Rat glomerular mesangial cells synthesize basic fibroblast growth factor. Release, upregulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Journal of Clinical Investigation

• Publication date

  1992-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI116126PMID 1361494PMCID PMC443391
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mesangiolysis.

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• Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation

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• Mitogenic effect of platelet‐derived growth factor in human glomerular mesangial cells: modulation and/or suppression by inflammatory cytokines

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• Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.

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• Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor.

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