020cites this paper
• Serum adiponectin is a potential biomarker for metabolic syndrome in peri-and postmenopausal women

  2020cites this paper
• Supplementation with a Carob (Ceratonia siliqua L.) Fruit Extract Attenuates the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice

  2020cites this paper
• Sympathetic nervous system activity and reactivity in women with gestational diabetes mellitus

  2020cites this paper
• Sympathomodulation in congestive heart failure: From drugs to devices.

  2020cites this paper
• Impact of sex and age on metabolism, sympathetic activity, and hypertension

  2020cites this paper
• Sympathetic Overactivation in Patients With Essential Hypertension and Hepatic Iron Overload

  2020cites this paper
• A Cognitive and Emotional Self: A Dynamic Relationship between a Dual Self Embedded in the Autonomic Nervous System

  2020cites this paper
• Oxidative Stress in Ischemic Heart Disease

  2020cites this paper
• Neurohormonal and metabolic profile of heart failure in obese versus non-obese patients

  2020cites this paper
• Sympathetic Nerve Traffic and Arterial Baroreflex Function in Apparent Drug-Resistant Hypertension.

  2019cites this paper
• Sympathetic neural overdrive in congestive heart failure and its correlates: systematic reviews and meta-analysis.

  2019cites this paper
• Sex differences in sympathetic activity in obesity and its related hypertension

  2019cites this paper
• Sympathetic Neural Overdrive in the Obese and Overweight State.

  2019cites this paper
• Sympathetic activity in obesity: a brief review of methods and supportive data

  2019cites this paper
• Risk of heart failure progression in patients with reduced ejection fraction: mechanisms and therapeutic options

  2019cites this paper
• Sympathetic renal denervation for resistant hypertension : impact on blood pressure and on surrogate markers of target organ damage

  2019cites this paper
• Overview of the Comorbidity Between Medical Illnesses and Overweight/Obesity

  2019cites this paper
• Coronary Microvascular Dysfunction in Cardiovascular Disease: Lessons from Large Animal Models

  2019cites this paper
• Molecular Regulatory Pathways Link Sepsis With Metabolic Syndrome: Non-coding RNA Elements Underlying the Sepsis/Metabolic Cross-Talk

  2018cites this paper
• Diagnostic imaging in the management of patients with metabolic syndrome

  2018cites this paper
• Intracranial Pressure Is a Determinant of Sympathetic Activity

  2018cites this paper
• Sympathetic Nervous System Regulation in Human Normotensive and Hypertensive Pregnancies

  2018cites this paper
• Residual vascular dysfunction in women with a history of preeclampsia.

  2018cites this paper
• The role of increased glucose on neurovascular dysfunction in patients with the metabolic syndrome

  2017cites this paper
• Effect of bariatric surgery on heart failure

  2017cites this paper
• Cardiovascular consequences of metabolic syndrome.

  2017cites this paper
• Cardiac and peripheral autonomic control in restrictive cardiomyopathy

  2017cites this paper
• 11β-Hydroxysteroid Dehydrogenases and Hypertension in the Metabolic Syndrome

  2017cites this paper
• Muscle Sympathetic Nerve Activity Is Associated With Elements of the Plasma Lipidomic Profile in Young Asian Adults

  2017cites this paper
• HEMODYNAMIC AND CARDIAC EFFECTS OF OBESITY AND THE METABOLIC SYNDROME

  2017cites this paper
• Study on autonomic dysfunction and metabolic syndrome in Chinese patients

  2016cites this paper
• Sympathetic Nervous System, Hypertension, Obesity and Metabolic Syndrome

  2016cites this paper
• Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension: obesity and heart failure.

  2016cites this paper
• Prevalence and Prognostic Impact of Metabolic Syndrome in Asymptomatic (Stage A and B Heart Failure) Patients

  2016influential citation
• Target organ complications and prognostic significance of alerting reaction: analysis from the Dallas Heart Study

  2016cites this paper
• Autonomic function in rheumatoid arthritis

  2016cites this paper
• Role of the carotid body in metabolic disturbances

  2016cites this paper
• Cardiometabolic crosstalk in obesity-associated arterial hypertension

  2016cites this paper
• Carotid Baroreceptor Stimulation

  2016cites this paper
• Baroreflex Activation Therapy in Congestive Heart Failure: Novel Findings and Future Insights

  2016cites this paper
• Renal denervation for resistant hypertension.

  2015cites this paper
• Selective Heart Rate Reduction Improves Metabolic Syndrome–related Left Ventricular Diastolic Dysfunction

  2015cites this paper
• Diabetes and Metabolic Syndrome

  2015cites this paper
• Alpha-linolenic acid protects against cardiac injury and remodelling induced by beta-adrenergic overstimulation.

  2015cites this paper
• Carotid body, insulin, and metabolic diseases: unraveling the links

  2014cites this paper
• The future of interventional management of hypertension: threats and opportunities.

  2014cites this paper
• Chronic baroreflex activation effects on sympathetic nerve traffic, baroreflex function, and cardiac haemodynamics in heart failure: a proof-of-concept study

  2014cites this paper
• Marked sympathetic activation and baroreflex dysfunction in true resistant hypertension.

  2014cites this paper
• Catheter-based Renal Sympathetic Denervation - Long-term Symplicity™ Renal Denervation Clinical Evidence, New Data and Future Perspectives.

  2013cites this paper
• How to assess sympathetic nervous system activity in clinical practice.

  2013cites this paper
• Pulse pressure and heart rate in patients with metabolic syndrome across Europe: insights from the GOOD survey

  2013cites this paper
• Efficacy of regional renal nerve blockade in patients with chronic refractory heart failure.

  2013cites this paper
• Obesity and its association to phenotype and clinical course in hypertrophic cardiomyopathy.

  2013cites this paper
• Expanding the indication spectrum: renal denervation in diabetes.

  2013cites this paper
• compound selective for I 1-imidazoline receptors improves metabolic syndrome in rats

  2013influential citation
• Asymptomatic Left Ventricular Dysfunction and Metabolic Syndrome: Results from an Italian Multicenter Study

  2013cites this paper
• A New Pyrroline Compound Selective for I1-Imidazoline Receptors Improves Metabolic Syndrome in Rats

  2013influential citation
• Obesity and heart failure.

  2013cites this paper
• The human sympathetic nervous system: its relevance in hypertension and heart failure.

  2012cites this paper
• Abnormal sympathetic reactivity to the cold pressor test in overweight humans.

  2012cites this paper
• Left Ventricular Mass and Function With Reduced-Fat or Reduced-Carbohydrate Hypocaloric Diets in Overweight and Obese Subjects

  2012cites this paper
• Accessing Autonomic Function Can Early Screen Metabolic Syndrome

  2012cites this paper
• Upregulation of the Renin-Angiotensin-Aldosterone-Ouabain System in the Brain Is the Core Mechanism in the Genesis of All Types of Hypertension

  2012cites this paper
• Effects of acupuncture and exercise on insulin sensitivity, adipose tissue characteristics, and markers of coagulation and fibrinolysis in women with polycystic ovary syndrome: secondary analyses of a randomized controlled trial.

  2012cites this paper
• Treatment with low-dose resveratrol reverses cardiac impairment in obese prone but not in obese resistant rats.

  2012cites this paper
• Central Resistin Enhances Renal Sympathetic Nerve Activity via Phosphatidylinositol 3‐Kinase but Reduces the Activity to Brown Adipose Tissue via Extracellular Signal‐Regulated Kinase 1/2

  2012cites this paper
• Increased daily sodium intake is an independent dietary indicator of the metabolic syndrome in middle-aged subjects

  2012cites this paper
• Potential Cardiometabolic Benefits of Renal Artery Denervation in Diabetics

  2012cites this paper
• Investigating the cardiovascular and metabolic effects of resistin

  2012influential citation
• Chapter 76 – Heart Failure

  2012cites this paper
• Intérêt de la variabilité du rythme cardiaque comme marqueur de risque

  2012cites this paper
• IMPACT OF OBESITY ON THE PHENOTYPE AND CLINICAL COURSE OF HYPERTROPHIC CARDIOMYOPATHY

  2012cites this paper
• Dietary fructose, salt absorption and hypertension in metabolic syndrome: towards a new paradigm

  2011cites this paper
• Improvement of left ventricular diastolic function induced by β-blockade: a comparison between nebivolol and metoprolol.

  2011cites this paper
• The Role of Salt in the Pathogenesis of Fructose-Induced Hypertension

  2011cites this paper
• The ‘neuroadrenergic hypothesis’ in hypertension: current evidence

  2010cites this paper
• Reinforcement of the adrenergic overdrive in the metabolic syndrome complicated by obstructive sleep apnea

  2010cites this paper
• Impact of sleep disordered breathing severity on hemodynamics, autonomic balance and cardiopulmonary functional status in chronic heart failure.

  2010cites this paper
• Efecto del ejercicio en la variabilidad de la frecuencia cardíaca

  2010cites this paper
• Obesity and daytime pulse pressure are predictors of left ventricular hypertrophy in true normotensive individuals

  2010cites this paper