Generation of a Mutant Infectious Bursal Disease Virus That Does Not Cause Bursal Lesions

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Journal of Virology

• Publication date

  1998-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.72.4.2647-2654.1998PMID 9525581PMCID PMC109706
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Three-dimensional structure of infectious bursal disease virus determined by electron cryomicroscopy

  1997cited by this paper
• VP5 of infectious bursal disease virus is not essential for viral replication in cell culture

  1997cited by this paper
• Age-Dependent Diarrhea Induced by a Rotaviral Nonstructural Glycoprotein

  1996cited by this paper
• Synthetic transcripts of double-stranded Birnavirus genome are infectious.

  1996influential reference
• Pathogenesis of wild-type and leaderless foot-and-mouth disease virus in cattle

  1996cited by this paper
• Identification of a novel viral protein in infectious bursal disease virus-infected cells.

  1995cited by this paper
• Identification of the active-site residues of the 3C proteinase of foot-and-mouth disease virus.

  1995cited by this paper
• The foot-and-mouth disease virus leader proteinase gene is not required for viral replication

  1995cited by this paper
• Molecular basis of antigenic variation in infectious bursal disease virus.

  1994cited by this paper
• A single chicken anemia virus protein induces apoptosis

  1994cited by this paper
• Active and passive protection against variant and classic infectious bursal disease virus strains induced by baculovirus-expressed structural proteins.

  1994cited by this paper
• Apoptosis induced by infectious bursal disease virus.

  1994cited by this paper
• Evidence for the detection of the infectious pancreatic necrosis virus polyprotein and the 17-kDa polypeptide in infected cells and of the NS protease in purified virus.

  1994cited by this paper
• Flow cytometric analysis of B cell and T cell subpopulations in specific-pathogen-free chickens infected with infectious bursal disease virus.

  1994cited by this paper
• Infectious bursal disease virus structural proteins expressed in a baculovirus recombinant confer protection in chickens.

  1993influential reference
• Demonstration of enzyme activities required for cap structure formation in infectious bursal disease virus, a member of the birnavirus group.

  1990cited by this paper
• Lack of pathogenicity of five serotype 2 infectious bursal disease viruses in chickens.

  1988cited by this paper
• Birnavirus precursor polyprotein is processed in Escherichia coli by its own virus-encoded polypeptide

  1988cited by this paper
• Biochemistry and immunology of infectious bursal disease virus.

  1988cited by this paper
• Properties of RNA polymerase activity associated with infectious bursal disease virus and characterization of its reaction products.

  1987cited by this paper
• Genomic structure of tbe large RNA segment of infectious bursal disease virus

  1986cited by this paper
• Genomic structure of the large RNA segment of infectious bursal disease virus.

  1986cited by this paper
• Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

  1983cited by this paper
• In vitro replication of infectious bursal disease virus in established lymphoid cell lines and chicken B lymphocytes

  1979cited by this paper
• Biophysical and biochemical characterization of five animal viruses with bisegmented double-stranded RNA genomes

  1979cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• Structural and growth characteristics of infectious bursal disease virus

  1976cited by this paper

• Deciphering the Natural Reassortment Dynamics of Infectious Bursal Disease Virus, Isolated from Field Outbreaks in Southern India, Through Complete Genome Sequencing

  2025cites this paper
• Advances in Infectious Bursal Disease Virus Vaccines—A Review

  2025cites this paper
• The History of Infectious Bursal Disease: The Second Period Between 1977 and 2005.

  2025cites this paper
• Establishment of minigenomes for infectious bursal disease virus

  2024cites this paper
• VRK2 inhibits the replication of infectious bursal disease virus by phosphorylating RACK1 and suppressing apoptosis.

  2024cites this paper
• Generation of a novel attenuated IBDV vaccine strain by mutation of critical amino acids in IBDV VP5.

  2024cites this paper
• Monoclonal antibody development and antigenic epitope identification of infectious bursal disease virus VP5.

  2024cites this paper
• An Infectious Bursal Disease Virus (IBDV) Reverse Genetics Rescue System and Neutralization Assay in Chicken B Cells

  2023cites this paper
• Whole Genome Sequencing of Infectious Bursal Disease Viruses Isolated from a Californian Outbreak Unravels the Underlying Virulence Markers and Highlights Positive Selection Incidence

  2023cites this paper
• Genetic Insight into the Interaction of IBDV with Host—A Clue to the Development of Novel IBDV Vaccines

  2023cites this paper
• Genomic Analysis of Infectious Bursal Disease Virus in Nigeria: Identification of Unique Mutations of Yet Unknown Biological Functions in Both Segments A and B

  2023cites this paper
• Avian immunosuppressive diseases and immune evasion

  2022cites this paper
• Infectious bursal disease virus’ interferences with host immune cells: what do we know?

  2022cites this paper
• Genetic Diversity of Recent Infectious Bursal Disease Viruses Isolated From Vaccinated Poultry Flocks in Malaysia

  2021cites this paper
• Six decades of infectious bursal disease in poultry: The journey so far and challenges ahead

  2021influential citation
• The Full Region of N-Terminal in Polymerase of IBDV Plays an Important Role in Viral Replication and Pathogenicity: Either Partial Region or Single Amino Acid V4I Substitution Does Not Completely Lead to the Virus Attenuation to Three-Yellow Chickens

  2021cites this paper
• Ex vivo rescue of recombinant very virulent IBDV using a RNA polymerase II driven system and primary chicken bursal cells

  2020cites this paper
• Reverse genetics approaches for live-attenuated vaccine development of infectious bursal disease virus.

  2020cites this paper
• Epigenetic Upregulation of Chicken MicroRNA-16-5p Expression in DF-1 Cells following Infection with Infectious Bursal Disease Virus (IBDV) Enhances IBDV-Induced Apoptosis and Viral Replication

  2019cites this paper
• Identification and assessment of virulence of a natural reassortant of infectious bursal disease virus

  2018cites this paper
• Structural and functional modeling of viral protein 5 of Infectious Bursal Disease Virus.

  2018cites this paper
• Exacerbated Apoptosis of Cells Infected with Infectious Bursal Disease Virus upon Exposure to Interferon Alpha

  2018cites this paper
• Adaptation, attenuation and molecular characterisation of very virulent infectious bursal disease virus for development of tissue culture-based attenuated and inactivated vaccines

  2018cites this paper
• Infectious Bursal Disease Virus-Host Interactions: Multifunctional Viral Proteins that Perform Multiple and Differing Jobs

  2017cites this paper
• VP2 of Infectious Bursal Disease Virus Induces Apoptosis via Triggering Oral Cancer Overexpressed 1 (ORAOV1) Protein Degradation

  2017influential citation
• Non-Lytic Egression of Infectious Bursal Disease Virus (IBDV) Particles from Infected Cells

  2017cites this paper
• Virucidal Properties of Bioceramic Derived from Chicken Feces pH 13 and its Stability in Harsh Environments

  2016cites this paper
• Genetic, antigenic and pathogenic characterization of four infectious bursal disease virus isolates from China suggests continued evolution of very virulent viruses.

  2015cites this paper
• Inhibition of infectious bursal disease virus transmission using bioceramic derived from chicken feces.

  2015cites this paper
• Molecular characterization of infectious bursal disease virus (IBDV) isolated in Argentina indicates a regional lineage

  2015cites this paper
• Infectious Bursal Disease Virus VP5 Polypeptide: A Phosphoinositide-Binding Protein Required for Efficient Cell-to-Cell Virus Dissemination

  2015cites this paper
• Cyclophilin A Interacts with Viral VP4 and Inhibits the Replication of Infectious Bursal Disease Virus

  2015cites this paper
• A reassortment vaccine candidate as the improved formulation to induce protection against very virulent infectious bursal disease virus.

  2014cites this paper
• Further evidence for the association of distinct amino acid residues with in vitro and in vivo growth of infectious bursal disease virus

  2014cites this paper
• THE ANTIVIRAL ROLES OF ATG1 IN DROSOPHILA MELANOGASTER: IMMUNE RESPONSES AGAINST DROSOPHILA X VIRUS

  2014cites this paper
• Recombinant infectious bursal disease virus expressing Newcastle disease virus (NDV) neutralizing epitope confers partial protection against virulent NDV challenge in chickens.

  2014cites this paper
• An in vivo experimental model to determine antigenic variations among infectious bursal disease viruses

  2013cites this paper
• VP4 : a putative protease encoded by infectious bursal disease virus.

  2013cites this paper
• Cellular uptake on N- and C-termini conjugated FITC of Rath cell penetrating peptides and its consequences for gene-expression profiling in U-937 human macrophages and HeLa cervical cancer cells

  2013cites this paper
• Avian Immunosuppressive Diseases and Immunoevasion

  2013cites this paper
• Critical Roles of Glucocorticoid-Induced Leucine Zipper in Infectious Bursal Disease Virus (IBDV)-Induced Suppression of Type I Interferon Expression and Enhancement of IBDV Growth in Host Cells via Interaction with VP4

  2012cites this paper
• Development of advanced molecular and biological methods for antigenic characterization of emerging variant infectious bursal disease viruses

  2012cites this paper
• An overview of infectious bursal disease

  2012cites this paper
• A one-step reverse transcription loop-mediated isothermal amplification for detection and discrimination of infectious bursal disease virus

  2011cites this paper
• Characterisation of infectious bursal disease virus (IBDV) polyprotein processing.

  2011cites this paper
• Critical Role for Voltage-Dependent Anion Channel 2 in Infectious Bursal Disease Virus-Induced Apoptosis in Host Cells via Interaction with VP5

  2011cites this paper
• Facteurs influençant la réponse immunitaire humorale suite à la vaccination avec un vaccin vivant contre la maladie de Gumboro chez le poulet de chair

  2011cites this paper
• PERSISTENCE, DISTRIBUTION AND IMMUNOPATHOGENESIS OF INFECTIOUS BURSAL DISEASE VIRUS IN CHICKENS

  2011cites this paper
• Infectious bursal disease virus activates the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway by interaction of VP5 protein with the p85α subunit of PI3K.

  2011cites this paper
• Comparison of the pathogenesis of infectious bursal disease virus (IBDV) in genetically different chickens after infection with virus strains of different virulence

  2010cites this paper
• The open reading frame 3 (ORF3) of porcine circovirus type 2 (PCV2) is dispensable for virus infection but evidence of reduced pathogenicity is limited in pigs infected by an ORF3-null PCV2 mutant.

  2010cites this paper
• VP5-deficient mutant virus induced protection against challenge with very virulent infectious bursal disease virus of chickens.

  2010cites this paper
• Sequence variability and evolution of the terminal overlapping VP5 gene of the infectious bursal disease virus

  2010cites this paper
• CHARACTERIZATION OF INFECTIOUS BURSAL DISEASE VIRUSES ISOLATED FROM COMMERCIAL CHICKENS

  2010cites this paper
• Recombinant Infectious Bursal Disease Virus Carrying Hepatitis C Virus Epitopes

  2010cites this paper
• Infectious bursal disease virus persistently infects bursal B-lymphoid DT40 cells.

  2009cites this paper
• Exchange of the VP5 of infectious bursal disease virus in a serotype I strain with that of a serotype II strain reduced the viral replication and cytotoxicity

  2009cites this paper
• Subcellular location and protein interactions of the infectious bronchitis virus gene 3 and 5 accessory proteins

  2009cites this paper
• Apoptosis induction by the 5′ NCR of infectious Bursal disease virus.

  2009cites this paper
• bursal disease virus persistently infects bursal B-lymphoid DT 40 cells

  2009cites this paper
• Aspectos determinantes en la presentación de la enfermedad infecciosa de la bursa

  2009cites this paper
• Naturally occurring mutations at residues 253 and 284 in VP2 contribute to the cell tropism and virulence of very virulent infectious bursal disease virus.

  2009cites this paper
• Molecular characterization of IPNV RNA replication intermediates during the viral infective cycle.

  2009cites this paper
• Attenuation of porcine circovirus 2 in SPF piglets by abrogation of ORF3 function.

  2009cites this paper
• The VP5 protein of infectious bursal disease virus promotes virion release from infected cells and is not involved in cell death

  2009cites this paper
• AVIAN IMMUNOSUPPRESSIVE DISEASES AND IMMUNE EVASION

  2008cites this paper
• Replication and packaging of an infectious bursal disease virus segment A-derived minigenome.

  2008cites this paper
• Presence of a Very Virulent Genotype of Infectious Bursal Disease Virus in Vaccinated Layer Hens in Turkey

  2007cites this paper
• Screening of differentially expressed transcripts in infectious bursal disease virus-induced apoptotic chicken embryonic fibroblasts by using cDNA microarrays.

  2007influential citation
• Genetic and Antigenic Characterization of Infectious Bursal Disease Viruses Isolated in Italy During the Period 2002–2005

  2007cites this paper
• Antigenic structure analysis of VP3 of infectious bursal disease virus.

  2007cites this paper
• Molecular mechanisms of porcine circovirus 2 replication and pathogenesis

  2007cites this paper
• Full-length sequence analysis of four IBDV strains with different pathogenicities

  2007cites this paper
• An improved method for infectious bursal disease virus rescue using RNA polymerase II system.

  2007cites this paper
• Molecular Detection and Differentiation of Infectious Bursal Disease Virus

  2007cites this paper
• Generation of VP5 deficient mutant of infectious bursal disease virus strain HZ2

  2006cites this paper
• Very virulent infectious bursal disease virus: reduced pathogenicity in a rare natural segment-B-reassorted isolate.

  2006influential citation
• Efficient expression of the 15-kDa form of infectious pancreatic necrosis virus VP5 by suppression of a UGA codon.

  2006cites this paper
• Changes in VP3 and VP5 genes during the attenuation of the very virulent infectious bursal disease virus strain Gx isolated in China

  2006cites this paper
• Nonstructural Protein of Infectious Bursal Disease Virus Inhibits Apoptosis at the Early Stage of Virus Infection

  2006cites this paper
• Reverse genetics systems of segmented double-stranded RNA viruses including rotavirus

  2006cites this paper
• The ORF3 Protein of Porcine Circovirus Type 2 Is Involved in Viral Pathogenesis In Vivo

  2006cites this paper
• Significance of the genetic relationships deduced from partial nucleotide sequencing of infectious bursal disease virus genome segments A or B

  2005cites this paper
• The Innate Immune Response of Drosophila melanogaster against the Birnavirus Drosophila X Virus.

  2005cites this paper
• Studies on infectious bursal disease virus

  2005cites this paper
• Infectious pancreatic necrosis virus induces apoptosis in vitro and in vivo independent of VP5 expression.

  2005cites this paper
• Avian adenovirus CELO recombinants expressing VP2 of infectious bursal disease virus induce protection against bursal disease in chickens.

  2004cites this paper
• Characterization of particles formed by the precursor protein VPX of infectious bursal disease virus in insect Hi-5 cells: implication on its proteolytic processing.

  2004cites this paper
• Base Usage and Dinucleotide Frequency of Infectious Bursal Disease Virus

  2004cites this paper
• Molecular characterization of Sp serotype strains of infectious pancreatic necrosis virus exhibiting differences in virulence.

  2004cites this paper
• Peptides resulting from the pVP2 C-terminal processing are present in infectious pancreatic necrosis virus particles.

  2004cites this paper
• VP1 protein of infectious bursal disease virus modulates the virulence in vivo.

  2004cites this paper
• Genome Assembly and Particle Maturation of the Birnavirus Infectious Pancreatic Necrosis Virus

  2004cites this paper
• A yeast two-hybrid search for candidate cellular proteins interacting with the infectious bursal disease virus proteins VP 1 , pVP 2 , VP 3 and VP 5

  2003cites this paper
• Plasmid DNA encoding antigens of infectious bursal disease viruses induce protective immune responses in chickens: factors influencing efficacy.

  2003cites this paper
• Homotypic interactions of the infectious bursal disease virus proteins VP3, pVP2, VP4, and VP5: mapping of the interacting domains.

  2003cites this paper
• bursal disease virus capsid protein VP 3 interacts both with VP 1 , the RNA-dependent RNA polymerase , and with viral double-stranded RNA

  2003cites this paper
• Molecular Interactions of theInfectious Bursal Disease Virus Proteins

  2003influential citation
• Identification and Molecular Characterization of the RNA Polymerase-Binding Motif of Infectious Bursal Disease Virus Inner Capsid Protein VP 3

  2003cites this paper
• Research on infectious bursal disease--the past, the present and the future.

  2003cites this paper