The 3BP2 Adapter Protein Is Required for Chemoattractant-Mediated Neutrophil Activation

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Immunology

• Publication date

  2012-07-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.1103184PMID 22815290
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• 3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions.

  2011cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
• Signaling requirements for translocation of P‐Rex1, a key Rac2 exchange factor involved in chemoattractant‐stimulated human neutrophil function

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• The Src Family Kinases Hck and Fgr Are Dispensable for Inside-Out, Chemoattractant-Induced Signaling Regulating β2 Integrin Affinity and Valency in Neutrophils, but Are Required for β2 Integrin-Mediated Outside-In Signaling Involved in Sustained Adhesion1

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• The Rac Effector p67phox Regulates Phagocyte NADPH Oxidase by Stimulating Vav1 Guanine Nucleotide Exchange Activity

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  2000cited by this paper
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• Flipping the Switch: Minireview The Structural Basis for Signaling through the CRIB Motif

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  2000cited by this paper
• The Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 1/2 Pathway Is Involved in formyl-Methionyl-Leucyl-Phenylalanine-Induced p47phox Phosphorylation in Human Neutrophils1

  2000cited by this paper
• p21-activated Kinase (PAK1) Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Kinase-1 (PDK1)*

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  1999cited by this paper
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  1999influential reference
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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998influential reference
• G Proteins and Small GTPases: Distant Relatives Keep in Touch

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• A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1

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  1997cited by this paper
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  1997cited by this paper
• Common and distinct intracellular signaling pathways in human neutrophils utilized by platelet activating factor and FMLP.

  1997cited by this paper
• Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

  1997cited by this paper
• Activation of p38 in stimulated human neutrophils: phosphorylation of the oxidase component p47phox by p38 and ERK but not by JNK.

  1996cited by this paper
• The Rac Target NADPH Oxidase p67 Interacts Preferentially with Rac2 Rather Than Rac1 (*)

  1996cited by this paper
• Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions

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• Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

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• The Renaturable 69- and 63-kDa Protein Kinases That Undergo Rapid Activation in Chemoattractant-stimulated Guinea Pig Neutrophils Are p21-Activated Kinases*

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• G Protein-coupled Chemoattractant Receptors Regulate Lyn Tyrosine Kinase·Shc Adapter Protein Signaling Complexes (*)

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• Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1 (*)

  1995cited by this paper
• Cdc42 and PAK-mediated Signaling Leads to Jun Kinase and p38 Mitogen-activated Protein Kinase Activation (*)

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