AF-2364 [1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: a review of recent data.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Contraception

• Publication date

  2005-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/J.CONTRACEPTION.2005.03.008PMID 16181968
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2004cited by this paper
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  2004cited by this paper
• Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis.

  2004cited by this paper
• Fer Kinase/FerT and Adherens Junction Dynamics in the Testis: An In Vitro and In Vivo Study1

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• Is the Cadherin/Catenin Complex a Functional Unit of Cell-Cell Actin-Based Adherens Junctions in the Rat Testis?1

  2003cited by this paper
• Sertoli-Germ Cell Adherens Junction Dynamics in the Testis Are Regulated by RhoB GTPase via the ROCK/LIMK Signaling Pathway1

  2003influential reference
• Adhering junction dynamics in the testis are regulated by an interplay of beta 1-integrin and focal adhesion complex-associated proteins.

  2003cited by this paper
• Lonidamine Solid Dispersions: In Vitro and In Vivo Evaluation

  2002cited by this paper
• Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development.

  2002cited by this paper
• Two New Male Contraceptives Exert Their Effects by Depleting Germ Cells Prematurely from the Testis1

  2001influential reference
• Reversible Inhibition of Spermatogenesis in Rats Using a New Male Contraceptive, 1-(2,4-Dichlorobenzyl)-Indazole-3-Carbohydrazide1

  2001influential reference
• Interactions between lonidamine and beta- or hydroxypropyl-beta-cyclodextrin.

  1998cited by this paper
• Interactions Between Lonidamine and β-or Hydroxypropyl-β-Cyclodextrin

  1998cited by this paper
• Pharmacokinetics and toxicity of oral and intravenous lonidamine in dogs

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  1996cited by this paper
• Micropurification of Two Human Cerebrospinal Fluid Proteins by High Performance Electrophoresis Chromatography

  1993cited by this paper
• Pharmaceutical Dosage Forms and Drug Delivery Systems

  1990cited by this paper
• Effects of AF 1312/TS and lonidamine on cultured sertoli cells.

  1981cited by this paper
• Effects of AF 1312 TS and lonidamine on mammalian testis. A morphological study.

  1981cited by this paper

• Non-hormonal Contraception: Current and Emerging Targets.

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• Recent Advances in Male Contraception: Where Are We Now? A Review of Literature

  2025cites this paper
• Substitution Effects on the Mechanism of Light-Induced 2,5-Diaryltetrazole-Naphthoquinone 1,3-Dipolar Cycloaddition: A Theoretical Study

  2023cites this paper
• Cell-Cell Interaction-Mediated Signaling in the Testis Induces Reproductive Dysfunction—Lesson from the Toxicant/Pharmaceutical Models

  2022cites this paper
• IMPENDING CONTRACEPTIVES THAT MIGHT BE A POSITIVE METHODOLOGY TOWARDS THE MALE CONTRACEPTION

  2022cites this paper
• Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier

  2022cites this paper
• Physiological Characterization of the Transporter-Mediated Uptake of the Reversible Male Contraceptive H2-Gamendazole Across the Blood-Testis Barrier

  2022cites this paper
• Population Briefs, Vol. 11, no. 2

  2022cites this paper
• Signaling Proteins That Regulate Spermatogenesis Are the Emerging Target of Toxicant-Induced Male Reproductive Dysfunction

  2021cites this paper
• mTORC1/rpS6 and p-FAK-Y407 signaling regulate spermatogenesis: Insights from studies of the adjudin pharmaceutical/toxicant model.

  2021cites this paper
• Spermiation: Insights from Studies on the Adjudin Model.

  2021cites this paper
• AKAP9 supports spermatogenesis through its effects on microtubule and actin cytoskeletons in the rat testis

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• Modulating the Blood-Testis Barrier Towards Increasing Drug Delivery.

  2020cites this paper
• Bioactive fragments of laminin and collagen chains - Lesson from the testis.

  2020cites this paper
• Reversible male contraceptives: Current progress

  2020cites this paper
• Microtubule-associated proteins (MAPs) in microtubule cytoskeletal dynamics and spermatogenesis.

  2020cites this paper
• Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier

  2020cites this paper
• The non-hormonal male contraceptive adjudin exerts its effects via MAPs and signaling proteins mTORC1/rpS6 and FAK-Y407.

  2020cites this paper
• F5-peptide enhances the efficacy of the non-hormonal male contraceptive adjudin.

  2019cites this paper
• mTORC1/rpS6 and spermatogenic function in the testis - insights from the adjudin model.

  2019cites this paper
• mTORC1/rpS6 signaling complex that modifies BTB transport function - an in vivo study using the adjudin model.

  2019influential citation
• Adjudin synergizes with paclitaxel and inhibits cell growth and metastasis by regulating the sirtuin 3–Forkhead box O3a axis in human small‐cell lung cancer

  2019cites this paper
• Crosstalk between Sertoli and Germ Cells in Male Fertility.

  2019cites this paper
• Regulation of BTB dynamics in spermatogenesis - insights from the adjudin toxicant model.

  2019cites this paper
• F5-peptide and mTORC1/rpS6 effectively enhance BTB transport function in the testis - lesson from the adjudin model.

  2019cites this paper
• Male Contraceptives

  2018cites this paper
• Recent Developments in Male Contraception

  2018cites this paper
• Environmental toxicants and cell polarity in the testis.

  2018cites this paper
• Sperm Release at Spermiation Is Regulated by Changes in the Organization of Actin- and Microtubule-Based Cytoskeletons at the Apical Ectoplasmic Specialization—A Study Using the Adjudin Model

  2017cites this paper
• Can the evolution of male contraception lead to a revolution? Review of the current state of knowledge

  2017cites this paper
• Drebrin and Spermatogenesis.

  2017cites this paper
• Male Contraceptives : Present and Future Approaches

  2017cites this paper
• Cell polarity, cell adhesion, and spermatogenesis: role of cytoskeletons

  2017cites this paper
• REVERSIBLE CONTRACEPTIVE POTENTIAL OF HARAD IN MALE ALBINO MICE

  2016cites this paper
• Effective Delivery of Male Contraceptives Behind the Blood-Testis Barrier (BTB) - Lesson from Adjudin.

  2016cites this paper
• Non-hormonal male contraception: A review and development of an Eppin based contraceptive.

  2016cites this paper
• Vasectomy; Sperm switch Intra-Vas Approaches to Control Male Fertility

  2016cites this paper
• Mammalian target of rapamycin complex (mTOR) pathway modulates blood-testis barrier (BTB) function through F-actin organization and gap junction.

  2016cites this paper
• Connexin 43 reboots meiosis and reseals blood‐testis barrier following toxicant‐mediated aspermatogenesis and barrier disruption

  2016cites this paper
• Regulation of blood-testis barrier by actin binding proteins and protein kinases.

  2016cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
• Novel Insights into the Downstream Pathways and Targets Controlled by Transcription Factors CREM in the Testis

  2012cites this paper
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  2012cites this paper
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  2010cites this paper
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