Suramin: with special reference to onchocerciasis.

No abstract is available for this paper.

• Publication year

  1978

• Venue

  Advances in pharmacology and chemotherapy

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/S1054-3589(08)60486-XPMID 358805
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interference with normal phagosome-lysosome fusion in macrophages, using ingested yeast cells and suramin

  1975cited by this paper
• Drug-induced lesions in trypanosome fine structure: a guide to modes of trypanocidal action.

  1975cited by this paper
• Drug effects on the fine structure of Trypanosoma rhodesiense: suramin, tryparsamide and mapharside.

  1974cited by this paper
• [Hereditary Quincke's edema. New therapeutic ways].

  1974cited by this paper
• In vitro transcription of kinetoplast and nuclear DNA in Kinetoplastida.

  1974cited by this paper
• Suramin: a potent inhibitor of the calcium transport in sarcoplasmic reticulum.

  1974cited by this paper
• Effects of suramin on complement, blood clotting, fibrinolysis and kinin formation

  1973cited by this paper
• Possible therapy in hereditary angioneurotic edema (HAE)

  1973cited by this paper
• Letter: Muscle cramps during maintenance haemodialysis.

  1973cited by this paper
• Suramin: a potent ATPase inhibitor which acts on the inside surface of the sodium pump.

  1973cited by this paper
• Onchocerciasis and Its Treatment

  1972cited by this paper
• Suramin induced amino-aciduria.

  1972cited by this paper
• Suramin--a potent reversible and competitive inhibitor of complement systems.

  1972cited by this paper
• Comparative properties of schistosomal and filarial dihydrofolate reductases.

  1972cited by this paper
• The effect of Trypan Blue, suramin and aurothiomalate on the breakdown of 125 I-labelled albumin within rat liver lysosomes.

  1971cited by this paper
• Chemotherapeutic studies on Litomosoides carinii infection of Mastomys natalensis. 3. The activity of drugs against adult parasites.

  1971cited by this paper
• Chemotherapeutic studies on Litomosoides carinii infection of Mastomys natalensis. 2. The activity of drugs against microfilariae.

  1971cited by this paper
• The effect of chemical agents on the turnover of the bound phosphate associated with the sodium-and-potassium ion-stimulated adenosine triphosphatase in ox brain microsomes.

  1970cited by this paper
• [Multiple drug treatment of pemphigus. Personal technic and results after 18-year follow-up].

  1970cited by this paper
• The African trypanosomiases

  1970cited by this paper
• Lysosomes and congenital malformations.

  1969cited by this paper
• Reinfections with Onchocerca volvulus in cured patients exposed to continuing transmission.

  1968cited by this paper
• The effect of suramin-phthalanilide complexes on the chemotherapeutic activity and toxicity of 4′,4″-bis (1,4,5,6-tetrahydro-2-pyrimidinyl)terephthalanilide (NSC 57153)

  1968cited by this paper
• Mycobacterium tuberculosis in Macrophages: Effect of Certain Surfactants and Other Membrane-Active Compounds

  1968cited by this paper
• Onchocerciasis.

  1968cited by this paper
• Experiments on the chemoprophylaxis of Onchocerca volvulus infection.

  1968cited by this paper
• The intake and transmissibility of Onchocerca volvulus microfilariae by Simulium damnosum fed on patients treated with Diethylcarbamazine, suramin or Mel W.

  1968cited by this paper
• O2-polarographic studies on soluble and mitochondrial enzymes of Crithidia fasciculata; glycerophosphage enzymes.

  1968cited by this paper
• The effects of drugs on Onchocerca volvulus. 3. Trials of suramin at different dosages and a comparison of the brands Antrypol, Moranyl and Naganol.

  1968cited by this paper
• Interaction of polyvinyl sulfate with ribosomes.

  1968cited by this paper
• Protein synthesis in cell-free preparation of Crithidia fasciculata.

  1968cited by this paper
• Effect of trypanocidal drugs on terminal respiration of Crithidia fasciculata.

  1968cited by this paper
• Zur Gehaltsbestimmung von Suramin‐Natrium. 10. Mitt. über die Bestimmung von pharmazeutischen Hilfsstoffen und Arzneistoffen

  1967cited by this paper
• [On the analysis of sodium suramine. 10. Report on the determination of pharmaceutic aids and drugs].

  1967cited by this paper
• The effects of antimicrobial agents on ribonucleic acid polymerase.

  1965cited by this paper
• OBSERVATIONS ON THE TREATMENT OF ONCHOCERCIASIS IN AN ENDEMIC AREA OF WESTERN NIGERIA.

  1964cited by this paper
• 5 – Chemotherapy of Trypanosomiasis

  1963cited by this paper
• ACTION OF DRUGS UPON TRYPANOSOMA CONGOLENSE, T. VIVAX AND T. RHODESIENSE IN TSETSE FLIES AND IN CULTURE.

  1963cited by this paper
• Non-Enzymatic Dissolution of Fibrin “s” by Acidic Dyes, Surfactants, and Naphthalene Sulfonates.∗

  1963cited by this paper
• The treatment of onchocerciasis.

  1960cited by this paper
• The effect of antifilarial drugs on the embryonic development of Litomosoides carinii, of the cotton-rat.

  1960cited by this paper
• The trypanocidal action of homidium, quinapyramine and suramin.

  1960cited by this paper
• Chaining and Unchaining Streptococcus faecalis—a Hypothesis of the Mechanism of Bacterial Cell Separation

  1958cited by this paper
• Comparison of the effect upon onchocerciasis of five drugs and selection of the one best able to prevent ocular complications.

  1958cited by this paper
• Failure of suramin (Bayer 205; germanin) to cause changes in the adrenal cortex of the rat.

  1958cited by this paper
• Suramin complexes. II. Prophylactic activity against Trypanosoma vivax in cattle.

  1957cited by this paper
• Observations on the chemotherapy of onchocerciasis in Bahr el Ghazal Province, Sudan.

  1957cited by this paper
• Inhibition of succinic dehydrogenase by polysulfonated compounds.

  1957cited by this paper
• Experimental treatment of Wuchereria bancrofti filariosis in French Oceania by suramin (naphuride sodium)

  1956cited by this paper
• Prophylactic Activity of Suramin Complexes in Animal Trypanosomiasis

  1956cited by this paper
• A preliminary report on the out-patient treatment of onchocerciasis with antrypol in the West Nile District of Uganda.

  1955cited by this paper
• TEXTBOOK OF GYNAECOLOGY

  1953cited by this paper
• Antrypol in the treatment of onchocerciasis.

  1952cited by this paper
• The inhibition of some pharmacological actions of pentamidine by suramin.

  1951cited by this paper
• Experimental therapy of onchocerciasis with suramin and hetrazan; results of a three-year study.

  1951cited by this paper
• Adrenal Insufficiency After Suramin Treatment of Pemphigus

  1950cited by this paper
• Chemotherapy of experimental filariasis.

  1950cited by this paper
• Studies on suramin (Antrypol: Bayer 205). 7. Further observations on the combination of the drug with proteins.

  1949cited by this paper
• Sleeping sickness of an unusual type in Sierra Leone and its attempted control.

  1948cited by this paper
• The estimation of suramin in plasma.

  1948cited by this paper
• The persistence in the blood stream of some compounds related to suramin.

  1948cited by this paper
• Studies on suramin (Antrypol: Bayer 205): 5. The combination of the drug with the plasma and other proteins.

  1946cited by this paper
• The adrenal glands in pemphigus vulgaris; report of six autopsies and review of the literature.

  1945cited by this paper
• Degeneration of the adrenal cortex produced by germanin.

  1941cited by this paper
• Concentration of Bayer 205 (Germanin) in Human Blood and Cerebrospinal Fluid after Treatment.

  1940cited by this paper
• Metabolic Studies on Patients with Pemphigus12

  1940cited by this paper
• Recent advances in chemotherapy

  1939cited by this paper
• Contribution on the Mode of Action of Germanin (Bayer 205)

  1939cited by this paper
• Studies on Bayer 205 (Germanin) and Antrypol: Further observations on the method of determination and on the retention of this drug in the animal body.

  1939cited by this paper
• Studies on Bayer 205 (Germanin) and Antrypol: The determination of small amounts of Bayer 205 (and Antrypol). II. The persistence of Bayer 205 in the blood stream after injection into animals.

  1938cited by this paper
• JUVENILE PEMPHIGUS: EFFECTS OF GERMANIN IN THREE CASES

  1938cited by this paper
• SIGNIFICANCE OF THE INCREASED FREQUENCY OF SELECTIVE CORTICAL NECROSIS OF ADRENAL: AS A CAUSE OF ADDISON'S DISEASE

  1937cited by this paper
• The action of “Bayer 205” on the tissues in fatal cases of kala-azar and trypanosomiasis

  1923cited by this paper
• Second Report on the Use of "Bayer 205" in Africa.

  1922cited by this paper

• Possible Interaction of Suramin with Thalamic P2X Receptors and NLRP3 Inflammasome Activation Alleviates Reserpine-Induced Fibromyalgia-Like Symptoms

  2025cites this paper
• Screening of Protein Tyrosine Phosphatase 1B Inhibitors from Actinomycete Extracts Using Recombinant Saccharomyces cerevisiae

  2025cites this paper
• β-enaminoester derivatives exhibit promising in vitro and in silico antiviral potential against Mayaro virus

  2024cites this paper
• Rearrangement of Arylsulfamates and Sulfates to Para-Sulfonyl Anilines and Phenols

  2024cites this paper
• Suramin Disturbs the Association of the N-Terminal Domain of SARS-CoV-2 Nucleocapsid Protein with RNA

  2023cites this paper
• Dual function of protein phosphatase 5 (PPP5C): An emerging therapeutic target for drug discovery.

  2023cites this paper
• Repurposing of Anti-Infectives for the Management of Onchocerciasis Using Machine Learning and Protein Docking Studies

  2023cites this paper
• HMM-based profiling identifies the binding to divalent cations and nucleotides as common denominators of suramin targets

  2023cites this paper
• Mechanism of inhibition of bacterial RNA helicases by diazo dyes and implications for antimicrobial drug development.

  2022cites this paper
• Suramin action in African trypanosomes involves a RuvB-like DNA helicase

  2022cites this paper
• In Silico Identification and Evaluation of Natural Products as Potential Tumor Necrosis Factor Function Inhibitors Using Advanced Enalos Asclepios KNIME Nodes

  2021cites this paper
• Targeted redesign of suramin analogs for novel antimicrobial lead development

  2021cites this paper
• Suramin Targets the Conserved Ligand-Binding Pocket of Human Raf1 Kinase Inhibitory Protein

  2021cites this paper
• Effects of single-dose antipurinergic therapy on behavioral and molecular alterations in the valproic acid-induced animal model of autism.

  2020cites this paper
• Suramin.

  2020cites this paper
• Pyruvate kinase from Plasmodium falciparum: Structural and kinetic insights into the allosteric mechanism.

  2020cites this paper
• Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection

  2020cites this paper
• Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37.

  2020cites this paper
• University of Groningen Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection Albulescu,

  2020cites this paper
• Structure‐Activity Relationship of NF023 Derivatives Binding to XIAP‐BIR1

  2019cites this paper
• Structure of XIAP-BIR1 V86E mutant

  2019cites this paper
• The cGAS-cGAMP-STING Pathway: A Molecular Link Between Immunity and Metabolism

  2019cites this paper
• Repurposing drugs for use against Zika virus infection$

  2018cites this paper
• Glucose Sensing in Trypanosoma brucei

  2018cites this paper
• Combination Anti-Leukimic Therapy by Utilizing Suramin and Biologic Response Modifiers

  2017cites this paper
• Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3

  2017cites this paper
• Low‐dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial

  2017cites this paper
• Two decades of antifilarial drug discovery: a review

  2017cites this paper
• nti fi larial drug discovery : a review

  2017cites this paper
• Antipurinergic therapy for autism-An in-depth review.

  2017cites this paper
• Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry

  2016cites this paper
• Potent inhibition of cyclic diadenylate monophosphate cyclase by the antiparasitic drug, suramin.

  2016cites this paper
• Structural Bases of Norovirus RNA Dependent RNA Polymerase Inhibition by Novel Suramin-Related Compounds

  2014cites this paper
• Suramin inhibits helicase activity of NS3 protein of dengue virus in a fluorescence-based high throughput assay format.

  2014cites this paper
• The anti-angiogenic activity of Artemisia herba-alba's essential oil and its relation with the harvest period

  2014cites this paper
• Postoperative adjuvant combination therapy with doxorubicin and noncytotoxic suramin in dogs with appendicular osteosarcoma.

  2014cites this paper
• A combination treatment with DNA methyltransferase inhibitors and suramin decreases invasiveness of breast cancer cells

  2014cites this paper
• Nucleotide signalling during inflammation

  2014cites this paper
• Discovery of highly potent TNFα inhibitors using virtual screen.

  2014cites this paper
• Glycotherapeutics: Clinical Implications

  2014cites this paper
• Delivery of Suramin as an Antiviral Agent through Liposomal Systems

  2014cites this paper
• Studies on acid phosphatases of Trypanosoma congolense.

  2013cites this paper
• standard trypanocides. DL-alpha-difluoromethylornithine and in mice using Trypanosoma brucei rhodesiense infections Combination chemotherapy of drug-resistant

  2013cites this paper
• SubstratesCofactors for Cleavage of Synthetic Human Complement Factor I Does Not

  2013cites this paper
• Small-molecule inhibitors of the interaction between TNF and TNFR.

  2013cites this paper
• Current Directions in Insulin-Like Growth Factor Research

  2013cites this paper
• Suramin is a Novel Activator of PP5 and Biphasically Modulates S100-Activated PP5 Activity

  2013cites this paper
• The Beneficial Effect of Suramin on Monocrotaline-Induced Pulmonary Hypertension in Rats

  2013cites this paper
• Chemoprevention and Novel Treatments of Non-Muscle Invasive Bladder Cancer

  2012cites this paper
• Suramin inhibits the growth of nasopharyngeal carcinoma cells via the downregulation of osteopontin.

  2012cites this paper
• Melarsoprol cyclodextrin inclusion complexes for the treatment for human African trypanosomiasis

  2011cites this paper
• The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site*

  2011cites this paper
• TRANSIENT WRIST AND ANKLE EDEMA, ERRATIC SKIN LESIONS AND EOSINOPHILIA SECONDARY TO LOIASIS

  2011cites this paper
• Agents Active against Parasites and Pneumocystis

  2010cites this paper
• The Effect of Subconjunctival Suramin on Corneal Neovascularization in Rabbits

  2010cites this paper
• Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancer

  2010cites this paper
• Translational Research: Using Suramin as a Platform

  2010cites this paper
• Role of iron in the proliferation of the established human tumor cell lines U-937 and K-562: effects of suramin and a lipophilic iron chelator (PIH).

  2009cites this paper
• A Novel Bioluminescent Protease Assay Using Engineered Firefly Luciferase

  2008cites this paper
• PACS-2 integrates interorganellar communication pathways of cellular homeostasis and apoptosis

  2008cites this paper
• Behandlung des metastasierten Nebennierenkarzinoms mit Suramin

  2008cites this paper
• In vitro effects of suramin on Trypanosoma cruzi.

  2008cites this paper
• Improved Muscle Healing after Contusion Injury by the Inhibitory Effect of Suramin on Myostatin, a Negative Regulator of Muscle Growth

  2008cites this paper
• Lysyl oxidase (LOX) mRNA expression and genes of the differentiated osteoblastic phenotype are upregulated in human osteosarcoma cells by suramin.

  2008cites this paper
• New Advances in Molecular Therapy for Muscle Repair After Diseases and Injuries

  2008cites this paper
• Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin.

  2007cites this paper
• Suramin Inhibits Not Only Tumor Growth and Metastasis but Also Angiogenesis in Experimental Pancreatic Cancer

  2007cites this paper
• Antifilarials and their mode of action.

  2007cites this paper
• Different ways to antiangiogenesis by angiostatin and suramin, and quantitation of angiostatin‐induced antiangiogenesis

  2007cites this paper
• Suramin inhibits bFGF-induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane

  2007cites this paper
• Stein Mechanisms of Action Suramin : A Novel Antineoplastic Agent with Multiple Potential Updated Version

  2006cites this paper
• Phase II Trial of Suramin in Patients with Advanced Renal Cell Carcinoma : Treatment Results , Pharmacokinetics , and Tumor Growth Factor Expression 1

  2006cites this paper
• Targeting the PTPome in human disease

  2006cites this paper
• Sustained phosphorylation of Bid is a marker for resistance to Fas-induced apoptosis during chronic liver diseases.

  2006cites this paper
• Inhibition by suramin of protein synthesis in vitro. Ribosomes as the target of the drug.

  2006cites this paper
• Basic fibroblast growth factor as a therapeutic target for chemosensitization in colorectal cancer.

  2006cites this paper
• Phase I evaluation of low-dose suramin as chemosensitizer of doxorubicin in dogs with naturally occurring cancers.

  2006cites this paper
• Suramin-induced reciprocal changes in glucose and lactate synthesis in renal tubules contribute to its hyperglycaemic action.

  2006cites this paper
• Antiproliferative Effects of Suramin on Lymphoid Cells1

  2006influential citation
• Recent developments in search of antifilarial agents.

  2006cites this paper
• Phase II Trial of Suramin in Patients with Advanced Renal Cell Carcinoma: Treatment Results, Pharmacokinetics, and Tumor Growth Factor Expression1

  2006cites this paper
• Nontoxic Suramin as a Chemosensitizer in Patients: Dosing Nomogram Development

  2006cites this paper
• Suramin interacts with RANK and inhibits RANKL-induced osteoclast differentiation.

  2005cites this paper
• Suramin inhibits tumor cell cytotoxicity mediated through natural killer cells, lymphokine-activated killer cells, monocytes, and tumor necrosis factor

  2005cites this paper
• The inhibitory effect caused by suramin on the paracrine growth of human cancer cells and fibroblasts

  2005cites this paper
• Molecular pharmacodynamics of chemotherapy: fibroblast growth factor (FGF) inhibitors as chemosensitizers

  2005cites this paper
• Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma

  2005cites this paper
• The Use of Suramin, an Antifibrotic Agent, to Improve Muscle Recovery after Strain Injury

  2005cites this paper
• Effective measures for controlling trypanosomiasis

  2005cites this paper
• Suramin: an anticancer drug with unique biological effects

  2004cites this paper
• Suramin Treatment for Onchocerciasis: Cost Analysis of a Kinetically Optimized Regimen and the Standard Regimen

  2004cites this paper
• Inhibition by suramin of the NADPH oxidase from horse polymorphonuclear leukocytes

  2004cites this paper
• Suramin Derivatives as Inhibitors and Activators of Protein-tyrosine Phosphatases*

  2004cites this paper
• SubstratesRequire Cofactors for Cleavage of Synthetic Human Complement Factor I Does Not

  2004cites this paper
• Human Complement Factor I Does Not Require Cofactors for Cleavage of Synthetic Substrates 1

  2004cites this paper
• [Effect of suramin on proliferation and migration of lens epithelial cells in vitro].

  2004cites this paper
• Thirty-month follow-up of sub-optimal responders to multiple treatments with ivermectin, in two onchocerciasis-endemic foci in Ghana

  2004cites this paper
• Chapter 4 Molecular Mechanisms Behind The Regulation Of Cell Cycle Progression In Cardiovascular System

  2004cites this paper
• Phase II Trial of Suramin in Patients with Metastatic Renal Cell Carcinoma

  2004cites this paper
• Effekt von Suramin auf Proliferation und Migration von Linsenepithelzellen in vitro

  2004cites this paper