Cytoskeleton modulates coupling between availability and activation of cardiac sodium channel.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  American Journal of Physiology

• Publication date

  1997-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/ajpheart.1997.273.4.H1832PMID 9362250
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• A mutation in the pore of the sodium channel alters gating.

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  1995cited by this paper
• Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation.

  1994cited by this paper
• Structure and function of voltage-gated ion channels.

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• Genotype-phenotype correlations in human skeletal muscle sodium channel diseases.

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  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
• Spectrin-based membrane skeleton: a multipotential adaptor between plasma membrane and cytoplasm.

  1990cited by this paper
• Structural parts involved in activation and inactivation of the sodium channel

  1989cited by this paper
• Single sodium channels from canine ventricular myocytes: voltage dependence and relative rates of activation and inactivation.

  1989influential reference
• Ankyrin and spectrin associate with voltage-dependent sodium channels in brain

  1988cited by this paper
• Cytoskeletal damage during myocardial ischemia: changes in vinculin immunofluorescence staining during total in vitro ischemia in canine heart.

  1987cited by this paper
• Microtubules and desmin filaments during onset of heart hypertrophy in rat: a double immunoelectron microscope study.

  1987cited by this paper
• Effects of microtubule-disrupting agents on insulin binding and degradation in isolated cardiocytes from adult rat.

  1983cited by this paper
• Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

  1981cited by this paper
• Identification of a large molecular weight peptide associated with a tetrodotoxin binding protein from the electroplax of Electrophorus electricus.

  1980cited by this paper
• The steady state TTX-sensitive (“window”) sodium current in cardiac Purkinje fibres

  1979cited by this paper
• Inactivation of the sodium channel. I. Sodium current experiments

  1977cited by this paper

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  2012cites this paper
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  2011cites this paper
• The genetics of conduction disease.

  2010cites this paper
• Tubulin polymerization modifies cardiac sodium channel expression and gating.

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• Non-anti-mitotic concentrations of taxol reduce breast cancer cell invasiveness.

  2009cites this paper
• Protein-protein interactions involving voltage-gated sodium channels: Post-translational regulation, intracellular trafficking and functional expression.

  2009cites this paper
• Model of ionic currents through microtubule nanopores and the lumen.

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  2008cites this paper
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  2007influential citation
• Microtubules in cardiac toxicity and disease

  2007cites this paper
• The Role of Mechanosensitive Fibroblasts in the Heart

  2005cites this paper
• Sodium channels as macromolecular complexes: implications for inherited arrhythmia syndromes.

  2005cites this paper
• Molecular physiology of cardiac repolarization.

  2005cites this paper
• Mechanisms of inherited cardiac conduction disease.

  2005cites this paper
• A Nonsense Mutation of the Sodium Channel Gene SCN2A in a Patient with Intractable Epilepsy and Mental Decline

  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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• Voltage-gated Na+ channels: multiplicity of expression, plasticity, functional implications and pathophysiological aspects

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