Characterization of Klebsiella pneumoniae Type 1 Fimbriae by Detection of Phase Variation during Colonization and Infection and Impact on Virulence

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Infection and Immunity

• Publication date

  2008-06-16

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.00494-08PMID 18559432PMCID PMC2519443
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Utilization of an Intracellular Bacterial Community Pathway in Klebsiella pneumoniae Urinary Tract Infection and the Effects of FimK on Type 1 Pilus Expression

  2008cited by this paper
• The changing face of Klebsiella pneumoniae infections in the community.

  2007cited by this paper
• Yersiniabactin Is a Virulence Factor for Klebsiella pneumoniae during Pulmonary Infection

  2007cited by this paper
• Complex Interplay between Type 1 Fimbrial Expression and Flagellum-Mediated Motility of Uropathogenic Escherichia coli

  2007cited by this paper
• Demonstration of regulatory cross-talk between P fimbriae and type 1 fimbriae in uropathogenic Escherichia coli.

  2006cited by this paper
• Cyclic di-GMP as a second messenger.

  2006cited by this paper
• Identification of Klebsiella pneumoniae virulence determinants using an intranasal infection model

  2005cited by this paper
• Down-Regulation of the kps Region 1 Capsular Assembly Operon following Attachment of Escherichia coli Type 1 Fimbriae to d-Mannose Receptors

  2005cited by this paper
• Pyogenic Liver Abscess with a Focus on Klebsiella pneumoniae as a Primary Pathogen: An Emerging Disease with Unique Clinical Characteristics

  2005cited by this paper
• The Distinct Binding Specificities Exhibited by Enterobacterial Type 1 Fimbriae Are Determined by Their Fimbrial Shafts*

  2005cited by this paper
• Pathogenic potential of environmental Klebsiella pneumoniae isolates.

  2004cited by this paper
• The Klebsiella pneumoniae O Antigen Contributes to Bacteremia and Lethality during Murine Pneumonia

  2004cited by this paper
• Integrated regulatory responses of fimB to N-acetylneuraminic (sialic) acid and GlcNAc in Escherichia coli K-12.

  2004cited by this paper
• Application of a novel multi-screening signature-tagged mutagenesis assay for identification of Klebsiella pneumoniae genes essential in colonization and infection.

  2003cited by this paper
• The Product of the fimI Gene Is Necessary for Escherichia coli Type 1 Pilus Biosynthesis

  2003cited by this paper
• Role of capsule in Klebsiella pneumoniae virulence: lack of correlation between in vitro and in vivo studies.

  2003cited by this paper
• Distant cis‐active sequences and sialic acid control the expression of fimB in Escherichia coli K‐12

  2003cited by this paper
• Klebsiella pneumoniae type 3 pili facilitate adherence and biofilm formation on abiotic surfaces.

  2003cited by this paper
• A rapid and simple method for inactivating chromosomal genes in Yersinia.

  2003cited by this paper
• Klebsiella pneumoniae MrkD-mediated biofilm formation on extracellular matrix- and collagen-coated surfaces.

  2003cited by this paper
• Molecular Analysis of the Contribution of the Capsular Polysaccharide and the Lipopolysaccharide O Side Chain to the Virulence of Klebsiella pneumoniae in a Murine Model of Pneumonia

  2002cited by this paper
• Community-Acquired Klebsiella pneumoniae Bacteremia: Global Differences in Clinical Patterns

  2002cited by this paper
• Penicillin Pharmacodynamics in Four Experimental Pneumococcal Infection Models

  2001cited by this paper
• Type 3 Fimbrial Shaft (MrkA) of Klebsiella pneumoniae, but Not the Fimbrial Adhesin (MrkD), Facilitates Biofilm Formation

  2001cited by this paper
• Cloning and Sequencing of the Klebsiella pneumoniae O5wb Gene Cluster and Its Role in Pathogenesis

  2000cited by this paper
• One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.

  2000influential reference
• Development of a Long-Term Ascending Urinary Tract Infection Mouse Model for Antibiotic Treatment Studies

  2000cited by this paper
• Capsule Impedes Adhesion to and Invasion of Epithelial Cells by Klebsiella pneumoniae

  2000cited by this paper
• Pneumococcal pneumonia and bacteremia model in mice for the analysis of protective antibodies.

  2000cited by this paper
• In vivo phase variation of Escherichia coli type 1 fimbrial genes in women with urinary tract infection.

  1999cited by this paper
• Consequences of Reduction of Klebsiella pneumoniae Capsule Expression on Interactions of This Bacterium with Epithelial Cells

  1999cited by this paper
• In vivo detection of Escherichia coli type 1 fimbrial expression and phase variation during experimental urinary tract infection.

  1999cited by this paper
• Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin.

  1998cited by this paper
• Klebsiella spp. as Nosocomial Pathogens: Epidemiology, Taxonomy, Typing Methods, and Pathogenicity Factors

  1998cited by this paper
• Primary liver abscess due to Klebsiella pneumoniae in Taiwan.

  1998cited by this paper
• Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli.

  1998cited by this paper
• Invasion of cultured human epithelial cells by Klebsiella pneumoniae isolated from the urinary tract

  1997cited by this paper
• Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccination.

  1997cited by this paper
• Adhesive properties and antibiotic resistance of Klebsiella, Enterobacter, and Serratia clinical isolates involved in nosocomial infections

  1996cited by this paper
• Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract.

  1996cited by this paper
• Role of lipopolysaccharide in colonization of the mouse intestine by Salmonella typhimurium studied by in situ hybridization

  1996cited by this paper
• Type 1 fimbrial shafts of Escherichia coli and Klebsiella pneumoniae influence sugar-binding specificities of their FimH adhesins

  1994cited by this paper
• Escherichia coli F-18 phase locked 'on' for expression of type 1 fimbriae is a poor colonizer of the streptomycin-treated mouse large intestine.

  1993cited by this paper
• Serotypes, hemagglutinins, siderophore synthesis, and serum resistance of Klebsiella isolates causing human urinary tract infections.

  1993cited by this paper
• Fimbriation, capsulation, and iron-scavenging systems of Klebsiella strains associated with human urinary tract infection

  1992cited by this paper
• Adherence to respiratory epithelia by recombinant Escherichia coli expressing Klebsiella pneumoniae type 3 fimbrial gene products

  1992cited by this paper
• Lectinophagocytosis of type 1 fimbriated (mannose‐specific) Escherichia coli in the mouse peritoneum

  1992cited by this paper
• Fimbrial types among respiratory isolates belonging to the family Enterobacteriaceae

  1991cited by this paper
• Hemagglutinins of Klebsiella pneumoniae and K. oxytoca isolated from different sources.

  1991cited by this paper
• Roles of fimB and fimE in site-specific DNA inversion associated with phase variation of type 1 fimbriae in Escherichia coli

  1991cited by this paper
• Type V collagen as the target for type‐3 fimbriae, enterobacterial adherence organelles

  1990cited by this paper
• Identification and characterization of the genes encoding the type 3 and type 1 fimbrial adhesins of Klebsiella pneumoniae

  1989cited by this paper
• Expression of type 1 fimbriae and mannose-sensitive hemagglutinin by recombinant plasmids

  1989cited by this paper
• Type 1 pili are not necessary for colonization of the streptomycin-treated mouse large intestine by type 1-piliated Escherichia coli F-18 and E. coli K-12

  1989cited by this paper
• Bacterial lectins, cell‐cell recognition and infectious disease

  1987cited by this paper
• Characterization of genes encoding type 1 fimbriae of Klebsiella pneumoniae, Salmonella typhimurium, and Serratia marcescens

  1987cited by this paper
• Haemagglutinins and adherence properties to HeLa and intestine 407 cells of Klebsiella pneumoniae and Klebsiella oxytoca isolates.

  1987cited by this paper
• Correlation of the virulence of Klebsiella pneumoniae K1 and K2 with the presence of a plasmid encoding aerobactin

  1986cited by this paper
• The role of K antigens as virulence factors in Klebsiella.

  1986cited by this paper
• Regulation of production of type 1 pili among urinary tract isolates of Escherichia coli

  1986cited by this paper
• Two regulatory fim genes, fimB and fimE, control the phase variation of type 1 fimbriae in Escherichia coli.

  1986cited by this paper
• Construction and comparison of recombinant plasmids encoding type 1 fimbriae of members of the family Enterobacteriaceae

  1985cited by this paper
• An invertible element of DNA controls phase variation of type 1 fimbriae of Escherichia coli.

  1985cited by this paper
• Population shift in mannose-specific fimbriated phase of Klebsiella pneumoniae during experimental urinary tract infection in mice

  1985cited by this paper
• Construction and expression of recombinant plasmids encoding type 1 fimbriae of a urinary Klebsiella pneumoniae isolate

  1983cited by this paper
• Klebsiella pneumoniae-induced experimental pyelitis: the effect of piliation on infectivity.

  1982cited by this paper
• Effect of piliation on Klebsiella pneumoniae infection in rat bladders

  1980cited by this paper
• Epidemiology of Klebsiella and hospital-associated infections.

  1979cited by this paper
• Experimental pyelonephritis. XIV. Pyelonephritis in normal mice produced by inoculation of E. coli into the bladder lumen during water diuresis.

  1967cited by this paper
• Edinburgh Research Explorer Environmental regulation of the fim switch controlling type 1 fimbrial phase variation in Escherichia coli K-12: effects of temperature and media

  year unknowncited by this paper

• Differential contributions of ClpX and ClpP to pulmonary virulence in classical and hypervirulent Klebsiella pneumoniae

  2026cites this paper
• Study on Risk Factors of Death in Patients with Pneumonia Caused by Klebsiella pneumoniae Infection and Sepsis

  2026cites this paper
• Mannose-functionalized Nano-Therapeutics: A targeted strategy for combating bacterial infections

  2026cites this paper
• Klebsiella pneumoniae vaccines: Evolving the blueprint from traditional platforms to mucosal and nanoscale delivery.

  2026cites this paper
• A review on hypervirulent and multidrug-resistant Klebsiella pneumoniae: An emerging threat to human health.

  2026cites this paper
• Klebsiella pneumoniae Infections in Dogs: A One Health Review of Antimicrobial Resistance, Virulence Factors, Zoonotic Risk, and Emerging Alternatives

  2026cites this paper
• Comparative analysis of quorum sensing mechanisms in Pseudomonas aeruginosa and Klebsiella pneumoniae: implications for antibiotic resistance

  2025cites this paper
• Bacterial adhesion strategies and countermeasures in urinary tract infection

  2025cites this paper
• Modulation of virulence and metabolic profiles in Klebsiella pneumoniae under indole-mediated stress response

  2025cites this paper
• Protection Against Pneumonia Induced by Vaccination with Fimbriae Subunits from Klebsiella pneumoniae

  2025cites this paper
• Mobile genetic elements encoding antibiotic resistance genes and virulence genes in Klebsiella pneumoniae: important pathways for the acquisition of virulence and resistance

  2025cites this paper
• How Klebsiella pneumoniae controls its virulence

  2025influential citation
• Bioinformatics analysis of the in silico engineered protein vaccine with and without Escherichia coli heat labile enterotoxin adjuvant on the model of Klebsiella pneumoniae

  2025cites this paper
• Emergence of Recurrent Urinary Tract Infection: Dissecting the mechanism of Antimicrobial Resistance, Host-Pathogen Interaction, and Hormonal Imbalance.

  2025cites this paper
• A novel Klebsiella pneumoniae diguanylate cyclase contributes to intestinal cell adhesion, biofilm formation, iron utilization, and in vivo virulence by gastrointestinal infection

  2025cites this paper
• Heavy Metals and Carbapenem-Resistant Klebsiella pneumoniae in a River System of Odisha, India: Correlation and Integrated Risk Assessment

  2025influential citation
• Advances of Chinese herbal medicine and its active ingredients in the treatment of antibiotic-resistant Klebsiella pneumoniae infections: Therapeutic efficacy, mechanisms, and combination strategies

  2025cites this paper
• A Comprehensive Overview of Klebsiella Pneumoniae: Resistance Dynamics, Clinical Manifestations, and Therapeutic Options

  2025cites this paper
• Pathogenic analysis of Andinoacara rivulatus skin ulcer disease caused by Klebsiella pneumoniae in China

  2025cites this paper
• Succinate-driven virulence enhancement in hypervirulent Klebsiella pneumoniae via DcuSR two-component system

  2025cites this paper
• Polydextrose reduces the infection of Klebsiella pneumoniae in mice by downregulating the expression of TamA

  2025cites this paper
• Colonization, translocation, and evolution of opportunistic pathogens during hospital-associated infections

  2025cites this paper
• Genomic and phylogenetic analysis of hypervirulent Klebsiella pneumoniae ST23 in Ireland

  2025cites this paper
• Genomics, population dynamics, immune evasion and resistance determinants foster the competence and global dissemination of Klebsiella pneumoniae

  2025influential citation
• Understanding carbapenem-resistant hypervirulent Klebsiella pneumoniae: Key virulence factors and evolutionary convergence

  2024cites this paper
• Supplemental Sodium Nitroprusside and Spermidine Regulate Water Balance and Chlorophyll Pigments to Improve Sunflower Yield under Terminal Drought

  2024cites this paper
• Pathogenomics analysis of high-risk clone ST147 multidrug-resistant Klebsiella pneumoniae isolated from a patient in Egypt

  2024cites this paper
• First Report of Virulence Factors in Carbapenem-resistant Klebsiella pneumoniae from Maharashtra, India

  2024cites this paper
• Temperatures above 37°C increase virulence of a convergent Klebsiella pneumoniae sequence type 307 strain

  2024cites this paper
• Virulence Factors in Klebsiella pneumoniae: A Literature Review

  2024cites this paper
• Clinical and laboratory insights into the threat of hypervirulent Klebsiella pneumoniae.

  2024cites this paper
• Detection of virulent Klebsiella pneumoniae strains causing intestinal and extraintestinal infections during the 80s and 90s in Brazil

  2024cites this paper
• Plant-Origin Components: New Players to Combat Antibiotic Resistance in Klebsiella pneumoniae

  2024cites this paper
• Temperatures above 37°C increase virulence of a convergent Klebsiella pneumoniae sequence type 307 strain

  2024cites this paper
• General Overview of Klebsiella pneumonia: Epidemiology and the Role of Siderophores in Its Pathogenicity

  2024cites this paper
• Immunoprotective efficacy of 3 Klebsiella pneumoniae type I fimbriae proteins in a murine model.

  2024cites this paper
• Multidrug-resistant ESBL-producing Klebsiella pneumoniae complex in Czech hospitals, wastewaters and surface waters

  2024cites this paper
• Deciphering the gastrointestinal carriage of Klebsiella pneumoniae

  2024cites this paper
• KPC-2 and VIM-1 producing Klebsiella pneumoniae ST39 high-risk clone isolated from a clinical sample in Volos, Greece.

  2024cites this paper
• Inorganic Polyphosphate Affects Biofilm Assembly, Capsule Formation, and Virulence of Hypervirulent ST23 Klebsiella pneumoniae.

  2024cites this paper
• Effects of Polyphosphate metabolism Mutations on Biofilm, Capsule Formation and Virulence Traits in Hypervirulent ST23 Klebsiella pneumoniae SGH10

  2023cites this paper
• Regulation of biofilm formation in Klebsiella pneumoniae

  2023cites this paper
• Extensive Expression of the Virulome Related to Antibiotic Genotyping in Nosocomial Strains of Klebsiella pneumoniae

  2023cites this paper
• Widespread Detection of Yersiniabactin Gene Cluster and Its Encoding Integrative Conjugative Elements (ICEKp) among Nonoutbreak OXA-48-Producing Klebsiella pneumoniae Clinical Isolates from Spain and the Netherlands

  2023cites this paper
• Antimicrobial resistance and molecular characterization of Klebsiella species causing bovine mastitis in Nghe An province, Vietnam

  2023cites this paper
• The evolutionary mechanism of non-carbapenemase carbapenem-resistant phenotypes in Klebsiella spp

  2023cites this paper
• Virulence factors in carbapenem-resistant hypervirulent Klebsiella pneumoniae

  2023cites this paper
• Comparative genomics and virulome analysis reveal unique features associated with clinical strains of Klebsiella pneumoniae and Klebsiella quasipneumoniae from Trinidad, West Indies

  2023influential citation
• Highly conserved composite transposon harbouring aerobactin iuc3 in Klebsiella pneumoniae from pigs

  2023cites this paper
• Latent evolution of biofilm formation depends on life-history and genetic background

  2023cites this paper
• Molecular basis of Klebsiella pneumoniae colonization in host.

  2023cites this paper
• Urine-mediated suppression of Klebsiella pneumoniae mucoidy is counteracted by spontaneous Wzc variants altering capsule chain length

  2023cites this paper
• Urinary Tract Infections Caused by K. pneumoniae in Kidney Transplant Recipients – Epidemiology, Virulence and Antibiotic Resistance

  2022cites this paper
• Conserved FimK Truncation Coincides with Increased Expression of Type 3 Fimbriae and Cultured Bladder Epithelial Cell Association in Klebsiella quasipneumoniae

  2022cites this paper
• Hypervirulence and Multiresistance to Antibiotics in Klebsiella pneumoniae Strains Isolated from Patients with Hospital- and Community-Acquired Infections in a Mexican Medical Center

  2022influential citation
• Whole genome sequencing of Klebsiella pneumoniae clinical isolates sequence type 627 isolated from Egyptian patients

  2022cites this paper
• Mechanisms regulating the airborne survival of Klebsiella pneumoniae under different relative humidity and temperature levels.

  2022cites this paper
• Treatment history shapes the evolution of complex carbapenem-resistant phenotypes in Klebsiella spp.

  2022cites this paper
• Autophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectives

  2022cites this paper
• Submarine Outfalls of Treated Wastewater Effluents are Sources of Extensively- and Multidrug-Resistant KPC- and OXA-48-Producing Enterobacteriaceae in Coastal Marine Environment

  2022cites this paper
• Multidrug-Resistant Klebsiella variicola Isolated in the Urine of Healthy Bovine Heifers, a Potential Risk as an Emerging Human Pathogen

  2022cites this paper
• Genomic insights of beta-lactamase producing Klebsiella quasipneumoniae subsp. similipneumoniae belonging to sequence type 1699 from retail market fish, India

  2022cites this paper
• CONVERGENCE OF MULTIPLE RESISTANCE AND HYPERVIRULENCE IN KLEBSIELLA PNEUMONIAE

  2022cites this paper
• Review of Known and Unknown Facts of Klebsiella Pneumoniae and its Relationship with Antibiotics

  2022cites this paper
• Regulation of ECP fimbriae‐related genes by the transcriptional regulator RcsAB in Klebsiella pneumoniae NTUH‐K2044

  2022influential citation
• Clinically relevant pathogens on surfaces display differences in survival and transcriptomic response in relation to probiotic and traditional cleaning strategies

  2022cites this paper
• Virulence factors of uropathogens and their role in host pathogen interactions

  2022cites this paper
• Additive effect of the probiotics Lactobacillus exopolysaccharides and the Satureja calamintha extracts on enteropathogenic Escherichia coli adhesion

  2022cites this paper
• Novel Virulence Factors Deciphering Klebsiella pneumoniae KpC4 Infect Maize as a Crossing-Kingdom Pathogen: An Emerging Environmental Threat

  2022cites this paper
• Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis

  2022cites this paper
• Characteristics of community-acquired carbapenem-resistant Enterobacterales.

  2022cites this paper
• Potential therapeutic targets of Klebsiella pneumoniae: a multi-omics review perspective.

  2021cites this paper
• Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14

  2021cites this paper
• From K. pneumoniae Colonization to Dissemination: An Overview of Studies Implementing Murine Models

  2021cites this paper
• From Klebsiella pneumoniae Colonization to Dissemination: An Overview of Studies Implementing Murine Models

  2021cites this paper
• SdiA, a Quorum-Sensing Regulator, Suppresses Fimbriae Expression, Biofilm Formation, and Quorum-Sensing Signaling Molecules Production in Klebsiella pneumoniae

  2021cites this paper
• Evaluation of Biofilm Formation in Klebsiella Pneumoniae and Antibiotic Resistance

  2021cites this paper
• Molecular prevalence of resistance determinants, virulence factors and capsular serotypes among colistin resistance carbapenemase producing Klebsiella pneumoniae: a multi-centric retrospective study

  2021cites this paper
• Development of an Immunochromatographic Strip Using Conjugated Gold Nanoparticles for the Rapid Detection of Klebsiella pneumoniae Causing Neonatal Sepsis

  2021cites this paper
• Determination of Klebsiella pneumoniae Susceptibility to Antibiotics Using Infrared Microscopy.

  2021cites this paper
• Accessory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX

  2021cites this paper
• Phase variable expression of pdcB, a phosphodiesterase influences sporulation in Clostridioides difficile

  2021cites this paper
• Foodborne ESKAPE Biofilms and Antimicrobial Resistance: lessons Learned from Clinical Isolates

  2021cites this paper
• Prophylaxis and Treatment against Klebsiella pneumoniae: Current Insights on This Emerging Anti-Microbial Resistant Global Threat

  2021cites this paper
• Genetic and Molecular Mechanisms of Multidrug-Resistance in Uropathogens and Novel Therapeutic Combat

  2021cites this paper
• Innate Host Defense against Klebsiella pneumoniae and the Outlook for Development of Immunotherapies

  2021cites this paper
• Exploring the action of new FimH inhibitors against CTX– 15 enzyme by enzoinformatics approach: A plausible arsenal against drug-resistant uropathogenic bacterial strains

  2021cites this paper
• Virulence profiles of Klebsiella pneumoniae isolated from 2 large dairy farms in China.

  2021cites this paper
• Comparative genomics with a multidrug-resistant Klebsiella pneumoniae isolate reveals the panorama of unexplored diversity in Northeast Brazil.

  2020cites this paper
• Kpi, a chaperone-usher pili system associated with the worldwide-disseminated high-risk clone Klebsiella pneumoniae ST-15

  2020cites this paper
• Klebsiella pneumoniae: Prevalence, Reservoirs, Antimicrobial Resistance, Pathogenicity, and Infection: A Hitherto Unrecognized Zoonotic Bacterium

  2020cites this paper
• Animal Model To Study Klebsiella pneumoniae Gastrointestinal Colonization and Host-to-Host Transmission

  2020influential citation
• Amoxicillin exposure significantly increases the population and virulence of antibiotic-resistant Klebsiella pathogen in the simulated human intestinal microbiota

  2020cites this paper
• Amoxicillin exposure significantly increases the population and virulence of antibiotic-resistant Klebsiella pathogen in the simulated human intestinal microbiota

  2020cites this paper
• Shotgun proteomic analysis of ESBL-producing and non-ESBL-producing Klebsiella Pneumoniae clinical isolates.

  2020cites this paper
• An Overview of Virulence, Antimicrobial Resistance, Biofilm Formation and Antibiofilm Strategies of Klebsiella Species

  2020cites this paper
• Klebsiella pneumoniae: microbiological characterization, antimicrobial resistance, and virulence

  2020cites this paper
• Functional Insights From KpfR, a New Transcriptional Regulator of Fimbrial Expression That Is Crucial for Klebsiella pneumoniae Pathogenicity

  2020influential citation
• Environmental dissemination of mcr-1 positive Enterobacteriaceae by Chrysomya spp. (common blowfly): An increasing public health risk.

  2019cites this paper
• Prevalence of Potential Virulence Genes in Klebsiella spp. Isolated from Cows with Clinical Mastitis on Large Chinese Dairy Farms

  2019cites this paper