Alternative Splicing of RNA Triplets Is Often Regulated and Accelerates Proteome Evolution

R. Bradley,J. Merkin,Nicole J. Lambert,C. Burge

Published 2012 in PLoS Biology

ABSTRACT

Inclusion or exclusion of single codons at the splice acceptor site of mammalian genes is regulated in a tissue-specific manner, is strongly conserved, and is associated with local accelerated protein evolution.

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