Biological function through network topology: a survey of the human diseasome

Abstract Molecular network data are increasingly becoming available, necessitating the development of well performing computational tools for their analyses. Such tools enabled conceptually different approaches for exploring human diseases to be undertaken, in particular, those that study the relationship between a multitude of biomolecules within a cell. Hence, a new field of network biology has emerged as part of systems biology, aiming to untangle the complexity of cellular network organization. We survey current network analysis methods that aim to give insight into human disease.

• Publication year

  2012

• Venue

  Briefings in Functional Genomics

• Publication date

  2012-09-07

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1093/bfgp/els037PMID 22962330PMCID 7109924
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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