The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Trends in Cell Biology

• Publication date

  1999-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0962-8924(99)01658-XPMID 10511710
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast.

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• The Drosophila STAM gene homolog is in a tight gene cluster, and its expression correlates to that of the adjacent gene ial.

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• Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p.

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  1998cited by this paper
• Identification and characterization of STK12/Aik2: a human gene related to aurora of Drosophila and yeast IPL1

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• Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast Ipl1 that maps on chromosome 19q13.3-ter.

  1998cited by this paper
• The kinase Eg2 is a component of the Xenopus oocyte progesterone‐activated signaling pathway

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• The Human Homologue of Bub3 Is Required for Kinetochore Localization of Bub1 and a Mad3/Bub1-related Protein Kinase

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• AIR-2: An Aurora/Ipl1-related Protein Kinase Associated with Chromosomes and Midbody Microtubules Is Required for Polar Body Extrusion and Cytokinesis in Caenorhabditis elegans Embryos

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• A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos.

  1998cited by this paper
• AIM‐1: a mammalian midbody‐associated protein required for cytokinesis

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• cDNA cloning, expression, subcellular localization, and chromosomal assignment of mammalian aurora homologues, aurora-related kinase (ARK) 1 and 2.

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• A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

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• Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

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• Protein Kinase Profile of Sperm and Eggs: Cloning and Characterization of Two Novel Testis-Specific Protein Kinases (AIE1, AIE2) Related to Yeast and Fly Chromosome Segregation Regulators

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• Assignment of STK6 to human chromosome 20q13.2-->q13.3 and a pseudogene STK6P to 1q41-->q42.

  1997cited by this paper
• A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

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• ayk1, a novel mammalian gene related to Drosophila aurora centrosome separation kinase, is specifically expressed during meiosis

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• Cell Cycle-dependent Expression and Spindle Pole Localization of a Novel Human Protein Kinase, Aik, Related to Aurora of Drosophila and Yeast Ipl1*

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