Different respiratory-defective phenotypes of Neurospora crassa and Saccharomyces cerevisiae after inactivation of the gene encoding the mitochondrial acyl carrier protein

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Current Genetics

• Publication date

  1995-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF00313188PMID 8595652
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Quantitative analysis of phospholipids by thin-layer chromatography and phosphorus analysis of spots

  2007cited by this paper
• in Yeast Mitochondria

  2005cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Inactivation of genes encoding subunits of the peripheral and membrane arms of neurospora mitochondrial complex I and effects on enzyme assembly.

  1995cited by this paper
• [1] Generation and characterization of NADH: Ubiquinone oxidoreductase mutants in Neurospora crassa

  1995cited by this paper
• Generation and characterization of NADH: ubiquinone oxidoreductase mutants in Neurospora crassa.

  1995cited by this paper
• Isolation and characterization of the proton-translocating NADH: ubiquinone oxidoreductase from Escherichia coli.

  1995cited by this paper
• The Characterization of a Mitochondrial Acyl Carrier Protein Isoform Isolated from Arabidopsis thaliana

  1994cited by this paper
• Disruption of the gene encoding the NADH-binding subunit of NADH: ubiquinone oxidoreductase in Neurospora crassa. Formation of a partially assembled enzyme without FMN and the iron-sulphur cluster N-3.

  1994cited by this paper
• Lipid peroxidation-induced membrane structural alterations.

  1994cited by this paper
• Subcellular relocalization of a long‐chain fatty acid CoA ligase by a suppressor mutation alleviates a respiration deficiency in Saccharomyces cerevisiae.

  1994cited by this paper
• The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

  1994cited by this paper
• Attempts to define distinct parts of NADH: Ubiquinone oxidoreductase (complex I)

  1993cited by this paper
• DNA sequence analysis of the YCN2 region of chromosome XI in Saccharomyces cerevisiae

  1993cited by this paper
• A high copy number of yeast γ-glutamylcysteine synthetase suppresses a nuclear mutation affecting mitochondrial translation

  1993cited by this paper
• Identification of a new nuclear gene (CEM1) encoding a protein homologous to a β‐keto‐acyl synthase which is essential for mitochondrial respiration in Saccharomyces cerevisiae

  1993cited by this paper
• DNA sequencing of the seven remaining structural genes of the gene cluster encoding the energy-transducing NADH-quinone oxidoreductase of Paracoccus denitrificans.

  1993cited by this paper
• Parameters affecting lithium acetate-mediated transformation of Saccharomyces cerevisiae and development of a rapid and simplified procedure

  1993cited by this paper
• Regulation of fatty acid biosynthesis in Escherichia coli.

  1993cited by this paper
• The gene locus of the proton-translocating NADH: ubiquinone oxidoreductase in Escherichia coli. Organization of the 14 genes and relationship between the derived proteins and subunits of mitochondrial complex I.

  1993cited by this paper
• Regulation and function of rhizobial nodulation genes.

  1993cited by this paper
• Regulatory sequences in the transcription of Neurospora crassa genes: CAAT box, TATA box, Introns, Poly(A) tail formation sequences

  1993cited by this paper
• The biochemistry and molecular biology of plant lipid biosynthesis

  1992cited by this paper
• De novo synthesis and desaturation of fatty acids at the mitochondrial acyl‐carrier protein, a subunit of NADH:ubiquinone oxidoreductase in Neurospora crassa

  1992cited by this paper
• Characterization of assembly intermediates of NADH:ubiquinone oxidoreductase (complex I) accumulated in Neurospora mitochondria by gene disruption.

  1992cited by this paper
• The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains

  1992cited by this paper
• Presence of an acyl carrier protein in NADH:ubiquinone oxidoreductase from bovine heart mitochondria

  1991cited by this paper
• The pentafunctional FAS1 genes of Saccharomyces cerevisiae and Yarrowia lipolytica are co-linear and considerably longer than previously estimated

  1991cited by this paper
• Electron microscopic analysis of the peripheral and membrane parts of mitochondrial NADH dehydrogenase (complex I).

  1991cited by this paper
• The respiratory-chain NADH dehydrogenase (complex I) of mitochondria.

  1991cited by this paper
• Relationship between a subunit of NADH dehydrogenase (complex I) and a protein family including subunits of cytochrome reductase and processing protease of mitochondria

  1991cited by this paper
• The iron-sulfur clusters in the two related forms of mitochondrial NADH: ubiquinone oxidoreductase made by Neurospora crassa.

  1991cited by this paper
• Organelle biogenesis and intracellular lipid transport in eukaryotes.

  1991cited by this paper
• The acyl-carrier protein in Neurospora crassa mitochondria is a subunit of NADH:ubiquinone reductase (complex I).

  1991cited by this paper
• Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier protein-dependent fatty acylation

  1991cited by this paper
• De novo fatty acid synthesis mediated by acyl-carrier protein in Neurospora crassa mitochondria.

  1990cited by this paper
• PET genes of Saccharomyces cerevisiae.

  1990cited by this paper
• Lipid damage and repair

  1990cited by this paper
• Assembly of NADH: ubiquinone reductase (complex I) in Neurospora mitochondria. Independent pathways of nuclear-encoded and mitochondrially encoded subunits.

  1990cited by this paper
• Molecular genetics of polyketides and its comparison to fatty acid biosynthesis.

  1990cited by this paper
• The 49 K subunit of NADH: ubiquinone reductase (complex I) from Neurospora crassa mitochondria: primary structure of the gene and the protein

  1990cited by this paper
• A small isoform of NADH:ubiquinone oxidoreductase (complex I) without mitochondrially encoded subunits is made in chloramphenicol-treated Neurospora crassa.

  1989cited by this paper
• 18 – One-Step Gene Disruption in Yeast

  1989cited by this paper
• Purification and characterization of a rotenone-insensitive NADH:Q6 oxidoreductase from mitochondria of Saccharomyces cerevisiae.

  1988cited by this paper
• Neurospora mitochondria contain an acyl-carrier protein.

  1988cited by this paper
• A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector.

  1987cited by this paper
• A new role for phospholipase A2: protection of membranes from lipid peroxidation damage

  1987cited by this paper
• Yeast/E. coli shuttle vectors with multiple unique restriction sites

  1986cited by this paper
• Cloning and characterization of the gene for beta-tubulin from a benomyl-resistant mutant of Neurospora crassa and its use as a dominant selectable marker

  1986cited by this paper
• Lipids of mitochondria.

  1985cited by this paper
• Analysis of phospholipids in human semen by high-performance liquid chromatography.

  1983influential reference
• Studies on transformation of Escherichia coli with plasmids.

  1983cited by this paper
• One-step gene disruption in yeast.

  1983cited by this paper
• Bacterial production of antibiotic polypeptides by thiol-linked synthesis on protein templates.

  1980cited by this paper
• Methods in yeast genetics

  1979cited by this paper
• An accurate and convenient organic phosphorus assay.

  1971cited by this paper
• CARDIOLIPIN CONTENT OF WILD TYPE AND MUTANT YEASTS IN RELATION TO MITOCHONDRIAL FUNCTION AND DEVELOPMENT

  1971cited by this paper
• [4] Genetic and microbiological research techniques for Neurospora crassa

  1970cited by this paper
• Characterization of Neurospora crassa mitochondria prepared with a grind-mill.

  1970cited by this paper
• Laboratory contaminants in lipid chemistry: Detection by thin-layer chromatography and infrared spectrophotometry and some procedures minimizing their occurrence

  1966cited by this paper
• A simple method for the isolation and purification of total lipides from animal tissues.

  1957cited by this paper

• Mitochondrial fatty acid synthesis: The physiopathological role in cellular processes and human diseases

  2026cites this paper
• A mouse model of MEPAN demonstrates a role for mitochondrial fatty acid synthesis in iron–sulfur cluster and supercomplex formation

  2025cites this paper
• The complex I subunit B22 contains a LYR domain that is crucial for an interaction with the mitochondrial acyl carrier protein SDAP1

  2025cites this paper
• Sugar-Induced Cell Death in the Yeast S. cerevisiae Is Accompanied by the Release of Octanoic Acid, Which Does Not Originate from the Fatty Acid Synthesis Type II Mitochondrial System

  2023cites this paper
• Mitochondrial fatty acid synthesis is an emergent central regulator of mammalian oxidative metabolism.

  2023cites this paper
• A hub for regulation of mitochondrial metabolism: Fatty acid and lipoic acid biosynthesis

  2023cites this paper
• Mitochondrial Acyl Carrier Protein of Leishmania major Displays Features Distinct from the Canonical Type II ACP.

  2023cites this paper
• Patient-Derived Cellular Models for Polytarget Precision Medicine in Pantothenate Kinase-Associated Neurodegeneration

  2023cites this paper
• Loss of Mitochondrial Enoyl CoA Reductase causes elevated ceramide levels and impairs iron metabolism

  2023cites this paper
• A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide levels

  2023cites this paper
• Critical Roles of Mitochondrial Fatty Acid Synthesis in Tomato Development and Environmental Response.

  2022cites this paper
• Down regulation of the expression of mitochondrial phosphopantetheinyl-proteins in pantothenate kinase-associated neurodegeneration: pathophysiological consequences and therapeutic perspectives

  2021cites this paper
• Mitochondrial Fatty Acids and Neurodegenerative Disorders

  2020cites this paper
• Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria

  2020cites this paper
• Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism

  2020cites this paper
• Mitochondrial acyl carrier protein (ACP) at the interface of metabolic state sensing and mitochondrial function.

  2019cites this paper
• The emerging role of the mitochondrial fatty-acid synthase (mtFASII) in the regulation of energy metabolism.

  2019cites this paper
• Respiratory deficiency in yeast mevalonate kinase deficient may explain MKD-associate metabolic disorder in humans

  2018cites this paper
• Impact of Mitochondrial Fatty Acid Synthesis on Mitochondrial Biogenesis.

  2018cites this paper
• Characterization of a Drosophila model for Chorea‐Acanthocytosis

  2017cites this paper
• Characterization of a Drosophila model for Chorea‐Acanthocytosis

  2017cites this paper
• The Assembly Pathway of Mitochondrial Respiratory Chain Complex I.

  2017cites this paper
• Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.

  2017cites this paper
• Functional diversity of complex I subunits in Candida albicans mitochondria

  2016cites this paper
• Altering the Mitochondrial Fatty Acid Synthesis (mtFASII) Pathway Modulates Cellular Metabolic States and Bioactive Lipid Profiles as Revealed by Metabolomic Profiling

  2016cites this paper
• Eukaryotic LYR Proteins Interact with Mitochondrial Protein Complexes

  2015cites this paper
• The mitochondrial complex I of trypanosomatids - an overview of current knowledge

  2014cites this paper
• Accessory subunits of mitochondrial complex I.

  2013cites this paper
• The mitochondrial fatty acid synthesis (mtFASII) pathway is capable of mediating nuclear-mitochondrial cross talk through the PPAR system of transcriptional activation.

  2013cites this paper
• Structural insights into cofactor recognition of yeast mitochondria 3‐oxoacyl‐ACP reductase OAR1

  2013cites this paper
• Characterization of Bacterial Complex I (NDH-1) by a Genetic Engineering Approach

  2012cites this paper
• Brain, blood, and iron: perspectives on the roles of erythrocytes and iron in neurodegeneration.

  2012cites this paper
• A Structural Perspective on Respiratory Complex I

  2012cites this paper
• Chapter 11 Complexes I in the Green Lineage

  2012cites this paper
• Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs.

  2012cites this paper
• Complexes I in the green lineage.

  2012cites this paper
• Functional analysis of a mitochondrial phosphopantetheinyl transferase (PPTase) gene pptB in Aspergillus fumigatus.

  2011cites this paper
• Catalytic core of respiratory chain NADH-ubiquinone oxidoreductase : roles of the ND1, ND6 and ND4L subunits and mitochondrial disease modelling in Escherichia coli

  2011cites this paper
• Pathways for phospholipid deacylation in Saccharomyces cerevisiae and their impact on fatty acid trafficking and equilibrium

  2011cites this paper
• Mitochondria and Respiration

  2010cites this paper
• Estudo da Regulação da Expressão do Sintase de Ácidos Gordos de Saccharomyces cerevisiae na Aquisição de Resistência ao Peróxido de Hidrogénio

  2010cites this paper
• Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.

  2010cites this paper
• Mitochondrial fatty acid synthesis and respiration.

  2010cites this paper
• Characterization of two different acyl carrier proteins in complex I from Yarrowia lipolytica.

  2010cites this paper
• Mitochondrial respiratory complex I: structure, function and implication in human diseases.

  2009cites this paper
• Phylogenomics of the oxidative phosphorylation in fungi reveals extensive gene duplication followed by functional divergence

  2009cites this paper
• A C. elegans Model for Mitochondrial Fatty Acid Synthase II: The Longevity-Associated Gene W09H1.5/mecr-1 Encodes a 2-trans-Enoyl-Thioester Reductase

  2009cites this paper
• 17β‐Hydroxysteroid dehydrogenase type 8 and carbonyl reductase type 4 assemble as a ketoacyl reductase of human mitochondrial FAS

  2009cites this paper
• Myocardial Overexpression of Mecr, a Gene of Mitochondrial FAS II Leads to Cardiac Dysfunction in Mouse

  2009cites this paper
• Down-regulation of Mitochondrial Acyl Carrier Protein in Mammalian Cells Compromises Protein Lipoylation and Respiratory Complex I and Results in Cell Death*

  2009cites this paper
• Structural enzymological studies of 2-enoyl thioester reductase of the human mitochondrial FAS II pathway: new insights into its substrate recognition properties.

  2008cites this paper
• Function of Heterologous Mycobacterium tuberculosis InhA, a Type 2 Fatty Acid Synthase Enzyme Involved in Extending C20 Fatty Acids to C60-to-C90 Mycolic Acids, during De Novo Lipoic Acid Synthesis in Saccharomyces cerevisiae

  2008cites this paper
• Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei

  2008influential citation
• Lipoic Acid Biosynthesis

  2008cites this paper
• Characterization of the 2-enoyl thioester reductase of mitochondrial fatty acid synthesis type II in mammals

  2008cites this paper
• Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process

  2008cites this paper
• Fatty acid synthesis and elongation in yeast.

  2007cites this paper
• Human mitochondrial complex I assembly: a dynamic and versatile process.

  2007cites this paper
• Mitochondrial Fatty Acid Synthesis in Trypanosoma brucei*

  2007cites this paper
• Characterization of 3-hydroxyacyl-ACP dehydratase of mitochondrial fatty acid synthesis in yeast, humans and trypanosomes

  2007cites this paper
• Coupling of the de Novo Fatty Acid Biosynthesis and Lipoylation Pathways in Mammalian Mitochondria*

  2007cites this paper
• Mitochondrial acyl carrier proteins in Arabidopsis thaliana are predominantly soluble matrix proteins and none can be confirmed as subunits of respiratory Complex I

  2007cites this paper
• Energy converting NADH:quinone oxidoreductase (complex I).

  2006cites this paper
• Mitochondrial complex I: Structure, function and pathology

  2006cites this paper
• Genetic causes of mitochondrial complex I deficiency in children

  2006cites this paper
• Enoyl thioester reductases—enzymes of fatty acid synthesis and degradation in mitochondria

  2006influential citation
• Untersuchungen zum Protein-Koimport von Katalase A in Peroxisomen und Mitochondrien in der Hefe Saccharomyces cerevisiae

  2006cites this paper
• Tracing the evolution of a large protein complex in the eukaryotes, NADH:ubiquinone oxidoreductase (Complex I).

  2005cites this paper
• Altered Neuronal Mitochondrial Coenzyme A Synthesis in Neurodegeneration with Brain Iron Accumulation Caused by Abnormal Processing, Stability, and Catalytic Activity of Mutant Pantothenate Kinase 2

  2005cites this paper
• Composition of complex I from Neurospora crassa and disruption of two "accessory" subunits.

  2005cites this paper
• Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. Complementation of the yeast CEM1 knock-out strain.

  2005cites this paper
• Identification of variant molecules of Bacillus thermoproteolyticus ferredoxin: crystal structure reveals bound coenzyme A and an unexpected [3Fe-4S] cluster associated with a canonical [4Fe-4S] ligand motif.

  2005cites this paper
• Isolationsverfahren für den peripheren Arm des Atmungsketten-Komplex I aus Neurospora crassa

  2005cites this paper
• Mitochondrial fatty acid synthesis and maintenance of respiratory competent mitochondria in yeast.

  2005cites this paper
• Htd2p/Yhr067p is a yeast 3‐hydroxyacyl‐ACP dehydratase essential for mitochondrial function and morphology

  2004cites this paper
• Molecular genetics of complex I-deficient Chinese hamster cell lines.

  2004cites this paper
• The Human OXPHOS System

  2004cites this paper
• Identification and Molecular Characterization of the β-Ketoacyl-[Acyl Carrier Protein] Synthase Component of the Arabidopsis Mitochondrial Fatty Acid Synthase*

  2004cites this paper
• Lipids and membranes

  2004cites this paper
• Identification and molecular characterization of the beta-ketoacyl-[acyl carrier protein] synthase component of the Arabidopsis mitochondrial fatty acid synthase.

  2004cites this paper
• The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase).

  2004cites this paper
• Structure-function analysis of enoyl thioester reductase involved in mitochondrial maintenance.

  2003cites this paper
• The nuclear encoded subunits of complex I from bovine heart mitochondria.

  2003cites this paper
• The npgA/cfwA gene encodes a putative 4'-phosphopantetheinyl transferase which is essential for penicillin biosynthesis in Aspergillus nidulans

  2003cites this paper
• Nonorganellar Acyl Carrier Protein from Oleaginous Yeast Is a Homologue of Ribosomal Protein P2*

  2003cites this paper
• Characterization of 2-Enoyl Thioester Reductase from Mammals

  2003cites this paper
• Characterization of mitochondrial 2-enoyl thioester reductase involved in respiratory competence

  2003cites this paper
• Cloning, Expression, and Characterization of a Human 4′-Phosphopantetheinyl Transferase with Broad Substrate Specificity*

  2003cites this paper
• The proton-translocating NADH-quinone oxidoreductase in the respiratory chain: the secret unlocked.

  2003cites this paper
• Cloning, Expression, Characterization, and Interaction of Two Components of a Human Mitochondrial Fatty Acid Synthase

  2003cites this paper
• From NADH to ubiquinone in Neurospora mitochondria.

  2002cites this paper
• Effect of anoxia/reperfusion on the reversible active/de-active transition of NADH-ubiquinone oxidoreductase (complex I) in rat heart.

  2002cites this paper
• A century of mitochondrial research: achievements and perspectives.

  2001cites this paper
• Biogenesis of Respiratory Complex I

  2001cites this paper
• On Complex I and Other NADH:Ubiquinone Reductases of Neurospora crassa Mitochondria

  2001cites this paper
• Mitochondria make a come back.

  2001cites this paper
• Molecular Genetics of the Mammalian NADH–Ubiquinone Oxidoreductase

  2001cites this paper
• Candida tropicalis Etr1p andSaccharomyces cerevisiae Ybr026p (Mrf1′p), 2-Enoyl Thioester Reductases Essential for Mitochondrial Respiratory Competence

  2001cites this paper
• Maintenance and Integrity of the Mitochondrial Genome: a Plethora of Nuclear Genes in the Budding Yeast

  2000cites this paper
• Respiratory chain complex I is essential for sexual development in neurospora and binding of iron sulfur clusters are required for enzyme assembly.

  2000cites this paper