Skeletal overgrowth in transgenic mice that overexpress brain natriuretic peptide.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1998-03-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/PNAS.95.5.2337PMID 9482886PMCID PMC19337
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Simultaneous demonstration of bone alkaline and acid phosphatase activities in plastic-embedded sections and differential inhibition of the activities

  2004cited by this paper
• Regulation of endothelial production of C-type natriuretic peptide in coculture with vascular smooth muscle cells. Role of the vascular natriuretic peptide system in vascular growth inhibition.

  1996cited by this paper
• Brain natriuretic peptide versus atrial natriuretic peptide--physiological and pathophysiological significance in children and adults: a review.

  1996cited by this paper
• Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-Dependent Protein Kinase II

  1996cited by this paper
• C-type natriuretic peptide as an autocrine/paracrine regulator of osteoblast. Evidence for possible presence of bone natriuretic peptide system.

  1996cited by this paper
• C-type Natriuretic Peptide Increases Bone Resorption in 1,25-Dihydroxyvitamin D3-stimulated Mouse Bone Marrow Cultures (*)

  1995cited by this paper
• Reciprocal regulation by cyclic nucleotides of the differentiation of rat osteoblast-like cells and mineralization of nodules.

  1995cited by this paper
• Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene.

  1994cited by this paper
• Metacarpal bone mass in normal and osteoporotic Japanese women using computed X-ray densitometry

  1994cited by this paper
• Autocrine regulation of rat chondrocyte proliferation by natriuretic peptide C and its receptor, natriuretic peptide receptor-B.

  1994cited by this paper
• Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs.

  1993cited by this paper
• Seminal plasma factors that cause large elevations in cellular cyclic GMP are C-type natriuretic peptides.

  1993cited by this paper
• Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system".

  1992cited by this paper
• Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide.

  1992cited by this paper
• Molecular biology and biochemistry of the natriuretic peptide system. I: Natriuretic peptides.

  1992cited by this paper
• Molecular biology and biochemistry of the natriuretic peptide system. II: Natriuretic peptide receptors.

  1992cited by this paper
• Atrial natriuretic factor and related peptide hormones.

  1991cited by this paper
• Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide.

  1991cited by this paper
• Signal transduction by guanylyl cyclases.

  1991cited by this paper
• Differential expression of natriuretic peptide genes in cardiac and extracardiac tissues.

  1991cited by this paper
• Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).

  1991cited by this paper
• Hypertension: pathophysiology, diagnosis, and management: volume 2.

  1990cited by this paper
• Hypotension in transgenic mice expressing atrial natriuretic factor fusion genes.

  1990cited by this paper
• Development of the fetal mouse palate in suspension organ culture.

  1990cited by this paper
• A versatile new mineralized bone stain for simultaneous assessment of tetracycline and osteoid seams.

  1989cited by this paper
• Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee.

  1987cited by this paper
• Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

  1987cited by this paper
• The association of scoliosis and congenital heart defects.

  1975cited by this paper
• The scoliosis of congenital heart disease.

  1972cited by this paper

• Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigation

  2025influential citation
• Celebrating the 100th anniversary of the Japan Endocrine Society: reflecting on my 50 years of hormone research

  2025cites this paper
• Roles of organokines in intervertebral disc homeostasis and degeneration

  2024cites this paper
• The Natriuretic Peptide System: A Single Entity, Pleiotropic Effects

  2023cites this paper
• Guanylyl cyclase‐A phosphorylation decreases cardiac hypertrophy and improves systolic function in male, but not female, mice

  2021cites this paper
• Association of circulating B-type natriuretic peptide with osteoporosis in a Chinese type 2 diabetic population

  2021cites this paper
• Molecular and cellular regulation of intramembranous and endochondral bone formation during embryogenesis

  2020cites this paper
• The Role of Genetically Modified Crops to Agricultural Advancement

  2020cites this paper
• Male mice with elevated C-type natriuretic peptide-dependent guanylyl cyclase-B activity have increased osteoblasts, bone mass and bone strength.

  2020cites this paper
• Endochondral ossification and the evolution of limb proportions

  2020influential citation
• The cGMP system: components and function

  2019cites this paper
• Translational science: Newly emerging science in biology and medicine — Lessons from translational research on the natriuretic peptide family and leptin —

  2019cites this paper
• Analysis of short-term treatment with the phosphodiesterase type 5 inhibitor tadalafil on long bone development in young rats.

  2018cites this paper
• Title Skeletal Analysis of the Long Bone Abnormality (lbab/lbab) Mouse, A Novel Chondrodysplastic C-type Natriuretic Peptide

  2018cites this paper
• Corin is a key regulator of endochondral ossification and bone development via modulation of vascular endothelial growth factor A expression

  2018influential citation
• Longitudinal Growth in Rheumatologic Conditions: Current and Emerging Treatments of Growth Delay in Children with Chronic Autoimmune Diseases

  2018cites this paper
• Role of the protease corin in chondrogenic differentiation of human bone marrow‐derived mesenchymal stem cells

  2018cites this paper
• Current Care and Investigational Therapies in Achondroplasia

  2017cites this paper
• Short stature homeobox‐containing gene duplications in 3.7% of girls with tall stature and normal karyotypes

  2017cites this paper
• The systemic nature of CKD

  2017cites this paper
• Achondroplasia: Development, pathogenesis, and therapy

  2017cites this paper
• Osteocrin: identification, expression, and CRISPR/Cas9 analysis in scale development in teleost

  2017cites this paper
• Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish

  2017cites this paper
• Emerging targeted drug therapies in skeletal dysplasias

  2016cites this paper
• Localization of Brain Natriuretic Peptide Immunoreactivity in Rat Spinal Cord

  2016cites this paper
• C-Type Natriuretic Peptide Analog as Therapy for Achondroplasia.

  2016cites this paper
• A Track Record on SHOX: From Basic Research to Complex Models and Therapy

  2016cites this paper
• Acromesomelic dysplasia, type maroteaux caused by novel loss‐of‐function mutations of the NPR2 gene: Three case reports

  2016cites this paper
• Targeting multidrug resistance proteins and C-type natriuretic peptide to optimise cyclic GMP signalling in cardiovascular disease

  2016cites this paper
• Advances in treatment of achondroplasia and osteoarthritis.

  2016cites this paper
• The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth

  2015cites this paper
• Ularitide: a natriuretic peptide candidate for the treatment of acutely decompensated heart failure.

  2015cites this paper
• Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up.

  2015cites this paper
• Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association.

  2015cites this paper
• Musclin is an activity-stimulated myokine that enhances physical endurance

  2015cites this paper
• Differential response of C-type natriuretic peptide to estrogen and dexamethasone in adult bone.

  2014cites this paper
• NPPB and ACAN, Two Novel SHOX2 Transcription Targets Implicated in Skeletal Development

  2014cites this paper
• SHOX triggers the lysosomal pathway of apoptosis via oxidative stress.

  2014cites this paper
• Molecular, Phenotypic Aspects and Therapeutic Horizons of Rare Genetic Bone Disorders

  2014cites this paper
• Characterization of Two ENU-Induced Mutations Affecting Mouse Skeletal Morphology

  2013influential citation
• A human skeletal overgrowth mutation increases maximal velocity and blocks desensitization of guanylyl cyclase-B.

  2013cites this paper
• The receptor guanylyl cyclase Npr2 regulates the bifurcation of cranial sensory axons

  2013cites this paper
• Functional characterisation of osteosarcoma cell lines and identification of mRNAs and miRNAs associated with aggressive cancer phenotypes

  2013influential citation
• C-Type Natriuretic Peptide (CNP) and Postnatal Linear Growth

  2012cites this paper
• C-Type Natriuretic Peptide (CNP) levels are altered in boys with Klinefelter syndrome.

  2012cites this paper
• Skeletal Analysis of the Long Bone Abnormality (lbab/lbab) Mouse, A Novel Chondrodysplastic C-Type Natriuretic Peptide Mutant

  2012cites this paper
• Brain type natriuretic peptide increases L-type Ca2+ current in atrial myocytes by activating natriuretic peptide receptor A

  2012cites this paper
• FGFR3 targeting strategies for achondroplasia

  2012cites this paper
• cGMP signaling and branching of sensory axons in the spinal cord

  2012cites this paper
• N–terminal prohormone B–type natriuretic peptide, inflammation and the vasculature : exploring the links in a bi–ethnic South African population

  2012cites this paper
• N-terminal prohormone B-type natriuretic peptide and cardiovascular function in Africans and Caucasians: the SAfrEIC study.

  2012cites this paper
• Natriuretic peptides in children: physiology and clinical utility

  2011cites this paper
• NPR-A regulates self-renewal and pluripotency of embryonic stem cells

  2011cites this paper
• BNP is a Novel Regulator of Embryonic Stem Cell Proliferation

  2011influential citation
• The effect of PKG II deficiency on osteoblast-specific gene expression in mice

  2011cites this paper
• Natriuretic peptide system: an overview of studies using genetically engineered animal models

  2011cites this paper
• Expression, purification, and characterisation of nesiritide using an E. coli expression system

  2011cites this paper
• Effect of nutrition on plasma C-type natriuretic peptide forms in adult sheep: evidence for enhanced C-type natriuretic peptide degradation during caloric restriction.

  2010cites this paper
• Effects of cGMP-Dependent Protein Kinase Knockouts

  2010cites this paper
• Utilidad de los biomarcadores plasmáticos en el diagnóstico, tratamiento y pronóstico de la enfermedad cerebrovascular aguda

  2010cites this paper
• C‐type natriuretic peptide: Structural studies, fragment synthesis, and preliminary biological evaluation in human osteosarcoma cell lines

  2010cites this paper
• Achondroplasia: pathogenesis and implications for future treatment

  2010cites this paper
• Increased number of sex chromosomes affects height in a nonlinear fashion: A study of 305 patients with sex chromosome aneuploidy

  2010cites this paper
• Chronically elevated plasma C-type natriuretic peptide level stimulates skeletal growth in transgenic mice.

  2009cites this paper
• ZFP36L3: A unique member of the tristetraprolin family of RNA-binding CCCH tandem zinc finger proteins

  2009cites this paper
• Biosynthesis, physiology and main diagnostic and therapeutic potentials of cardiac natriuretic peptides

  2009cites this paper
• Translational research of novel hormones: lessons from animal models and rare human diseases for common human diseases

  2009cites this paper
• of RNA-Binding CCCH Tandem Zinc Finger Proteins

  2009cites this paper
• Central role of guanylyl cyclase in natriuretic peptide signaling in hypertension and metabolic syndrome

  2009cites this paper
• BNP Signaling Is Crucial For Embryonic Stem Cell Proliferation

  2009cites this paper
• Kyoto University graduate school of medicine: tradition and modernity harmonized

  2009cites this paper
• Systemic administration of C-type natriuretic peptide as a novel therapeutic strategy for skeletal dysplasias.

  2009cites this paper
• Natriuretic peptides: potential modulators of circulatory, renal, respiratory, digestive, endocrine, and central nerve systems and implications of their role in bone remodeling

  2009cites this paper
• Characterization of an associated protein kinase of the BMP type II receptor

  2008cites this paper
• Moving Toward an Understanding of Hormone Replacement Therapy in Adolescent Girls

  2008cites this paper
• Adiponectin Protects Against Angiotensin II–Induced Cardiac Fibrosis Through Activation of PPAR-&agr;

  2008cites this paper
• Nitric oxide, C-type natriuretic peptide and cGMP as regulators of endochondral ossification.

  2008cites this paper
• Plasma amino-terminal pro C-type natriuretic Peptide in the neonate: relation to gestational age and postnatal linear growth.

  2008cites this paper
• Molecular mechanism of natriuretic peptide secretion and adaptation to disease in animal model and clinical practice

  2008cites this paper
• Translational research of natriuretic peptide family

  2007cites this paper
• Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent protein kinase induce interleukin-6 transcription in osteoblasts.

  2007cites this paper
• Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet.

  2007cites this paper
• The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord

  2007cites this paper
• BNP is a transcriptional target of the short stature homeobox gene SHOX.

  2007influential citation
• Overexpression of the C‐type natriuretic peptide (CNP) is associated with overgrowth and bone anomalies in an individual with balanced t(2;7) translocation

  2007cites this paper
• C-type natriuretic peptide regulates cellular condensation and glycosaminoglycan synthesis during chondrogenesis.

  2007cites this paper
• Intact kinase homology domain of natriuretic peptide receptor-B is essential for skeletal development.

  2007cites this paper
• Natriuretic peptide receptor B signaling in the cardiovascular system: protection from cardiac hypertrophy

  2007cites this paper
• Molecular biology of the natriuretic peptide system: implications for physiology and hypertension.

  2007cites this paper
• Osteocrin Is a Specific Ligand of the Natriuretic Peptide Clearance Receptor That Modulates Bone Growth*

  2007cites this paper
• ABCs of Natriuretic Peptides: Growth

  2007cites this paper
• Cardiac endocrine function is an essential component of the homeostatic regulation network: physiological and clinical implications.

  2006cites this paper
• Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functions.

  2006cites this paper
• C-type natriuretic peptide in growth: a new paradigm.

  2006cites this paper
• Role of N-terminal brain natriuretic peptide (N-TproBNP) in scleroderma-associated pulmonary arterial hypertension.

  2006influential citation
• Characterization of human fetal osteoblasts by microarray analysis following stimulation with 58S bioactive gel-glass ionic dissolution products.

  2006cites this paper
• Identification, regulation and anti-proliferative role of the NPR-C receptor in gastric epithelial cells

  2006cites this paper
• Transgenic overexpression of brain natriuretic peptide prevents the progression of diabetic nephropathy in mice

  2006cites this paper
• Paradoxical antagonism of PACAP receptor signaling by VIP in Xenopus oocytes via the type-C natriuretic peptide receptor.

  2006cites this paper
• Inhibition of cGMP-Dependent Protein Kinase Reduces the Response to Sonic Hedgehog in Neuralized Embryoid Bodies

  2006cites this paper