Methylation profiling in acute myeloid leukemia.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Blood

• Publication date

  2001-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/BLOOD.V97.9.2823PMID 11313277
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2000cited by this paper
• Aging, DNA methylation and cancer.

  1999influential reference
• Cancer-epigenetics comes of age

  1999influential reference
• A mammalian protein with specific demethylase activity for mCpG DNA

  1999cited by this paper
• CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.

  1999cited by this paper
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  1999cited by this paper
• Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia.

  1999cited by this paper
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  1999cited by this paper
• The Smad5 Gene Is Involved in the Intracellular Signaling Pathways That Mediate the Inhibitory Effects of Transforming Growth Factor-β on Human Hematopoiesis

  1998cited by this paper
• Hypomethylation status of CpG sites at the promoter region and overexpression of the human MDR1 gene in acute myeloid leukemias.

  1998cited by this paper
• Molecular genetics of human leukemia.

  1998cited by this paper
• DNA methylation differences associated with tumor tissues identified by genome scanning analysis.

  1998influential reference
• The Smad5 gene is involved in the intracellular signaling pathways that mediate the inhibitory effects of transforming growth factor-beta on human hematopoiesis.

  1998influential reference
• Increased DNA methyltransferase expression in leukaemia

  1998cited by this paper
• RNA and the epigenetic regulation of X chromosome inactivation.

  1998cited by this paper
• Alterations in DNA methylation: a fundamental aspect of neoplasia.

  1998cited by this paper
• The critical role of chromosome translocations in human leukemias.

  1998influential reference
• Association between CpG island methylation and microsatellite instability in colorectal cancer.

  1997cited by this paper
• Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1.

  1997cited by this paper
• HIC1 hypermethylation is a late event in hematopoietic neoplasms.

  1997cited by this paper
• Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study.

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• COBRA: a sensitive and quantitative DNA methylation assay.

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• The estrogen receptor CpG island is methylated in most hematopoietic neoplasms.

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• Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia.

  1994influential reference
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  1994influential reference
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