Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

K. Coppieters,F. Dotta,N. Amirian,Peter D. Campbell,T. Kay,M. Atkinson,B. Roep,M. V. von Herrath

Published 2012 in Journal of Experimental Medicine

ABSTRACT

In situ tetramer staining reveals the presence of islet antigen-reactive CD8+ T cells in pancreatic islets from deceased type 1 diabetes patients.

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