Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Genes & Development

• Publication date

  1996-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/GAD.10.2.233PMID 8566756
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CUS1, a suppressor of cold-sensitive U2 snRNA mutations, is a novel yeast splicing factor homologous to human SAP 145.

  1996cited by this paper
• Sequential recognition of the pre-mRNA branch point by U2AF65 and a novel spliceosome-associated 28-kDa protein.

  1995cited by this paper
• Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae.

  1995cited by this paper
• Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly

  1994cited by this paper
• Pre-mRNA splicing.

  1994cited by this paper
• Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114.

  1994cited by this paper
• Dynamic association of proteins with the pre-mRNA branch region.

  1994cited by this paper
• Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo.

  1994cited by this paper
• Identification and characterization by antisense oligonucleotides of exon and intron sequences required for splicing

  1994cited by this paper
• Interactions between highly conserved U2 small nuclear RNA structures and Prp5p, Prp9p, Prp11p, and Prp21p proteins are required to ensure integrity of the U2 small nuclear ribonucleoprotein in Saccharomyces cerevisiae

  1994cited by this paper
• A novel set of spliceosome‐associated proteins and the essential splicing factor PSF bind stably to pre‐mRNA prior to catalytic step II of the splicing reaction.

  1994cited by this paper
• The prespliceosome components SAP 49 and SAP 145 interact in a complex implicated in tethering U2 snRNP to the branch site.

  1994cited by this paper
• Branch nucleophile selection in pre-mRNA splicing: evidence for the bulged duplex model.

  1994cited by this paper
• Interaction between PRP11 and SPP91 yeast splicing factors and characterization of a PRP9-PRP11-SPP91 complex.

  1993cited by this paper
• Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA.

  1993cited by this paper
• Separation of splicing factor SF3 into two components and purification of SF3a activity.

  1993cited by this paper
• Interactions between PRP9 and SPP91 splicing factors identify a protein complex required in prespliceosome assembly.

  1993cited by this paper
• Interaction of mammalian splicing factor SF3a with U2 snRNP and relation of its 60-kD subunit to yeast PRP9.

  1993cited by this paper
• Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing.

  1992cited by this paper
• Protein components specifically associated with prespliceosome and spliceosome complexes.

  1992cited by this paper
• Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites.

  1992cited by this paper
• Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly.

  1990cited by this paper
• A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly.

  1988cited by this paper
• Presplicing complex formation requires two proteins and U2 snRNP.

  1988cited by this paper
• An ordered pathway of snRNP binding during mammalian pre‐mRNA splicing complex assembly.

  1987cited by this paper
• Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes.

  1986cited by this paper
• Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs.

  1986cited by this paper
• Specific and stable intron-factor interactions are established early during in vitro pre-mRNA splicing.

  1985cited by this paper

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