Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

W. Xiong,Tanxing Cui,Kejun Cheng,Fei Yang,Shao-Rui Chen,D. Willenbring,Y. Guan,H. Pan,Ke Ren,Yan Xu,Li Zhang

Published 2012 in Journal of Experimental Medicine

ABSTRACT

Systemic and intrathecal administration of derivatives of a nonpsychoactive component of marijuana significantly suppresses chronic inflammatory and neuropathic pain, without causing analgesic tolerance, in several rodent models.

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