Interferon: Immunobiology and Clinical Significance

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Annals of Internal Medicine

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.7326/0003-4819-96-1-80
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• 971 IMPAIRED PRODUCTION OF IMMUNE (PHA-INDUCED) INTERFERON IN NEWBORNS IS DUE TO A FUNCTIONALLY IMMATURE ACROPHAGE

  1981cited by this paper
• Antiviral treatment of chronic hepatitis B virus infection. I. Changes in viral markers with interferon combined with adenine arabinoside.

  1981cited by this paper
• Non-Antiviral Actions of Interferons

  1981cited by this paper
• Human immune interferon: induction in lymphoid cells by a calcium ionophore

  1980cited by this paper
• Differential effect of interferon expression of IgG- and IgM-Fc receptors on human lymphocytes.

  1980cited by this paper
• Relationship between enhanced macrophage phagocytic activity and the induction of interferon by Newcastle disease virus in mice.

  1980cited by this paper
• Deficiency of immune interferon production by leukocytes of normal newborns.

  1980cited by this paper
• Interferon activation of "pre-spontaneous killer" (pre-SK) cells and alteration in kinetics of lysis of both "pre-SK" and active SK cells.

  1980cited by this paper
• Natural killer and killer cell activities in patients with primary immunodeficiencies or defects in immune interferon production

  1980cited by this paper
• Double-stranded RNA inhibits a phosphoprotein phosphatase present in interferon-treated cells.

  1980cited by this paper
• Interferon enhances protein degradation in Ehrlich ascites-tumour cells [proceedings].

  1980cited by this paper
• DISTINCT INTERFERON RESPONSES IN CULTURED MAMMALIAN CELLS

  1980cited by this paper
• PROPERTIES OF MOUSE IMMUNE T‐INTERFERON (TYPE II)

  1980cited by this paper
• Cellular and humoral immunity in the pathogenesis of recurrent herpes viral infections in patients with lymphoma.

  1980cited by this paper
• Enhanced cytotoxicity of mouse natural killer cells for vaccinia and herpes virus-infected targets.

  1980cited by this paper
• Common pathways of interferon and hormonal action

  1980cited by this paper
• Interferon inhibits the redistribution of cell surface components

  1980cited by this paper
• A family of structural genes for human lymphoblastoid (leukocyte-type) interferon

  1980cited by this paper
• Transfer of interferon-induced viral resistance from human leukocytes to other cell types

  1980cited by this paper
• Role of G0-G1 arrest in the inhibition of tumor cell growth by interferon.

  1980cited by this paper
• Inhibition of adipose conversion of BALB/c 3T3 cells by interferon and 12-O-tetradecanoylphorbol-13-acetate.

  1980cited by this paper
• Immune competence of newborn lymphocytes.

  1980cited by this paper
• Interferon effects on microfilament organization cellular fibronectin distribution, and cell motility in human fibroblasts

  1980cited by this paper
• Virus and interferon effects on cellular prostaglandin biosynthesis.

  1980cited by this paper
• Thymic deficiency in Down's syndrome.

  1979cited by this paper
• Effect of interferon on concentrations of cyclic nucleotides in cultured cells.

  1979cited by this paper
• Suppressive effect of interferon on erythroid cell proliferation.

  1979cited by this paper
• Genetics of the interferon system.

  1979cited by this paper
• Production of interferon in the murine mixed lymphocyte culture. II. Interferon production is a T cell‐dependent function, independent of proliferation

  1979cited by this paper
• Regulation of lymphocyte mitogenesis by (2′–5′) oligo-isoadenylate

  1979cited by this paper
• Susceptibility of various cells treated with interferon to the toxic effect of poly(rI).poly(rC) treatment.

  1979cited by this paper
• Impaired cell-mediated immune response in patients with congenital rubella: correlation with gestational age at time of infection.

  1979cited by this paper
• Nuclease activation by double-stranded RNA and by 2',5'-oligoadenylate in extracts of interferon-treated chick cells.

  1979cited by this paper
• Enhancement of carcinoembryonic antigen expression by interferon

  1979cited by this paper
• Interferon effects on the growth and division of human fibroblasts.

  1979cited by this paper
• Interferons: rationale for clinical trials in neoplastic disease.

  1979cited by this paper
• Suppression of the accumulation of steroid-inducible glutamine synthetase mRNA on embryonic chick retinal polysomes by interferon preparation.

  1979cited by this paper
• Augmentation of mouse natural killer cell activity by interferon and interferon inducers.

  1979cited by this paper
• Enzymatic induction of interferon production by galactose oxidase treatment of human lymphoid cells

  1979cited by this paper
• Natural Killer Cells: Characteristics and Regulation of Activity

  1979cited by this paper
• Effects of interferon inducing agents (polyriboinosinic acid. Polyribocytidylic acid, tilorone) on hepatic hemoproteins (cytochrome P-450, catalase, tryptophan 2,3-dioxygenase, mitochondrial cytochromes), heme metabolism and cytochrome P-450-linked monooxygenase systems.

  1979cited by this paper
• Impaired cellular immunity to cytomegalovirus in congenitally infected children and their mothers.

  1979cited by this paper
• Relationships of the structure and function of the interferon receptor to hormone receptors and establishment of the antiviral state.

  1978cited by this paper
• Interferon in nasal secretions from infants with viral respiratory tract infections.

  1978cited by this paper
• Interferon and spontaneous cytotoxicity in man. I. Enhancement of the spontaneous cytotoxicity of peripheral lymphocytes by human leukocyte interferon

  1978cited by this paper
• Role of interferon in the pathogenesis of viral diseases of mice as demonstrated by the use of anti-interferon serum. V. Protective role in mouse hepatitis virus type 3 infection of susceptible and resistant strains of mice.

  1978cited by this paper
• Enhancement of T cell cytotoxic responses by purified human fibroblast interferon.

  1978cited by this paper
• A syndrome associating partial albinism and immunodeficiency.

  1978cited by this paper
• Human leukocyte interferon for the treatment of herpes zoster in patients with cancer.

  1978cited by this paper
• Enhanced expression of beta2-microglobulin and HLA antigens on human lymphoid cells by interferon.

  1978cited by this paper
• Physical, morphological, and biochemical alterations in the membrane of AKR mouse cells after interferon treatment.

  1978cited by this paper
• Interferon affects both G1 and S+G2 in cells stimulated from quiescence to growth

  1978cited by this paper
• Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Identification of the anti-viral activity as interferon and characterization of the human effector lymphocyte subpopulation

  1978cited by this paper
• Preliminary observations on the effect of human leukocyte interferon in non-Hodgkin's lymphoma.

  1978cited by this paper
• Persistent Epstein-Barr virus infection in a child with hypergammaglobulinaemia and immunoblastic proliferation associated with a selective defect in immune interferon secretion.

  1978cited by this paper
• Characteristics of human lymphoblastoid (Namalva) interferon.

  1978cited by this paper
• Proliferative and interferon responses by peripheral blood mononuclear cells after bone marrow transplantation in humans

  1978cited by this paper
• Regulation of mitogen-induced lymphocyte DNA synthesis by human interferon of different origins.

  1978cited by this paper
• Antiviral activity in sera of patients with influenza infection.

  1978cited by this paper
• Cell-Mediated Immunity to Cytomegalovirus Infection in Normal Subjects and Cardiac Transplant Patients

  1978cited by this paper
• Enhancement of IgE-mediated histamine release from human basophils by viruses: role of interferon

  1977cited by this paper
• Inhibition of transcription and translation of globin messenger RNA in dimethyl sulfoxide-stimulated Friend erythroleukemic cells treated with interferon.

  1977cited by this paper
• Transfer factor therapy in ataxia--telangiectasia.

  1977cited by this paper
• A viremic phase for herpes zoster in children with cancer.

  1977cited by this paper
• Inhibition by anti-interferon serum of lymphocytic choriomeningitis virus disease in suckling mice.

  1977cited by this paper
• Decreased mononuclear and polymorphonuclear chemotaxis in human newborns, infants, and young children.

  1977cited by this paper
• Regulatory effect of interferon on T cells in vitro.

  1976cited by this paper
• Role of interferon in the pathogenesis of virus diseases in mice as demonstrated by the use of anti-interferon serum. I. Rapid evolution of encephalomyocarditis virus infection

  1976cited by this paper
• Hyaluronic acid produced by human synovial fibroblasts. Effect of polyinosinic-polycytidylic acid (poly I:C) and interferon.

  1976cited by this paper
• Role of interferon in the pathogenesis of virus diseases in mice as demonstrated by the use of anti-interferon serum. II. Studies with herpes simplex, Moloney sarcoma, vesicular stomatitis, Newcastle disease, and influenza viruses

  1976cited by this paper
• The nature of the suppressive effect of interferon and interferon inducers on the in vitro immune response.

  1976cited by this paper
• Effect of leukocyte interferon on urinary excretion of cytomegalovirus by infants.

  1976cited by this paper
• Interferon and delayed-type hypersensitivity to a viral antigen.

  1976cited by this paper
• Effect of human leukocyte interferon on hepatitis B virus infection in patients with chronic active hepatitis.

  1976cited by this paper
• Inhibition of the primary in vitro antibody response by interferon preparations.

  1975cited by this paper
• Decreased interferon response by lymphocytes from children with chronic hepatitis.

  1975cited by this paper
• Interferon inhibition of autogenously induced virions (C particles) in synchronized L-929 cell cultures.

  1974cited by this paper
• IMPAIRED INTERFERON RESPONSE OF CHILDREN WITH CONGENITAL CYTOMEGALOVIRUS DISEASE

  1974cited by this paper
• Host defenses against viral disease.

  1974cited by this paper
• Evaluation of T lymphocyte effector function in immunodeficiency diseases: abnormality in mitogen-stimulated interferon in patients with selective IgA deficiency.

  1974cited by this paper
• Effect of Human Leukocyte Interferon on the Response of Lymphocytes to Mitogenic Stimuli In Vitro

  1974cited by this paper
• Establishment and Maintenance of the Interferon-Induced Antiviral State: Studies in Enucleated Cells

  1974cited by this paper
• In vitro leukocyte interferon production in patients with Hodgkin's disease.

  1974cited by this paper
• Chronic lymphocytic leukaemia. Studies on mitogen-stimulated lymphocyte interferon as a new technique for assessing T lymphocyte effector function.

  1974cited by this paper
• Impaired production of interferon in lymphocytes from immunosuppressed patients.

  1973cited by this paper
• Stimulation of Aryl Hydrocarbon Hydroxylase Induction in Cell Cultures by Interferon

  1973cited by this paper
• Enhancement by interferon of the expression of surface antigens on murine leukemia L 1210 cells.

  1973cited by this paper
• Interferon and cell division. VIII. Effect of interferon on macromolecular synthesis in L1210 cells in vitro

  1973cited by this paper
• Variations in interferon production by lymphocytes from patients with chronic lymphatic leukaemia

  1972cited by this paper
• Interferon, antibody, and other host factors in herpes zoster.

  1972cited by this paper
• The interferons and their inducers: molecular and therapeutic considerations. 2.

  1972cited by this paper
• Suppression of the Intracellular Growth of Shigella flexneri in Cell Cultures by Interferon Preparations and Polyinosinic-Polycytidylic Acid

  1972cited by this paper
• Viral infections in man associated with acquired immunological deficiency states.

  1971cited by this paper
• Effect of antilymphocytic serum on circulating interferon in mice as a function of the inducer.

  1971cited by this paper
• Comparative Production of Interferon by Human Fetal, Neonatal, and Maternal Cells

  1971cited by this paper
• Inducers of interferon inhibit the mitotic response of liver cells to partial hepatectomy.

  1971cited by this paper
• Suppression of interferon response in lymphocytes from patients with uremia.

  1971cited by this paper
• Immunosuppression, interferon, and viral infections.

  1971cited by this paper
• Differing Susceptibility of Adolescent and Adult Mice to Non-lethal Infection with Coxsackievirus B3 1

  1971cited by this paper
• Interferon response of lymphocytes in disorders with decreased resistance to infections.

  1970cited by this paper

• Mycosis Fungoides

  2015cites this paper
• DRUG SELECTION PERSPECTIVES

  2013cites this paper
• Avaliação da carga viral do virus da hepatite C em diferentes compartimentos biológicos: influência na predição da recidiva virológica

  2013cites this paper
• PROGRAMA DE PÓS-GRADUAÇÃO EM PESQUISA E DESENVOLVIMENTO - BIOTECNOLOGIA MÉDICA MESTRADO PROFISSIONAL

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• Downregulation of Interferon a but Not y Receptor Expression In Vivo in the Acquired Immunodeficiency Syndrome

  2013cites this paper
• Management of Hepatitis C Virus-Related Arthritis

  2012cites this paper
• A comparative study on the efficacy of different dosage of alpha-interferon treatment in patients with chronic hepatitis B

  2007cites this paper
• Passive and active components of neonatal innate immune defenses

  2005cites this paper
• The case for hepatitis C arthritis.

  2004cites this paper
• Hearing Loss as a Complication of Peginterferon Alfa 2a Combination Therapy in a Patient with Hepatitis C Virus Infection

  2004cites this paper
• A pilot study to test the efficacy of oral administration of interferon-alpha lozenges to patients with Sjögren's syndrome.

  2003cites this paper
• y-Interferon Modulates von Willebrand Factor Release by Cultured Human Endothelial Cells

  2003cites this paper
• Viewpoint on the impact of interferon in the treatment of multiple myeloma: benefit for a small proportion of patients?

  2000cites this paper
• Durable loss of a malignant T-cell clone in a stage IV cutaneous T-cell lymphoma patient treated with high-dose interferon and photopheresis.

  1999cites this paper
• Sudden hearing loss in a patient hepatitis C virus (HCV) positive on therapy with alpha-interferon: a possible autoimmune-microvascular pathogenesis

  1998cites this paper
• Therapy for chronic hepatitis B infection.

  1996cites this paper
• A survey of adverse events in 11,241 patients with chronic viral hepatitis treated with alfa interferon.

  1996cites this paper
• Respiratory virus infection in chronic chest disease.

  1995cites this paper
• Interferon‐α2a for chronic hepatitis B with e antigen or antibody: comparable antiviral effects on wild‐type virus and precore mutant

  1995cites this paper
• Interrelationship of fever, immune response and aging in mice.

  1995cites this paper
• Occurrence of a T cell lymphoma in a patient with chronic myeloid leukemia treated with alpha interferon.

  1995cites this paper
• [Interferon production in peripheral blood cells of patients with pulmonary mycobacterial disease].

  1995cites this paper
• Cyclosporine treatment reduces early atherosclerosis in the cholesterol-fed rabbit.

  1995cites this paper
• Immunotherapy for Multiple Sclerosis

  1994cites this paper
• The treatment of choroidal neovascular membranes by alpha interferon. An efficacy and toxicity study.

  1994cites this paper
• Interferon beta-1b.

  1994cites this paper
• Detection of interferon‐alpha expression by PCR in patients with chronic hepatitis C and hepatitis non‐A, non‐B

  1994cites this paper
• Phenotypical and functional characterization of Fey receptor I (CD64)‐negative monocytes, a minor human monocyte subpopulation with high accessory and antiviral activity

  1993cites this paper
• Fetal plasma interferon gamma concentration in normal pregnancy.

  1993cites this paper
• The effect of a single course of alpha-2B-interferon in patients with HIV-related and chronic idiopathic immune thrombocytopenia.

  1993cites this paper
• Treatment of schizophrenic disorder, paranoid type, with intramuscular recombinant alpha-2b interferon

  1993cites this paper
• Intermolecular homologies of human interferon-alpha.

  1992cites this paper
• A randomized controlled trial of lymphoblastoid interferon‐α in patients with chronic hepatitis B lacking HBeAg

  1992cites this paper
• Interferons 1992

  1992cites this paper
• Systemic interferon‐alpha in the treatment of HTLV‐I‐associated myelopathy

  1992cites this paper
• Production of epithelial cell growth factors by lamina propria mononuclear cells.

  1992cites this paper
• Zidovudine-Interferon-α Combination Therapy in Patients with Advanced Human Immunodeficiency Virus Type 1 Infection: Biphasic Response of p24 Antigen and Quantitative Polymerase Chain Reaction

  1992cites this paper
• Recombinant interferon‐α2A as maintenance treatment for patients with advanced stage chronic lymphocytic leukemia responding to chemotherapy

  1992cites this paper
• Interferon‐α receptor expression and regulation in chronic hepatitis B virus infection

  1991cites this paper
• A phase I trial of α-interferon in combination with pentostatin in hematologic malignancies

  1991cites this paper
• Kaposi's Sarcoma in a child after autologous bone marrow transplantation for non‐Hodgkin's lymphoma

  1991cites this paper
• Autoantibodies during α‐interferon therapy for chronic hepatitis B

  1991cites this paper
• Combined therapy for Sézary syndrome with extracorporeal photochemotherapy and low-dose interferon alfa therapy. Clinical, molecular, and immunologic observations.

  1991cites this paper
• Psoriasis induced by interferon‐α

  1991cites this paper
• Treatment of early stage-B chronic lymphocytic leukemia with alpha-2b interferon after chlorambucil reduction of the tumoral mass

  1991cites this paper
• Immunotherapy of Lung Cancer

  1991cites this paper
• Patterns of Interferon-γ Production by Peripheral Blood Mononuclear Cells from Patients with Human Immunodeficiency Virus Infection

  1990cites this paper
• Therapeutic approaches to neoplasms in AIDS.

  1990cites this paper
• Long-term follow-up of 120 patients with AIDS-related Kaposi's sarcoma treated with interferon alpha-2a.

  1990cites this paper
• Genital Warts and Intralesional Injections of Interferon

  1990cites this paper
• Concomitant Effect of 2′‐Deoxycoformycin on Natural Killer Cell Activity and Tumour Cell Sensitivity to Lysis in Hairy Cell Leukaemia—Discordant Effects of Alpha Interferon

  1990cites this paper
• Acute myelofibrosis: response to recombinant human interferon alpha-2a.

  1990cites this paper
• Immunosuppression and Human Malignancy

  1990cites this paper
• The effect of topical interferon alpha 2b on actinic keratoses.

  1990cites this paper
• Genital Papillomavirus Infections

  1990cites this paper
• Recombinant human γ‐interferon in patients with chronic active hepatitis B: Pharmacokinetics, tolerance and biological effects

  1990cites this paper
• RYODORAKU ELECTRICAL ACUPUNCTURES, , KAMPO HERBAL MEDICINES, AND FOOD-LIFE ENVIRONMENT FOR AGING PERSON (Pert-2):Especially the Immunology concerning to Immunoglobulin Gene and its Component Changes

  1990cites this paper
• Interferone bei chronischen Virushepatitiden

  1990cites this paper
• The effect of an intralesional sustained-release formulation of interferon alfa-2b on basal cell carcinomas.

  1990cites this paper
• The effect of intralesional interferon gamma on basal cell carcinomas.

  1990cites this paper
• Characterization and Functions of the Natural Suppressor Cell Systems

  1989cites this paper
• Gastrointestinal Carcinoid Tumours: Histogenetic, Histochemical, Immunohistochemical, Clinical and Therapeutic Aspects

  1989cites this paper
• Nuclear DNA distribution in neuroendocrine gastroenteropancreatic tumors before and during treatment.

  1989cites this paper
• The Blood-Brain Barrier and the Immune System

  1989cites this paper
• Interferon alfa-2a in the treatment of cutaneous T cell lymphoma.

  1989cites this paper
• Bone Marrow Microenvironment

  1989cites this paper
• Viral Infections and the Blood-Brain Barrier

  1989cites this paper
• INTERFERON ALPHA‐2b THERAPY IN ADULT CHRONIC THROMBOCYTOPENIC PURPURA (ITP)

  1989cites this paper
• A case of hepatocellular carcinoma treated with recombinant interleukin 2 who showed abrupt decrease of serum alfafetoprotein concentration

  1988cites this paper
• Defects in Host-Defense Mechanisms

  1988cites this paper
• Downregulation of interferon alpha but not gamma receptor expression in vivo in the acquired immunodeficiency syndrome.

  1988cites this paper
• QUALITATIVE STUDIES ON α‐INTERFERON‐2b IN PROLONGED CONTINUOUS INFUSION REGIMES USING GRADIENT ELUTION HIGH‐PERFORMANCE LIQUID CHROMATOGRAPHY

  1988cites this paper
• Interferon gamma production by human intestinal mucosal mononuclear cells. Decreased levels in inflammatory bowel disease.

  1988cites this paper
• Discordant effect of interferon on natural killer activity and tumor cell sensitivity to lysis in hairy cell leukemia.

  1988cites this paper
• Interferon-gamma, the activated macrophage, and host defense against microbial challenge.

  1988cites this paper
• Immunodeficiency and Disease

  1988cites this paper
• Antiproliferative and Clinical Antitumor Effects of Interferons

  1988cites this paper
• Review: the treatment of hepatocellular carcinoma

  1988cites this paper
• Kaposi's sarcoma in AIDS patients: Long-term treatment with recombinant interferon alpha-2A and chemotherapy

  1988cites this paper
• Nursing management of patients receiving interferon.

  1988cites this paper
• FURTHER EVIDENCE OF THE EFFICACY OF INTERFERON FOR T‐CELL HAIRY CELL LEUKAEMIA: To the Editor:

  1988cites this paper
• Virostatische Therapie der chronischen Hepatitis

  1988cites this paper
• Interferon γ production by human intestinal mucosal mononuclear cells

  1988cites this paper
• Zytokine in der klinischen Anwendung

  1988cites this paper
• Intracerebral Beta‐Interferon in Brain Tumor Therapy Monitoring Cerebral Function with Compressed Spectral Analysis a

  1988cites this paper
• Pulmonary Sarcoidosis Following Interferon Therapy for Advanced Renal Cell Carcinoma

  1987cites this paper
• New antiviral compounds and impact in management of neoplastic disease and AIDS

  1987cites this paper
• Induction of acute corneal allograft rejection by alpha-2 interferon.

  1987cites this paper
• Pharmacokinetics of Interferon α‐2b in Healthy Volunteers

  1987cites this paper
• Inhibition of Mammalian DNA Polymerases by Recombinant α-Interferon and γ-Interferon

  1987cites this paper
• Recombinant interferon alfa-2b in plaque-phase mycosis fungoides. Intralesional and low-dose intramuscular therapy.

  1987cites this paper
• Immune interventions in disease.

  1987cites this paper
• Prophylactic use of human leukocyte interferon after allogeneic marrow transplantation.

  1987cites this paper
• Activation of Murine Polymorphonuclear Neutrophils for Fungicidal Activity by Recombinant Gamma Interferon

  1987cites this paper
• Viral Infection and Immunity

  1986cites this paper
• Intralesional recombinant alpha-2 interferon for the treatment of patients with condyloma acuminatum or verruca plantaris.

  1986cites this paper
• Effects of Recombinant Human Leukocyte Interferon Treatment on Endogenous Interferon Production in Patients with Chronic Type-B Hepatitis

  1986cites this paper
• Effects of gold compounds on function of phagocytic cells

  1986cites this paper
• Human lymphoblastoid interferon. In vitro and in vivo studies in hepatocellular carcinoma.

  1986cites this paper
• Treatment of basal cell carcinoma with intralesional interferon.

  1986cites this paper