DNA microarray analysis of gene expression in alveolar epithelial cells in response to TNFα, LPS, and cyclic stretch

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Physiological Genomics

• Publication date

  2004-11-17

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1152/PHYSIOLGENOMICS.00153.2004
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Phosphoinositide 3-OH kinase inhibition prevents ventilation-induced lung cell activation.

  2004cited by this paper
• Pulmonary Edema Fluid from Patients with Early Lung Injury Stimulates Fibroblast Proliferation through IL-1β-Induced IL-6 Expression 1

  2004influential reference
• Role of IRF‐1 and caspase‐7 in IFN‐γ enhancement of Fas‐mediated apoptosis in ACHN renal cell carcinoma cells

  2003cited by this paper
• Modulation of Human β-Defensin-2 Transcription in Pulmonary Epithelial Cells by Lipopolysaccharide-Stimulated Mononuclear Phagocytes Via Proinflammatory Cytokine Production1

  2003cited by this paper
• A Prominent Role for Airway Epithelial NF-κB Activation in Lipopolysaccharide-Induced Airway Inflammation1

  2003cited by this paper
• Many chemokines including CCL20/MIP‐3α display antimicrobial activity

  2003cited by this paper
• Statistical tests for identifying differentially expressed genes in time-course microarray experiments

  2003cited by this paper
• Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

  2002cited by this paper
• Signaling for survival and apoptosis in the immune system

  2002influential reference
• NF-?B regulation in the immune system

  2002cited by this paper
• Differences in LPS‐Induced Activation of Bronchial Epithelial Cells (BEAS‐2B) and Type II‐Like Pneumocytes (A‐549)

  2002cited by this paper
• Ephrin stimulation modulates T cell chemotaxis

  2002cited by this paper
• Dexamethasone and tumor necrosis factor-alpha act together to induce the cellular inhibitor of apoptosis-2 gene and prevent apoptosis in a variety of cell types.

  2002cited by this paper
• Quantitative noise analysis for gene expression microarray experiments

  2002cited by this paper
• Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-&agr; and interleukin-6 messenger RNA*

  2002cited by this paper
• Interferon regulatory factor-1 mediates interferon-gamma-induced apoptosis in ovarian carcinoma cells.

  2002cited by this paper
• Alveolar Epithelium in Host Defence: Cytokine Production

  2002cited by this paper
• Interferon regulatory factor‐1 mediates interferon‐γ‐induced apoptosis in ovarian carcinoma cells

  2002cited by this paper
• NF-κB regulation in the immune system

  2002cited by this paper
• Role of IRF-1 and caspase-7 in IFN-gamma enhancement of Fas-mediated apoptosis in ACHN renal cell carcinoma cells.

  2001cited by this paper
• Role of LPS-induced microfilament depolymerization in MIP-2 production from rat pneumocytes.

  2001cited by this paper
• Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients

  2001cited by this paper
• Validation of a new live cell strain system: characterization of plasma membrane stress failure.

  2001cited by this paper
• The biology of chemokines and their receptors.

  2000influential reference
• Molecular mechanisms of lipopolysaccharide induced ICAM-1 expression in A549 cells

  2000cited by this paper
• Mechanical stretch stimulates macrophage inflammatory protein-2 secretion from fetal rat lung cells.

  2000cited by this paper
• Effects of Mechanical Ventilation on Release of Cytokines into Systemic Circulation in Patients with Normal Pulmonary Function

  2000cited by this paper
• Production of tumour necrosis factor alpha by primary cultured rat alveolar epithelial cells.

  2000cited by this paper
• Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9.

  1999cited by this paper
• LPS-induced depolymerization of cytoskeleton and its role in TNF-α production by rat pneumocytes.

  1999influential reference
• Death deflected: IL‐15 inhibits TNF‐α‐mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL‐15Rα chain

  1999cited by this paper
• Stretch induces cytokine release by alveolar epithelial cells in vitro.

  1999cited by this paper
• The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN

  1999cited by this paper
• Expression of three members of the TNF-R family of receptors (4-1BB, lymphotoxin-beta receptor, and Fas) in human lung.

  1998cited by this paper
• Alveolar type II-like cells release G-CSF as neutrophil chemotactic activity.

  1998cited by this paper
• DNA chips: State-of-the art

  1998cited by this paper
• Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activities

  1998cited by this paper
• Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors.

  1998cited by this paper
• Adenovirus E1A upregulates interleukin-8 expression induced by endotoxin in pulmonary epithelial cells.

  1997cited by this paper
• Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model.

  1997cited by this paper
• A Cytosolic Granzyme B Inhibitor Related to the Viral Apoptotic Regulator Cytokine Response Modifier A Is Present in Cytotoxic Lymphocytes*

  1996cited by this paper
• Mechanical Strain Induces pp60 Activation and Translocation to Cytoskeleton in Fetal Rat Lung Cells (*)

  1996cited by this paper
• Participation of pulmonary alveolar epithelial cells in lung inflammation.

  1995cited by this paper
• The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.

  1995cited by this paper
• Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.

  1995cited by this paper
• The NF‐kappa B precursor p105 and the proto‐oncogene product Bcl‐3 are I kappa B molecules and control nuclear translocation of NF‐kappa B.

  1993cited by this paper
• Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung.

  1990cited by this paper
• highlighted topics Cellular Responses to Mechanical Stress Invited Review: Mechanisms of ventilator-induced lung injury: a perspective

  year unknowncited by this paper

• Transcription factor CEBPA suppresses sepsis induced lung injury by activating SIRT4 transcription

  2025cites this paper
• Prediction of lung overdistension during mechanical ventilation using micro-RNA and gene expression

  2025cites this paper
• Protective effect of recombinant interleukin-10 on newborn rat lungs exposed to short-term sublethal hyperoxia

  2024cites this paper
• Zinc-Dependent Histone Deacetylases in Lung Endothelial Pathobiology

  2024cites this paper
• Circular RNA MKLN1 promotes epithelial-mesenchymal transition in pulmonary fibrosis by regulating the miR-26a/b-5p/CDK8 axis in human alveolar epithelial cells and mice models

  2024cites this paper
• Aerosol exposure at air-liquid-interface (AE-ALI) in vitro toxicity system characterisation: Particle deposition and the importance of air control responses.

  2024cites this paper
• Mechanotransduction in the Vocal Fold Microenvironment: A Narrative Review.

  2024cites this paper
• Mechanical Stretch Promotes Invasion of Lung Cancer Cells via Activation of Tumor Necrosis Factor-alpha

  2023cites this paper
• NF-κB-dependent repression of Sox18 transcription factor requires the epigenetic regulators histone deacetylases 1 and 2 in acute lung injury

  2022cites this paper
• Lung Epithelial Regulation of BCL2 Related Protein A1 (BCL2A1) by Coronaviruses (SARS-CoV) and Type I Interferon Signaling

  2021cites this paper
• Mesenchymal stromal (stem) cell therapy modulates miR-193b-5p expression to attenuate sepsis-induced acute lung injury

  2021cites this paper
• Quantitative Phosphoproteomics Reveals Cell Alignment and Mitochondrial Length Change under Cyclic Stretching in Lung Cells

  2020influential citation
• The Long Pentraxin 3 (PTX3) Suppresses Immunity to Cutaneous Leishmaniasis by Regulating CD4+ T Helper Cell Response.

  2020cites this paper
• Pretreatment with adalimumab reduces ventilator-induced lung injury in an experimental model

  2020cites this paper
• Evolution of Bioengineered Lung Models: Recent Advances and Challenges in Tissue Mimicry for Studying the Role of Mechanical Forces in Cell Biology

  2019cites this paper
• The role of airway epithelial cell and natural killer cell interactions during RSV infection

  2019cites this paper
• The Safety and Efficiency of Addressing ARDS Using Stem Cell Therapies in Clinical Trials

  2019cites this paper
• Mechanical strain mimicking breathing amplifies alterations in gene expression induced by SiO2 NPs in lung epithelial cells

  2019influential citation
• The Long Pentraxin 3 (PTX3) Suppresses Immunity to Cutaneous Leishmaniasis by Negatively Regulating Th17 Response

  2019cites this paper
• Ex vivo perfusion induces a time‐ and perfusate‐dependent molecular repair response in explanted porcine lungs

  2018cites this paper
• SOCS-1 ameliorates smoke inhalation-induced acute lung injury through inhibition of ASK-1 activity and DISC formation.

  2017cites this paper
• Cellular force assay detects altered contractility caused by a nephritis‐associated mutation in nonmuscle myosin IIA

  2017cites this paper
• Charakterisierung des langen Pentraxins PTX3 beim Huhn

  2017cites this paper
• Biotrauma and Ventilator-Induced Lung Injury: Clinical Implications.

  2016cites this paper
• The effect of diet-induced serum hypercholesterolemia on the surfactant system and the development of lung injury

  2016cites this paper
• Investigation of the Role of Tensile Forces in Cellular Response to Chemotherapeutic Agents

  2016cites this paper
• Neue Erkenntnisse zur Pathogenese des akuten Atemnotsyndroms

  2016cites this paper
• Lipopolysaccharide challenge induces long pentraxin 3 expression in mice independently from acute lung injury.

  2015cites this paper
• Advances in Understanding of the Pathogenesis of Acute Respiratory Distress Syndrome

  2015cites this paper
• Bench-to-bedside review : Biotrauma and modulation of the innate immune response

  2015cites this paper
• Extracellular Forces Cause the Nucleus to Deform in a Highly Controlled Anisotropic Manner

  2015cites this paper
• Lung Transcriptomics during Protective Ventilatory Support in Sepsis-Induced Acute Lung Injury

  2015cites this paper
• TRIM family proteins: emerging class of RING E3 ligases as regulator of NF‐κB pathway

  2015cites this paper
• The Long Pentraxin PTX3 as a Key Component of Humoral Innate Immunity and a Candidate Diagnostic for Inflammatory Diseases

  2014cites this paper
• Analysis of gene expression changes in A549 cells induced by organic compounds from respirable air particles.

  2014cites this paper
• TMEM16A protein attenuates lipopolysaccharide-mediated inflammatory response of human lung epithelial cell line A549

  2014cites this paper
• Advances in ventilator-associated lung injury: prevention is the target

  2014cites this paper
• Hyperosmolarity Invokes Distinct Anti-Inflammatory Mechanisms in Pulmonary Epithelial Cells: Evidence from Signaling and Transcription Layers

  2014cites this paper
• Open lung approach with low tidal volume mechanical ventilation attenuates lung injury in rats with massive brain damage

  2014cites this paper
• Microarray-Based Gene Expression Profiling Suggests adaptation of Lung Epithelial Cells Subjected to Chronic Cyclic Strain

  2014cites this paper
• Chemokines induced in human respiratory epithelial cells by IL-1 family of cytokines.

  2014cites this paper
• Impact of a Lung-Protective Ventilatory Strategy on Systemic and Pulmonary Inflammatory Responses During Laparoscopic Surgery: Is It Really Helpful?

  2014cites this paper
• β-carotene regulates expression of β-carotene 15,15'-monoxygenase in human alveolar epithelial cells.

  2013cites this paper
• The role of TLR 4 in the pathogenesis of indirect acute lung injury

  2013cites this paper
• MEK/ERK pathway mediates PKC activation‐induced recruitment of PKCζ and MMP‐9 to podosomes

  2013cites this paper
• Regulation of interleukin-6 secretion by the two-pore-domain potassium channel Trek-1 in alveolar epithelial cells.

  2013cites this paper
• LPS induces pp60c‐srcmediated tyrosine phosphorylation of hsp90 in lung vascular endothelial cells and mouse lung

  2013cites this paper
• PKC Activation Induces Inflammatory Response and Cell Death in Human Bronchial Epithelial Cells

  2013cites this paper
• Pentraxin 3 accelerates lung injury in high tidal volume ventilation in mice.

  2012cites this paper
• Ventilator-induced lung injury: role of protein-protein interaction in mechanosensation.

  2012cites this paper
• Effects of respiratory mechanical forces on the pharmacological response of lung cancer cells to chemotherapeutic agents

  2012cites this paper
• Eph-A2 promotes permeability and inflammatory responses to bleomycin-induced lung injury.

  2012cites this paper
• Ventilator-Induced Lung Injury: Mechanisms and Future Therapeutic Interventions

  2012cites this paper
• Mechanical stress induces lung fibrosis by epithelial–mesenchymal transition*

  2012cites this paper
• Deciphering cellular responses to pathogens using genomics data

  2012cites this paper
• Microarray Meta-Analysis Identifies Acute Lung Injury Biomarkers in Donor Lungs That Predict Development of Primary Graft Failure in Recipients

  2012cites this paper
• Effects of vitamin D on inflammation and oxidative stress in airway epithelial cells

  2012cites this paper
• Claudin 1 Mediates TNFα-Induced Gene Expression and Cell Migration in Human Lung Carcinoma Cells

  2012cites this paper
• C URRENT OPINION Pathophysiology of ventilator-associated lung injury

  2012cites this paper
• The Lung in Multiorgan Failure

  2012cites this paper
• Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

  2012cites this paper
• Stretching Mechanotransduction from the Lung to the Lab: Approaches and Physiological Relevance in Drug Discovery

  2012cites this paper
• Src tyrosine kinase inhibition prevents pulmonary ischemia–reperfusion-induced acute lung injury

  2012cites this paper
• Pathophysiology of ventilator-associated lung injury

  2012cites this paper
• Mechanobiology in lung epithelial cells: measurements, perturbations, and responses.

  2012cites this paper
• Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis.

  2012cites this paper
• Ventilation-induced lung injury.

  2011cites this paper
• Pathogen Recognition by the Long Pentraxin PTX3

  2011cites this paper
• Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice.

  2011cites this paper
• The Role of Purinergic Signaling on Deformation Induced Injury and Repair Responses of Alveolar Epithelial Cells

  2011cites this paper
• A single small dose of ketamine prevents lung injury following hepatic ischemia‐reperfusion in rabbits

  2011cites this paper
• Significant elevation of plasma pentraxin 3 in patients with pelvic inflammatory disease

  2011cites this paper
• Neuroimmune regulation of ventilator-induced lung injury.

  2011cites this paper
• The Protein Kinase C Cascade Regulates Recruitment of Matrix Metalloprotease 9 to Podosomes and Its Release and Activation

  2010cites this paper
• Pentraxins in innate immunity: lessons from PTX3

  2010cites this paper
• The long way of biomarkers: from bench to bedside

  2010cites this paper
• Regulatory T cell-mediated resolution of lung injury: identification of potential target genes via expression profiling.

  2010cites this paper
• Effects of the TLR2 Agonists MALP-2 and Pam3Cys in Isolated Mouse Lungs

  2010cites this paper
• Activating transcription factor 3 confers protection against ventilator-induced lung injury.

  2010cites this paper
• PTX3 as a potential biomarker of acute lung injury: supporting evidence from animal experimentation

  2010cites this paper
• Growth factors and cytokines in acute lung injury.

  2010cites this paper
• Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability.

  2010cites this paper
• Influence of chemical and mechanical stress on precision-cut lung slices

  2010cites this paper
• Recent advances and new opportunities in lung mechanobiology.

  2010cites this paper
• Pattern recognition by pentraxins.

  2009cites this paper
• Molecular Mechanism of Podosome Formation and Proteolytic Function in Human Bronchial Epithelial Cells

  2009cites this paper
• Inflammatory Response and Barrier Properties of a New Alveolar Type 1-Like Cell Line (TT1)

  2009cites this paper
• Phorbol ester‐induced podosomes in normal human bronchial epithelial cells

  2009influential citation
• Active uptake of dendritic cell-derived exovesicles by epithelial cells induces the release of inflammatory mediators through a TNF-alpha-mediated pathway.

  2009cites this paper
• Phagocytes Are a Source of the Fluid-Phase Pattern Recognition Receptor PTX3: Interplay between Cellular and Humoral Innate Immunity

  2009cites this paper
• Pattern Recognition Receptor–Dependent Mechanisms of Acute Lung Injury

  2009cites this paper
• Pentraxins: Multifunctional proteins at the interface of innate immunity and inflammation

  2009cites this paper
• Cyclic Stretch Magnitude and Duration Affect Rat Alveolar Epithelial Gene Expression

  2009cites this paper
• Common skate (Raja kenojei) secretes pentraxin into the cutaneous secretion: The first skin mucus lectin in cartilaginous fish.

  2009cites this paper
• RECOMBINANT HUMAN SOLUBLE TUMOR NECROSIS FACTOR-ALPHA RECEPTOR FUSION PROTEIN PARTLY ATTENUATES VENTILATOR-INDUCED LUNG INJURY

  2009cites this paper
• Characterization of pentraxin 3 in the horse and its expression in airways

  2009cites this paper
• Anesthetic-induced Improvement of the Inflammatory Response to One-lung Ventilation

  2009cites this paper
• ICAM-1 AS A NOVEL BINDING PARTNER FOR LPS TO MEDIATE TLR4-INDEPENDENT CELL ACTIVATION by

  2008cites this paper
• Mechanical Stress Upregulates Intercellular Adhesion Molecule-1 in Pulmonary Epithelial Cells

  2008cites this paper
• Differential gene profiling in acute lung injury identifies injury-specific gene expression*

  2008cites this paper