VITAMIN E DEFICIENCY IN THE MONKEY

Eight young rhesus monkeys were fed a purified diet devoid of vitamin E. After from 6 to 13 months of feeding, all the animals developed signs of vitamin E deficiency. The signs of vitamin E deficiency in the monkey include muscular dystrophy, elevated excretion of creatine, allantoin, and free amino acids and decreased excretion of creatinine. The vitamin E-deficient monkeys all developed anemia and granulocytosis. Anemia was the first sign of vitamin E deficiency which was observed. All of these signs of vitamin E deficiency were reversed by treatment with α-tocopherol.

• Publication year

  1957

• Venue

  Journal of Experimental Medicine

• Publication date

  1957-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/JEM.105.5.395PMID 13428910PMCID 2136703
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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