The mitochondrial machinery for import of precursor proteins.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Methods in molecular biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/978-1-59745-466-7_7PMID 17951683
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chaperoning through the mitochondrial intermembrane space.

  2006cited by this paper
• Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller.

  2006cited by this paper
• A disulfide relay system in the intermembrane space of mitochondria that mediates protein import.

  2005cited by this paper
• Protein import into mitochondria.

  2005cited by this paper
• Chopped, trapped or tacked--protein translocation into the IMS of mitochondria.

  2005cited by this paper
• A railroad switch in mitochondrial protein import.

  2005cited by this paper
• The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins.

  2005cited by this paper
• How does the TOM complex mediate insertion of precursor proteins into the mitochondrial outer membrane?

  2005cited by this paper
• Erv1 mediates the Mia40-dependent protein import pathway and provides a functional link to the respiratory chain by shuttling electrons to cytochrome c.

  2005cited by this paper
• Mitochondria take center stage in aging and neurodegeneration

  2005cited by this paper
• Pam17 Is Required for Architecture and Translocation Activity of the Mitochondrial Protein Import Motor

  2005cited by this paper
• The Import Motor of the Yeast Mitochondrial TIM23 Preprotein Translocase Contains Two Different J Proteins, Tim14 and Mdj2*

  2005cited by this paper
• Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions

  2005cited by this paper
• Apoptotic pathways: ten minutes to dead.

  2005cited by this paper
• Sequential triage of transmembrane segments by Sec61α during biogenesis of a native multispanning membrane protein

  2005cited by this paper
• Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17.

  2005cited by this paper
• Biogenesis of the Protein Import Channel Tom40 of the Mitochondrial Outer Membrane

  2004cited by this paper
• Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins

  2004cited by this paper
• Two novel proteins in the mitochondrial outer membrane mediate β-barrel protein assembly

  2004cited by this paper
• The Tim8-Tim13 Complex of Neurospora crassa Functions in the Assembly of Proteins into Both Mitochondrial Membranes*

  2004cited by this paper
• Sam35 of the Mitochondrial Protein Sorting and Assembly Machinery Is a Peripheral Outer Membrane Protein Essential for Cell Viability*

  2004cited by this paper
• The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria

  2004cited by this paper
• Assembling the mitochondrial outer membrane

  2004cited by this paper
• The protein import and assembly machinery of the mitochondrial outer membrane.

  2004cited by this paper
• Tob38, a novel essential component in the biogenesis of β‐barrel proteins of mitochondria

  2004cited by this paper
• The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane.

  2004cited by this paper
• Mitochondrial import and the twin-pore translocase

  2004cited by this paper
• Identification of Tim40 That Mediates Protein Sorting to the Mitochondrial Intermembrane Space*

  2004cited by this paper
• The Presequence Translocase-associated Protein Import Motor of Mitochondria

  2004cited by this paper
• The Role of Hot13p and Redox Chemistry in the Mitochondrial TIM22 Import Pathway*

  2004cited by this paper
• New developments in mitochondrial assembly.

  2004cited by this paper
• The Protein Import Machinery of Mitochondria*

  2004cited by this paper
• Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70.

  2003cited by this paper
• A J-protein is an essential subunit of the presequence translocase–associated protein import motor of mitochondria

  2003cited by this paper
• An Essential Role of Sam50 in the Protein Sorting and Assembly Machinery of the Mitochondrial Outer Membrane*

  2003cited by this paper
• Machinery for protein sorting and assembly in the mitochondrial outer membrane

  2003cited by this paper
• J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix

  2003cited by this paper
• Role of a Highly Conserved Bacterial Protein in Outer Membrane Protein Assembly

  2003cited by this paper
• Evolutionary conservation of biogenesis of β-barrel membrane proteins

  2003cited by this paper
• Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM–TIM–preprotein supercomplex

  2003cited by this paper
• Functional cooperation and separation of translocators in protein import into mitochondria, the double-membrane bounded organelles

  2003cited by this paper
• Evolutionary conservation of biogenesis of beta-barrel membrane proteins.

  2003cited by this paper
• Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria

  2003cited by this paper
• Tom40, the import channel of the mitochondrial outer membrane, plays an active role in sorting imported proteins

  2003cited by this paper
• A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1.

  2002cited by this paper
• The Tim9p–Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier

  2002cited by this paper
• Mitochondrial Import of the ADP/ATP Carrier: the Essential TIM Complex of the Intermembrane Space Is Required for Precursor Release from the TOM Complex

  2002cited by this paper
• Delivery of nascent polypeptides to the mitochondrial surface.

  2002cited by this paper
• Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel.

  2002cited by this paper
• The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel.

  2002cited by this paper
• Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes.

  2002cited by this paper
• Molecular chaperones as essential mediators of mitochondrial biogenesis.

  2002cited by this paper
• Protein translocase of the outer mitochondrial membrane: role of import receptors in the structural organization of the TOM complex.

  2002cited by this paper
• Genome‐wide analysis of mRNAs targeted to yeast mitochondria

  2002cited by this paper
• Protein import into and across the mitochondrial inner membrane: role of the TIM23 and TIM22 translocons.

  2002cited by this paper
• A presequence- and voltage-sensitive channel of the mitochondrial preprotein translocase formed by Tim23

  2001cited by this paper
• Biogenesis of Porin of the Outer Mitochondrial Membrane Involves an Import Pathway via Receptors and the General Import Pore of the Tom Complex

  2001cited by this paper
• Mitochondrial Import Driving Forces: Enhanced Trapping by Matrix Hsp70 Stimulates Translocation and Reduces the Membrane Potential Dependence of Loosely Folded Preproteins

  2001cited by this paper
• Multistep assembly of the protein import channel of the mitochondrial outer membrane

  2001cited by this paper
• The Mitochondrial Protein Import Motor

  2000cited by this paper
• Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20.

  2000cited by this paper
• Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane.

  2000cited by this paper
• The role of the TIM8–13 complex in the import of Tim23 into mitochondria

  2000cited by this paper
• Membrane potential-driven protein import into mitochondria. The sorting sequence of cytochrome b(2) modulates the deltapsi-dependence of translocation of the matrix-targeting sequence.

  2000cited by this paper
• Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase

  1999cited by this paper
• Distribution of Binding Sequences for the Mitochondrial Import Receptors Tom20, Tom22, and Tom70 in a Presequence-carrying Preprotein and a Non-cleavable Preprotein*

  1999cited by this paper
• The dimensions of the protein import channels in the outer and inner mitochondrial membranes.

  1999cited by this paper
• Targeting of tail‐anchored proteins to yeast mitochondria in vivo

  1999cited by this paper
• The translocon: a dynamic gateway at the ER membrane.

  1999cited by this paper
• Tim9, a new component of the TIM22·54 translocase in mitochondria

  1999cited by this paper
• The preprotein translocation channel of the outer membrane of mitochondria.

  1998cited by this paper
• Preprotein Translocase of the Outer Mitochondrial Membrane: Molecular Dissection and Assembly of the General Import Pore Complex

  1998cited by this paper
• Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins

  1998cited by this paper
• Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5

  1998cited by this paper
• Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins

  1998cited by this paper
• The Sorting Route of Cytochrome b 2Branches from the General Mitochondrial Import Pathway at the Preprotein Translocase of the Inner Membrane*

  1997cited by this paper
• The Tim54p–Tim22p Complex Mediates Insertion of Proteins into the Mitochondrial Inner Membrane

  1997cited by this paper
• Protein import into mitochondria.

  1997cited by this paper
• SOM 1, a small new gene required for mitochondrial inner membrane peptidase function inSaccharomyces cerevisiae

  1996cited by this paper
• Tom71, a Novel Homologue of the Mitochondrial Preprotein Receptor Tom70*

  1996cited by this paper
• Identification of a third yeast mitochondrial Tom protein with tetratrico peptide repeats

  1996cited by this paper
• The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria.

  1996cited by this paper
• Acidic receptor domains on both sides of the outer membrane mediate translocation of precursor proteins into yeast mitochondria.

  1995cited by this paper
• The mitochondrial receptor complex: Mom22 is essential for cell viability and directly interacts with preproteins

  1995cited by this paper
• The sorting signal of cytochrome b2 promotes early divergence from the general mitochondrial import pathway and restricts the unfoldase activity of matrix Hsp70.

  1995cited by this paper
• Mitochondrial Hsp70/MIM44 complex facilitates protein import

  1994cited by this paper
• The mitochondrial outer membrane protein Mas22p is essential for protein import and viability of yeast.

  1994cited by this paper
• Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane.

  1994cited by this paper
• Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44

  1994cited by this paper
• MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae.

  1994cited by this paper
• Biogenesis of the mitochondrial receptor complex. Two receptors are required for binding of MOM38 to the outer membrane surface.

  1993cited by this paper
• A mitochondrial protease with two catalytic subunits of nonoverlapping specificities.

  1993cited by this paper
• Inner membrane protease I, an enzyme mediating intramitochondrial protein sorting in yeast.

  1991cited by this paper
• A yeast mitochondrial outer membrane protein essential for protein import and cell viability

  1990cited by this paper
• A mitochondrial import receptor for the ADP/ATP carrier.

  1990cited by this paper
• Protein import into yeast mitochondria is accelerated by the outer membrane protein MAS70.

  1990cited by this paper
• Domain structure of mitochondrial and chloroplast targeting peptides.

  1989cited by this paper
• MOM19, an import receptor for mitochondrial precursor proteins.

  1989cited by this paper
• Transport of proteins to the mitochondrial intermembrane space: the ‘sorting’ domain of the cytochrome c1 presequence is a stop‐transfer sequence specific for the mitochondrial inner membrane.

  1987cited by this paper
• Distinct steps in the import of ADP/ATP carrier into mitochondria.

  1987cited by this paper

• Mitochondrial protein translocation machinery: From TOM structural biogenesis to functional regulation

  2022cites this paper
• MRPL13 is a Prognostic Cancer Biomarker and Correlates with Immune Infiltrates in Breast Cancer

  2020cites this paper
• OTT_A_263998 12255..12268

  2020cites this paper
• Clueless is a conserved ribonucleoprotein that binds the ribosome at the mitochondrial outer membrane

  2016cites this paper
• Molecular responses of Saccharomyces cerevisiae to near-zero growth rates

  2016cites this paper
• Proteome adaptation of Saccharomyces cerevisiae to severe calorie restriction in Retentostat cultures.

  2014cites this paper
• Structural and functional studies of mitochondrial small Tim proteins

  2013cites this paper
• Legionella pneumophila Secretes a Mitochondrial Carrier Protein during Infection

  2012cites this paper
• Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis

  2012cites this paper
• Analysis of the regulatory and catalytic domains of PTEN‐induced kinase‐1 (PINK1)

  2012cites this paper
• Hijacking Mitochondria: Bacterial Toxins that Modulate Mitochondrial Function

  2012cites this paper
• Plasticity of TOM complex assembly in skeletal muscle mitochondria in response to chronic contractile activity.

  2012cites this paper
• The Core Components of Organelle Biogenesis and Membrane Transport in the Hydrogenosomes of Trichomonas vaginalis

  2011cites this paper
• Targeting of Neisserial PorB to the mitochondrial outer membrane: an insight on the evolution of β‐barrel protein assembly machines

  2011cites this paper
• The Essentials of Protein Import in the Degenerate Mitochondrion of Entamoeba histolytica

  2010cites this paper
• Both the p33 and p55 subunits of the Helicobacter pylori VacA toxin are targeted to mammalian mitochondria.

  2010cites this paper
• Predicting proteomes of mitochondria and related organelles from genomic and expressed sequence tag data.

  2009cites this paper
• Jid1 is a J‐protein functioning in the mitochondrial matrix, unable to directly participate in endoplasmic reticulum associated protein degradation

  2009cites this paper
• MOLECULAR MECHANISMS OF MAMMALIAN MITOCHONDRIAL DNA REPLICATION AND TRANSCRIPTION

  2009cites this paper
• Compartmentalization of metabolic pathways in Candida albicans : a matter of transport

  2009cites this paper
• The three domains of the mitochondrial outer membrane protein Mim1 have discrete functions in assembly of the TOM complex

  2009cites this paper
• Biochemical aspects of the neuroprotective mechanism of PTEN‐induced kinase‐1 (PINK1)

  2008cites this paper
• The mitochondrial view of Blastocladiella emersonii.

  2008cites this paper