Mitochondrial Free Radical Production and Aging in Mammals and Birds a

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Annals of the New York Academy of Sciences

• Publication date

  1998-11-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1111/j.1749-6632.1998.tb09905.xPMID 9928433
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Longevity and antioxidant enzymes, non-enzymatic antioxidants and oxidative stress in the vertebrate lung: a comparative study

  2004cited by this paper
• Localization at Complex I and Mechanism of the Higher Free Radical Production of Brain Nonsynaptic Mitochondria in the Short-Lived Rat Than in the Longevous Pigeon

  1998cited by this paper
• Heart and Brain OXO8dG in the Genomic DNA of Rats and Pigeons and Maximum Longevity

  1998cited by this paper
• ADP-Regulation of Mitochondrial Free Radical Production Is Different with Complex I- or Complex II-Linked Substrates: Implications for the Exercise Paradox and Brain Hypermetabolism

  1997cited by this paper
• Dependence of H2O2 Formation by Rat Heart Mitochondria on Substrate Availability and Donor Age

  1997cited by this paper
• Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon.

  1997cited by this paper
• Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from long-lived species: the pigeon and human case.

  1996cited by this paper
• Oxidative Stress, Caloric Restriction, and Aging

  1996cited by this paper
• Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system.

  1995cited by this paper
• THE EVOLUTION OF AVIAN SENESCENCE PATTERNS : IMPLICATIONS FOR UNDERSTANDING PRIMARY AGING PROCESSES

  1995cited by this paper
• Formation of 8-hydroxyguanine in DNA by aging and oxidative stress

  1995cited by this paper
• Mitochondrial DNA mutations associated with aging and degenerative diseases.

  1995cited by this paper
• Modulation of oxidative stress as a means of life-prolonging action of dietary restriction

  1995cited by this paper
• Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds.

  1994cited by this paper
• A decrease of free radical production near critical targets as a cause of maximum longevity in animals.

  1994cited by this paper
• Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse.

  1994cited by this paper
• Life span in birds and the ageing theory of absolute metabolic scope

  1993cited by this paper
• Brain glutathione reductase induction increases early survival and decreases lipofuscin accumulation in aging frogs

  1993cited by this paper
• Simultaneous induction of sod, glutathione reductase, GSH, and ascorbate in liver and kidney correlates with survival during aging.

  1993cited by this paper
• Comparison of mitochondrial pro-oxidant generation and anti-oxidant defenses between rat and pigeon: possible basis of variation in longevity and metabolic potential.

  1993cited by this paper
• Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species.

  1993cited by this paper
• Maximum life span in vertebrates: relationship with liver antioxidant enzymes, glutathione system, ascorbate, urate, sensitivity to peroxidation, true malondialdehyde, in vivo H2O2, and basal and maximum aerobic capacity.

  1993cited by this paper
• Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population.

  1993cited by this paper
• Relationship between antioxidants, lipid peroxidation and aging.

  1992cited by this paper
• An analysis of the role of coenzyme Q in free radical generation and as an antioxidant.

  1992cited by this paper
• Poly(ADP-ribosyl)ation: its role in inducible DNA amplification, and its correlation with the longevity of mammalian species.

  1992cited by this paper
• The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster.

  1992cited by this paper
• Mitochondrial production of oxygen free radicals in the heart muscle during the life span of the rat: peak at middle age.

  1992cited by this paper
• Age-related change of free radical generation in liver and sex glands of rats.

  1992cited by this paper
• Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology.

  1991cited by this paper
• An integrated theory of aging as the result of mitochondrial-DNA mutation in differentiated cells.

  1991cited by this paper
• Aging and lung antioxidant enzymes, glutathione, and lipid peroxidation in the rat.

  1991cited by this paper
• Antioxidants and aging.

  1991cited by this paper
• Phenotypic consequences of copper-zinc superoxide dismutase overexpression in Drosophila melanogaster.

  1990cited by this paper
• Anti-oxidant defences and peroxidation in liver and brain of aged rats.

  1990cited by this paper
• Hydrogen peroxide production by liver mitochondria in different species.

  1990cited by this paper
• Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

  1990cited by this paper
• Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span.

  1990cited by this paper
• Superoxide anion radical production in different animal species.

  1989cited by this paper
• Do mitochondrial DNA fragments promote cancer and aging?

  1988cited by this paper
• Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

  1988cited by this paper
• Oxidative damage to DNA: relation to species metabolic rate and life span.

  1988cited by this paper
• Scaling: Why Is Animal Size So Important?

  1986cited by this paper
• The mitochondrial site of superoxide formation.

  1986cited by this paper
• Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria.

  1985cited by this paper
• The comparative biology of longevity and lifetime energetics.

  1985cited by this paper
• CHAPTER 11 – Antioxidants, Aging, and Longevity

  1984cited by this paper
• Correlation between ultraviolet-induced DNA repair in primate lymphocytes and fibroblasts and species maximum achievable life span.

  1984cited by this paper
• Inverse correlation between species life span and specific cytochrome P-448 content of cultured fibroblasts.

  1982cited by this paper
• Hepatic glutathione S-transferases: activities and cellular localization in rat, rhesus monkey, chimpanzee and man.

  1981cited by this paper
• The relationship of DNA excision repair of ultraviolet-induced lesions to the maximum life span of mammals.

  1981cited by this paper
• Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria.

  1980cited by this paper
• Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species.

  1980cited by this paper
• NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH-ubiquinone reductase preparation.

  1979cited by this paper
• Species, tissue and subcellular distribution of non Se-dependent glutathione peroxidase activity.

  1978cited by this paper
• DNA replication by a membrane-DNA complex from rat liver mitochondria.

  1977cited by this paper
• Role of ubiquinone in the mitochondrial generation of hydrogen peroxide.

  1976cited by this paper
• GLUTATHIONE PEROXIDASE LEVELS IN BRAIN

  1974cited by this paper
• Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species.

  1974cited by this paper
• The Biologic Clock: The Mitochondria?

  1972cited by this paper
• The cellular production of hydrogen peroxide.

  1972cited by this paper
• Respiratory chain linked H2O2 production in pigeon heart mitochondria

  1971cited by this paper
• Effect of Ethoxyquin on the Longevity of C3H Mice

  1971cited by this paper
• Free radical theory of aging: effect of free radical reaction inhibitors on the mortality rate of male LAF mice.

  1968cited by this paper
• Aging: a theory based on free radical and radiation chemistry.

  1956cited by this paper

• Origins of Avian Hyperactive Mitochondria, Genome Compaction, and Air-Sac Physiology in Early Theropods During the Carnian Pluvial Episode

  2026cites this paper
• High-Fat Diet Anticipates Age-Related Sarcopenia Through Increased Oxidative Stress and Inflammation

  2026cites this paper
• Antioxidant Strategies for Age-Related Oxidative Damage in Dogs

  2025cites this paper
• Autism spectrum disorders and nutritional interventions: dimethylglycine and B-vitamins effects on behaviour, inflammation, microbiota and mitochondria in liver and brain synapses.

  2025cites this paper
• Guidelines for the measurement of oxygen consumption rate in Caenorhabditiselegans

  2025cites this paper
• The relationship between diet, plasma glucose, and cancer prevalence across vertebrates

  2025cites this paper
• Cardiac aging: from hallmarks to therapeutic opportunities.

  2024cites this paper
• Relationships between pesticides, polychlorinated biphenyls, blood parameters and oxidative stress of white stork Ciconia ciconia chicks in Poland

  2024cites this paper
• Deregulation of mitochondrial reverse electron transport alters the metabolism of reactive oxygen species and NAD+/NADH and presents a therapeutic target in Alzheimer’s disease

  2024cites this paper
• Mitochondrial metabolism and neuroinflammation in the cerebral cortex and cortical synapses of rats: effect of milk intake through DNA methylation.

  2024cites this paper
• Goat Milk Supplementation Modulates the Mitochondrial Metabolic Flexibility and Orexin-A Levels Influencing the Inflammatory Pattern in Rats

  2024cites this paper
• Reducing Dietary Polyunsaturated to Saturated Fatty Acids Ratio Improves Lipid and Glucose Metabolism in Obese Zucker Rats

  2023cites this paper
• Phenotypic molecular features of long-lived animal species.

  2023cites this paper
• The relationship between diet, plasma glucose, and cancer prevalence across vertebrates

  2023cites this paper
• Crosstalk between Adipose Tissue and Hepatic Mitochondria in the Development of the Inflammation and Liver Injury during Ageing in High-Fat Diet Fed Rats

  2023cites this paper
• Dietary restriction and life-history trade-offs: insights into mTOR pathway regulation and reproductive investment in Japanese quails

  2023cites this paper
• Hepatocyte Aquaporins AQP8 and AQP9 Are Engaged in the Hepatic Lipid and Glucose Metabolism Modulating the Inflammatory and Redox State in Milk-Supplemented Rats

  2023cites this paper
• Telomeres and telomerase: active but complex players in life-history decisions

  2023cites this paper
• Mitochondrial ROS production, oxidative stress and aging within and between species: Evidences and recent advances on this aging effector.

  2023cites this paper
• The Hepatic Mitochondrial Alterations Exacerbate Meta-Inflammation in Autism Spectrum Disorders

  2022cites this paper
• Altered Mitochondrial Quality Control in Rats with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Induced by High-Fat Feeding

  2022cites this paper
• Ageing Increases Cardiac Electrical Remodelling in Rats and Mice via NOX4/ROS/CaMKII-Mediated Calcium Signalling

  2022cites this paper
• Mitochondrial Aging and Senolytic Natural Products with Protective Potential

  2022cites this paper
• Dietary Micronutrient Management to Treat Mitochondrial Dysfunction in Diet-Induced Obese Mice

  2021cites this paper
• Mitochondrial Reactive Oxygen Species Aging Theory

  2021cites this paper
• An energetics perspective on geroscience: mitochondrial protonmotive force and aging

  2021cites this paper
• How Birds During Migration Maintain (Oxidative) Balance

  2021cites this paper
• Heart Mitochondrial Metabolic Flexibility and Redox Status Are Improved by Donkey and Human Milk Intake

  2021cites this paper
• 5-Hydroxytryptamine Modulates Maturation and Mitochondria Function of Human Oligodendrocyte Progenitor M03-13 Cells

  2021cites this paper
• Mitochondrial Functioning and the Relations among Health, Cognition, and Aging: Where Cell Biology Meets Cognitive Science

  2021cites this paper
• Is the NDUFV2 subunit of the hydrophilic complex I domain a key determinant of animal longevity?

  2021cites this paper
• A new perspective on ROS in aging with an integrated view of the gut microbiota

  2021cites this paper
• Inosine ameliorates the effects of hemin induced oxidative stress in broilers

  2020cites this paper
• Targeting ER stress and calpain activation to reverse age-dependent mitochondrial damage in the heart.

  2020cites this paper
• Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity

  2020cites this paper
• Decreased Metabolic Flexibility in Skeletal Muscle of Rat Fed with a High-Fat Diet Is Recovered by Individual CLA Isomer Supplementation via Converging Protective Mechanisms

  2020cites this paper
• Fewer Exposed Lysine Residues May Explain Relative Resistance of Chicken Serum Albumin to In Vitro Protein Glycation in Comparison to Bovine Serum Albumin

  2020influential citation
• Butyrate as a bioactive human milk protective component against food allergy

  2020cites this paper
• Beyond the Powerhouse: Integrating Mitonuclear Evolution, Physiology, and Theory in Comparative Biology.

  2019cites this paper
• Acute effects of intense exercise on the antioxidant system in birds: does exercise training help?

  2019cites this paper
• Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts

  2019cites this paper
• Milk From Cow Fed With High Forage/Concentrate Ratio Diet: Beneficial Effect on Rat Skeletal Muscle Inflammatory State and Oxidative Stress Through Modulation of Mitochondrial Functions and AMPK Activity

  2019cites this paper
• Plumage redness signals mitochondrial function in the House Finch

  2019cites this paper
• The effect of short-term methionine restriction on glutathione synthetic capacity and antioxidant responses at the whole tissue and mitochondrial level in the rat liver.

  2019cites this paper
• Mitochondrial Reactive Oxygen Species Aging Theory

  2019cites this paper
• Toxicological effects of ciprofloxacin exposure to Drosophila melanogaster.

  2019cites this paper
• A sex chromosome inversion is associated with copy number variation of mitochondrial DNA in zebra finch sperm

  2019cites this paper
• Mitochondria and Ageing

  2018cites this paper
• The Impact of Bacillus subtilis KATMIRA1933 Supplementation on Telomere Length and Mitochondrial DNA Damage of Laying Hens

  2018cites this paper
• The Comparative Biology of Mitochondrial Function and the Rate of Aging.

  2018cites this paper
• Antioxidant Vitamins and Ageing.

  2018cites this paper
• The Effect of High Temperature on Viability, Proliferation, Apoptosis and Anti-oxidant Status of Chicken Embryonic Fibroblast Cells

  2018cites this paper
• Effect of Temperature on Metabolism and Lifespan in Several Homeothermic Animals

  2018cites this paper
• Assessment of the Health Status of Mussels Mytilus galloprovincialis Along the Campania Coastal Areas: A Multidisciplinary Approach

  2018influential citation
• 3,5-Diiodo-L-Thyronine Affects Structural and Metabolic Features of Skeletal Muscle Mitochondria in High-Fat-Diet Fed Rats Producing a Co-adaptation to the Glycolytic Fiber Phenotype

  2018cites this paper
• Different Views on the Tissue Thermogenesis of Organisms

  2018cites this paper
• Human Milk and Donkey Milk, Compared to Cow Milk, Reduce Inflammatory Mediators and Modulate Glucose and Lipid Metabolism, Acting on Mitochondrial Function and Oleylethanolamide Levels in Rat Skeletal Muscle

  2018cites this paper
• Hepatic Mitochondrial Dysfunction and Immune Response in a Murine Model of Peanut Allergy

  2018cites this paper
• Circadian Dysregulation and Melatonin Rhythm Suppression in the Context of Aging

  2017cites this paper
• Chronic Kidney Disease and Hypertensive-Related Complications of Elevated Fibroblast Growth Factor 23

  2017cites this paper
• Butyrate Regulates Liver Mitochondrial Function, Efficiency, and Dynamics in Insulin-Resistant Obese Mice

  2017cites this paper
• Milk from cows fed a diet with a high forage:concentrate ratio improves inflammatory state, oxidative stress, and mitochondrial function in rats.

  2017cites this paper
• Polyphenol‐rich virgin olive oil reduces insulin resistance and liver inflammation and improves mitochondrial dysfunction in high‐fat diet fed rats

  2017cites this paper
• Investigating the role of fractalkine an S1P receptors on oxidative stress in the CNS

  2016cites this paper
• Extremely low frequency electromagnetic fields stimulation modulates autoimmunity and immune responses: a possible immuno-modulatory therapeutic effect in neurodegenerative diseases

  2016cites this paper
• Cellular Energy Metabolism and Oxidative Stress

  2016cites this paper
• Aging is a Group-Selected Adaptation: Theory, Evidence, and Medical Implications

  2016cites this paper
• Mitochondrial Metabolism in Aging Heart.

  2016cites this paper
• The role of the antioxidant system during intense endurance exercise: lessons from migrating birds

  2016influential citation
• Bone-associated gene evolution and the origin of flight in birds

  2016cites this paper
• Polyunsaturated Fatty Acids Attenuate Diet Induced Obesity and Insulin Resistance, Modulating Mitochondrial Respiratory Uncoupling in Rat Skeletal Muscle

  2016cites this paper
• Oxygen in human health from life to death – An approach to teaching redox biology and signaling to graduate and medical students

  2015cites this paper
• The effect of allopurinol administration on mitochondrial respiration and gene expression of xanthine oxidoreductase, inducible nitric oxide synthase, and inflammatory cytokines in selected tissues of broiler chickens.

  2015cites this paper
• Human, donkey and cow milk differently affects energy efficiency and inflammatory state by modulating mitochondrial function and gut microbiota.

  2015cites this paper
• The role of mitochondria in mTOR‐regulated longevity

  2015cites this paper
• Early, But Not Late Onset Estrogen Replacement Therapy Prevents Oxidative Stress and Metabolic Alterations Caused by Ovariectomy

  2014cites this paper
• New data on programmed aging — slow phenoptosis

  2014cites this paper
• Sepsis-induced Cardiac Mitochondrial Damage and Potential Therapeutic Interventions in the Elderly.

  2014cites this paper
• Proteostasis in the long-lived daf-2 mutant of Caenorhabditis elegans: the influence of protein turnover and stability

  2014cites this paper
• Neuronal Cellular Responses to Extremely Low Frequency Electromagnetic Field Exposure: Implications Regarding Oxidative Stress and Neurodegeneration

  2014cites this paper
• Aging and injury: alterations in cellular energetics and organ function.

  2014cites this paper
• Mitochondrial free radical theory of aging: Who moved my premise?

  2014cites this paper
• Life-history Constraints on the Mechanisms that Control the Rate of ROS Production

  2014cites this paper
• Zelluläre Mechanismen des Alterns

  2014cites this paper
• Evolutionary characterization of genes involved in development and adaptation in vertebrates under differential environmental conditions of selective pressure

  2014cites this paper
• The Effect of Allopurinol and Inosine Administration on Xanthine Oxidoreductase Gene Expression, Mitochondrial Respiration, and Inflammation in Broiler Chickens

  2014influential citation
• c 9 , t 11-Conjugated linoleic acid ameliorates steatosis by modulating mitochondrial uncoupling and Nrf 2 pathway

  2014cites this paper
• c9,t11-Conjugated linoleic acid ameliorates steatosis by modulating mitochondrial uncoupling and Nrf2 pathway[S]

  2014cites this paper
• Five Decades with Polyunsaturated Fatty Acids: Chemical Synthesis, Enzymatic Formation, Lipid Peroxidation and Its Biological Effects

  2013cites this paper
• Evaluation of the Physiological Relationship Between Oxidative Stress andMetabolic Characters: Insights From Hybridization Between Anarhichasminor × A. lupus

  2013cites this paper
• Reverse electron flow-mediated ROS generation in ischemia-damaged mitochondria: role of complex I inhibition vs. depolarization of inner mitochondrial membrane.

  2013cites this paper
• Relationships between genotypes and phenotypes in natural populations of the European flounder (Platichthys flesus) under different types of contamination in estuaries

  2013cites this paper
• Concept of Aging as a Result of Slow Programmed Poisoning of an Organism with Mitochondrial Reactive Oxygen Species

  2013cites this paper
• Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa).

  2013cites this paper
• Mitochondrial metabolism in aging: effect of dietary interventions.

  2013cites this paper
• Is carotenoid ornamentation linked to the inner mitochondria membrane potential? A hypothesis for the maintenance of signal honesty.

  2013cites this paper
• Physiology of reproductive senescence in Florida scrub-jays: results from a long-term study and GnRH challenge.

  2013cites this paper
• Enhancing protein disaggregation restores proteasome activity in aged cells

  2013cites this paper
• Why Is There So Much DHA in the Brain, Retina and Testis? Possible Implications for Human Reproduction and the Survival of Our Species

  2013cites this paper
• What is “phenoptosis” and how to fight it?

  2012cites this paper