The caudate: a key node in the neuronal network imbalance of insomnia?

D. Stoffers,E. Altena,Y. D. van der Werf,E. Sanz-Arigita,Thom Voorn,R. Astill,R. Strijers,D. Waterman,E. V. van Someren

Published 2013 in Brain : a journal of neurology

ABSTRACT

Although insomnia is common and disabling, its neural correlates remain enigmatic. Stoffers et al. use structural and functional MRI to demonstrate that hyperarousal, its clearest characteristic, involves reduced recruitment and connectivity of the left caudate that may predispose to insomnia and perpetuate it.

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