Electrospray mass spectrometry and fragmentation of N-linked carbohydrates derivatized at the reducing terminus

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of the American Society for Mass Spectrometry

• Publication date

  2000-10-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S1044-0305(00)00156-2PMID 11014452
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Linkage position determination in lithium-cationized disaccharides: tandem mass spectrometry and semiempirical calculations

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• Linkage position determination in oligosaccharides: mass spectrometry (MS/MS) study of lithium-cationized carbohydrates

  1990cited by this paper
• Structural analysis of oligosaccharides by tandem mass spectrometry: Collisional activation of sodium adduct ions

  1990cited by this paper
• Desorption mass spectrometry of oligosaccharides coupled with hydrophobic chromophores.

  1990influential reference
• Oligosaccharide characterization with high-energy collision-induced dissociation mass spectrometry.

  1990cited by this paper
• Reexamination of the pyridylamination used for fluorescence labeling of oligosaccharides and its application to glycoproteins.

  1984cited by this paper
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  1983cited by this paper
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  1982cited by this paper

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