Genetic engineering of a zeaxanthin-rich potato by antisense inactivation and co-suppression of carotenoid epoxidation.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Metabolic Engineering

• Publication date

  2002-10-01

• Fields of study

  Agricultural and Food Sciences, Medicine, Biology

• Identifiers
  DOI 10.1006/MBEN.2002.0234PMID 12646321
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Radioimmunoassay for the determination of free and conjugated abscisic acid

  2004cited by this paper
• Complex regulation of ABA biosynthesis in plants.

  2002cited by this paper
• Plant Metabolic Engineering—Entering the S Curve

  2002cited by this paper
• Metabolic engineering of xanthophyll content in tomato fruits

  2002cited by this paper
• 1-Deoxy-d-xylulose-5-phosphate Synthase, a Limiting Enzyme for Plastidic Isoprenoid Biosynthesis in Plants*

  2001cited by this paper
• Genetic manipulation of carotenoid biosynthesis: strategies, problems and achievements.

  2001cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Carotenoid biosynthesis and biotechnological application.

  2001cited by this paper
• Carotenoids in the retina and lens: possible acute and chronic effects on human visual performance.

  2001cited by this paper
• Lutein, zeaxanthin, and the macular pigment.

  2001cited by this paper
• Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm.

  2000cited by this paper
• In vitro and in situ inhibition of carotenoid biosynthesis in Capsicum annuum by bleaching herbicides.

  2000cited by this paper
• Elevation of the provitamin A content of transgenic tomato plants

  2000cited by this paper
• Metabolic engineering of beta-carotene and lycopene content in tomato fruit.

  2000cited by this paper
• Application of high‐performance liquid chromatography with photodiode array detection to the metabolic profiling of plant isoprenoids

  2000cited by this paper
• Metabolic engineering of plant carotenoids.

  2000cited by this paper
• The potential for the improvement of carotenoid levels in foods and the likely systemic effects

  2000cited by this paper
• High-light-dependent upregulation of carotenoids and their antioxidative properties in the cyanobacterium Synechocystis PCC 6803

  1999cited by this paper
• Seed-specific overexpression of phytoene synthase: increase in carotenoids and other metabolic effects

  1999cited by this paper
• Engineered isoprenoid pathway enhances astaxanthin production in Escherichia coli.

  1999cited by this paper
• Metabolic engineering of the terpenoid biosynthetic pathway of Escherichia coli for production of the carotenoids β-carotene and zeaxanthin

  1999cited by this paper
• Identification of lutein and zeaxanthin oxidation products in human and monkey retinas.

  1997cited by this paper
• Dynamic properties of the minor chlorophyll a/b binding proteins of photosystem II, an in vitro model for photoprotective energy dissipation in the photosynthetic membrane of green plants.

  1996cited by this paper
• Molecular identification of zeaxanthin epoxidase of Nicotiana plumbaginifolia, a gene involved in abscisic acid biosynthesis and corresponding to the ABA locus of Arabidopsis thaliana.

  1996cited by this paper
• Purification in an active state and properties of the 3-step phytoene desaturase from Rhodobacter capsulatus overexpressed in Escherichia coli.

  1996cited by this paper
• Understanding and controlling transgene expression

  1995cited by this paper
• Constitutive expression of a fruit phytoene synthase gene in transgenic tomatoes causes dwarfism by redirecting metabolites from the gibberellin pathway

  1995cited by this paper
• The biological properties of carotenoids

  1994cited by this paper
• Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration

  1994cited by this paper
• Comparative Study of the Effect of Paprika Processing on the Carotenoids in Peppers (Capsicum annuum) of the Bola and Agridulce Varieties

  1994cited by this paper
• Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group.

  1994cited by this paper
• The Effects of Illumination on the Xanthophyll Composition of the Photosystem II Light-Harvesting Complexes of Spinach Thylakoid Membranes

  1994cited by this paper
• Identification and genetic analysis of normal and mutant phytoene synthase genes of tomato by sequencing, complementation and co-suppression

  1993cited by this paper
• A single polypeptide catalyzing the conversion of phytoene to zeta-carotene is transcriptionally regulated during tomato fruit ripening.

  1992cited by this paper
• Potato granule-bound starch synthase promoter-controlled GUS expression: regulation of expression after transient and stable transformation

  1992cited by this paper
• Evaluation of reversed-phase liquid chromatographic columns for recovery and selectivity of selected carotenoids.

  1992cited by this paper
• Carotene-oxygen radical interactions.

  1992cited by this paper
• Biochemical characterization of transgenic tomato plants in which carotenoid synthesis has been inhibited through the expression of antisense RNA to pTOM5

  1992cited by this paper
• Identification of a cDNA for the plastid-located geranylgeranyl pyrophosphate synthase from Capsicum annuum: correlative increase in enzyme activity and transcript level during fruit ripening.

  1992cited by this paper
• Resolution of lutein and zeaxanthin using a non-endcapped, lightly carbon-loaded C18 high-performance liquid chromatographic column

  1991cited by this paper
• Carotenoid composition of yellow pepper during ripening: isolation of beta-cryptoxanthin 5,6-epoxide

  1991cited by this paper
• Carotenoid desaturases from Rhodobacter capsulatus and Neurospora crassa are structurally and functionally conserved and contain domains homologous to flavoprotein disulfide oxidoreductases.

  1990cited by this paper
• Both developmental and metabolic signals activate the promoter of a class I patatin gene

  1989cited by this paper
• Binary Agrobacterium vectors for plant transformation.

  1984cited by this paper
• The nature and biosynthesis of the carotenoids of different colour varieties of Capsicum annuum.

  1970cited by this paper
• Kohlen wasserstoffe in der umgebung des menschen : I. Mitt. Eine methode zur simultanen bestimmung von dreizehn polycyclischen kohlenwasserstoffen

  1965cited by this paper
• A revised medium for rapid growth and bio assays with tobacco tissue cultures

  1962cited by this paper

• Genetic and biochemical analyses identify a major locus, GH-PA1, underlying pollen carotenoid accumulation and pigmentation in upland cotton

  2025cites this paper
• Carotenoids in Potato Tubers: A Bright Yellow Future Ahead

  2025influential citation
• Genome Editing Technologies to Improve Health‐Related Phytocompounds in Crops

  2025cites this paper
• Genetic and Agronomic Approaches to Micronutrient Biofortification in Solanaceae Plants

  2025cites this paper
• Comparative study on the mechanism of yellow petal formation in Paphiopedilum armeniacum: an integrated transcriptomic and metabolomic analysis of three Paphiopedilum species

  2025cites this paper
• Vegetables: potential role for nutritional security

  2024cites this paper
• De novo domestication: what about the weeds?

  2024cites this paper
• Potato Biofortification: A Systematic Literature Review on Biotechnological Innovations of Potato for Enhanced Nutrition

  2024cites this paper
• Early Generation Selection of Potato Breeding Lines

  2024cites this paper
• An Integrated Approach for Biofortification of Carotenoids in Cowpea for Human Nutrition and Health

  2024cites this paper
• Perspectives on Developing Natural Colored Cotton Through Carotenoid Biofortification

  2024cites this paper
• Transcriptomic Analysis Reveals the Mechanism of Color Formation in the Peel of an Evergreen Pomegranate Cultivar ‘Danruo No.1’ During Fruit Development

  2024cites this paper
• Elevated zeaxanthin accumulation in fruit and leaf tissues of orange capsicum: can the leaf be used as a phenotypic marker for selection of high-zeaxanthin fruit?

  2024cites this paper
• Antioxidants of Non-Enzymatic Nature: Their Function in Higher Plant Cells and the Ways of Boosting Their Biosynthesis

  2023cites this paper
• Suppression of ZEAXANTHIN EPOXIDASE 1 restricts stripe rust growth in wheat

  2023cites this paper
• The role of forkhead-associated (FHA)-domain proteins in plant biology

  2023cites this paper
• QTL Mapping of Zeaxanthin Content in Sweet Corn Using Recombinant Inbred Line Population across Different Environments

  2023influential citation
• Engineering Nutritionally Improved Edible Plant Oils.

  2023cites this paper
• Down-regulation of NCED leads to the accumulation of carotenoids in the flesh of F1 generation of peach hybrid

  2022cites this paper
• Enrichment of health-promoting lutein and zeaxanthin in tomato fruit through metabolic engineering

  2022cites this paper
• Does Plant Breeding for Antioxidant-Rich Foods Have an Impact on Human Health?

  2022cites this paper
• Metabolomics and transcriptomics analyses reveal the potential molecular mechanisms of flavonoids and carotenoids in guava pulp with different colors

  2022cites this paper
• Resequencing of sweetpotato germplasm resources reveals key loci associated with multiple agronomic traits

  2022cites this paper
• Roles of Abscisic Acid and Gibberellins in Stem/Root Tuber Development

  2022influential citation
• Carotenoids Fortification

  2021cites this paper
• Comparative transcriptome analysis reveals that chlorophyll metabolism contributes to leaf color changes in wucai (Brassica campestris L.) in response to cold

  2021cites this paper
• Improving Potato Quality: A Problem of Definition and Measurement

  2021cites this paper
• Accumulation of Carotenoids and Expression of Carotenoid Biosynthesis Genes in Fruit Flesh During Fruit Development in Two Cucurbita maxima Inbred Lines

  2021cites this paper
• Metabolic engineering of astaxanthin pathway and heterologous production in novel organisms

  2021cites this paper
• A Mutation in Zeaxanthin epoxidase Contributes to Orange Coloration and Alters Carotenoid Contents in Pepper Fruit (Capsicum annuum).

  2021cites this paper
• Potato

  2020influential citation
• Carotenoid biofortification in crop plants: citius, altius, fortius.

  2020cites this paper
• Comparative transcriptome analysis implied a ZEP paralog was a key gene involved in carotenoid accumulation in yellow-fleshed sweetpotato

  2020cites this paper
• Recent Updates on Healthy Phytoconstituents in Potato: a Nutritional Depository

  2020cites this paper
• Biofortification of Vegetables

  2020cites this paper
• Toxic effects of heavy metal Cd and Zn on chlorophyll, carotenoid metabolism and photosynthetic function in tobacco leaves revealed by physiological and proteomics analysis.

  2020cites this paper
• Genetically Modified Plants for Nutritionally Improved Food: A Promise Kept?

  2020cites this paper
• Advances in Agri-Food Biotechnology

  2020cites this paper
• Biofortification of Carotenoids in Agricultural and Horticultural Crops

  2020cites this paper
• Proximal composition, bioactive compounds and biorefinery approach in potato tubers ofSolanum tuberosumGroup Phureja: a review

  2020cites this paper
• Microbe-Mediated Genetic Engineering for Enhancement of Nutritional Value in Food Crops

  2020cites this paper
• Carotenoids Biofortification of Sweet Potatoes

  2020cites this paper
• Biofortification of Edible Plants

  2020cites this paper
• Development of zeaxanthin‐rich tomato fruit through genetic manipulations of carotenoid biosynthesis

  2020influential citation
• Biofortification Under Climate Change: The Fight Between Quality and Quantity

  2020cites this paper
• Genetically modified fruit and vegetable - An overview on senescence regulation, postharvest nutraceutical quality preservation and shelf life extension

  2020cites this paper
• Potato Carotenoids

  2020cites this paper
• Enhanced Coproduction of Cell-Bound Zeaxanthin and Secreted Exopolysaccharides by Sphingobium sp. via Metabolic Engineering and Optimized Fermentation.

  2019cites this paper
• Biotechnology for Nutritional and Associated Processing Quality Improvement in Potato

  2019cites this paper
• The Important Role of Potatoes, An Underrated Vegetable Food Crop in Human Health and Nutrition

  2019cites this paper
• Improving the Nutritional Value of Potatoes by Conventional Breeding and Genetic Modification

  2019cites this paper
• Nutritional value of potato (Solanum tuberosum) in hot climates: anthocyanins, carotenoids, and steroidal glycoalkaloids

  2019cites this paper
• Ascertaining the Paradigm of Secondary Metabolism Enhancement through Gene Level Modification in Therapeutic Plants

  2019cites this paper
• Efficient production of saffron crocins and picrocrocin in Nicotiana benthamiana using a virus-driven system

  2019cites this paper
• Provitamin a biofortification in maize through genetic engineering and marker-assisted selection

  2019cites this paper
• Stepwise pathway engineering to the biosynthesis of zeaxanthin, astaxanthin and capsanthin in rice endosperm.

  2019cites this paper
• Provitamin A Biofortification of Durum Wheat through a TILLING Approach

  2019cites this paper
• An Introduction to Plant Pigments in Biology and Commerce

  2018cites this paper
• Elevated carotenoids in staple crops: The biosynthesis, challenges and measures for target delivery

  2018cites this paper
• Prospects and progress in the production of valuable carotenoids: Insights from metabolic engineering, synthetic biology, and computational approaches.

  2018influential citation
• Biofortified Crops Generated by Breeding, Agronomy, and Transgenic Approaches Are Improving Lives of Millions of People around the World

  2018cites this paper
• Application of Genetic Engineering in Vegetable Crops

  2018cites this paper
• RNAi-mediated suppression of three carotenoid-cleavage dioxygenase genes, OsCCD1, 4a, and 4b, increases carotenoid content in rice

  2018cites this paper
• Genetically Modified Plants as Sustainable and Economic Sources for RUTFs

  2018cites this paper
• A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health.

  2018cites this paper
• Provitamin A biofortification of crop plants: a gold rush with many miners.

  2017influential citation
• Development of a Dunaliella tertiolecta Strain with Increased Zeaxanthin Content Using Random Mutagenesis

  2017cites this paper
• Molecular and biochemical characterization of a potato collection with contrasting tuber carotenoid content

  2017cites this paper
• Metabolic engineering of the algal chloroplast for terpenoid production

  2017cites this paper
• Improved fruit α‐tocopherol, carotenoid, squalene and phytosterol contents through manipulation of Brassica juncea 3‐HYDROXY‐3‐METHYLGLUTARYL‐COA SYNTHASE1 in transgenic tomato

  2017cites this paper
• A Study on the Expression of Genes Involved in Carotenoids and Anthocyanins During Ripening in Fruit Peel of Green, Yellow, and Red Colored Mango Cultivars

  2017cites this paper
• Biotechnological Tools to Improve Quality Parameters in Temperate Vegetables

  2017cites this paper
• Influence of Environmental Stress toward Carotenogenesis Regulatory Mechanism through In Vitro Model System

  2017cites this paper
• Molecular mechanisms of carotenoid accumulation in carrots

  2017cites this paper
• Genetic Diversity and Molecular Evolution of a Violaxanthin De-epoxidase Gene in Maize

  2016cites this paper
• Over-expression of StLCYb increases β-carotene accumulation in potato tubers

  2016cites this paper
• Metabolic Regulation of Carotenoid-Enriched Golden Rice Line

  2016cites this paper
• Engineering of the carotenoid pathway in Xanthophyllomyces dendrorhous leading to the synthesis of zeaxanthin

  2016cites this paper
• Potato Proteomics: A New Approach for the Potato Processing Industry

  2016cites this paper
• Road to the future of systems biotechnology: CRISPR-Cas-mediated metabolic engineering for recombinant protein production

  2016cites this paper
• Modern Breeding and Biotechnological Approaches to Enhance Carotenoid Accumulation in Seeds.

  2016cites this paper
• Metabolic Biosynthesis of Potato (Solanum tuberosum l.) Antioxidants and Implications for Human Health

  2016influential citation
• Carotenoids in potatoes – a short overview

  2016cites this paper
• Manipulation of Carotenoid Content in Plants to Improve Human Health.

  2016cites this paper
• Heritability of target bioactive compounds and hydrophilic antioxidant capacity in purple- and red-fleshed tetraploid potatoes

  2016cites this paper
• Potato Diversity and Its Genetic Enhancement

  2016cites this paper
• Fatty Acids and Bioactive Lipids of Potato Cultivars: An Overview.

  2016cites this paper
• Metabolic Engineering in Plants

  2015cites this paper
• Combined transcript, proteome, and metabolite analysis of transgenic maize seeds engineered for enhanced carotenoid synthesis reveals pleotropic effects in core metabolism

  2015cites this paper
• New techniques in molecular biology challenge the assessment of modified organisms

  2015cites this paper
• Carotenoids of biotechnological importance.

  2015cites this paper
• Somatic Genome Manipulation

  2015cites this paper
• Quality and Safety Aspects of Vegetables

  2015cites this paper
• Overexpression of the sweet potato IbOr gene results in the increased accumulation of carotenoid and confers tolerance to environmental stresses in transgenic potato.

  2015cites this paper
• The effect of different concentrations of copper and lead on the morphology and physiology of Hypnea musciformis cultivated in vitro: a comparative analysis

  2015cites this paper
• Metabolic Engineering of Wheat Provitamin A by Simultaneously Overexpressing CrtB and Silencing Carotenoid Hydroxylase (TaHYD).

  2015cites this paper
• Somatic Embryogenesis for Potato ( Solanum tuberosum L.) Improvement

  2015cites this paper
• Carotene Hydroxylase Activity Determines the Levels of Both α-Carotene and Total Carotenoids in Orange Carrots[W]

  2014cites this paper
• Plant carotenoids: genomics meets multi-gene engineering.

  2014cites this paper
• Engineering complex metabolic pathways in plants.

  2014cites this paper