Role of Formins in Actin Assembly: Nucleation and Barbed-End Association

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Science

• Publication date

  2002-06-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1126/SCIENCE.1072309PMID 12052901
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Secretory vesicle transport velocity in living cells depends on the myosin-V lever arm length

  2002cited by this paper
• Yeast formins regulate cell polarity by controlling the assembly of actin cables

  2002cited by this paper
• Formins direct Arp2/3-independent actin filament assembly to polarize cell growth in yeast

  2002cited by this paper
• Actin cable dynamics in budding yeast

  2002cited by this paper
• Dynamic Localization and Function of Bni1p at the Sites of Directed Growth in Saccharomyces cerevisiae

  2001cited by this paper
• A Role for Actin, Cdc1p, and Myo2p in the Inheritance of Late Golgi Elements in Saccharomyces cerevisiae

  2001cited by this paper
• A role for Vps1p, actin, and the Myo2p motor in peroxisome abundance and inheritance in Saccharomyces cerevisiae

  2001cited by this paper
• Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins

  2000cited by this paper
• Molecular mechanisms controlling actin filament dynamics in nonmuscle cells.

  2000cited by this paper
• Genetic dissection of the budding yeast Arp2/3 complex: a comparison of the in vivo and structural roles of individual subunits.

  1999cited by this paper
• Stress fibres take shape

  1999cited by this paper
• Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex.

  1999cited by this paper
• Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region

  1999cited by this paper
• The Role of Actin in Spindle Orientation Changes during the Saccharomyces cerevisiae Cell Cycle

  1999cited by this paper
• Interaction of Bnr1p with a Novel Src Homology 3 Domain-containing Hof1p

  1998cited by this paper
• Three-dimensional imaging of the yeast actin cytoskeleton through the budding cell cycle.

  1998cited by this paper
• Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast.

  1998cited by this paper
• FH proteins as cytoskeletal organizers.

  1998cited by this paper
• Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis

  1997cited by this paper
• Bni1p and Bnr1p: downstream targets of the Rho family small G‐proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae

  1997cited by this paper
• Actin and myosin function in directed vacuole movement during cell division in Saccharomyces cerevisiae

  1996cited by this paper
• Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins.

  1996cited by this paper
• Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae.

  1996cited by this paper
• Cappuccino, a Drosophila maternal effect gene required for polarity of the egg and embryo, is related to the vertebrate limb deformity locus.

  1995cited by this paper
• Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene.

  1994cited by this paper
• Effects of CapZ, an actin capping protein of muscle, on the polymerization of actin.

  1989cited by this paper
• Microinjection of gelsolin into living cells

  1987cited by this paper
• Relationship of actin and tubulin distribution to bud growth in wild- type and morphogenetic-mutant Saccharomyces cerevisiae

  1984cited by this paper
• Cytochalasin D and platelet gelsolin accelerate actin polymer formation. A model for regulation of the extent of actin polymer formation in vivo.

  1982cited by this paper
• F actin assembly modulated by villin: Ca++-dependent nucleation and capping of the barbed end.

  1981cited by this paper
• A rapid assay for actin-associated high-affinity cytochalasin binding sites based on isoelectric precipitation of soluble protein.

  1980cited by this paper
• Mechanism of action of cytochalasin B on actin.

  1980cited by this paper

• Comprehensive Analysis of Formin Genes Reveals Their Roles in Tissue Development and Cold Stress Responses in Brassica rapa.

  2026cites this paper
• FHOD3 and DIAPH3 control cell migration and differentially shift the balance of parallel and perpendicular stress fibers

  2026cites this paper
• The cortical actin cytoskeleton and desmosomes act together in keratin filament network maintenance.

  2025cites this paper
• Genome-Wide Characterization and Analysis of the FH Gene Family in Medicago truncatula Under Abiotic Stresses

  2025cites this paper
• PPI network identifies interacting pathogenic signaling pathways in Candida albicans.

  2025cites this paper
• The Myo2 adaptor Ldm1 and its receptor Ldo16 mediate actin-dependent lipid droplet motility

  2025cites this paper
• The Sole Essential Low Molecular Weight Tropomyosin Isoform of Caenorhabditis elegans Is Essential for Pharyngeal Muscle Function

  2025cites this paper
• IntAct-U-ExM: Ultrastructure Expansion microscopy of actin networks via an internally-tagged actin

  2025cites this paper
• Control of plasma membrane-associated actin polymerization specifies the pattern of the cell wall in xylem vessels

  2025cites this paper
• Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

  2025cites this paper
• Hypoxia and the cytoskeleton.

  2025cites this paper
• Structural insights into actin filament turnover.

  2025cites this paper
• Mechanism of formin-mediated filament nucleation from profilin-actin

  2025cites this paper
• Actin filament assembly driven by distributive polymerases clustered on membrane surfaces

  2025cites this paper
• Endophilin–lamellipodin–VASP, key components in fast endophilin–mediated endocytosis, control actin polymerization within liquid-like condensates

  2025cites this paper
• A sperm–oocyte protein partnership required for egg activation in Caenorhabditis elegans

  2025cites this paper
• Impact of N-terminal dimerization on formin homology 1 domain polymer dynamics and actin assembly

  2025cites this paper
• Bni5 regulates and coordinates septin architecture and myosin-II functions at the cell division site

  2025cites this paper
• Renaissance at the actin filament pointed end: Mechanisms of assembly, capping and depolymerization.

  2025cites this paper
• Archaeal actins and the origin of a multi-functional cytoskeleton

  2024cites this paper
• Myosin-independent stiffness sensing by fibroblasts is regulated by the viscoelasticity of flowing actin

  2024cites this paper
• Molecular mechanism of actin filament elongation by formins

  2024cites this paper
• Applying Spatiotemporal Modeling of Cell Dynamics to Accelerate Drug Development.

  2024cites this paper
• Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα

  2024cites this paper
• Central Role of the Actomyosin Ring in Coordinating Cytokinesis Steps in Budding Yeast

  2024cites this paper
• The roles of yeast formins and their regulators Bud6 and Bil2 in the pheromone response

  2024cites this paper
• Current landscape of monogenic autoinflammatory actinopathies: A literature review.

  2024cites this paper
• FHOD-1 and profilin protect sarcomeres against contraction-induced deformation> in C. elegans

  2024cites this paper
• FHOD-1/profilin-mediated actin assembly protects sarcomeres against contraction-induced deformation in C. elegans

  2024cites this paper
• Genome-wide study reveals novel roles for formin-2 in axon regeneration as a microtubule dynamics regulator and therapeutic target for nerve repair.

  2023cites this paper
• CHLOROPLAST UNUSUAL POSITIONING 1 is a plant-specific actin polymerization factor regulating chloroplast movement.

  2023cites this paper
• Formin tails act as a switch, inhibiting or enhancing processive actin elongation

  2023cites this paper
• A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk

  2023cites this paper
• Cytochalasans and Their Impact on Actin Filament Remodeling

  2023cites this paper
• Multicomponent regulation of actin barbed end assembly by twinfilin, formin and capping protein

  2023cites this paper
• Genome-Wide Identification and Expression Profiling of the FORMIN Gene Family Implies Their Potential Functions in Abiotic Stress Tolerance in Rice (Oryza sativa)

  2023cites this paper
• Dual spatio-temporal regulation of axon growth and microtubule dynamics by RhoA signaling pathways

  2023cites this paper
• Actin- and microtubule-based motors contribute to clathrin-independent endocytosis in yeast

  2023cites this paper
• The role of SPIRE actin nucleators in cellular transport processes.

  2023cites this paper
• [Monogenic auto-inflammatory diseases associated with actinopathies: A review of the literature].

  2023cites this paper
• Evolutionary tuning of barbed end competition allows simultaneous construction of architecturally distinct actin structures

  2023cites this paper
• Effects of environmental stress factors on the actin cytoskeleton of fungi and plants: Ionizing radiation and ROS

  2023cites this paper
• The formins inhibitor SMIFH2 inhibits the cytoskeleton dynamics and mitochondrial function during goat oocyte maturation.

  2023cites this paper
• β-heavy-spectrin stabilizes the constricting contractile ring during cytokinesis

  2022cites this paper
• Large‐scale genetic screens identify BET‐1 as a cytoskeleton regulator promoting actin function and life span

  2022cites this paper
• OsFH13, a type I formin, is indispensable for rice morphogenesis

  2022cites this paper
• A structural model of the profilin–formin pacemaker system for actin filament elongation

  2022cites this paper
• REPS2 downregulation facilitates FGF-induced adhesion and migration in human lens epithelial cells through FAK/Cdc42 signaling and contributes to posterior capsule opacification.

  2022cites this paper
• Actin networks modulate heterogenous NF-κB dynamics in response to TNFα

  2022cites this paper
• Actin turnover protects the cytokinetic contractile ring from structural instability

  2022cites this paper
• The Actin Regulators Involved in the Function and Related Diseases of Lymphocytes

  2022cites this paper
• Dual control of formin-nucleated actin assembly by the chromatin and ER in mouse oocytes.

  2022cites this paper
• Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin health and lifespan

  2022cites this paper
• The branching code: A model of actin-driven dendrite arborization.

  2022cites this paper
• Actin networks modulate heterogenous NF-κ B dynamics in response to 1 TNF α 2

  2022cites this paper
• Title Rho signaling research: history, current status and future directions

  2021cites this paper
• Heterologous expression of human pro-inflammatory Caspase-1 in Saccharomyces cerevisiae and comparison to pro-apoptotic Caspase-8

  2021cites this paper
• Long non-coding RNAs bind to proteins relevant to the ethanol tolerance in yeast: a systems biology view

  2021cites this paper
• Polarisome assembly mediates actin remodeling during polarized yeast and fungal growth

  2021cites this paper
• CYK-1/Formin activation in cortical RhoA signaling centers promotes organismal left–right symmetry breaking

  2021cites this paper
• Role of Actin Cytoskeleton in E-cadherin-Based Cell–Cell Adhesion Assembly and Maintenance

  2021cites this paper
• Genetic Neuropathy Due to Impairments in Mitochondrial Dynamics

  2021cites this paper
• Neisseria gonorrhoeae subverts formin-dependent actin polymerization to colonize human macrophages

  2021cites this paper
• Extracellular | Cell Migration

  2021cites this paper
• Cytoskeleton | Actin Organization

  2021cites this paper
• Nucleation limits the lengths of actin filaments assembled by formin.

  2021cites this paper
• Rho GTPase signalling networks in cancer cell transendothelial migration

  2021cites this paper
• RhoGTPase Signalling in Cancer Progression and Dissemination.

  2021cites this paper
• Plant biology: Plant formins roll out the welcome wagon for microbes.

  2021cites this paper
• Regulation of the Actin Cytoskeleton via Rho GTPase Signalling in Dictyostelium and Mammalian Cells: A Parallel Slalom

  2021cites this paper
• Mechanistic of Rac and Cdc42 synchronization at the cell edge by ARHGAP39-dependent signaling nodules and the impact on protrusion dynamics

  2021cites this paper
• FGF23—an established master regulator of phosphate metabolism

  2021cites this paper
• How to Move from Cell to Cell without Leaving the Intracellular Space: Lessons from Intracellular Parasites

  2021cites this paper
• Formin’s nucleation activity influences actin filament length

  2021cites this paper
• Formins control dynamics of F-actin in the central cell of Arabidopsis thaliana

  2021cites this paper
• The multiple roles of actin-binding proteins at invadopodia.

  2021cites this paper
• 100th Anniversary of Macromolecular Science Viewpoint: User's Guide to Supramolecular Peptide-Polymer Conjugates.

  2021cites this paper
• Heterologous Expression and Auto-Activation of Human Pro-Inflammatory Caspase-1 in Saccharomyces cerevisiae and Comparison to Caspase-8

  2021cites this paper
• Formins bridle and unleash their way through cytokinesis: a phragmoplast-centered view.

  2021cites this paper
• Formins play important role in Leishmania physiology by acting as cytosolic actin bundlers

  2021cites this paper
• How to Move from Cell to Cell without Leaving the Intracellular Space: Lessons from Intracellular Parasites

  2021cites this paper
• Rapid assembly of a polar network architecture drives efficient actomyosin contractility

  2020cites this paper
• ARP2/3-independent WAVE/SCAR pathway and class XI myosin control sperm nuclear migration in flowering plants.

  2020cites this paper
• DAAM2 Variants Cause Nephrotic Syndrome via Actin Dysregulation.

  2020cites this paper
• FHOD‐1 is the only formin in Caenorhabditis elegans that promotes striated muscle growth and Z‐line organization in a cell autonomous manner

  2020cites this paper
• POLArIS, a versatile probe for molecular orientation, revealed actin filaments associated with microtubule asters in early embryos

  2020cites this paper
• Morphological and functional characterization of host proteins during infections by actin-hijacking bacterial pathogens

  2020cites this paper
• The actin polymerization factor Diaphanous and the actin severing protein Flightless I collaborate to regulate sarcomere size.

  2020cites this paper
• The branching code: a model of actin-driven dendrite arborisation

  2020cites this paper
• FHOD formin and SRF promote striated muscle development through separate pathways in C. elegans

  2020cites this paper
• Profilin's Affinity for Formin Regulates the Availability of Filament Ends for Actin Monomer Binding.

  2020cites this paper
• When Actin is Not Actin’ Like It Should: A New Category of Distinct Primary Immunodeficiency Disorders

  2020cites this paper
• Actin regulators in cancer progression and metastases: From structure and function to cytoskeletal dynamics.

  2020cites this paper
• Profilin choreographs actin and microtubules in cells and cancer.

  2020influential citation
• FHOD-1 is the only formin in Caenorhabditis elegans that promotes striated muscle growth and Z-line organization in a cell autonomous manner

  2020cites this paper
• Regulation of Cdc42 for polarized growth in budding yeast

  2020cites this paper
• The actin networks of chytrid fungi reveal evolutionary loss of cytoskeletal complexity in the fungal kingdom

  2020cites this paper
• Macrophages Use Distinct Actin Regulators to Switch Engulfment Strategies and Ensure Phagocytic Plasticity In Vivo

  2020cites this paper
• The actin cytoskeleton orchestra in Entamoeba histolytica

  2020influential citation
• Revising the actin disassembly machinery : The role of GMF and twinfilin in turnover of dendritic actin arrays

  2020cites this paper