The Cytochrome P450 Lanosterol 14α-Demethylase Gene Is a Demethylation Inhibitor Fungicide Resistance Determinant in Monilinia fructicola Field Isolates from Georgia

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Applied and Environmental Microbiology

• Publication date

  2007-11-16

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1128/AEM.02159-07PMID 18024679PMCID PMC2223246
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Instability of Propiconazole Resistance and Fitness in Monilinia fructicola.

  2007cited by this paper
• Agrobacterium T-DNA-mediated integration and gene replacement in the brown rot pathogen Monilinia fructicola

  2006cited by this paper
• Overexpression of the 14α-Demethylase Target Gene (CYP51) Mediates Fungicide Resistance in Blumeriella jaapii

  2006cited by this paper
• Inhibition of Efflux Transporter-Mediated Fungicide Resistance in Pyrenophora tritici-repentis by a Derivative of 4′-Hydroxyflavone and Enhancement of Fungicide Activity

  2005cited by this paper
• In vitro selection of sterol-biosynthesis-inhibitor (SBI)-resistant mutants in Monilinia fructicola (Wint.) Honey

  2005cited by this paper
• A Point Mutation in the 14α-Sterol Demethylase Gene cyp51A Contributes to Itraconazole Resistance in Aspergillus fumigatus

  2004cited by this paper
• Reduced Sensitivity in Monilinia fructicola to Propiconazole in Georgia and Implications for Disease Management.

  2004cited by this paper
• Mobile Genetic Elements in Mycelial Fungi

  2004cited by this paper
• Heterologous expression of the P450 sterol 14α-demethylase gene from Monilinia fructicola reduces sensitivity to some but not all DMI fungicides☆

  2004cited by this paper
• Transposable elements in filamentous fungi.

  2003cited by this paper
• Modulators of membrane drug transporters potentiate the activity of the DMI fungicide oxpoconazole against Botrytis cinerea.

  2003cited by this paper
• Cloning and expression analysis of the ATP-binding cassette transporter gene MFABC1 and the alternative oxidase gene MfAOX1 from Monilinia fructicola.

  2003cited by this paper
• A Point Mutation in the 14α-Sterol Demethylase Gene cyp51A Contributes to Itraconazole Resistance in Aspergillus fumigatus

  2003cited by this paper
• Identification and Characterization of Benzimidazole Resistance in Monilinia fructicola from Stone Fruit Orchards in California

  2003cited by this paper
• The 14alpha-Demethylasse(CYP51A1) Gene is Overexpressed in Venturia inaequalis Strains Resistant to Myclobutanil.

  2001cited by this paper
• Tandem Repeat of a Transcriptional Enhancer Upstream of the Sterol 14α-Demethylase Gene (CYP51) inPenicillium digitatum

  2000cited by this paper
• Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans.

  1999cited by this paper
• Resistance of Venturia inaequalis to the sterol biosynthesis-inhibiting fungicide, penconazole [1-(2-(2,4-dichlorophenyl) pentyl)-1H-1,2,4-triazole]

  1999cited by this paper
• Multiple amino acid substitutions in lanosterol 14alpha-demethylase contribute to azole resistance in Candida albicans.

  1999cited by this paper
• Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents

  1998cited by this paper
• A Novel ATP-Binding Cassette Transporter Involved in Multidrug Resistance in the Phytopathogenic FungusPenicillium digitatum

  1998cited by this paper
• PCR cloning and detection of point mutations in the eburicol 14a-demethylase (CYP51) gene from Erysiphe graminis f. sp. hordei, a “recalcitrant” fungus

  1998cited by this paper
• Molecular analysis of cyp51 from fluconazole-resistant Candida albicans strains.

  1997cited by this paper
• Molecular biological characterization of an azole-resistant Candida glabrata isolate

  1997cited by this paper
• Multidrug resistance in Aspergillus nidulans involves novel ATP-binding cassette transporters

  1997cited by this paper
• A mutation in the 14 alpha-demethylase gene of Uncinula necator that correlates with resistance to a sterol biosynthesis inhibitor

  1997cited by this paper
• An improved PCR method for walking in uncloned genomic DNA.

  1995cited by this paper
• Physiological implications of sterol biosynthesis in yeast.

  1995cited by this paper
• Lanosterol 14α-Demethylase (Cytochrome P45014DM)

  1993cited by this paper
• Multiple functions for sterols in Saccharomyces cerevisiae.

  1985cited by this paper

• G462S mutation and over-expression of AaCYP51 cause resistance to metconazole with cross-resistance to partial DMIs in Alternaria alternata on cherry.

  2026cites this paper
• Dual roles of the G462S mutation of AaCYP51 in regulating self-overexpression and DMI resistance in Alternaria alternata.

  2025cites this paper
• Unveiling the resistance risk and mechanism of mefentrifluconazole in Colletotrichum scovillei

  2025cites this paper
• Rise and Fall of Phytophthora infestans Resistance to Non-Specific Fungicide in Experimental Populations

  2025cites this paper
• Fungicide resistance in Fusarium species: exploring environmental impacts and sustainable management strategies

  2025cites this paper
• Distribution of propiconazole-resistant Geotrichum candidum in peach orchards with or without cull fruit amendments.

  2025cites this paper
• G462S substitution of AaCYP51 confers moderate resistance to tebuconazole in Alternaria alternata

  2025cites this paper
• Genetic Variation of Monilinia fructicola Population in Korea

  2024cites this paper
• Comparative fitness of Monilinia fructicola isolates with multiple fungicide-resistant phenotypes.

  2024cites this paper
• Visual detection of fungicide resistance by combining RPA and CRISPR/Cas12a in peach Brown rot fungus Monilinia fructicola.

  2024cites this paper
• Pseudomonas protegens volatile organic compounds inhibited brown rot of postharvest peach fruit by repressing the pathogenesis-related genes in Monilinia fructicola.

  2024cites this paper
• Propiconazole resistance phenotypes in Geotrichum candidum from South Carolina peaches are linked to point mutations in GcCYP51B gene.

  2024cites this paper
• Fungicide Sensitivity and Non-Target Site Resistance in Rhizoctonia zeae Isolates Collected from Corn and Soybean Fields in Nebraska.

  2024cites this paper
• Pyrrolnitrin in Pseudomonas chlororaphis strain AFS009 metabolites reduces constitutive and DMI-induced MfCYP51 gene expression in Monilinia fructicola.

  2024cites this paper
• The Mediator complex subunit MoMed15 plays an important role in conferring sensitivity to isoprothiolane by modulating xenobiotic metabolism in M. oryzae

  2024cites this paper
• Bioproducts of Pseudomonas chlororaphis suppress DMI fungicide-induced CsCYP51A and CsCYP51B gene expression in Colletotrichum siamense and generate synergistic effects with metconazole and propiconazole.

  2024cites this paper
• Pseudomonas chlororaphis metabolites reduce MfCYP51 expression and yield synergistic efficacy in mixture with reduced rates of propiconazole against DMI-resistant Monilinia fructicola isolates.

  2024cites this paper
• Mutations associated with fungicide resistance in Colletotrichum species: A Review

  2023cites this paper
• Re-evaluation of sensitivity of Monilinia fructicola isolates to the DMI fungicide propiconazole in the Southeastern United States and investigation of the genetic element Mona.

  2023cites this paper
• Sensitivity Baselines, Resistance Monitoring, and Molecular Mechanisms of the Rice False Smut Pathogen Ustilaginoidea virens to Prochloraz and Azoxystrobin in Four Regions of Southern China

  2023cites this paper
• Spray-induced gene silencing of SsOah1 and SsCyp51 confers protection to Nicotiana benthamiana and Brassica juncea against Sclerotinia sclerotiorum

  2023cites this paper
• Efficacy of calcium propionate against fungicide-resistant fungal plant pathogens and suppression of botrytis blight of ornamental flowers.

  2023cites this paper
• Identifying and controlling anthracnose caused by Colletotrichum taxa of Welsh onion in Sanxing, Taiwan.

  2023cites this paper
• Resistance risk assessment of mefentrifluconazole in Corynespora cassiicola and the control of cucumber target spot by a two-way mixture of mefentrifluconazole and prochloraz.

  2023cites this paper
• Resistance to the DMI fungicide mefentrifluconazole in Monilinia fructicola: risk assessment and resistance basis analysis.

  2023cites this paper
• Dose-Dependent Genetic Resistance to Azole Fungicides Found in the Apple Scab Pathogen

  2023cites this paper
• Molecular Mechanisms and Biological Characteristics of Botrytis cinerea Field Isolate Resistance to Pyrisoxazole in Liaoning Province.

  2023cites this paper
• Target and non-target site mechanisms of fungicide resistance and their implications for the management of crop pathogens.

  2023cites this paper
• Screening for Binding Partners and Protein-Protein Interactions of a Fungal Transcription Factor- XDR1

  2022cites this paper
• Global distribution and management of peach diseases

  2022cites this paper
• Sterol demethylation inhibitor fungicide resistance in Colletotrichum siamense from chili is caused by mutations in CYP51A and CYP51B

  2022influential citation
• Biochemical and molecular characterization of prochloraz resistance in Lasiodiplodia theobromae field isolates.

  2022cites this paper
• The Transcription Factor CsAtf1 Negatively Regulates the Cytochrome P450 Gene CsCyp51G1 to Increase Fludioxonil Sensitivity in Colletotrichum siamense

  2022cites this paper
• Effects of Bacillus subtilis CF-3 volatile organic compounds on the transcriptome and proteome of Monilinia fructicola reveal a potential mechanism of action

  2022cites this paper
• Difference in ergosterol concentrations extracted from demethylation inhibitor resistant and susceptible strains of Monilinia fructicola: understanding the ‘Mona’ element

  2021cites this paper
• Molecular Mechanisms Underlying Fungicide Resistance in Citrus Postharvest Green Mold

  2021cites this paper
• Population structure of Pyrenophora teres f. teres barley pathogens from different continents.

  2021cites this paper
• Lack of an intron in cytochrome b and overexpression of sterol 14α-demethylase indicate a potential risk for QoI and DMI resistance development in Neophysopella spp. on grapes.

  2021cites this paper
• Securing fruit production: Opportunities from the elucidation of the molecular mechanisms of postharvest fungal infections.

  2021cites this paper
• Non-Target Site Mechanisms of Fungicide Resistance in Crop Pathogens: A Review

  2021cites this paper
• Multiple resistance to DMI, QoI and SDHI fungicides in field isolates of Phakopsora pachyrhizi

  2021cites this paper
• Analysis of the prochloraz-Mn resistance risk and its molecular basis in Mycogone rosea from Agaricus bisporus.

  2021cites this paper
• Sensitivity of C. fructicola and C. siamense of peach in China to multiple classes of fungicides and characterization of pyraclostrobin-resistant isolates.

  2021cites this paper
• Point Mutations in FgSdhC2 or in the 5' Untranslated Region of FgSdhC1 Confer Resistance to a Novel Succinate Dehydrogenase Inhibitor Flubeneteram in Fusarium graminearum.

  2021cites this paper
• Evidence for the Role of CYP51A and Xenobiotic Detoxification in Differential Sensitivity to Azole Fungicides in Boxwood Blight Pathogens

  2021cites this paper
• Molecular Characterization of Laboratory Mutants of Fusarium oxysporum f. sp. niveum Resistant to Prothioconazole, a Demethylation Inhibitor (DMI) Fungicide

  2021cites this paper
• Fungicide effects on human fungal pathogens: Cross-resistance to medical drugs and beyond

  2021cites this paper
• Parallel evolution of multiple mechanisms for demethylase inhibitor fungicide resistance in the barley pathogen Pyrenophora teres f. sp. maculata.

  2020cites this paper
• Mutations and Overexpression of CYP51 Associated with DMI-Resistance in Colletotrichum gloeosporioides from Chili.

  2020cites this paper
• Three-Locus Sequence Identification and Differential Tebuconazole Sensitivity Suggest Novel Fusarium equiseti Haplotype from Trinidad

  2020cites this paper
• Comparisons between genetic diversity, virulence and colony morphology of Monilinia fructicola and Monilinia laxa isolates

  2020cites this paper
• Significance of 195 bp-enhancer of PdCYP51B in the acquisition of Penicillium digitatum DMI resistance and increase of fungal virulence.

  2020cites this paper
• Cross-Resistance Among Demethylation Inhibitor Fungicides With Brazilian Monilinia fructicola Isolates as a Foundation to Discuss Brown Rot Control in Stone Fruit.

  2020cites this paper
• Overexpression of three P450 genes is responsible for resistance to novel pyrimidine amines in Magnaporthe oryzae.

  2020cites this paper
• Survey and genetic analysis of demethylation inhibitor fungicide resistance in Monilinia fructicola from Michigan orchards.

  2020cites this paper
• Monitoring and analysis of rice pathogen Ustilaginoidea virens isolates with resistance to sterol demethylation inhibitors in China

  2020cites this paper
• Cross-resistance to the new fungicide mefentrifluconazole in DMI-resistant fungal pathogens.

  2020cites this paper
• Baseline sensitivity and action mechanism of the sterol demethylation inhibitor flusilazole to Valsa mali.

  2020cites this paper
• Sensitivity of Pyricularia oryzae Populations to Fungicides Over a 26-Year Time Frame in Brazil.

  2020cites this paper
• 3D Pharmacophore-based Ligand Alignment, Virtual Screening and Molecular Docking Protocols Towards the Discovery of 2-((1H-1,2,4-triazol-1- yl)methyl) Derivatives as Antifungal Inhibitors

  2020cites this paper
• Characterization of difenoconazole resistance in Lasiodiplodia theobromae from papaya in Brazil.

  2020cites this paper
• Survival Cost and Diverse Molecular Mechanisms of Magnaporthe oryzae Isolate Resistance to Epoxiconazole.

  2020cites this paper
• Characterization of propiconazole field-resistant isolates of Ustilaginoidea virens.

  2019cites this paper
• Induced expression of CYP51 associated with difenoconazole resistance in the pathogenic Alternaria sect. on potato in China.

  2019cites this paper
• A genome resource for several North American Venturia inaequalis isolates with multiple fungicide resistance phenotypes.

  2019cites this paper
• On the nature, symptoms and genetic diversity of Monilinia isolates and their viruses in Western Australia

  2019cites this paper
• The design and synthesis of Novel AOX and cytochrome bc1 complex inhibitors which act as phytopathogenic fungicides

  2019cites this paper
• Discontinuance of tebuconazole in the field restores sensitivity ofMonilinia fructicolain stone fruit orchards

  2019cites this paper
• atrB-Associated Fludioxonil Resistance in Botrytis fragariae Not Linked to Mutations in Transcription Factor mrr1.

  2019cites this paper
• Fitness Penalties in the Evolution of Fungicide Resistance.

  2018cites this paper
• Elevated MIC Values of Imidazole Drugs against Aspergillus fumigatus Isolates with TR34/L98H/S297T/F495I Mutation

  2018cites this paper
• Molecular and biological characteristics of laboratory metconazole-resistant mutants in Fusarium graminearum.

  2018cites this paper
• Monilinia fructicola and Monilinia laxa isolates from stone fruit orchards sprayed with fungicides displayed a broader range of responses to fungicides than those from unsprayed orchards

  2018influential citation
• LAMP detection of the genetic element 'Mona' associated with DMI resistance in Monilinia fructicola.

  2018cites this paper
• Fusarium graminearum ATP-Binding Cassette Transporter Gene FgABCC9 Is Required for Its Transportation of Salicylic Acid, Fungicide Resistance, Mycelial Growth and Pathogenicity towards Wheat

  2018cites this paper
• Triazole Resistance in Aspergillus Species: An Emerging Problem

  2017cites this paper
• Assessing the Risk for Resistance and Elucidating the Genetics of Colletotrichum truncatum That Is Only Sensitive to Some DMI Fungicides

  2017cites this paper
• Plasticity of the MFS1 Promoter Leads to Multidrug Resistance in the Wheat Pathogen Zymoseptoria tritici

  2017cites this paper
• Identification of two Monilia species from apricot in China

  2017cites this paper
• Molecular Tools for the Detection and Deduction of Azole Antifungal Drug Resistance Phenotypes in Aspergillus Species

  2017cites this paper
• Reduced sensitivity to azoxystrobin is stable in Monilinia fructicola isolates

  2017cites this paper
• The Point Mutation G461S in the MfCYP51 Gene is Associated with Tebuconazole Resistance in Monilinia fructicola Populations in Brazil.

  2017cites this paper
• Function of the genetic element 'Mona' associated with fungicide resistance in Monilinia fructicola.

  2017cites this paper
• Erratum to: Resistance of wheat pathogen Zymoseptoria tritici to DMI and QoI fungicides in the Nordic-Baltic region - a status

  2017cites this paper
• Resistance of wheat pathogen Zymoseptoria tritici to DMI and QoI fungicides in the Nordic-Baltic region - a status

  2017cites this paper
• Changes in the Sclerotinia sclerotiorum transcriptome during infection of Brassica napus

  2017influential citation
• Evaluation of berberine as a natural compound to inhibit peach brown rot pathogen Monilinia fructicola

  2017cites this paper
• Isolation and Characterization of Antifungal Metabolites from Pterocarpus santalinus against Fusarium graminearum Causing Fusarium Head Blight on Wheat

  2017cites this paper
• Overexpression of the CYP51A1 Gene and Repeated Elements are Associated with Differential Sensitivity to DMI Fungicides in Venturia inaequalis.

  2016cites this paper
• Co-Occurrence of Two Allelic Variants of CYP51 in Erysiphe necator and Their Correlation with Over-Expression for DMI Resistance

  2016cites this paper
• Sensitisation of an Azole-Resistant Aspergillus fumigatus Strain containing the Cyp51A-Related Mutation by Deleting the SrbA Gene

  2016cites this paper
• Sensitivity of Colletotrichum Species, Including C. fioriniae and C. nymphaeae, from Peach to Demethylation Inhibitor Fungicides.

  2016cites this paper
• Epidemiological and Genomic Landscape of Azole Resistance Mechanisms in Aspergillus Fungi

  2016cites this paper
• Effect of Fungicide Applications on Monilinia fructicola Population Diversity and Transposon Movement.

  2016cites this paper
• Fungicide resistance analysis of major tree fruit pathogens in Michigan

  2016cites this paper
• Stability of Resistance

  2015cites this paper
• A Novel Sterol Regulatory Element-Binding Protein Gene (sreA) Identified in Penicillium digitatum Is Required for Prochloraz Resistance, Full Virulence and erg11 (cyp51) Regulation

  2015cites this paper
• The evolution of fungicide resistance.

  2015cites this paper
• Mechanisms of Resistance to an Azole Fungicide in the Grapevine Powdery Mildew Fungus, Erysiphe necator.

  2015cites this paper
• Fungicide-induced transposon movement in Monilinia fructicola.

  2015cites this paper