Perinatal asphyxia induced neuronal loss by apoptosis in the neonatal rat striatum: a combined TUNEL and stereological study.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Experimental Neurology

• Publication date

  2002-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1006/EXNR.2001.7855PMID 11869031
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Developmental cell death: morphological diversity and multiple mechanisms

  2004cited by this paper
• Neurotoxicity of N-methyI-D-aspartate is markedly enhanced in developing rat central nervous system

  2002cited by this paper
• Delayed Neurodegeneration in Neonatal Rat Thalamus after Hypoxia–Ischemia Is Apoptosis

  2001cited by this paper
• Perinatal asphyxia results in changes in presynaptic bouton number in striatum and cerebral cortex-a stereological and behavioral analysis.

  2000cited by this paper
• Involvement of Caspase-3 in Cell Death after Hypoxia–Ischemia Declines during Brain Maturation

  2000cited by this paper
• Towards the use of state-of-the-art stereology in experimental gerontology.

  2000cited by this paper
• Neuronal death in newborn striatum after hypoxia-ischemia is necrosis and evolves with oxidative stress.

  2000cited by this paper
• Apoptosis Has a Prolonged Role in the Neurodegeneration after Hypoxic Ischemia in the Newborn Rat

  2000cited by this paper
• Analysis of cell death in the trochlear nucleus of the chick embryo: Calibration of the optical disector counting method reveals systematic bias

  1999cited by this paper
• The apoptosis cascade — morphological and immunohistochemical methods for its visualization

  1999cited by this paper
• Pathophysiology of perinatal brain damage.

  1999cited by this paper
• Is the Cell Death Pathway Triggered by the Mitochondrion or the Endoplasmic Reticulum?

  1999cited by this paper
• Prenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control study.

  1999cited by this paper
• Cellular mechanisms of hypoxic injury in the developing brain.

  1999cited by this paper
• Histological changes and neurotransmitter levels three months following perinatal asphyxia in the rat.

  1999cited by this paper
• Electron Microscopic Evidence against Apoptosis as the Mechanism of Neuronal Death in Global Ischemia

  1999cited by this paper
• Oxidative Metabolism, Apoptosis and Perinatal Brain Injury

  1999cited by this paper
• Neuron loss in the mouse hippocampus following prenatal injection of tritiated thymidine or saline

  1999cited by this paper
• Nerve cell loss in the thalamic mediodorsal nucleus in Huntington’s disease

  1999cited by this paper
• Apoptosis in a neonatal rat model of cerebral hypoxia-ischemia.

  1998cited by this paper
• Hypothermia during or after severe perinatal asphyxia prevents increase in cyclic GMP-related nitric oxide levels in the newborn rat striatum.

  1998cited by this paper
• Temporal evolution of neuronal changes in cerebral hypoxia-ischemia in developing rats: a quantitative light microscopic study.

  1998cited by this paper
• Variation of fractionator estimates and its prediction

  1998cited by this paper
• A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

  1998cited by this paper
• correction: A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

  1998cited by this paper
• The coefficient of error of optical fractionator population size estimates: a computer simulation comparing three estimators

  1998cited by this paper
• Postnatal development of the rat striatum--a study using in situ DNA end labeling technique.

  1998cited by this paper
• Caesarean section birth with general anesthesia increases dopamine‐mediated behavior in the adult rat

  1998cited by this paper
• Temporal evolution of neuronal changes in cerebral hypoxia– ischemia in developing rats: a quantitative light microscopic study

  1998cited by this paper
• Programmed cell death is a universal feature of embryonic and postnatal neuroproliferative regions throughout the central nervous system

  1998cited by this paper
• Mechanisms of cerebral injury in perinatal asphyxia and strategies for prevention.

  1998cited by this paper
• Deafferentation Causes Apoptosis in Cortical Sensory Neurons in the Adult Rat

  1997cited by this paper
• The shape of cell death.

  1997cited by this paper
• Excitotoxic neuronal death in the immature brain is an apoptosis‐necrosis morphological continuum

  1997cited by this paper
• Quantification without pontification: Choosing a method for counting objects in sectioned tissues

  1997cited by this paper
• Delayed neuronal death following perinatal asphyxia in rat

  1997cited by this paper
• Non‐NMDA and NMDA receptor‐mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: Further evidence for an apoptosis‐necrosis continuum

  1997cited by this paper
• Short- and long-term effects of perinatal asphyxia on monoamine, amino acid and glycolysis product levels measured in the basal ganglia of the rat.

  1997cited by this paper
• Long term changes in NADPH-diaphorase reactivity in striatal and cortical neurons following experimental perinatal asphyxia: neuroprotective effects of hypothermia.

  1997cited by this paper
• Mechanisms of secondary brain injury.

  1996cited by this paper
• Calcium-related damage in ischemia.

  1996cited by this paper
• Development of GABA and calcium binding proteins immunoreactivity in the rat hippocampus following neonatal anoxia.

  1996cited by this paper
• Hypoxia and brain development.

  1996cited by this paper
• Calcium signaling in neurons: molecular mechanisms and cellular consequences.

  1995cited by this paper
• Multiple Hypothesis Testing

  1995cited by this paper
• Nicotine treatment counteracts perinatal asphyxia-induced changes in the mesostriatal/limbic dopamine systems and in motor behaviour in the four-week-old male rat.

  1995cited by this paper
• Apoptosis, oncosis, and necrosis. An overview of cell death.

  1995cited by this paper
• Ischemic delayed neuronal death. A mitochondrial hypothesis.

  1995cited by this paper
• Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: evidence for apoptosis during selective neuronal loss.

  1995cited by this paper
• A cautionary note on the use of the TUNEL stain to determine apoptosis

  1995cited by this paper
• Apoptosis in substantia nigra following developmental hypoxic-ischemic injury.

  1995cited by this paper
• Repeated asphyxia causes loss of striatal projection neurons in the fetal sheep brain.

  1995cited by this paper
• Long-term effects of perinatal asphyxia on basal ganglia neurotransmitter systems studied with microdialysis in rat.

  1994cited by this paper
• Neurocircuitry of the basal ganglia studied by monitoring neurotransmitter release

  1994cited by this paper
• Toward an understanding of the molecular mechanisms of physiological cell death.

  1993cited by this paper
• Programmed cell death and the control of cell survival: lessons from the nervous system.

  1993cited by this paper
• Social controls on cell survival and cell death

  1992cited by this paper
• Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

  1992cited by this paper
• Definition and incidence of apoptosis : A historical perspective

  1991cited by this paper
• Cell death during development of the nervous system.

  1991cited by this paper
• Apoptosis: The Molecular Basis of Cell Death

  1991cited by this paper
• Experimental Biology of Cerebral Hypoxia-Ischemia: Relation to Perinatal Brain Damage

  1990cited by this paper
• Physiological and pathophysiological roles of excitatory amino acids during central nervous system development.

  1990cited by this paper
• Quantitative morphological analysis of striatal cholinergic neurons in perinatal asphyxia

  1990cited by this paper
• Calcium, neuronal hyperexcitability and ischemic injury.

  1989cited by this paper
• Neurotoxicity of N-methyl-D-aspartate is markedly enhanced in developing rat central nervous system.

  1988cited by this paper
• Stereology of arbitrary particles *

  1986cited by this paper
• The pathophysiology of brain ischemia

  1983cited by this paper
• Neurotransmitter alterations in a model of perinatal hypoxic‐ischemic brain injury

  1983cited by this paper
• Cell death: the significance of apoptosis.

  1980cited by this paper
• Neurological Aspects of Perinatal Asphyxia

  1974cited by this paper
• Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics

  1972cited by this paper

• Uneven Distribution of Purkinje Cell Injury in the Cerebellar Vermis of Term Neonates with Hypoxic-Ischemic Encephalopathy

  2024cites this paper
• HIF-1 α may play a role in late pregnancy hypoxia-induced autism-like behaviors in offspring rats.

  2021cites this paper
• Effects of Prenatal Hypoxia on Nervous System Development and Related Diseases

  2021cites this paper
• Animal models for neonatal brain injury induced by hypoxic ischemic conditions in rodents.

  2020cites this paper
• Acrobatic exercise recovers object recognition memory impairment in hypoxic‐ischemic rats

  2020cites this paper
• Uneven distribution of Purkinje cell injury in the cerebellar vermis of term neonates with hypoxic-ischemic encephalopathy

  2020cites this paper
• Deep hypothermia prevents striatal alterations produced by perinatal asphyxia: Implications for the prevention of dyskinesia and psychosis

  2020cites this paper
• Thioredoxin 1 plays a protective role in retinas exposed to perinatal hypoxia-ischemia.

  2019cites this paper
• Oscillating-gradient diffusion magnetic resonance imaging detects acute subcellular structural changes in the mouse forebrain after neonatal hypoxia-ischemia

  2019cites this paper
• An electrochemiluminescent method for glutamate measurement in small microdialysate samples in asphyxiated young rats.

  2018cites this paper
• Impaired Organization of GABAergic Neurons Following Prenatal Hypoxia.

  2018cites this paper
• Mild prenatal hypoxia-ischemia leads to social deficits and central and peripheral inflammation in exposed offspring.

  2018cites this paper
• Acylethanolamides and endocannabinoid signaling system in dorsal striatum of rats exposed to perinatal asphyxia.

  2017cites this paper
• Increased risk of developing schizophrenia in animals exposed to cigarette smoke during the gestational period

  2017cites this paper
• Nitric Oxide Production in the Striatum and Cerebellum of a Rat Model of Preterm Global Perinatal Asphyxia

  2017cites this paper
• Vulnerability to a Metabolic Challenge Following Perinatal Asphyxia Evaluated by Organotypic Cultures: Neonatal Nicotinamide Treatment

  2017cites this paper
• Genetic and perinatal risk factors for movement disorders

  2017cites this paper
• 25 years of research on global asphyxia in the immature rat brain

  2017cites this paper
• Neonatal anoxia leads to time dependent progression of mitochondrial linked apoptosis in rat cortex and associated long term sensorimotor deficits

  2016cites this paper
• Argon as a potential strategy against the neurotoxicity of nitrous oxide and perinatal hypoxia/ischemia induced brain injury

  2016cites this paper
• Cryostat Slice Irregularities May Introduce Bias in Tissue Thickness Estimation: Relevance for Cell Counting Methods

  2015influential citation
• Fetal asphyctic preconditioning protects against perinatal asphyxia- induced apoptosis and astrogliosis in neonatal brain.

  2015cites this paper
• Melatonin and Its Therapeutic Implications in Injuries of the Developing Brain and Retina

  2014cites this paper
• Efeito da exposição crônica à fumaça de cigarro, durante o período pré-natal, na predisposição ao desenvolvimento da esquizofrenia em ratos: análise comportamental e neuroquímica

  2013cites this paper
• Environmental Enrichment Decreases Asphyxia-Induced Neurobehavioral Developmental Delay in Neonatal Rats

  2013cites this paper
• Inflammatory response and oxidative stress in developing rat brain and its consequences on motor behavior following maternal administration of LPS and perinatal anoxia

  2013cites this paper
• Early changes in the synapses of the neostriatum induced by perinatal asphyxia

  2012cites this paper
• Prenatal exposure to cigarette smoke causes persistent changes in the oxidative balance and in DNA structural integrity in rats submitted to the animal model of schizophrenia.

  2011cites this paper
• Effects of fetal exposure to lipopolysaccharide, perinatal anoxia and sensorimotor restriction on motor skills and musculoskeletal tissue: implications for an animal model of cerebral palsy.

  2011cites this paper
• Changes in neostriatal and hippocampal synaptic densities in perinatal asphyctic male and female young rats: Role of hypothermia.

  2011cites this paper
• Magnesium sulfate treatment alters fetal cerebellar gene expression responses to hypoxia

  2010cites this paper
• Brain apoptosis and carotid artery reactivity in fetal asphyctic preconditioning.

  2010influential citation
• Fetal asphyxia leads to the loss of striatal presynaptic boutons in adult rats

  2010cites this paper
• Epidemiology-driven neurodevelopmental animal models of schizophrenia.

  2010cites this paper
• Fetal asphyctic preconditioning protects against perinatal asphyxia-induced behavioral consequences in adulthood.

  2010cites this paper
• L-carnitine pre-treatment reduces apoptotic cell death in seven-day-old rats hypoxia ischemia

  2010cites this paper
• Protein ubiquitination in postsynaptic densities after hypoxia in rat neostriatum is blocked by hypothermia.

  2009cites this paper
• Neuroprotective effects of methylprednisolone and hypothermia after experimental spinal cord injury: a histopathological and stereological study.

  2009cites this paper
• Effects of perinatal asphyxia on the neurobehavioral and retinal development of newborn rats.

  2009cites this paper
• Altered expression of cyclooxygenase-2, presenilins and oxygen radical scavenging enzymes in a rat model of global perinatal asphyxia.

  2008cites this paper
• Fetal asphyxia induces a preconditioning effect in the cerebral prefrontal cortex

  2008cites this paper
• Acute brain cytokine responses after global birth hypoxia in the rat

  2008influential citation
• Influence of hypoxia and ischemia preconditioning on bilirubin damage to astrocytes.

  2007cites this paper
• The Neuropathology of Autism

  2007cites this paper
• Birth insults involving hypoxia produce long-term increases in hippocampal [125I]insulin-like growth factor-I and -II receptor binding in the rat.

  2006cites this paper
• The effect of prenatal hypoxia on brain development: short- and long-term consequences demonstrated in rodent models.

  2006cites this paper
• Der Einfluss des Geschlechts auf die Neuronenanzahl in einem APP/PS1- doppeltransgenen Mausmodell der Alzheimer-Krankheit

  2006cites this paper
• C-section birth per se or followed by acute global asphyxia altered emotional behaviour in neonate and adult rats.

  2006cites this paper
• Effect of neonatal body temperature on postanoxic, potentially neurotoxic iron accumulation in the rat brain.

  2006cites this paper
• Mild Hypothermia and the Distribution of Cerebral Lesions in Neonates With Hypoxic-Ischemic Encephalopathy

  2005cites this paper
• Hypoxic-Ischemic Encephalopathy Mild Hypothermia and the Distribution of Cerebral Lesions in Neonates With

  2005cites this paper
• Hipotermia en la encefalopatía hipóxico-isquémica neonatal: hipotermia leve y distribución de las lesiones cerebrales en neonatos

  2005cites this paper
• Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease.

  2004cites this paper
• Histological changes of the dopaminergic nigrostriatal system in aging

  2004cites this paper
• VEGFR-1: A Safe Target for Prophylaxis of Retinopathy of Prematurity?

  2004cites this paper
• Increased Brain Levels of F2-Isoprostane Are an Early Marker of Behavioral Sequels in a Rat Model of Global Perinatal Asphyxia

  2004cites this paper
• Animal Model Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease

  2004cites this paper
• A delayed increase in hippocampal proliferation following global asphyxia in the neonatal rat.

  2003cites this paper
• Impact of perinatal asphyxia on the GABAergic and locomotor system.

  2003cites this paper
• Blockade of D1 dopaminergic transmission alleviates c-fos induction and cleaved caspase-3 expression in the brains of rat pups exposed to prenatal cocaine or perinatal asphyxia.

  2003cites this paper