Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice1

The regulation and function of IgE in healthy individuals and in antigen‐naïve animals is not well understood. IL‐33 administration increases serum IgE in mice with unknown mechanism. We tested the hypothesis that IL‐33 provides an antigen‐independent stimulus for IgE production and mast cell degranulation.

• Publication year

  2012

• Venue

  Allergy. European Journal of Allergy and Clinical Immunology

• Publication date

  2012-06-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1398-9995.2012.02859.xPMID 22702477PMCID 3660789
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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