Neuronal activity of the human subthalamic nucleus in the parkinsonian and nonparkinsonian state.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Neurophysiology

• Publication date

  2008-11-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1152/jn.90574.2008PMID 18701754
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Deep brain stimulation: better quality of life with electricity than with medication].

  2010cited by this paper
• The emerging neuropathology of essential tremor

  2008cited by this paper
• Consensus Statement of the Movement Disorder Society on Tremor

  2008cited by this paper
• Update on surgery for Parkinson's disease

  2007cited by this paper
• Kinematic analysis of thalamic versus subthalamic neurostimulation in postural and intention tremor.

  2007cited by this paper
• Pathological synchronization in Parkinson's disease: networks, models and treatments.

  2007cited by this paper
• Neuronal firing before and after burst discharges in the monkey basal ganglia is predictably patterned in the normal state and altered in parkinsonism.

  2006cited by this paper
• Local shuffling of spike trains boosts the accuracy of spike train spectral analysis.

  2006cited by this paper
• Deep brain stimulation: Preoperative issues

  2006cited by this paper
• Beta oscillatory activity in the subthalamic nucleus and its relation to dopaminergic response in Parkinson's disease.

  2006cited by this paper
• Basal ganglia local field potential activity: character and functional significance in the human.

  2005cited by this paper
• Effect of propofol anesthesia on pallidal neuronal discharges in generalized dystonia.

  2005cited by this paper
• Movement-related changes in synchronization in the human basal ganglia.

  2002cited by this paper
• Synchronized Neuronal Discharge in the Basal Ganglia of Parkinsonian Patients Is Limited to Oscillatory Activity

  2002cited by this paper
• Pathophysiology of nonparkinsonian tremors

  2002cited by this paper
• Pathophysiology of Parkinson's disease: From clinical neurology to basic neuroscience and back

  2002cited by this paper
• Functional anatomy of the basal ganglia

  2002cited by this paper
• Dependence of subthalamic nucleus oscillations on movement and dopamine in Parkinson's disease.

  2002cited by this paper
• From single extracellular unit recording in experimental and human Parkinsonism to the development of a functional concept of the role played by the basal ganglia in motor control.

  2002cited by this paper
• The subthalamic nucleus in Parkinson's disease: somatotopic organization and physiological characteristics.

  2001cited by this paper
• Dopamine Dependency of Oscillations between Subthalamic Nucleus and Pallidum in Parkinson's Disease

  2001cited by this paper
• Subthalamic neuron activity related to tremor and movement in Parkinson's disease

  2000cited by this paper
• Single-unit analysis of the pallidum, thalamus and subthalamic nucleus in parkinsonian patients.

  2000cited by this paper
• High-frequency Synchronization of Neuronal Activity in the Subthalamic Nucleus of Parkinsonian Patients with Limb Tremor

  2000cited by this paper
• Firing Patterns and Correlations of Spontaneous Discharge of Pallidal Neurons in the Normal and the Tremulous 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Vervet Model of Parkinsonism

  2000cited by this paper
• In vivo extracellular electrophysiology of pallidal neurons in dystonic and nondystonic hamsters

  1999cited by this paper
• Profile. Joan Connors, DMin, RD.

  1998cited by this paper
• Neurophysiological identification of the subthalamic nucleus in surgery for Parkinson's disease

  1998cited by this paper
• Physiological aspects of information processing in the basal ganglia of normal and parkinsonian primates

  1998cited by this paper
• Identification and characterization of neurons with tremor-frequency activity in human globus pallidus

  1997cited by this paper
• Increased subthalamic neuronal activity after nigral dopaminergic lesion independent of disinhibition via the globus pallidus.

  1996cited by this paper
• Neurons in the globus pallidus do not show correlated activity in the normal monkey, but phase-locked oscillations appear in the MPTP model of parkinsonism.

  1995cited by this paper
• The functional anatomy of disorders of the basal ganglia.

  1995cited by this paper
• Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidum in basal ganglia circuitry.

  1995cited by this paper
• The primate subthalamic nucleus. I. Functional properties in intact animals.

  1994cited by this paper
• The functions of the basal ganglia and the paradox of stereotaxic surgery in Parkinson's disease.

  1994cited by this paper
• The primate subthalamic nucleus. III. Changes in motor behavior and neuronal activity in the internal pallidum induced by subthalamic inactivation in the MPTP model of parkinsonism.

  1994cited by this paper
• The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism.

  1994cited by this paper
• Reversal of Rigidity and Improvement in Motor Performance by Subthalamic High‐frequency Stimulation in MPTP‐treated Monkeys

  1993cited by this paper
• Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.

  1990cited by this paper
• Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions.

  1990cited by this paper
• Primate models of movement disorders of basal ganglia origin.

  1990cited by this paper
• Bursts and recurrences of bursts in the spike trains of spontaneously active striate cortex neurons.

  1985cited by this paper
• Atlas for Stereotaxy of the Human Brain

  1977cited by this paper

• Precisely-timed outpatient recordings of subcortical local field potentials from wireless streaming-capable deep-brain stimulators: a method and toolbox.

  2025cites this paper
• Intraoperative neural firing correlates with motor and cognitive features in Parkinson's disease.

  2025cites this paper
• Differential synaptic depression mediates the therapeutic effect of deep brain stimulation

  2025cites this paper
• Deep brain implantable microelectrode arrays for detection and functional localization of the subthalamic nucleus in rats with Parkinson’s disease

  2024cites this paper
• NClSilico: A Closed-Loop neuromodulation platform in silico

  2024cites this paper
• Effect of subthalamic and nigral deep brain stimulation on speech and voice in Parkinson’s patients

  2024cites this paper
• A multi-network model of Parkinson’s disease tremor: exploring the finger-dimmer-switch theory and role of dopamine in thalamic self-inhibition

  2024cites this paper
• Subthalamic nucleus synchronization between beta band local field potential and single‐unit activity in Parkinson's disease

  2024cites this paper
• Spontaneous blink-related beta power increase and theta phase reset in subthalamic nucleus of Parkinson patients during walking.

  2024cites this paper
• Brain Networks Involved in Sensory Perception in Parkinson’s Disease: A Scoping Review

  2023cites this paper
• Efficient suppression of parkinsonian beta oscillations in a closed-loop model of deep brain stimulation with amplitude modulation

  2023cites this paper
• Computational study of associations between the synaptic conductance of STN and GPe and the development of Parkinson’s disease

  2023cites this paper
• Control mechanisms of pathological low-frequency oscillations under different targets in Parkinson's disease

  2023cites this paper
• T‐type calcium channels as therapeutic targets in essential tremor and Parkinson's disease

  2023cites this paper
• Combining ultrasound and microelectrode recordings for postoperative localization of subthalamic electrodes in Parkinson's disease.

  2023cites this paper
• Intelligibility of speech in Parkinson's disease relies on anatomically segregated subthalamic beta oscillations.

  2023cites this paper
• Subthalamic and nigral neurons are differentially modulated during parkinsonian gait

  2023cites this paper
• Neural pathway connectivity and discharge changes between M1 and STN in Hemiparkinsonian Rats.

  2023cites this paper
• Transmission of delta band (0.5-4 Hz) oscillations from the globus pallidus to the substantia nigra pars reticulata in dopamine depletion

  2022cites this paper
• Model-based quantitative optimization of deep brain stimulation and prediction of parkinson's states.

  2022cites this paper
• Long-Lasting Desynchronization of Plastic Neuronal Networks by Double-Random Coordinated Reset Stimulation

  2022cites this paper
• Basal ganglia neurons in healthy and parkinsonian primates generate recurring sequences of spikes

  2022cites this paper
• Neurophysiological mechanisms of DBS from a connectomic perspective

  2022cites this paper
• Oscillation suppression effects of intermittent noisy deep brain stimulation induced by coordinated reset pattern based on a computational model

  2022cites this paper
• Adaptive deep brain stimulation: Retuning Parkinson's disease.

  2022cites this paper
• Electrophysiological confrontation of Lead-DBS-based electrode localizations in patients with Parkinson’s disease undergoing deep brain stimulation

  2022cites this paper
• Altered alpha and theta oscillations correlate with sequential working memory in Parkinson’s disease

  2022cites this paper
• Effective suppression of beta oscillation in Parkinsonian state via a noisy direct delayed feedback control scheme*

  2021cites this paper
• Long-Lasting Desynchronization of Plastic Neural Networks by Random Reset Stimulation

  2021cites this paper
• Coordinated Reset Vibrotactile Stimulation Induces Sustained Cumulative Benefits in Parkinson’s Disease

  2021cites this paper
• Conveyance of cortical pacing for parkinsonian tremor-like hyperkinetic behavior by subthalamic dysrhythmia.

  2021cites this paper
• Impaired reach-to-grasp kinematics in parkinsonian patients relates to dopamine-dependent, subthalamic beta bursts

  2021cites this paper
• Short pulse and directional thalamic deep brain stimulation have differential effects in parkinsonian and essential tremor

  2021cites this paper
• Intensity-Varied Closed-Loop Noise Stimulation for Oscillation Suppression in the Parkinsonian State

  2021cites this paper
• Closing the loop of DBS using the beta oscillations in cortex

  2021cites this paper
• Multiple-site deep brain stimulation with delayed rectangular waveforms for Parkinson's disease

  2021cites this paper
• Topographic connectivity and cellular profiling reveal detailed input pathways and functionally distinct cell types in the subthalamic nucleus

  2021cites this paper
• Oscillations of pause-burst neurons in the STN correlate with the severity of motor signs in Parkinson's disease

  2021cites this paper
• Long-Lasting Desynchronization Effects of Coordinated Reset Stimulation Improved by Random Jitters

  2021cites this paper
• Deep learning reveals personalized spatial spectral abnormalities of high delta and low alpha bands in EEG of patients with early Parkinson’s disease

  2021cites this paper
• Local field potential dynamics in the primate cortex in relation to parkinsonism reveled by machine learning: A comparison between the primary motor cortex and the supplementary area.

  2020cites this paper
• Independently together: subthalamic theta and beta opposite roles in predicting Parkinson’s tremor

  2020cites this paper
• Dopaminergic denervation impairs cortical motor and associative/limbic information processing through the basal ganglia and its modulation by the CB1 receptor.

  2020cites this paper
• Parkinson’s Disease: Deep Brain Stimulation

  2020cites this paper
• Gait-related frequency modulation of beta oscillatory activity in the subthalamic nucleus of parkinsonian patients.

  2020cites this paper
• Delta Oscillations Are a Robust Biomarker of Dopamine Depletion Severity and Motor Dysfunction in Awake Mice

  2020cites this paper
• Impact of number of stimulation sites on long-lasting desynchronization effects of coordinated reset stimulation.

  2020cites this paper
• Delta Oscillations Are a Robust Biomarker of Dopamine Depletion Severity and Motor Dysfunction in Awake Mice.

  2020cites this paper
• Neural activity clusterization for estimation of firing pattern.

  2019cites this paper
• Evolving concepts on bradykinesia.

  2019cites this paper
• Evaluation of Spike Sorting Algorithms: Application to Human Subthalamic Nucleus Recordings and Simulations.

  2019influential citation
• Freezing of gait in Parkinson’s disease reflects a sudden derangement of locomotor network dynamics

  2019cites this paper
• Levodopa Modulates Functional Connectivity in the Upper Beta Band Between Subthalamic Nucleus and Muscle Activity in Tonic and Phasic Motor Activity Patterns in Parkinson’s Disease

  2019cites this paper
• Mapping stimulation-induced beneficial and adverse effects in the subthalamic area of essential tremor patients.

  2019cites this paper
• Noise-Induced Improvement of the Parkinsonian State: A Computational Study

  2019cites this paper
• Adaptive Parameter Selection for Deep Brain Stimulation in Parkinson’s Disease

  2019cites this paper
• Suppression of Multimodality in Inter-Spike Interval Distribution: Role of External Damped Oscillatory Input

  2018cites this paper
• Modeling and Analysis of Beta Oscillations in the Basal Ganglia

  2018influential citation
• An integrated system for synchronous detection of neuron spikes and dopamine activities in the striatum of Parkinson monkey brain.

  2018cites this paper
• Histamine and deep brain stimulation: the pharmacology of regularizing a brain.

  2018cites this paper
• Graded 6-OHDA-induced dopamine depletion in the nigrostriatal pathway evokes progressive pathological neuronal activities in the subthalamic nucleus of a hemi-parkinsonian mouse.

  2018cites this paper
• Thalamic short pulse stimulation diminishes adverse effects in essential tremor patients

  2018cites this paper
• Properties of oscillatory neuronal activity in the basal ganglia and thalamus in patients with Parkinson’s disease

  2018cites this paper
• Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications

  2018cites this paper
• Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation.

  2018cites this paper
• Electrical stimulation of the “cribriform” subthalamic nucleus in Parkinson’s disease. Clinical case and review of the literature

  2018cites this paper
• Synchronised spiking activity underlies phase amplitude coupling in the subthalamic nucleus of Parkinson's disease patients

  2018cites this paper
• Neuronal Activity of the Subthalamic Nucleus in Patients with Parkinson’s Disease

  2018cites this paper
• Cyclic AMP‐producing chemogenetic activation of indirect pathway striatal projection neurons and the downstream effects on the globus pallidus and subthalamic nucleus in freely moving mice

  2018cites this paper
• Phase matters: A role for the subthalamic network during gait

  2018cites this paper
• Robust desynchronization of Parkinson’s disease pathological oscillations by frequency modulation of delayed feedback deep brain stimulation

  2018cites this paper
• Evaluation of spike sorting algorithms: Simulations and application to human Subthalamic Nucleus recordings

  2018influential citation
• Classification and Prediction of Clinical Improvement in Deep Brain Stimulation From Intraoperative Microelectrode Recordings

  2017cites this paper
• Neuronal firing activity in the basal ganglia after striatal transplantation of dopamine neurons in hemiparkinsonian rats.

  2017cites this paper
• Dynamics of human subthalamic neuron phase-locking to motor and sensory cortical oscillations during movement.

  2017cites this paper
• Antiarrhythmics cure brain arrhythmia: The imperativeness of subthalamic ERG K+ channels in parkinsonian discharges

  2017cites this paper
• Movement-Related Activity of Human Subthalamic Neurons during a Reach-to-Grasp Task

  2017influential citation
• Optimized temporal pattern of brain stimulation designed by computational evolution

  2017cites this paper
• Hyperbolic Modeling of Subthalamic Nucleus Cells to Investigate the Effect of Dopamine Depletion

  2017cites this paper
• Localization of beta and high-frequency oscillations within the subthalamic nucleus region

  2017cites this paper
• The role of cortical oscillations in a spiking neural network model of the basal ganglia

  2017cites this paper
• Algorithmic design of a noise-resistant and efficient closed-loop deep brain stimulation system: A computational approach

  2017cites this paper
• Decreased Power but Preserved Bursting Features of Subthalamic Neuronal Signals in Advanced Parkinson's Patients under Controlled Desflurane Inhalation Anesthesia

  2017cites this paper
• A Population of Indirect Pathway Striatal Projection Neurons Is Selectively Entrained to Parkinsonian Beta Oscillations

  2017cites this paper
• Unitary synaptic connections among substantia nigra pars reticulata neurons.

  2016cites this paper
• Distinct roles of cortical and pallidal β and γ frequencies in hemiparkinsonian and dyskinetic rats.

  2016cites this paper
• Distinctive neuronal firing patterns in subterritories of the subthalamic nucleus.

  2016influential citation
• Striatal Dopaminergic Innervation Regulates Subthalamic Beta-Oscillations and Cortical-Subcortical Coupling during Movements: Preliminary Evidence in Subjects with Parkinson’s Disease

  2016cites this paper
• Action selection in the rhythmic brain : the role of the basal ganglia and tremor

  2016cites this paper
• Optimal control of directional deep brain stimulation in the parkinsonian neuronal network

  2016cites this paper
• Subthalamic oscillatory activity in parkinsonian patients with off‐period dystonia

  2016cites this paper
• Bilateral Deep Brain Stimulation of the Subthalamic Nucleus under Sedation with Propofol and Fentanyl

  2016cites this paper
• Repetitive Finger Movement, Buttoning and Purdue Pegboard Tasks in People with Parkinson’s Disease

  2016cites this paper
• Exploiting pallidal plasticity for stimulation in Parkinson’s disease

  2015influential citation
• Alterations in neuronal activity in basal ganglia-thalamocortical circuits in the parkinsonian state

  2015cites this paper
• Characteristics of the neuronal firing patterns in the subthalamic nucleus with graded dopaminergic cell loss in the nigrostriatal pathway

  2015cites this paper
• Elevated synchrony in Parkinson disease detected with electroencephalography

  2015cites this paper
• Bursting activity of substantia nigra pars reticulata neurons in mouse parkinsonism in awake and anesthetized states.

  2015cites this paper
• Intraoperative Microelectrode Recording

  2015cites this paper
• Modulation of Microglial Activity by GDNF

  2015cites this paper