Ischemic tolerance in the brain: Endogenous adaptive machinery against ischemic stress

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Neuroscience Research

• Publication date

  2012-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/jnr.23005PMID 22302606
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Abstracts S43 O1-H3-4 Extracortical projection dependent dendritic alignment and synaptic transmission of connected pyramidal cells

  2018cited by this paper
• Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1‐dependent adenosine monophosphate–activated kinase pathway

  2011influential reference
• SIK2 is a key regulator for neuronal survival after ischemia via TORC1-CREB.

  2011cited by this paper
• Glial Cells Drive Preconditioning-Induced Blood-Brain Barrier Protection

  2011cited by this paper
• Repetitive hypoxia extends endogenous neurovascular protection for stroke

  2011cited by this paper
• A Signaling Cascade of Nuclear Calcium-CREB-ATF3 Activated by Synaptic NMDA Receptors Defines a Gene Repression Module That Protects against Extrasynaptic NMDA Receptor-Induced Neuronal Cell Death and Ischemic Brain Damage

  2011cited by this paper
• Remote Ischemic Limb Preconditioning After Subarachnoid Hemorrhage: A Phase Ib Study of Safety and Feasibility

  2011cited by this paper
• NCX1 Is a Novel Target Gene for Hypoxia-Inducible Factor-1 in Ischemic Brain Preconditioning

  2011cited by this paper
• Multiple Preconditioning Paradigms Converge on Interferon Regulatory Factor-Dependent Signaling to Promote Tolerance to Ischemic Brain Injury

  2011cited by this paper
• Remote Ischemic Preconditioning Protects the Brain Against Injury After Hypothermic Circulatory Arrest

  2011cited by this paper
• Remote Ischemic Preconditioning for Cerebral and Cardiac Protection During Carotid Endarterectomy: Results From a Pilot Randomized Clinical Trial

  2010cited by this paper
• Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis.

  2010cited by this paper
• Activation of NR2A Receptors Induces Ischemic Tolerance through CREB Signaling

  2010influential reference
• Effects of AMP-Activated Protein Kinase in Cerebral Ischemia

  2010cited by this paper
• MicroRNAs Induced During Ischemic Preconditioning

  2010cited by this paper
• Ischemic Preconditioning Regulates Expression of microRNAs and a Predicted Target, MeCP2, in Mouse Cortex

  2010cited by this paper
• MicroRNAs as Effectors of Brain Function with Roles in Ischemia and Injury, Neuroprotection, and Neurodegeneration

  2010cited by this paper
• Hypoxic preconditioning suppresses group III secreted phospholipase A2‐induced apoptosis via JAK2‐STAT3 activation in cortical neurons

  2010cited by this paper
• Polycomb Group Proteins as Epigenetic Mediators of Neuroprotection in Ischemic Tolerance

  2010cited by this paper
• Ischemic pre‐conditioning alters cerebral microRNAs that are upstream to neuroprotective signaling pathways

  2010cited by this paper
• The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death

  2009cited by this paper
• Systemic Lipopolysaccharide Protects the Brain from Ischemic Injury by Reprogramming the Response of the Brain to Stroke: A Critical Role for IRF3

  2009cited by this paper
• VEGF-A/VEGFR-2 Signaling Leading to cAMP Response Element-Binding Protein Phosphorylation Is a Shared Pathway Underlying the Protective Effect of Preconditioning on Neurons and Endothelial Cells

  2009cited by this paper
• SUMOylation participates in induction of ischemic tolerance

  2009cited by this paper
• Hypoxic Preconditioning-Induced Cerebral Ischemic Tolerance: Role of Microvascular Sphingosine Kinase 2

  2009cited by this paper
• Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

  2009cited by this paper
• CREB activation in the rapid, intermediate, and delayed ischemic preconditioning against hypoxic–ischemia in neonatal rat

  2009cited by this paper
• Regulation of Glucose Transporter 3 Surface Expression by the AMP-Activated Protein Kinase Mediates Tolerance to Glutamate Excitation in Neurons

  2009cited by this paper
• Recombinant Human Erythropoietin in the Treatment of Acute Ischemic Stroke

  2009cited by this paper
• Toll‐like receptor 4 is involved in neuroprotection afforded by ischemic preconditioning

  2009cited by this paper
• Ambivalent Aspects of Interleukin-6 in Cerebral Ischemia: Inflammatory versus Neurotrophic Aspects

  2009influential reference
• Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use.

  2009cited by this paper
• Limb remote ischemic postconditioning protects against focal ischemia in rats.

  2009cited by this paper
• Deep Hypothermia Markedly Activates the Small Ubiquitin-Like Modifier Conjugation Pathway; Implications for the Fate of Cells Exposed to Transient Deep Hypothermic Cardiopulmonary Bypass

  2009cited by this paper
• Ischemic preconditioning-induced neuroprotection is associated with differential expression of IL-1beta and IL-1 receptor antagonist in the ischemic cortex.

  2009cited by this paper
• Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke

  2008cited by this paper
• Preconditioning Mediated by Sublethal Oxygen—Glucose Deprivation-Induced Cyclooxygenase-2 Expression via the Signal Transducers and Activators of Transcription 3 Phosphorylation

  2008influential reference
• The obligatory role of COX-2 expression for induction of HO-1 in ischemic preconditioned rat brain.

  2008influential reference
• Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons

  2008cited by this paper
• Differential Roles of NMDA Receptor Subtypes in Ischemic Neuronal Cell Death and Ischemic Tolerance

  2008cited by this paper
• In Vivo and In Vitro Characterization of a Novel Neuroprotective Strategy for Stroke: Ischemic Postconditioning

  2008cited by this paper
• Adrenomedullin protects neurons against oxygen glucose deprivation stress in an autocrine and paracrine manner

  2008cited by this paper
• Induction of Immunologic Tolerance to Myelin Basic Protein Prevents Central Nervous System Autoimmunity and Improves Outcome After Stroke

  2008cited by this paper
• Metabolic Downregulation: A Key to Successful Neuroprotection?

  2008cited by this paper
• Inhalational anesthetics as preconditioning agents in ischemic brain.

  2008cited by this paper
• Ubiquitin–Proteasome-Mediated Synaptic Reorganization: A Novel Mechanism Underlying Rapid Ischemic Tolerance

  2008cited by this paper
• Resveratrol and ischemic preconditioning in the brain.

  2008cited by this paper
• In Vivo and In Vitro Characterization of a Novel Neuroprotective Strategy for Stroke: Ischemic Postconditioning

  2008cited by this paper
• Toll-Like Receptor 9: A New Target of Ischemic Preconditioning in the Brain

  2008cited by this paper
• Ischemic Preconditioning Reveals that GLT1/EAAT2 Glutamate Transporter is a Novel PPARγ Target Gene Involved in Neuroprotection

  2007cited by this paper
• Pharmacological Induction of Ischemic Tolerance by Glutamate Transporter-1 (EAAT2) Upregulation

  2007cited by this paper
• Neuroprotective Effects of Adenosine Monophosphate-Activated Protein Kinase Inhibition and Gene Deletion in Stroke

  2007cited by this paper
• Preconditioning Reprograms the Response to Ischemic Injury and Primes the Emergence of Unique Endogenous Neuroprotective Phenotypes: A Speculative Synthesis

  2007cited by this paper
• Oxygen Sensing : Life and Death of a Cell Hypoxic preconditioning protects human brain endothelium from ischemic apoptosis by Akt-dependent survivin activation

  2007cited by this paper
• Neuron-Specific Inactivation of the Hypoxia Inducible Factor 1α Increases Brain Injury in a Mouse Model of Transient Focal Cerebral Ischemia

  2007cited by this paper
• Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase.

  2007cited by this paper
• The Upregulation of Glial Glutamate Transporter-1 Participates in the Induction of Brain Ischemic Tolerance in Rats

  2007cited by this paper
• CREB and cAMP response element‐mediated gene expression in the ischemic brain

  2007cited by this paper
• Prolonged and intermittent normobaric hyperoxia induce different degrees of ischemic tolerance in rat brain tissue.

  2007cited by this paper
• Neurovascular Protection by Ischemic Tolerance: Role of Nitric Oxide and Reactive Oxygen Species

  2007cited by this paper
• Protein SUMOylation is Massively Increased in Hibernation Torpor and is Critical for the Cytoprotection Provided by Ischemic Preconditioning and Hypothermia in SHSY5Y Cells

  2007cited by this paper
• Killer Proteases and Little Strokes—How the Things that do not Kill You Make You Stronger

  2007cited by this paper
• Resveratrol Mimics Ischemic Preconditioning in the Brain

  2006cited by this paper
• CBF Changes Associated with Focal Ischemic Preconditioning in the Spontaneously Hypertensive Rat

  2006cited by this paper
• Rapid Degradation of Bim by the Ubiquitin-Proteasome Pathway Mediates Short-term Ischemic Tolerance in Cultured Neurons*

  2006cited by this paper
• Interrupting Reperfusion as a Stroke Therapy: Ischemic Postconditioning Reduces Infarct Size after Focal Ischemia in Rats

  2006cited by this paper
• Cerebral preconditioning and ischaemic tolerance

  2006cited by this paper
• Neuroprotective Effects of Preconditioning Ischemia on Ischemic Brain Injury through Down-regulating Activation of JNK1/2 via N-Methyl-D-aspartate Receptor-mediated Akt1 Activation*

  2005cited by this paper
• CREB-Mediated Bcl-2 Protein Expression after Ischemic Preconditioning

  2005cited by this paper
• Ischemic preconditioning prevents protein aggregation after transient cerebral ischemia.

  2005cited by this paper
• SUMO: a history of modification.

  2005cited by this paper
• TNFR1 Upregulation Mediates Tolerance after Brain Ischemic Preconditioning

  2005cited by this paper
• Brain-Specific Knock-Out of Hypoxia-Inducible Factor-1α Reduces Rather Than Increases Hypoxic-Ischemic Damage

  2005cited by this paper
• Genome-Wide Gene Expression Analysis for Induced Ischemic Tolerance and Delayed Neuronal Death following Transient Global Ischemia in Rats

  2004cited by this paper
• Inhibition of Toll-like Receptor and Cytokine Signaling—A Unifying Theme in Ischemic Tolerance

  2004influential reference
• Localization of 70-kDa stress protein induction in gerbil brain after ischemia

  2004cited by this paper
• Transient Ischemic Attacks Before Ischemic Stroke: Preconditioning the Human Brain?: A Multicenter Magnetic Resonance Imaging Study

  2004cited by this paper
• Up-Regulation of Endothelial Nitric Oxide Synthase via Phosphatidylinositol 3-Kinase Pathway Contributes to Ischemic Tolerance in the CA1 Subfield of Gerbil Hippocampus

  2004cited by this paper
• Time Course and Cellular Distribution of Hsp27 and Hsp72 Stress Protein Expression in a Quantitative Gerbil Model of Ischemic Injury and Tolerance: Thresholds for Hsp72 Induction and Hilar Lesioning in the Context of Ischemic Preconditioning

  2004cited by this paper
• In Vitro Ischemic Tolerance Involves Upregulation of Glutamate Transport Partly Mediated by the TACE/ADAM17-Tumor Necrosis Factor-α Pathway

  2004influential reference
• Persistent inhibition of protein synthesis precedes delayed neuronal death in postischemic gerbil hippocampus

  2004cited by this paper
• cAMP response element‐binding protein activation in ligation preconditioning in neonatal brain

  2004cited by this paper
• Relevance of Transient Ischemic Attack to Early Neurological Recovery after Nonlacunar Ischemic Stroke

  2004influential reference
• Ischemic preconditioning and preinfarction angina in the clinical arena

  2004cited by this paper
• Putative endogenous mediators of preconditioning‐induced ischemic tolerance in rat brain identified by genomic and proteomic analysis

  2004cited by this paper
• Hypoxia‐induced ischemic tolerance in neonatal rat brain involves enhanced ERK1/2 signaling

  2004cited by this paper
• The release of tumor necrosis factor–α is associated with ischemic tolerance in human stroke

  2003cited by this paper
• CREB is required for acquisition of ischemic tolerance in gerbil hippocampal CA1 region

  2003cited by this paper
• The Protective Effects of Preconditioning on Cerebral Endothelial Cells in Vitro

  2003cited by this paper
• The glutamate and neutral amino acid transporter family: physiological and pharmacological implications.

  2003cited by this paper
• Mucosal tolerance to E-selectin provides cell-mediated protection against ischemic brain injury

  2003influential reference
• Functional Changes of Glial Glutamate Transporter GLT-1 during Ischemia: An In Vivo Study in the Hippocampal CA1 of Normal Mice and Mutant Mice Lacking GLT-1

  2003cited by this paper
• The release of tumor necrosis factor-alpha is associated with ischemic tolerance in human stroke.

  2003influential reference
• KATP channels and myocardial preconditioning: an update.

  2003cited by this paper
• Ischemic tolerance and endogenous neuroprotection.

  2003cited by this paper
• Copper/Zinc Superoxide Dismutase Attenuates Neuronal Cell Death by Preventing Extracellular Signal-Regulated Kinase Activation after Transient Focal Cerebral Ischemia in Mice

  2002cited by this paper
• Normobaric Hypoxia Induces Tolerance to Focal Permanent Cerebral Ischemia in Association with an Increased Expression of Hypoxia-Inducible Factor-1 and its Target Genes, Erythropoietin and VEGF, in the Adult Mouse Brain

  2002cited by this paper
• Neuroprotection by Hypoxic Preconditioning Requires Sequential Activation of Vascular Endothelial Growth Factor Receptor and Akt

  2002influential reference
• Upregulation of TACE/ADAM17 after Ischemic Preconditioning is Involved in Brain Tolerance

  2002cited by this paper
• Erythropoietin Is a Paracrine Mediator of Ischemic Tolerance in the Brain: Evidence from an In Vitro Model

  2002cited by this paper

• Remote ischemic preconditioning protects against spinal cord ischemia–reperfusion injury in mice by activating NMDAR/AMPK/PGC-1α/SIRT3 signaling

  2023cites this paper
• Plasma metabolomic profiling of patients with transient ischemic attack reveals positive role of neutrophils in ischemic tolerance

  2023cites this paper
• Concussive head injury exacerbates neuropathology of sleep deprivation: Superior neuroprotection by co-administration of TiO2-nanowired cerebrolysin, alpha-melanocyte-stimulating hormone, and mesenchymal stem cells.

  2020cites this paper
• Review Cerebral Ischemic Tolerance and Preconditioning: Methods, Mechanisms, Clinical Applications, and Challenges

  2020cites this paper
• Evolutionary concept of inflammatory response and stroke

  2020cites this paper
• Preconditioning Hippocampal Slices with Hypothermia Promotes Rapid Tolerance to Hypoxic Depolarization and Swelling: Mediation by Erythropoietin.

  2020cites this paper
• Leak ADAPTATION AND SENSITIZATION TO PROTEOTOXIC STRESS

  2019cites this paper
• Enhancing and Extending Biological Performance and Resilience

  2018cites this paper
• Non‐canonical activation of CREB mediates neuroprotection in a Caenorhabditis elegans model of excitotoxic necrosis

  2018cites this paper
• Non-Canonical Activation of CREB Mediates Neuroprotection in a C. elegans Model of Excitotoxic Necrosis

  2018cites this paper
• Ischemic Tolerance of the Spinal Cord

  2018cites this paper
• A Comparative Proteomics Approach to Identify Novel Therapeutic Targets in an Experimental Stroke Model

  2018cites this paper
• Conditioning Against the Pathology of Parkinson's disease.

  2018cites this paper
• Determination of Brain-Regional Blood Perfusion and Endogenous cPKCγ Impact on Ischemic Vulnerability of Mice with Global Ischemia

  2017cites this paper
• Neuroprotective effects of resveratrol against cerebral ischemia / reperfusion injury in rats through attenuation of inflammation

  2017cites this paper
• Nitropropionic acid-induced ischemia tolerance in the rat brain is mediated by reduced metabolic activity and cerebral blood

  2017cites this paper
• Ischemic Tolerance of the Brain and Spinal Cord: A Review

  2017cites this paper
• Novel Treatments in Neuroprotection for Aneurysmal Subarachnoid Hemorrhage

  2016cites this paper
• HspB5/αB-crystallin increases dendritic complexity and protects the dendritic arbor during heat shock in cultured rat hippocampal neurons

  2016cites this paper
• cPKC β-mediated phosphorylation inhibits CRMP 2 proteolysis and alleviates ischemic injury in 8 cultured cortical neurons and ischemic stroke-induced mice 9

  2016cites this paper
• Conventional protein kinase Cβ‐mediated phosphorylation inhibits collapsin response‐mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke‐induced mice

  2016cites this paper
• Recent Progress in Therapeutic Strategies for Ischemic Stroke

  2016cites this paper
• Perfil cognitivo de indivíduos com Acidente Vascular Encefálico (AVE) da artéria basilar na fase crônica

  2015cites this paper
• HspB5/αB-Crystallin in the Brain

  2015cites this paper
• A Novel Mouse Model of Subcortical Infarcts with Dementia

  2015cites this paper
• The Oxygen-Conserving Potential of the Trigeminocardiac Reflex

  2015cites this paper
• The adaptive and maladaptive continuum of stress responses – a hippocampal perspective

  2015cites this paper
• Hypoxic preconditioning and cell death from oxygen/glucose deprivation co-opt a subset of the unfolded protein response in hippocampal neurons.

  2015cites this paper
• Fetal asphyctic preconditioning protects against perinatal asphyxia- induced apoptosis and astrogliosis in neonatal brain.

  2015cites this paper
• Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury

  2014cites this paper
• 3-Nitropropionic Acid-Induced Ischemia Tolerance in the Rat Brain is Mediated by Reduced Metabolic Activity and Cerebral Blood Flow

  2014cites this paper
• N-acetyl cysteine prevents synergistic, severe toxicity from two hits of oxidative stress.

  2014cites this paper
• Adaptation and Sensitization to Proteotoxic Stress

  2014cites this paper
• Mn-SOD Upregulation by Electroacupuncture Attenuates Ischemic Oxidative Damage via CB1R-Mediated STAT3 Phosphorylation

  2014cites this paper
• Protein Redox Modification as a Cellular Defense Mechanism against Tissue Ischemic Injury

  2014cites this paper
• s-Methyl cysteine enhanced survival of nerve growth factor differentiated PC12 cells under hypoxic conditions.

  2014cites this paper
• Endogenous brain protection: what the cerebral transcriptome teaches us.

  2014cites this paper
• NMDA receptor antagonists MK-801 and memantine induce tolerance to oxygen and glucose deprivation in primary cultures of rat cerebellar granule cells.

  2014cites this paper
• The Mechanisms of Action of Domoic Acid: From Pathology to Physiology

  2014cites this paper
• Melatonin protects heart and brain

  2013cites this paper
• Improving Acute Stroke Management with CT Perfusion Imaging: Approaches to Treatment Guidance and Brain Tissue Salvage

  2013cites this paper
• A Program for Solving the Brain Ischemia Problem

  2013cites this paper
• Downregulation of miR‐181b in mouse brain following ischemic stroke induces neuroprotection against ischemic injury through targeting heat shock protein A5 and ubiquitin carboxyl‐terminal hydrolase isozyme L1

  2013cites this paper
• Alleviating brain stress: what alternative animal models have revealed about therapeutic targets for hypoxia and anoxia.

  2013cites this paper
• Autophagy Modulation in Disease Therapy: Where Do We Stand?

  2013cites this paper
• Bone morphogenetic protein-7 (BMP-7) mediates ischemic preconditioning-induced ischemic tolerance via attenuating apoptosis in rat brain.

  2013cites this paper
• Insight into hypoxic preconditioning and ischemic injury through determination of nPKCε-interacting proteins in mouse brain.

  2013cites this paper
• Transactions of the Royal Society of South Africa

  2013cites this paper
• Protein Oxidative Modifications: Beneficial Roles in Disease and Health.

  2013cites this paper
• Age-related reduction of cerebral ischemic preconditioning: myth or reality?

  2013cites this paper
• [CREB activation is a key player for ischemic tolerance in the brain].

  2012cites this paper
• Resveratrol preconditioning modulates inflammatory response in the rat hippocampus following global cerebral ischemia.

  2012cites this paper