Organogenesis: Molecular Mechanisms Of Tubulogenesis

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Nature reviews genetics

• Publication date

  2002-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nrg840PMID 12094229
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo.

  2002cited by this paper
• Developmental control of blood cell migration by the Drosophila VEGF pathway.

  2002cited by this paper
• Patterning of angiogenesis in the zebrafish embryo.

  2002cited by this paper
• Organogenesis: Coordinating early kidney development: lessons from gene targeting

  2002cited by this paper
• The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos

  2002cited by this paper
• The plakin Short Stop and the RhoA GTPase are required for E-cadherin-dependent apical surface remodeling during tracheal tube fusion.

  2002cited by this paper
• It takes guts: the Drosophila hindgut as a model system for organogenesis.

  2002cited by this paper
• The ubiquitin ligase Hyperplastic discs negatively regulates hedgehog and decapentaplegic expression by independent mechanisms

  2002cited by this paper
• Cardiovascular biology: Creating unique blood vessels

  2001cited by this paper
• Positional cloning of heart and soul reveals multiple roles for PKCλ in zebrafish organogenesis

  2001cited by this paper
• A Signaling Adapter Function for 6 4 Integrin in the Control of HGF-Dependent Invasive Growth

  2001cited by this paper
• The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration.

  2001cited by this paper
• ribbon encodes a novel BTB/POZ protein required for directed cell migration in Drosophila melanogaster.

  2001cited by this paper
• Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly

  2001cited by this paper
• The α6β4 integrin and epithelial cell migration

  2001cited by this paper
• The Caenorhabditis elegans homolog of FGD1, the human Cdc42 GEF gene responsible for faciogenital dysplasia, is critical for excretory cell morphogenesis.

  2001cited by this paper
• Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

  2001cited by this paper
• Intercellular junctions and cellular polarity: the PAR-aPKC complex, a conserved core cassette playing fundamental roles in cell polarity.

  2001influential reference
• The alpha 6 beta 4 integrin and epithelial cell migration.

  2001cited by this paper
• Coupling Met to specific pathways results in distinct developmental outcomes.

  2001cited by this paper
• Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene

  2001cited by this paper
• The Drosophila ribbon gene encodes a nuclear BTB domain protein that promotes epithelial migration and morphogenesis.

  2001cited by this paper
• Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells.

  2001cited by this paper
• Induction of Pancreatic Differentiation by Signals from Blood Vessels

  2001cited by this paper
• Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development.

  2001cited by this paper
• PDZ proteins and polarity: functions from the fly.

  2001cited by this paper
• Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization.

  2001cited by this paper
• Gridlock signalling pathway fashions the first embryonic artery

  2001cited by this paper
• Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney.

  2001cited by this paper
• Organ formation in Drosophila: Specification and morphogenesis of the salivary gland

  2001cited by this paper
• Liver Organogenesis Promoted by Endothelial Cells Prior to Vascular Function

  2001cited by this paper
• Changes in adhesive properties of epithelial cells during early morphogenesis of the mammary gland

  2001cited by this paper
• Differential MAPK Pathways Utilized for HGF- and EGF-dependent Renal Epithelial Morphogenesis*

  2001cited by this paper
• Identification of an angiogenic mitogen selective for endocrine gland endothelium

  2001cited by this paper
• Signaling pathways in mammary gland development.

  2001cited by this paper
• Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis.

  2001cited by this paper
• A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth.

  2001cited by this paper
• Towards a cellular and molecular understanding of neurulation

  2001cited by this paper
• A putative GDP–GTP exchange factor is required for development of the excretory cell in Caenorhabditis elegans

  2001cited by this paper
• Time-lapse observation of branching morphogenesis of the lung bud epithelium in mesenchyme-free culture and its relationship with the localization of actin filaments.

  2000cited by this paper
• Genetic control of epithelial tube size in the Drosophila tracheal system.

  2000cited by this paper
• Multiple Forces Contribute to Cell Sheet Morphogenesis for Dorsal Closure in Drosophila

  2000cited by this paper
• Vascular-specific growth factors and blood vessel formation

  2000cited by this paper
• Organ shape in the Drosophila salivary gland is controlled by regulated, sequential internalization of the primordia.

  2000cited by this paper
• The receptor tyrosine kinase EphB4 and ephrin-B ligands restrict angiogenic growth of embryonic veins in Xenopus laevis.

  2000cited by this paper
• Control of epithelial cell shape and polarity.

  2000cited by this paper
• Oncogenic Raf-1 Disrupts Epithelial Tight Junctions via Downregulation of Occludin

  2000cited by this paper
• X-linked loci of Drosophila melanogaster causing defects in the morphology of the embryonic salivary glands

  2000cited by this paper
• Remodeling of desmosomal and hemidesmosomal adhesion systems during early morphogenesis of mouse pelage hair follicles.

  2000cited by this paper
• FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development.

  2000cited by this paper
• Fork head prevents apoptosis and promotes cell shape change during formation of the Drosophila salivary glands.

  2000cited by this paper
• Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis.

  2000cited by this paper
• Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung.

  2000cited by this paper
• Salivary gland development in Drosophila melanogaster.

  2000cited by this paper
• The molecular basis of lung morphogenesis.

  2000cited by this paper
• Activated R-Ras, Rac1, Pi 3-Kinase and Pkcε Can Each Restore Cell Spreading Inhibited by Isolated Integrin β1 Cytoplasmic Domains

  2000cited by this paper
• Vasculogenesis in the day 6.5 to 9.5 mouse embryo.

  2000cited by this paper
• RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the alpha(v)beta(3) and alpha(5)beta(1) integrins.

  2000cited by this paper
• Drawing lines in the Drosophila wing: initiation of wing vein development.

  2000cited by this paper
• RGD-Dependent Vacuolation and Lumen Formation Observed during Endothelial Cell Morphogenesis in Three-Dimensional Fibrin Matrices Involves the αvβ3 and α5β1 Integrins

  2000cited by this paper
• A requirement for neuropilin-1 in embryonic vessel formation.

  1999cited by this paper
• The dorsal-open group gene raw is required for restricted DJNK signaling during closure.

  1999cited by this paper
• ribbon, raw, and zipper have distinct functions in reshaping the Drosophila cytoskeleton

  1999cited by this paper
• Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

  1999cited by this paper
• The fourth dimension of life: fractal geometry and allometric scaling of organisms.

  1999influential reference
• Expression of green fluorescent protein in the ureteric bud of transgenic mice: a new tool for the analysis of ureteric bud morphogenesis.

  1999cited by this paper
• Cystic canal mutants in Caenorhabditis elegans are defective in the apical membrane domain of the renal (excretory) cell.

  1999cited by this paper
• Oxygen regulation of airway branching in Drosophila is mediated by branchless FGF.

  1999cited by this paper
• Genetic control of branching morphogenesis.

  1999cited by this paper
• Molecular and biological properties of vascular endothelial growth factor

  1999cited by this paper
• A mouse model for hereditary thyroid dysgenesis and cleft palate

  1998cited by this paper
• Bud formation precedes the appearance of differential cell proliferation during branching morphogenesis of mouse lung epithelium in vitro

  1998cited by this paper
• Sonic hedgehog is essential to foregut development

  1998cited by this paper
• VEGF mediates angioblast migration during development of the dorsal aorta in Xenopus.

  1998cited by this paper
• Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis.

  1998cited by this paper
• A correlation between epithelial proliferation rates, basement membrane component localization patterns, and morphogenetic potential in the embryonic mouse lung.

  1998cited by this paper
• Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

  1998cited by this paper
• Cardiovascular failure in mouse embryos deficient in VEGF receptor-3.

  1998cited by this paper
• sma-1 encodes a betaH-spectrin homolog required for Caenorhabditis elegans morphogenesis.

  1998cited by this paper
• Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia

  1998cited by this paper
• TAL1/SCL is expressed in endothelial progenitor cells/angioblasts and defines a dorsal-to-ventral gradient of vasculogenesis.

  1997cited by this paper
• Mechanisms of angiogenesis

  1997cited by this paper
• Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development.

  1997cited by this paper
• Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor Escargot.

  1996cited by this paper
• Zygotic Drosophila E-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo.

  1996cited by this paper
• An 11-Amino Acid Sequence from c-met Initiates Epithelial Chemotaxis via Phosphatidylinositol 3-Kinase and Phospholipase C (*)

  1996cited by this paper
• branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching.

  1996cited by this paper
• Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

  1996cited by this paper
• Mouse embryonic submandibular gland epithelium loses its tissue integrity during early branching morphogenesis

  1996cited by this paper
• Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

  1995cited by this paper
• Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

  1995cited by this paper
• A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation.

  1994cited by this paper
• Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor.

  1994cited by this paper
• flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors.

  1993cited by this paper
• Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.

  1993cited by this paper
• Lumen formation in the developing mouse mammary gland.

  1983cited by this paper
• Intimate cell contacts at the epithelial/mesenchymal interface in embryonic mouse lung.

  1976cited by this paper
• Development in DROSOPHILA MELANOGASTER.

  1927cited by this paper
• J Am Soc Nephrol 12: 2673–2682, 2001 Temporally Compartmentalized Expression of Ephrin-B2 during Renal Glomerular Development

  year unknowncited by this paper

• Real-time imaging reveals new mechanisms for pancreatic ductal establishment and remodeling.

  2026cites this paper
• The dynamics of tubulogenesis in development and disease.

  2025cites this paper
• Plasma proteins and rheumatoid arthritis: A Mendelian randomization analysis

  2025cites this paper
• The Enigmas of Tissue Closure: Inspiration from Drosophila

  2024cites this paper
• SOX9 switch links regeneration to fibrosis at the single-cell level in mammalian kidneys

  2024cites this paper
• The ion channel Anoctamin 10/TMEM16K coordinates organ morphogenesis across scales in the urochordate notochord

  2024cites this paper
• 4D pathology: translating dynamic epithelial tubulogenesis to prostate cancer pathology

  2024cites this paper
• Molecular regulators of defective placental and cardiovascular development in fetal growth restriction

  2024cites this paper
• Targeted therapy approaches for epithelial-mesenchymal transition in triple negative breast cancer

  2024cites this paper
• Systematic Analysis of Smooth Muscle and Cartilage Ring Formation during Mouse Tracheal Tubulogenesis

  2023cites this paper
• Anoctamin 10/TMEM16K mediates convergent extension and tubulogenesis during notochord formation in the early chordate Ciona intestinalis

  2023cites this paper
• Proteomic Profiling and Tumor Microenvironment Characterization Reveal Molecular and Immunological Hallmarks of Left-Sided and Right-Sided Colon Cancer Tumorigenesis.

  2023cites this paper
• Finishing the egg.

  2023cites this paper
• Modeling Polarity-Driven Laminar Patterns in Bilayer Tissues with Mixed Signaling Mechanisms

  2023cites this paper
• Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell

  2023cites this paper
• Zebrafish as a Model of Cardiac Pathology and Toxicity: Spotlight on Uremic Toxins

  2023cites this paper
• Autophagy, not apoptosis, plays a role in lumen formation of eccrine gland organoids

  2022cites this paper
• Molecular mechanisms of tubulogenesis revealed in the sea star hydro-vascular organ

  2022influential citation
• Deciphering the interplay between autophagy and polarity in epithelial tubulogenesis.

  2022cites this paper
• Genetic Variants in ARHGEF6 Cause Congenital Anomalies of the Kidneys and Urinary Tract in Humans, Mice, and Frogs

  2022cites this paper
• Computational approaches for simulating luminogenesis.

  2022cites this paper
• Hedgehog regulation of epithelial cell state and morphogenesis in the larynx

  2022cites this paper
• The Epithelial-to Mesenchymal Transition: Methods and Protocols

  2021cites this paper
• In Vivo Printing of Nanoenabled Scaffolds for the Treatment of Skeletal Muscle Injuries

  2021cites this paper
• Shaping the thyroid: from peninsula to de novo lumen formation.

  2021cites this paper
• Epithelial morphogenesis, tubulogenesis and forces in organogenesis.

  2021cites this paper
• Methods to Generate Tube Micropatterns for Epithelial Morphogenetic Analyses and Tissue Engineering.

  2021cites this paper
• The Role of NLRP3 Inflammasome Activation in the Epithelial to Mesenchymal Transition Process During the Fibrosis

  2020cites this paper
• Extracellular matrix dynamics in tubulogenesis.

  2020cites this paper
• Detecting new allies: Modifier screen identifies a genetic interaction between Imaginal disc growth factor 3 and a Rho-kinase substrate during dorsal appendage tube formation in Drosophila

  2020cites this paper
• Transcriptional landscape of the embryonic chicken Müllerian duct

  2020cites this paper
• Detecting New Allies: Modifier Screen Identifies a Genetic Interaction Between Imaginal disc growth factor 3 and combover, a Rho-kinase Substrate, During Dorsal Appendage Tube Formation in Drosophila

  2020cites this paper
• Mapping calcium dynamics in a developing tubular structure

  2020cites this paper
• Angiogenesis in gynecological cancers and the options for anti-angiogenesis therapy.

  2020cites this paper
• Fabrication of core-shell spheroids as building blocks for engineering 3D complex vascularized tissue.

  2019cites this paper
• Micropattern-based platform as a physiologically relevant model to study epithelial morphogenesis and nephrotoxicity.

  2019cites this paper
• Development and characterization of a biopolymer direct-write process for 3D microvascular structures formation.

  2019cites this paper
• FoxN1 mediates thymic cortex–medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis

  2019cites this paper
• Enhancement of HGF-induced tubulogenesis by endothelial cell-derived GDNF

  2019cites this paper
• Self-assembly, buckling and density-invariant growth of three-dimensional vascular networks

  2019cites this paper
• A tensile trilayered cytoskeletal endotube drives capillary-like lumenogenesis

  2019cites this paper
• Wnt/β‐catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating notch activity

  2018cites this paper
• Anisotropic Crb accumulation, modulated by Src42A, orients epithelial tube growth in Drosophila

  2018cites this paper
• Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis

  2018cites this paper
• Mesoscale physical principles of collective cell organization

  2018cites this paper
• Anisotropic Crb accumulation, modulated by Src42A, is coupled to polarised epithelial tube growth in Drosophila

  2018cites this paper
• Laminin-511: a key regulator of breast cancer metastasis

  2018cites this paper
• Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus

  2018cites this paper
• Mesoscale physical principles of collective cell organization

  2018cites this paper
• IN VITRO EVALUATION OF ANTICANCER EFFECT OF MOMORDICA BALSAMINA LINN . LEAF EXTRACT IN HUMAN BREAST MCF-7 CANCER CELLS by Itumeleng

  2017cites this paper
• Epithelial-mesenchymal transition in morphogenesis, cancer progression and angiogenesis.

  2017cites this paper
• Temporal regulation of epithelium formation mediated by FoxA, MKLP1, MgcRacGAP, and PAR-6

  2017cites this paper
• University of Birmingham N-ethyl-N-nitrosourea induced adaptor protein 2 sigma subunit 1 (Ap2s1) mutations establish Ap2s1 loss-of-function mice

  2017cites this paper
• Expression of Grhl 2 and Its Target Gene Products in Developing Mouse Submandibular Gland

  2017cites this paper
• Signaling Networks in Epithelial Tube Formation.

  2017cites this paper
• Proteomics Analysis Identifies Orthologs of Human Chitinase-Like Proteins as Inducers of Tube Morphogenesis Defects in Drosophila melanogaster

  2017cites this paper
• N‐ethyl‐N‐nitrosourea–Induced Adaptor Protein 2 Sigma Subunit 1 (Ap2s1) Mutations Establish Ap2s1 Loss‐of‐Function Mice

  2017cites this paper
• Cell behaviors and dynamics during angiogenesis

  2016cites this paper
• Epithelial Wnt/βcatenin signalling is essential for epididymal coiling.

  2016cites this paper
• Polygenic Causes of Congenital Diaphragmatic Hernia Produce Common Lung Pathologies.

  2016cites this paper
• In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation.

  2016cites this paper
• Mesenchymal Stromal Cells Epithelial Transition Induced by Renal Tubular Cells-Derived Extracellular Vesicles

  2016cites this paper
• Fonctions et régulations des protéines Crumbs dans la morphogenèse des tissus épithéliaux

  2016cites this paper
• Activation of pancreatic stellate cells involves an EMT-like process.

  2016influential citation
• Expression of Grhl2 and Its Target Gene Products in Developing Mouse Submandibular Gland

  2016cites this paper
• Functions of DDR1 in Epithelial Cell Differentiation

  2016cites this paper
• Temporal regulation of epithelium formation

  2016cites this paper
• Pulling together: Tissue-generated forces that drive lumen morphogenesis.

  2016cites this paper
• A Study On The Roles And Effects Of Syndecans On Endothelial Cell Biology During Angiogenesis

  2016cites this paper
• Temporal regulation of epithelium formation

  2016cites this paper
• ulling together : Tissue-generated forces that drive lumen orphogenesis

  2016cites this paper
• Apicobasal Polarity and Lumen Formation During Development

  2015cites this paper
• Spry2 regulates signalling dynamics and terminal bud branching behaviour during lung development.

  2015cites this paper
• Recent Advances in Elucidating the Genetic Mechanisms of Nephrogenesis Using Zebrafish

  2015cites this paper
• Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model.

  2015cites this paper
• Progenitor Epithelium

  2015cites this paper
• A new paradigm for animal symmetry

  2015influential citation
• FGF signalling in the control of craniofacial and tracheal gland development

  2015cites this paper
• Role of differential adhesion in cell cluster evolution: from vasculogenesis to cancer metastasis

  2015cites this paper
• PROGRAMA DE PÓS-GRADUAÇÃO EM GENÉTICA

  2015cites this paper
• Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation

  2014cites this paper
• An investigation into the role of OCRL1 in polarised epithelial cells

  2014cites this paper
• Fascin links Btl/FGFR signalling to the actin cytoskeleton during Drosophila tracheal morphogenesis

  2014cites this paper
• Design of growth factor sequestering biomaterials.

  2014cites this paper
• Hs3st3-modified heparan sulfate controls KIT+ progenitor expansion by regulating 3-O-sulfotransferases.

  2014cites this paper
• Development of the hemochorial maternal vascular spaces in the placenta through endothelial and vasculogenic mimicry.

  2014influential citation
• Effects of Na/K-ATPase and its ligands on bone marrow mesenchymal stem cell differentiation

  2014cites this paper
• Prostate cancer relevant antigens and enzymes for targeted drug delivery.

  2014cites this paper
• Effec ts of Na/K-ATPase and its ligands on bone marrow mesenchymal stem cell diffe rentiation

  2014cites this paper
• Vasculogenesis in Development

  2014cites this paper
• Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation

  2014cites this paper
• A comparative study of Pointed and Yan expression reveals new complexity to the transcriptional networks downstream of receptor tyrosine kinase signaling.

  2014cites this paper
• Cell and Developmental Biology

  2014cites this paper
• FGF10: Type III Epithelial Mesenchymal Transition and Invasion in Breast Cancer Cell Lines

  2014cites this paper
• Oral biosciences: The annual review 2013

  2014cites this paper
• Antiangiogenic activity and direct antitumor effect from a sulfated polysaccharide isolated from seaweed.

  2013cites this paper
• Btbd7/Cleftin regulates cleft formation and branching morphogenesis of epithelial cells

  2013cites this paper
• Extracellular matrix signaling in morphogenesis and repair.

  2013cites this paper
• Single primary fetal lung cells generate alveolar structures in vitro

  2013cites this paper
• In vivo imaging of Drosophila wing heart development during pupal stages.

  2013cites this paper