MAPK activation in nociceptive neurons and pain hypersensitivity.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Life Science

• Publication date

  2004-04-09

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.LFS.2004.01.007PMID 15041446
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats

  2003influential reference
• Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors.

  2003cited by this paper
• Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain.

  2003cited by this paper
• Identification of MEK1 as a novel target for the treatment of neuropathic pain

  2003cited by this paper
• NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals.

  2003cited by this paper
• p38 Mitogen-Activated Protein Kinase Is Activated after a Spinal Nerve Ligation in Spinal Cord Microglia and Dorsal Root Ganglion Neurons and Contributes to the Generation of Neuropathic Pain

  2003influential reference
• Tumor Necrosis Factor-α Induces Mechanical Allodynia after Spinal Nerve Ligation by Activation of p38 MAPK in Primary Sensory Neurons

  2003cited by this paper
• Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neurons.

  2003cited by this paper
• P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

  2003cited by this paper
• Phosphorylation of CREB and Mechanical Hyperalgesia Is Reversed by Blockade of the cAMP Pathway in a Time-Dependent Manner after Repeated Intramuscular Acid Injections

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  2003cited by this paper
• Role of the sensory neuron cytoskeleton in second messenger signaling for inflammatory pain.

  2003cited by this paper
• Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE2 release and thermal hyperalgesia

  2003cited by this paper
• Phosphorylation of extracellular signal-regulated kinases 1/2 is predominantly enhanced in the microglia of the rat spinal cord following dorsal root transection.

  2003cited by this paper
• Activation of p38 mitogen‐activated protein kinase in spinal microglia is a critical link in inflammation‐induced spinal pain processing

  2003cited by this paper
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• Differential Activation of Extracellular Signal-Regulated Protein Kinase in Primary Afferent Neurons Regulates Brain-Derived Neurotrophic Factor Expression after Peripheral Inflammation and Nerve Injury

  2003influential reference
• Molecular mechanisms of cancer pain

  2002cited by this paper
• Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn.

  2002cited by this paper
• Increases in the phosphorylation of cyclic AMP response element binding protein (CREB) and decreases in the content of calcineurin accompany thermal hyperalgesia following chronic constriction injury in rats

  2002cited by this paper
• Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal‐regulated kinase (ERK) and c‐Jun N‐terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus

  2002cited by this paper
• Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injury

  2002cited by this paper
• ERK MAP Kinase Activation in Superficial Spinal Cord Neurons Induces Prodynorphin and NK-1 Upregulation and Contributes to Persistent Inflammatory Pain Hypersensitivity

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• p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia.

  2002influential reference
• Contribution of the spared primary afferent neurons to the pathomechanisms of neuropathic pain

  2002cited by this paper
• Activation of spinal extracellular signaling-regulated kinase-1 and -2 by intraplantar carrageenan in rodents.

  2002cited by this paper
• BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn.

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• Expression of neurotrophic factors in the dorsal root ganglion in a rat model of lumbar disc herniation

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• Phosphorylation of Extracellular Signal-Regulated Kinase in Primary Afferent Neurons by Noxious Stimuli and Its Involvement in Peripheral Sensitization

  2002influential reference
• Can we conquer pain?

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• Macrophage and lymphocyte invasion of dorsal root ganglia after peripheral nerve lesions in the rat.

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• In the Cellular Garden of Forking Paths: How p38 MAPKs Signal for Downstream Assistance

  2002cited by this paper
• Trk receptors: mediators of neurotrophin action.

  2001cited by this paper
• Neurotrophins use the Erk5 pathway to mediate a retrograde survival response

  2001cited by this paper
• Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain.

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• Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Activation in Somatodendritic Compartments: Roles of Action Potentials, Frequency, and Mode of Calcium Entry

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• Dorsal horn lesion resulting from spinal root avulsion leads to the accumulation of stress-responsive proteins.

  2001cited by this paper
• Neurotrophins use the Erk5 pathway to mediate a retrograde survival response

  2001influential reference
• Spinal cord glia: new players in pain.

  2001cited by this paper
• Metabotropic Glutamate Receptor Subtypes 1 and 5 Are Activators of Extracellular Signal-Regulated Kinase Signaling Required for Inflammatory Pain in Mice

  2001cited by this paper
• Increased phosphorylation of cyclic AMP response element‐binding protein (CREB) in the superficial dorsal horn neurons following partial sciatic nerve ligation

  2001cited by this paper
• The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory

  2001cited by this paper
• On Trk for retrograde signaling.

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• Molecular mechanisms of nociception

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• Nociceptor Sensitization by Extracellular Signal-Regulated Kinases

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• Nerve growth factor modulates the activation status and fast axonal transport of ERK 1/2 in adult nociceptive neurones.

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• The role of neuroinflammation and neuroimmune activation in persistent pain

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• Glial activation: a driving force for pathological pain.

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• Nerve injury proximal or distal to the DRG induces similar spinal glial activation and selective cytokine expression but differential behavioral responses to pharmacologic treatment

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• Mammalian MAP kinase signalling cascades

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• Regulation of voltage‐dependent calcium channels in rat sensory neurones involves a Ras‐mitogen‐activated protein kinase pathway

  2000cited by this paper
• Carrageenan-induced thermal hyperalgesia in the mouse: role of nerve growth factor and the mitogen-activated protein kinase pathway.

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• Neuronal plasticity: increasing the gain in pain.

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• Activity of p44/42 MAP kinase in the caudal subnucleus of trigeminal spinal nucleus is increased following perioral noxious stimulation in the mouse.

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• CREB couples neurotrophin signals to survival messages.

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• Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3–CA1 synapses

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• Acute peripheral inflammation induces moderate glial activation and spinal IL-1beta expression that correlates with pain behavior in the rat.

  1999cited by this paper
• Trks: Signal transduction and intracellular pathways

  1999cited by this paper
• Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity.

  1999cited by this paper
• Upregulation of brain-derived neurotrophic factor and neuropeptide Y in the dorsal ascending sensory pathway following sciatic nerve injury in rat.

  1999cited by this paper
• Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human.

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• Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity.

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• Circadian Regulation of cAMP Response Element-mediated Gene Expression in the Suprachiasmatic Nuclei*

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• New insights into the control of MAP kinase pathways.

  1999cited by this paper
• Neuronal activity-dependent cell survival mediated by transcription factor MEF2.

  1999cited by this paper
• Microglial reactions after subcutaneous formalin injection into the rat hind paw.

  1999cited by this paper
• Acute peripheral inflammation induces moderate glial activation and spinal IL-1β expression that correlates with pain behavior in the rat

  1999cited by this paper
• Injured primary sensory neurons switch phenotype for brain-derived neurotrophic factor in the rat.

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  1999cited by this paper
• Building blocks of pain: the regulation of key molecules in spinal sensory neurones during development and following peripheral axotomy.

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• Transcriptional and posttranslational plasticity and the generation of inflammatory pain.

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• Effects of ion channel activity on development of dorsal root ganglion neurons.

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• Transcription factor regulation of prodynorphin gene expression following rat hindpaw inflammation.

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