Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schönlein purpura nephritis.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Kidney International

• Publication date

  2011-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/ki.2011.16PMID 21326171PMCID PMC3641561
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Galactose-deficient IgA1 in African Americans with IgA nephropathy: serum levels and heritability.

  2010influential reference
• Genetic studies of IgA nephropathy: past, present, and future

  2010influential reference
• IgA nephropathy--the case for a genetic basis becomes stronger.

  2010cited by this paper
• Familial IgA nephropathy in southeastern Kentucky.

  2010influential reference
• Effects of Heritability, Shared Environment, and Nonshared Intrauterine Conditions on Child and Adolescent BMI

  2010cited by this paper
• Genetic Epidemiology of BMI and Body Mass Change From Adolescence to Young Adulthood

  2010cited by this paper
• The Impact of Pedigree Structure on Heritability Estimates

  2009cited by this paper
• Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity.

  2009cited by this paper
• Aberrant galactosylation of IgA1 is involved in the genetic susceptibility of Chinese patients with IgA nephropathy.

  2009influential reference
• Quantitative immunoglobulins in adulthood.

  2009cited by this paper
• Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci

  2009cited by this paper
• Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy.

  2008influential reference
• IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1.

  2008cited by this paper
• Role of Aberrant Glycosylation of IgA1 Molecules in the Pathogenesis of IgA Nephropathy

  2008cited by this paper
• Increasing Heritability of BMI and Stronger Associations With the FTO Gene Over Childhood

  2008cited by this paper
• Serum under-galactosylated IgA1 is increased in Japanese patients with IgA nephropathy.

  2008cited by this paper
• The genetics of IgA nephropathy

  2007cited by this paper
• Serum levels of galactose-deficient IgA in children with IgA nephropathy and Henoch-Schönlein purpura

  2007influential reference
• Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels.

  2007cited by this paper
• Reactivities of N-acetylgalactosamine-specific lectins with human IgA1 proteins.

  2007cited by this paper
• IgA nephropathy and Henoch-Schoenlein purpura nephritis: aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells.

  2007cited by this paper
• Pediatric IgA nephropathies: clinical aspects and therapeutic approaches.

  2004cited by this paper
• Organizational Principles to Guide and Define the Child Health Care System and / or Improve the Health of All Children Committee on Nutrition Prevention of Pediatric Overweight and Obesity

  2003cited by this paper
• Familial cases of Berger's disease and anaphylactoid purpura.

  2001influential reference
• Intercapillary deposits of IgA-IgC.

  2000cited by this paper
• Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies.

  1999cited by this paper
• Henoch-Schönlein purpura in children. Report of 100 patients and review of the literature.

  1999cited by this paper
• A More Accurate Method To Estimate Glomerular Filtration Rate from Serum Creatinine: A New Prediction Equation

  1999cited by this paper
• Abnormal IgA glycosylation in Henoch-Schönlein purpura restricted to patients with clinical nephritis.

  1998influential reference
• Multipoint quantitative-trait linkage analysis in general pedigrees.

  1998cited by this paper
• Multipoint oligogenic linkage analysis of quantitative traits

  1997cited by this paper
• Reference intervals for immunoglobulins IgA, IgG and IgM in serum in adults and in children aged 6 months to 14 years.

  1990cited by this paper
• The commonest glomerulonephritis in the world: IgA nephropathy.

  1987cited by this paper
• Berger disease: Henoch-Schönlein syndrome without the rash.

  1985cited by this paper
• Familial IgA nephropathy. Evidence of an inherited mechanism of disease.

  1985cited by this paper
• A simple estimate of glomerular filtration rate in full-term infants during the first year of life.

  1984cited by this paper
• Serum immunoglobulin concentrations in preschool children measured by laser nephelometry: reference ranges for IgG, IgA, IgM.

  1983cited by this paper
• Reference intervals for serum IgG, IgA, IgM, C3, and C4 as determined by rate nephelometry.

  1982cited by this paper
• A possible relationship between Henoch-Schonlein syndrome and IgA nephropathy (Berger's disease). An illustrative case.

  1978cited by this paper
• A Possible Relationship between Henoch-Schonlein Syndrome and IgA Nephropathy (Berger’s Disease)

  1978cited by this paper
• Primary IgA glomerulonephritis and Schönlein-Henoch purpura nephritis: Clinicopathological and immunohistological characteristics.

  1978cited by this paper
• Heritability in retrospect.

  1977cited by this paper
• Glomerular Deposition of Properdin in Henoch-Schönlein Syndrome and Idiopathic Focal Nephritis

  1973cited by this paper
• IgA glomerular deposits in renal disease.

  1969cited by this paper
• [Intercapillary deposits of IgA-IgG].

  1968cited by this paper

• Néphropathies à IgA (vascularite à IgA et néphropathie à IgA)

  2026cites this paper
• Emerging Biochemical and Immunologic Mechanisms in the Pathogenesis of IgA Nephropathy.

  2025cites this paper
• IgA Vasculitis and IgA Nephropathy: Two Sides of the Same Coin?

  2025cites this paper
• Clinicopathological features and renal outcomes in patients with IgA nephropathy secondary to psoriasis

  2025cites this paper
• Optimal drug treatment for children with IgA vasculitis nephritis: a systematic review and network meta-analysis

  2025cites this paper
• ULBP5 mediates the pathogenesis of Henoch-Schönlein Purpura by modulating endothelial cell proliferation and migration.

  2025cites this paper
• Neutrophils and NETs in kidney disease

  2025cites this paper
• Kidney injury and colocalization of complement C3, IgA, and IgG in glomerular immune-complex deposits of patients with IgA nephropathy or IgA vasculitis with nephritis.

  2025cites this paper
• Engineering of anticancer human immunoglobulin A equipped with albumin for enhanced plasma half-life

  2025cites this paper
• The Genetics of IgA Nephropathy: Implications for Future Therapies.

  2025cites this paper
• Guidelines for the diagnosis and management of childhood immunoglobulin A vasculitis

  2025cites this paper
• The Immunoglobulin A Nephropathy Renaissance: From Pathogenesis to Personalized Therapy

  2025cites this paper
• Modern Biomarkers in IgA Nephropathy and Their Potential in Paediatric Research

  2025cites this paper
• Efficacy and safety of telitacicept in children with IgA vasculitis and IgA vasculitis nephritis: a single-center retrospective study

  2025cites this paper
• IgA Vasculitis Across the Ages: Is It Time for a Precision Medicine Approach?

  2025cites this paper
• Immunoglobulin A vasculitis: The clinical features and pathophysiology

  2024cites this paper
• Inflammatory Bowel Diseases and Nephropathies: Exploring the Gut–Kidney Axis

  2024cites this paper
• Adult-Onset IgA Vasculitis Complicated by Kidney Failure at Disease Onset in a Nepalese Patient: A Case Report

  2024cites this paper
• Correlation of Serum Galactose-Deficient IgA1 and Oxford Class in Cases of IgA Nephropathy.

  2024cites this paper
• Machine learning-based diagnostic prediction of IgA nephropathy: model development and validation study

  2024cites this paper
• IgA Vasculitis (Henoch–Schönlein Purpura): An Update on Treatment

  2024cites this paper
• O-glycosylation of IgA1 and the pathogenesis of an autoimmune disease IgA nephropathy.

  2024cites this paper
• Navigating Adult-Onset IgA Vasculitis-Associated Nephritis

  2024cites this paper
• Efficacy and Safety of Telitacicept as an Add-On Therapy for Refractory Immunoglobulin A Nephropathy or Immunoglobulin A Vasculitis Nephropathy in Children

  2024cites this paper
• Ang-1, Ang-2, and Tie2 are diagnostic biomarkers for Henoch-Schönlein purpura and pediatric-onset systemic lupus erythematous

  2024cites this paper
• Clinical Application of Polygenic Risk Score in IgA Nephropathy

  2024cites this paper
• Genetics of IgA nephrology: risks, mechanisms, and therapeutic targets

  2024cites this paper
• New Progress in the Treatment of IgA Nephropathy

  2023cites this paper
• Pathophysiology and clinical manifestations of immune complex vasculitides

  2023cites this paper
• IgA Nephropathy: Pleiotropic impact of Epstein-Barr virus infection on immunopathogenesis and racial incidence of the disease

  2023cites this paper
• Viral Infections May Be Associated with Henoch–Schönlein Purpura

  2023cites this paper
• Serum galactose-deficient immunoglobulin A1 in recurrent immunoglobulin a nephropathy after kidney transplantation: A meta-analysis.

  2023cites this paper
• Influence of IgA nephropathy on the progression of pulpitis and apical periodontitis in HIGA mice.

  2023cites this paper
• GalNAc-T14 may Contribute to Production of Galactose-Deficient Immunoglobulin A1, the Main Autoantigen in IgA Nephropathy

  2023cites this paper
• An Update on the Genetics of IgA Nephropathy

  2023cites this paper
• Glomerulonephritis.

  2023cites this paper
• New Horizons in IgA Nephropathy: A Focus on Current Treatment and Emerging Solutions

  2023cites this paper
• Present and Future of IgA Nephropathy and Membranous Nephropathy Immune Monitoring: Insights from Molecular Studies

  2023cites this paper
• Diagnostic and prognostic value of galactose-deficient IgA1 in patients with IgA nephropathy: an updated systematic review with meta-analysis

  2023cites this paper
• IgA nephropathy

  2023cites this paper
• The Beneficial Effect of Three-month Induction Therapy with High-dose Prednisone and Mycophenolate Mofetil Followed by Maintenance Therapy in Acute Non-crescentic Nephritis Associated with Immunoglobulin A Deposition Disease in Adults.

  2023cites this paper
• Randomized Phase 2 Trial of Telitacicept in Patients With IgA Nephropathy With Persistent Proteinuria

  2022cites this paper
• IgA nephropathy pathogenesis and therapy: Review & updates

  2022influential citation
• IgA vasculitis update: Epidemiology, pathogenesis, and biomarkers

  2022cites this paper
• Bibliometric analysis of IgA vasculitis nephritis in children from 2000 to 2022

  2022cites this paper
• Characteristics and Roles of T Follicular Helper Cells in SARS-CoV-2 Vaccine Response

  2022cites this paper
• Bibliometric Analysis of Research Relating to IgA Nephropathy from 2010 to 2021

  2022cites this paper
• Increased CD8+ T cells in patients with Henoch-Schonlein purpura nephritis exhibit suppressive immune activity.

  2022cites this paper
• IgA vasculitis with severe renal manifestation

  2022cites this paper
• Development and Validation of a Differential Diagnosis Model for Acute Appendicitis and Henoch-Schonlein Purpura in Children

  2022influential citation
• An Unusual Etiology of Proteinuria and Hematuria in a Case with IgA Vasculitis Nephropathy: Nutcracker Syndrome

  2022cites this paper
• Phosphatase control of cytokine-mediated overproduction of galactose-deficient IgA1, the main autoantigen in IgA nephropathy

  2022cites this paper
• Causal association between inflammatory bowel disease and IgA nephropathy: A bidirectional two-sample Mendelian randomization study

  2022cites this paper
• New Insights and Challenges Associated With IgA Vasculitis and IgA Vasculitis With Nephritis—Is It Time to Change the Paradigm of the Most Common Systemic Vasculitis in Childhood?

  2022cites this paper
• IgA nephropathy: analysis of progression in pediatric patients

  2021cites this paper
• HLA-DQ and HLA-DRB1 alleles associated with Henoch-Schönlein purpura nephritis in Finnish pediatric population: a genome-wide association study

  2021cites this paper
• Interaction between G ALNT12 and C1GALT1 Associates with Galactose-Deficient IgA1 and IgA Nephropathy.

  2021cites this paper
• IgA Vasculitis with Nephritis in Adults: Histological and Clinical Assessment

  2021cites this paper
• Pathogenesis of IgA Vasculitis: An Up-To-Date Review

  2021cites this paper
• Immunoglobulin A, an Active Liaison for Host-Microbiota Homeostasis

  2021cites this paper
• Rapidly progressive IgA vasculitis-associated nephritis successfully treated with immunosuppressive therapy in an adolescent with chronic granulomatous disease

  2021cites this paper
• Pathogenesis of IgA Nephropathy: Current Understanding and Implications for Development of Disease-Specific Treatment

  2021cites this paper
• Vascularite à immunoglobulines A (purpura rhumatoïde)

  2021cites this paper
• Immunoglobulin A Glycosylation and Its Role in Disease.

  2021cites this paper
• Immunoglobulin A Nephropathy in Children

  2021cites this paper
• Aberrantly Glycosylated IgA1 in IgA Nephropathy: What We Know and What We Don’t Know

  2021cites this paper
• High levels of gut-homing immunoglobulin A + B lymphocytes support the pathogenic role of intestinal mucosal hyperresponsiveness in immunoglobulin A nephropathy patients

  2021cites this paper
• Association of Low Serum Complement 3 with Worse Glomerular Filtration Rate in Patients with IgA Nephropathy Secondary to Psoriasis

  2021cites this paper
• Management of IgA Vasculitis with Nephritis

  2021cites this paper
• New susceptible locus, rs9428555, is associated with pediatric-onset immunoglobulin A nephropathy and immunoglobulin A vasculitis in Koreans

  2021cites this paper
• Acute appendicitis as the first manifestation of HenochSchönlein purpura

  2021cites this paper
• Predictability of the Oxford classification of IgA nephropathy in Henoch–Schonlein purpura nephritis

  2021cites this paper
• IgA Vasculitis and IgA Nephropathy: Same Disease?

  2021cites this paper
• Comparison of clinical, pathological and long-term renal outcomes of children with Henoch–Schonlein purpura nephritis and IgA nephropathy

  2021cites this paper
• IgA vasculitis with nephritis: update of pathogenesis with clinical implications

  2021cites this paper
• C1GALT1 in health and disease

  2021cites this paper
• IgA vasculitis nephritis clinical course and kidney biopsy – national study in children

  2021cites this paper
• GWAS-Based Discoveries in IgA Nephropathy, Membranous Nephropathy, and Steroid Sensitive Nephrotic Syndrome.

  2020cites this paper
• Glomerular galactose-deficient IgA1 expression analysis in pediatric patients with glomerular diseases

  2020cites this paper
• Necrotizing Arteritis and Small-Vessel Vasculitis

  2020cites this paper
• Serum levels of galactose-deficient IgA1 in Chinese children with IgA nephropathy, IgA vasculitis with nephritis, and IgA vasculitis

  2020cites this paper
• Plasma galactose-deficient immunoglobulin A1 and loss of kidney function in patients with immunoglobulin A vasculitis nephritis.

  2020cites this paper
• Immune characteristics of renal allograft donors with mesangial IgA deposition.

  2020cites this paper
• Use of liquid chromatography-tandem mass spectrometry to perform urinary proteomic analysis of children with IgA nephropathy and Henoch-Schönlein purpura nephritis.

  2020cites this paper
• Pathophysiology and therapy of systemic vasculitides

  2020cites this paper
• Clinical Significance of Serum Galactose-Deficient IgA1 Level in Children with IgA Nephropathy

  2020influential citation
• Long-Term Risk of Comorbidity after IgA Vasculitis in Childhood: A Population-Based Cohort Study

  2020cites this paper
• IgA nephropathy in children and in adults: two separate entities or the same disease?

  2020cites this paper
• Toward a Clearer Picture of IgA Nephropathy in Spondyloarthritis

  2020cites this paper
• [Expression and significance of follicular helper T cells and galactose-deficient IgA1 in children with Henoch-Schönlein purpura].

  2020influential citation
• The Efficacy and Safety of Integrated Chinese Plus Western Medicine Compared with Western Medicine Alone in the Treatment for Purpuric Nephritis: A Meta-Aalysis

  2020cites this paper
• New therapeutic perspectives for IgA nephropathy in children

  2020cites this paper
• Characteristics of the course of nephritis associated with Iga-vasculitis Henoch-Schoenlein in children

  2020cites this paper
• Role of Epstein-Barr Virus in Pathogenesis and Racial Distribution of IgA Nephropathy

  2020cites this paper
• Evaluation of the Oxford classification in immunoglobulin A vasculitis with nephritis: a cohort study and meta-analysis

  2020cites this paper
• High levels of gut-homing immunoglobulin A+ B lymphocytes support the pathogenic role of intestinal mucosal hyperresponsiveness in immunoglobulin A nephropathy patients

  2020cites this paper
• Endocapillary Proliferation was Associated with Unfavorable Outcomes in Children with Henoch-Schönlein Purpura Nephritis and IgA Nephropathy

  2020cites this paper
• High levels of gut-homing immunoglobulin A–positive þ B lymphocytes support the pathogenic role of intestinal mucosal hyperresponsiveness in immunoglobulin A nephropathy patients

  2020cites this paper
• IgA vasculitis nephritis in children and adults: one or different entities?

  2020cites this paper
• Spectrums and Prognosis of Kidney Disease in Patients with Ankylosing Spondylitis

  2020cites this paper