Computerized Assessment of Social Approach Behavior in Mouse

Altered sociability is a core feature of a variety of human neurological disorders, including autism. Social behaviors may be tested in animal models, such as mice, to study the biological basis of sociability and how this is altered in neurodevelopmental disorders. A quantifiable social behavior frequently used to assess sociability in the mouse is the tendency to approach and interact with an unfamiliar mouse. Here we present a novel computer-assisted method for scoring social approach behavior in mice using a three-chambered apparatus and freely available software. We find consistent results between data scored using the computer-assisted method and a human observer, making computerized assessment a reliable, low cost, high-throughput method for testing sociability.

• Publication year

  2009

• Venue

  Frontiers in Behavioral Neuroscience

• Publication date

  2009-08-24

• Fields of study

  Biology, Medicine, Computer Science, Psychology

• Identifiers
  DOI 10.3389/neuro.08.048.2009PMID 20198104PMCID 2802322
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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